NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017: a nationwide cohort study

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017 : a nationwide cohort study. / Eriksen, Patrick R. G.; Clasen-Linde, Erik; Brown, Peter de Nully; Haunstrup, Laura; Christoffersen, Mette; Asdahl, Peter; Thomsen, Troels Moller; von Buchwald, Christian; Heegaard, Steffen.

In: Leukemia and Lymphoma, Vol. 63, No. 11, 2022, p. 2579-2588.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Eriksen, PRG, Clasen-Linde, E, Brown, PDN, Haunstrup, L, Christoffersen, M, Asdahl, P, Thomsen, TM, von Buchwald, C & Heegaard, S 2022, 'NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017: a nationwide cohort study', Leukemia and Lymphoma, vol. 63, no. 11, pp. 2579-2588. https://doi.org/10.1080/10428194.2022.2087069

APA

Eriksen, P. R. G., Clasen-Linde, E., Brown, P. D. N., Haunstrup, L., Christoffersen, M., Asdahl, P., Thomsen, T. M., von Buchwald, C., & Heegaard, S. (2022). NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017: a nationwide cohort study. Leukemia and Lymphoma, 63(11), 2579-2588. https://doi.org/10.1080/10428194.2022.2087069

Vancouver

Eriksen PRG, Clasen-Linde E, Brown PDN, Haunstrup L, Christoffersen M, Asdahl P et al. NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017: a nationwide cohort study. Leukemia and Lymphoma. 2022;63(11):2579-2588. https://doi.org/10.1080/10428194.2022.2087069

Author

Eriksen, Patrick R. G. ; Clasen-Linde, Erik ; Brown, Peter de Nully ; Haunstrup, Laura ; Christoffersen, Mette ; Asdahl, Peter ; Thomsen, Troels Moller ; von Buchwald, Christian ; Heegaard, Steffen. / NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017 : a nationwide cohort study. In: Leukemia and Lymphoma. 2022 ; Vol. 63, No. 11. pp. 2579-2588.

Bibtex

@article{b1ac62b8de37417d8ba5fc9042a0a90b,
title = "NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017: a nationwide cohort study",
abstract = "Compared to Asian and Latin American populations, sinonasal NK- or T-cell lymphoma is rare in Europe. All patients with sinonasal NK- or T-cell lymphoma in Denmark from 1980 to 2017 were validated histologically, and the disease behavior and demographics were extracted from medical records and national registries. Prognostic factors associated with mortality were determined using survival statistics. We included 56 patients: 40 extranodal NK/T-cell lymphoma (nasal type) (ENKTCL) and 16 peripheral T-cell lymphoma (not otherwise specified) (PTCL). The median age was 66, and most patients were male (72%). The ENKTCL and PTCL 5-year overall survival was 48% and 50%, respectively; progression-free survival was 38% for both. With ENKTCL, stage and performance status increased mortality significantly (HR = 8.6; p < 0.001 and HR = 4.23; p = 0.04). In conclusion, disseminated disease had a dismal outcome and the onset of ENKTCL in this ethnically homogeneous European cohort was about a decade later than reported in Asian populations.",
keywords = "Extranodal lymphoma, paranasal neoplasms, nasal neoplasms, prognosis, demography, natural killer cell, T-cell, CLINICAL DIFFERENCES",
author = "Eriksen, {Patrick R. G.} and Erik Clasen-Linde and Brown, {Peter de Nully} and Laura Haunstrup and Mette Christoffersen and Peter Asdahl and Thomsen, {Troels Moller} and {von Buchwald}, Christian and Steffen Heegaard",
year = "2022",
doi = "10.1080/10428194.2022.2087069",
language = "English",
volume = "63",
pages = "2579--2588",
journal = "Leukemia and Lymphoma",
issn = "1042-8194",
publisher = "Taylor & Francis",
number = "11",

}

RIS

TY - JOUR

T1 - NK- and T-cell lymphoma of the nasal cavity and paranasal sinuses in Denmark 1980-2017

T2 - a nationwide cohort study

AU - Eriksen, Patrick R. G.

AU - Clasen-Linde, Erik

AU - Brown, Peter de Nully

AU - Haunstrup, Laura

AU - Christoffersen, Mette

AU - Asdahl, Peter

AU - Thomsen, Troels Moller

AU - von Buchwald, Christian

AU - Heegaard, Steffen

PY - 2022

Y1 - 2022

N2 - Compared to Asian and Latin American populations, sinonasal NK- or T-cell lymphoma is rare in Europe. All patients with sinonasal NK- or T-cell lymphoma in Denmark from 1980 to 2017 were validated histologically, and the disease behavior and demographics were extracted from medical records and national registries. Prognostic factors associated with mortality were determined using survival statistics. We included 56 patients: 40 extranodal NK/T-cell lymphoma (nasal type) (ENKTCL) and 16 peripheral T-cell lymphoma (not otherwise specified) (PTCL). The median age was 66, and most patients were male (72%). The ENKTCL and PTCL 5-year overall survival was 48% and 50%, respectively; progression-free survival was 38% for both. With ENKTCL, stage and performance status increased mortality significantly (HR = 8.6; p < 0.001 and HR = 4.23; p = 0.04). In conclusion, disseminated disease had a dismal outcome and the onset of ENKTCL in this ethnically homogeneous European cohort was about a decade later than reported in Asian populations.

AB - Compared to Asian and Latin American populations, sinonasal NK- or T-cell lymphoma is rare in Europe. All patients with sinonasal NK- or T-cell lymphoma in Denmark from 1980 to 2017 were validated histologically, and the disease behavior and demographics were extracted from medical records and national registries. Prognostic factors associated with mortality were determined using survival statistics. We included 56 patients: 40 extranodal NK/T-cell lymphoma (nasal type) (ENKTCL) and 16 peripheral T-cell lymphoma (not otherwise specified) (PTCL). The median age was 66, and most patients were male (72%). The ENKTCL and PTCL 5-year overall survival was 48% and 50%, respectively; progression-free survival was 38% for both. With ENKTCL, stage and performance status increased mortality significantly (HR = 8.6; p < 0.001 and HR = 4.23; p = 0.04). In conclusion, disseminated disease had a dismal outcome and the onset of ENKTCL in this ethnically homogeneous European cohort was about a decade later than reported in Asian populations.

KW - Extranodal lymphoma

KW - paranasal neoplasms

KW - nasal neoplasms

KW - prognosis

KW - demography

KW - natural killer cell

KW - T-cell

KW - CLINICAL DIFFERENCES

U2 - 10.1080/10428194.2022.2087069

DO - 10.1080/10428194.2022.2087069

M3 - Journal article

C2 - 35699970

VL - 63

SP - 2579

EP - 2588

JO - Leukemia and Lymphoma

JF - Leukemia and Lymphoma

SN - 1042-8194

IS - 11

ER -

ID: 314445694