Acute posterior multifocal placoid pigment epitheliopathy resembling multiple sclerosis
Research output: Contribution to journal › Journal article › Research › peer-review
A 23-year-old man presented with right eye blurred vision; he was diagnosed with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), and his symptoms resolved with prednisolone. Two months later, he developed a right arm weakness that resolved after 3 weeks. MR scan of brain identified changes suggesting multiple sclerosis, with four hyperintense FLAIR lesions; there was contrast enhancement of two lesions and no diffusion restriction. Cerebrospinal fluid showed mononuclear pleocytosis. We eventually diagnosed these as APMPPE-associated CNS lesions. APMPPE is a rare inflammatory chorioretinopathy that rarely can resemble multiple sclerosis clinically and radiologically.
Original language | English |
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Journal | Practical Neurology |
Volume | 22 |
Issue number | 6 |
Pages (from-to) | 515-517 |
Number of pages | 3 |
ISSN | 1474-7758 |
DOIs | |
Publication status | Published - 2022 |
Bibliographical note
Publisher Copyright:
© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.
- MRI, multiple sclerosis, ophthalmology, stroke, vasculitis
Research areas
ID: 327139549