Niels Erik Skakkebæk
Affiliate Professor
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Early breast development in girls after prenatal exposure to non-persistent pesticides
Veje, C. W., Andersen, H. R., Schmidt, I. M., Aksglaede, L., Sørensen, K., Juul, Anders, Jensen, T. K., Grandjean, P., Skakkebæk, Niels Erik & Main, Katharina Maria, 2012, In: International Journal of Andrology. 35, 3, p. 273-82Research output: Contribution to journal › Journal article › Research › peer-review
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Early puberty in internationally adopted girls: hormonal and clinical markers of puberty in 276 girls examined biannually over two years
Teilmann, Grete Katrine, Petersen, Jørgen Holm, Gormsen, M., Damgaard, K., Skakkebæk, Niels Erik, Jensen, T. K., Teilmann, Grete Katrine, Petersen, J. H., Gormsen, M., Damgaard, K., Skakkebæk, Niels Erik & Jensen, T. K., 1 Jan 2009, In: Hormone Research. 72, 4, p. 236-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of growth hormone replacement therapy on IGF-related parameters and on the pituitary-gonadal axis in GH-deficient males. A double-blind, placebo-controlled crossover study
Juul, Anders, Andersson, A. M., Pedersen, S. A., Jørgensen, J. O., Christiansen, J. S., Groome, N. P. & Skakkebæk, Niels Erik, 1998, In: Hormone Research. 49, 6, p. 269-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling
Almstrup, Kristian, Høi-Hansen, Christina Engel, Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jul 2004, In: Cancer Research. 64, 14, p. 4736-4743 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endocrine Disrupting Chemicals and Risk of Testicular Cancer A Systematic Review and Meta-analysis
Bräuner, E. V., Lim, Youn-Hee, Koch, T., Uldbjerg, C. S., Gregersen, L. S., Pedersen, M. K., Frederiksen, H., Petersen, Jørgen Holm, Coull, B. A., Andersson, A., Hickey, M., Skakkebæk, Niels Erik, Hauser, R. & Juul, Anders, 2021, In: The Journal of clinical endocrinology and metabolism. 106, 12, p. e4834–e4860 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endocrine disrupters: we need research, biomonitoring and action
Andersson, A., Bay, K., Frederiksen, H. & Skakkebæk, Niels Erik, Jul 2016, In: Andrology. 4, 4, p. 556-60 5 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Endocrine function in patients treated for carcinoma in situ in the testis with irradiation
Petersen, P. M., Daugaard, G., Rørth, M. & Skakkebæk, Niels Erik, 2003, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 111, 1, p. 93-8; discussion 98-9Research output: Contribution to journal › Journal article › Research › peer-review
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Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society
Zoeller, R. T., Brown, T. R., Doan, L. L., Gore, A. C., Skakkebæk, Niels Erik, Soto, A. M., Woodruff, T. J. & Vom Saal, F. S., 2012, In: Endocrinology. 153, 9, p. 4097-110 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Environment, testicular dysgenesis and carcinoma in situ testis
Olesen, I. A., Sonne, Si Brask, Hoei-Hansen, C. E., Rajpert-DeMeyts, E. & Skakkebæk, Niels Erik, 2007, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 21, 3, p. 462-78 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Environmental factors and puberty timing: expert panel research needs
Louis, G. M. B., Jr, L. E. G., Marcus, M., Ojeda, S. R., Pescovitz, O. H., Witchel, S. F., Sippell, W., Abbott, D. H., Soto, A., Tyl, R. W., Bourguignon, J. P., Swan, S. H., Golub, M. S., Wabitsch, M., Toppari, J., Euling, S. Y. & Skakkebæk, Niels Erik, 2008, In: Pediatrics. 121 Suppl 3, p. S192-S207Research output: Contribution to journal › Journal article › Research › peer-review
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Environmental factors in declining human fertility
Skakkebæk, Niels Erik, Lindahl-Jacobsen, R., Levine, H., Andersson, A., Jørgensen, N., Main, Katharina Maria, Lidegaard, Øjvind, Priskorn, Lærke, Holmboe, S. A., Bräuner, E. V., Almstrup, Kristian, Franca, L. R., Znaor, A., Kortenkamp, A., Hart, R. J. & Juul, Anders, 2022, In: Nature Reviews Endocrinology. 18, p. 139–157Research output: Contribution to journal › Review › Research › peer-review
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Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells
Kristensen, D. G., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Almstrup, Kristian, 2013, In: International Journal of Developmental Biology. 57, 2-4, p. 309-317 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Erratum: PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men (Human Reproduction (2013) 28 (599-608))
Joensen, Ulla Nordström, Veyrand, B., Antignac, J. P., Jensen, Martin Blomberg, Petersen, Jørgen Holm, Marchand, P., Skakkebæk, Niels Erik, Andersson, A. M., Le Bizec, B. & Jorgensen, N., 2014, In: Human Reproduction. 29, 7, p. 1600 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part II
Krege, S., Beyer, J., Souchon, R., Albers, P., Albrecht, W., Algaba, F., Bamberg, M., Bodrogi, I., Bokemeyer, C., Cavallin-Ståhl, E., Classen, J., Clemm, C., Cohn-Cedermark, G., Culine, S., Daugaard, G., De Mulder, P. H. M., De Santis, M., de Wit, M., de Wit, R., Derigs, H. G. & 63 others, , 2007, In: European Urology. 53, 3, p. 497-513 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I
Krege, S., Beyer, J., Souchon, R., Albers, P., Albrecht, W., Algaba, F., Bamberg, M., Bodrogi, I., Bokemeyer, C., Cavallin-Ståhl, E., Classen, J., Clemm, C., Cohn-Cedermark, G., Culine, S., Daugaard, G., De Mulder, P. H. M., De Santis, M., de Wit, M., de Wit, R., Derigs, H. G. & 63 others, , 2007, In: European Urology. 53, 3, p. 478-496 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for decreasing quality of semen during past 50 years
Carlsen, E., Giwercman, A., Keiding, N. & Skakkebæk, Niels Erik, Mar 1993, In: Obstetrical & Gynecological Survey. 48, 3, p. 200-201 2 p.Research output: Contribution to journal › Review › Research › peer-review
Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis
Kristensen, D. G., Nielsen, J. E., Jørgensen, A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Almstrup, Kristian, 4 Feb 2014, In: British Journal of Cancer. 110, 3, p. 668-678 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window
van den Driesche, S., Kilcoyne, K. R., Wagner, I., Rebourcet, D., Boyle, A., Mitchell, R., McKinnell, C., Macpherson, S., Donat, R., Shukla, C. J., Jorgensen, A., Meyts, E. R., Skakkebæk, Niels Erik & Sharpe, R. M., 2017, In: JCI insight. 2, 6, 20 p., e91204.Research output: Contribution to journal › Journal article › Research › peer-review
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Exposure to UV filters during summer and winter in Danish kindergarten children
Krause, M., Andersson, A., Skakkebæk, Niels Erik & Frederiksen, H., Feb 2017, In: Environment International. 99, p. 177-184 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exposure to phenols, parabens and UV filters: Associations with loss-of-function mutations in the filaggrin gene in men from the general population
Joensen, U. N., Jørgensen, N., Thyssen, Jacob Pontoppidan, Petersen, Jørgen Holm, Szecsi, P. B., Stender, S., Andersson, A. M., Skakkebæk, Niels Erik & Frederiksen, H., 2017, In: Environment International. 105, p. 105-111Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of the vitamin D metabolizing enzyme CYP24A1 at the annulus of human spermatozoa may serve as a novel marker of semen quality
Jensen, Martin Blomberg, Jørgensen, A., Nielsen, Jens Erik Klint, Bjerrum, P. J., Skalkam, M., Petersen, Jørgen Holm, Egeberg, D. L., Bangsbøll, S., Andersen, A. N., Skakkebæk, Niels Erik, Juul, Anders, Rajpert-De Meyts, E., Dissing, Steen, Leffers, H. & Jørgensen, N., 2012, In: International Journal of Andrology. 35, 4, p. 499-510 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Falling sperm quality
Keiding, N., Giwercman, A., Carlsen, E. & Skakkebæk, Niels Erik, 9 Jul 1994, In: BMJ. 309, 6947, p. 131-131 1 p.Research output: Contribution to journal › Comment/debate › Research
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Familial resemblance in markers of testicular function in fathers and their young sons: a cross-sectional study
Priskorn, L., Joensen, Ulla Nordström, Petersen, Jørgen Holm, Jensen, T. K., Skakkebæk, Niels Erik & Jørgensen, N., 2021, In: Human reproduction (Oxford, England). 36, 3, p. 543-550 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing
Crain, D. A., Janssen, S. J., Edwards, T. M., Heindel, J., Ho, S., Hunt, P., Iguchi, T., Juul, Anders, McLachlan, J. A., Schwartz, J., Skakkebæk, Niels Erik, Soto, A. M., Swan, S., Walker, C., Woodruff, T. K., Woodruff, T. J., Giudice, L. C. & Guillette, L. J., 2008, In: Fertility and Sterility. 90, 4, p. 911-40 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general population
Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Mar 2007, In: American Journal of Epidemiology. 165, 5, p. 583-90 8 p.Research output: Contribution to journal › Journal article › Research
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Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm
Birch, M. R., Dissing, Steen, Skakkebæk, Niels Erik & Rehfeld, Anders Aagaard, 2021, In: Reproduction. 161, 5, p. 561-572 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Free insulin-like growth factor I serum levels in 1430 healthy children and adults, and its diagnostic value in patients suspected of growth hormone deficiency
Juul, Anders, Holm, Kirsten, Kastrup, K. W., Pedersen, S. A., Michaelsen, K. F., Scheike, T. H., Rasmussen, S., Müller, J. & Skakkebæk, Niels Erik, 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 8, p. 2497-502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Free testosterone and cardiometabolic parameters in men: Comparison of algorithms
Holmboe, S. A., Jasuja, R., Lawney, B., Priskorn, L., Joergensen, N., Linneberg, Allan René, Jensen, T. K., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A. M., 2021, In: Endocrine Connections. 10, 2, p. 220-229 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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From embryonic stem cells to testicular germ cell cancer-- should we be concerned?
Almstrup, Kristian, Sonne, Si Brask, Hoei-Hansen, C. E., Ottesen, A. M., Nielsen, J. E., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: International Journal of Andrology. 29, 1, p. 211-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GH-deficiency, sweating and thermoregulations
Juul, Anders, Main, Katharina Maria, Hjortskov, N., Jepsen, L., Nielsen, B., Halkjær-Kristensen, J. & Skakkebæk, Niels Erik, 1996, Growth Hormone in adults; Physiological and clinical aspects. p. 246 5 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Gene expression profiles of mouse spermatogenesis during recovery from irradiation
Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H., Almstrup, K., Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H. & Almstrup, Kristian, 1 Jan 2009, In: Reproductive Biology and Endocrinology. 7, p. 130Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variations in FSH action affect sex hormone levels and breast tissue size in infant girls: A pilot study
Henriksen, L. S., Hagen, C. P., Assens, M., Busch, A. S., Skakkebæk, Niels Erik, Almstrup, K. & Main, Katharina Maria, 1 Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3191-3198 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genital anomalies in boys and the environment
Main, Katharina Maria, Skakkebæk, Niels Erik, Virtanen, H. E. & Toppari, J., 1 Apr 2010, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 24, 2, p. 279-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer
Edsgärd, D., Dalgaard, M. D., Weinhold, N., Wesolowska-Andersen, A., Rajpert-De Meyts, E., Ottesen, A. M., Juul, Anders, Skakkebæk, Niels Erik, Skøt Jensen, T., Gupta, R., Leffers, H. & Brunak, S., 2013, In: Frontiers in Endocrinology. 4, p. 2Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours
Almstrup, Kristian, Høi-Hansen, Christina Engel, Nielsen, J. E., Wirkner, U., Ansorge, W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 23 May 2005, In: British Journal of Cancer. 92, 10, p. 1934-1941 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ
Almstrup, Kristian, Ottesen, A. M., Sonne, Si Brask, Hoei-Hansen, C. E., Leffers, H., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 2005, In: Cell and Tissue Research. 322, 1, p. 159-65 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Germ cell differentiation-dependent and stage-specific expression of LANCL1 in rodent testis
Nielsen, J. E., Hansen, M. A., Jørgensen, M., Tanaka, M., Almstrup, Kristian, Skakkebæk, Niels Erik & Leffers, H., 2003, In: European Journal of Histochemistry. 47, 3, p. 215-222 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Germ cell neoplasia in situ (GCNIS): evolution of the current nomenclature for testicular pre-invasive germ cell malignancy
Berney, D. M., Looijenga, L. H. J., Idrees, M., Oosterhuis, J. W., Rajpert-De Meyts, E., Ulbright, T. M. & Skakkebæk, Niels Erik, Jul 2016, In: Histopathology. 69, 1, p. 7-10 4 p.Research output: Contribution to journal › Review › Research › peer-review
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Germ cell neoplasia in situ and preserved fertility despite suppressed gonadotropins in a patient with testotoxicosis
Mortensen, L. J., Jensen, M. B., Christiansen, P., Rønholt, A. M., Jørgensen, A., Frederiksen, H., Nielsen, J. E., Loya, Anand Chainsukh, Grønkær Toft, B., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Juul, Anders, 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 12, p. 4411-4416 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Global patterns in testicular cancer incidence and mortality in 2020
Znaor, A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Kuliš, T., Laversanne, M., Gurney, J., Sarfati, D., McGlynn, K. A. & Bray, F., 2022, In: International Journal of Cancer. 151, 5, p. 692-698 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Goodbye International Journal of Andrology, welcome Andrology!
Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2012, In: International Journal of Andrology. 36, 6, p. 769-774 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Goodbye International Journal of Andrology, welcome Andrology!
Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2022, In: Andrology. 10, S2, p. 133-138Research output: Contribution to journal › Editorial › Research › peer-review
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Growth hormone (GH) provocative retesting of 108 young adults with childhood-onset GH deficiency and the diagnostic value of insulin-like growth factor I (IGF-I) and IGF-binding protein-3
Juul, Anders, Kastrup, K. W., Pedersen, S. A. & Skakkebæk, Niels Erik, 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 4, p. 1195-201 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth hormone (GH) treatment increases serum insulin-like growth factor binding protein-3, bone isoenzyme alkaline phosphatase and forearm bone mineral content in young adults with GH deficiency of childhood onset
Juul, Anders, Pedersen, S. A., Sørensen, S., Winkler, K., Jørgensen, J. O., Christiansen, J. S. & Skakkebæk, Niels Erik, 1994, In: European Journal of Endocrinology. 131, 1, p. 41-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth hormone (GH), exercise performance, muscle strength and sweat production in healthy subjects and adults with GH deficiency
Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 2000, Growth Hormone in adults; Physiological and clinical aspects. 2 ed. p. 281-300 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Growth hormone (GH)-deficiency in adults: clinical features and effects of GH substitution.
Jørgensen, J., Møller, J., Wolthers, T., Vahn, N., Juul, Anders, Skakkebæk, Niels Erik & Christiansen, J., 1994, In: The journal of pediatric endocrinology. p. 283-293 10 p.Research output: Contribution to journal › Journal article › Research
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Growth hormone deficiency and hyperthermia
Juul, Anders & Skakkebæk, Niels Erik, 1991, In: Lancet. 338, 8771, p. 887Research output: Contribution to journal › Journal article › Research › peer-review
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Growth hormone deficiency and hyperthermia during exercise: a controlled study of sixteen GH-deficient patients
Juul, Anders, Hjortskov, N., Jepsen, L., Nielsen, B., Halkjaer-Kristensen, J., Vahl, N., Jørgensen, J. O., Christiansen, J. S. & Skakkebæk, Niels Erik, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 11, p. 3335-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth hormone treatment during pregnancy in a growth hormone-deficient woman
Müller, J., Starup, J., Christiansen, J. S., Jørgensen, J. O., Juul, Anders & Skakkebæk, Niels Erik, 1995, In: European Journal of Endocrinology. 132, 6, p. 727-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth hormone treatment in GH-deficient adults; therapeutic and diagnostic aspects.
Juul, Anders, Jørgensen, J., müller, J. & Skakkebæk, Niels Erik, 1994, In: Clinical Pediatric Endocrinology. p. 63-71 8 p.Research output: Contribution to journal › Review › Research
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Growth hormone treatment of non-elderly adults with GH-deficiency
Christiansen, J., Jørgensen, J., Vahn, N., Juul, Anders, Müller, J. & Skakkebæk, Niels Erik, 1995, GHRH, GH and IGF-1: Basic and clinical Advances. p. 169-175 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Growth hormone, insulin-like growth factor I and its binding proteins 1 and 3 in last trimester intrauterine growth retardation with increased pulsatility index in the umbilical artery
Larsen, T., Main, Katharina Maria, Andersson, A. M., Juul, Anders, Greisen, Gorm & Skakkebæk, Niels Erik, 1996, In: Clinical Endocrinology. 45, 3, p. 315-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Habitual alcohol consumption associated with reduced semen quality and changes in reproductive hormones; a cross-sectional study among 1221 young Danish men
Jensen, T. K., Gottschau, M., Madsen, J. O. B., Andersson, A., Lassen, T. H., Skakkebæk, Niels Erik, Swan, S. H., Priskorn, L., Juul, Anders & Jørgensen, N., 2014, In: B M J Open. 4, 9, p. 1-11 11 p., e005462.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information
Edsgärd, D., Scheel, M., Hansen, N. T., Ralfkiaer, U., Jensen, T. S., Skakkebæk, Niels Erik, Brunak, S., Gupta, R., Rajpert-De Meyts, E. & Ottesen, A. M., 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e122-32Research output: Contribution to journal › Journal article › Research › peer-review
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High maternal age at first and subsequent child births in Denmark in the mid-1800s-Letter to the editor
Priskorn, L., Dahl, C. L., Pihl, A. S., Skakkebæk, Niels Erik & Juul, Anders, Oct 2019, In: European Journal of Obstetrics & Gynecology and Reproductive Biology. 241, p. 137-138 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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High normal testosterone levels in infants with non-mosaic Klinefelter's syndrome
Aksglaede, L., Petersen, Jørgen Holm, Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2007, In: European Journal of Endocrinology. 157, 3, p. 345-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer
Hoei-Hansen, C. E., Holm, M., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Jul 2003, In: Journal of Pathology. 200, 3, p. 370-4 5 p.Research output: Contribution to journal › Journal article › Research
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Histopathological Evaluation of Testicular Biopsy
Rajpert-de Meyts, E., Grigor, K. M. & Skakkebæk, Niels Erik, 2017, Endocrinology of the Testis and Male Reproduction. SimoniIlpo, M. & Huhtaniemi, I. (eds.). p. 1-20 (Endocrinology of the Testis and Male Reproduction).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Hormonal changes during GnRH analogue therapy in children with central precocious puberty
Müller, J., Juul, Anders, Andersson, A. M., Sehested, A. & Skakkebæk, Niels Erik, 2000, In: Journal of Pediatric Endocrinology and Metabolism. 13 Suppl 1, p. 739-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age
Main, Katharina Maria, Mortensen, G. K., Kaleva, M. M., Boisen, K. A., Damgaard, I. N., Chellakooty, M., Schmidt, I. M., Suomi, A., Virtanen, H. E., Petersen, J. H., Andersson, A., Toppari, J. & Skakkebæk, Niels Erik, 2006, In: Environmental Health Perspectives. 114, 2, p. 270-276 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men
Jørgensen, N., Joensen, Ulla Nordström, Jensen, T., Jensen, M., Almstrup, Kristian, Olesen, I., Juul, A., Andersson, A., Carlsen, E., Petersen, Jørgen Holm, Toppari, J. & Skakkebæk, Niels Erik, 2012, In: B M J Open. 2, 4, e000990.Research output: Contribution to journal › Journal article › Research › peer-review
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Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism
Rehfeld, Anders Aagaard, Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, Anders, Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human urinary excretion of non-persistent environmental chemicals: an overview of Danish data collected between 2006 and 2012
Frederiksen, H., Jensen, T. K., Jørgensen, N., Kyhl, H. B., Husby, S., Skakkebæk, Niels Erik, Main, Katharina Maria, Juul, Anders & Andersson, A., 2014, In: Reproduction. 147, 4, p. 555-565 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypothesis: Metformin is a potential reproductive toxicant
Tavlo, M., Skakkebæk, Niels Erik, Mathiesen, Elisabeth, Kristensen, D. M., Kjær, Kurt H., Andersson, A. & Lindahl-Jacobsen, R., 2022, In: Frontiers in Endocrinology. 13, 8 p., 1000872.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypothesis: exposure to endocrine-disrupting chemicals may interfere with timing of puberty
Mouritsen, Annette Korsholm, Aksglaede, L., Sørensen, K., Mogensen, S. S., Leffers, H., Main, Katharina Maria, Frederiksen, H., Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 346-59 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and expression profiling of 10 novel spermatid expressed CYPT genes
Hansen, M. A., Nielsen, J. E., Tanaka, M., Almstrup, Kristian, Skakkebæk, Niels Erik & Leffers, H., May 2006, In: Molecular Reproduction and Development. 73, 5, p. 568-579 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of genes differentially expressed in testes containing carcinoma in situ
Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-DeMeyts, E. & Leffers, H., Jun 2004, In: Molecular Human Reproduction. 10, 6, p. 423-431 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours
Sonne, Si Brask, Herlihy, A. S., Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, Kristian, Skakkebæk, Niels Erik, Marks, A., Leffers, H. & Rajpert-De Meyts, E., 2006, In: Virchows Archiv. 449, 2, p. 200-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunohistochemical expression of embryonal marker TRA-1-60 in carcinoma in situ and germ cell tumors of the testis
Giwercman, A., Andrews, P. W., Jørgensen, N., Müller, J., Graem, N. & Skakkebæk, Niels Erik, 15 Aug 1993, In: Cancer. 72, 4, p. 1308-14 7 p.Research output: Contribution to journal › Journal article › Research
- Published
Impact of growth hormone administration on other hormonal axes.
Jørgensen, J., Ovesen, P., Juul, Anders, Hansen, T., Skakkebæk, Niels Erik & Christiansen, J., 1999, In: Hormone Research. 51, p. 121-126 5 p.Research output: Contribution to journal › Review › Research
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Impact of psychological stress measured in three different scales on testis function: A cross-sectional study of 1362 young men
Nordkap, L., Priskorn, L., Bräuner, E. V., Hansen, Åse Marie, Kirstine Bang, A., Holmboe, S. A., Winge, S. B., Egeberg Palme, D. L., Mørup, N., Skakkebæk, Niels Erik, Kold Jensen, T. & Jørgensen, N., 2020, In: Andrology. 8, 6, p. 1674-1686 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired testicular function in patients with carcinoma-in-situ of the testis
Petersen, P. M., Giwercman, A., Hansen, S. W., Berthelsen, Jens, Daugaard, G., Rørth, M. & Skakkebæk, Niels Erik, 1999, In: Journal of Clinical Oncology. 17, 1, p. 173-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired thermoregulation in adults with growth hormone deficiency during heat exposure and exercise
Juul, Anders, Behrenscheer, A., Tims, T., Nielsen, B., Halkjaer-Kristensen, J. & Skakkebæk, Niels Erik, 1993, In: Clinical Endocrinology. 38, 3, p. 237-244 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved gene expression signature of testicular carcinoma in situ
Almstrup, Kristian, Leffers, H., Lothe, R. A., Skakkebæk, Niels Erik, Sonne, Si Brask, Nielsen, J. E., Rajpert-De Meyts, E. & Skotheim, R. I., 2007, In: International Journal of Andrology. 30, 4, p. 292-303Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in first morning voided urinary luteinizing hormone levels precedes the physical onset of puberty
Demir, A., Voutilainen, R., Juul, Anders, Dunkel, L., Alfthan, H., Skakkebæk, Niels Erik & Stenman, U. H., 1996, In: Journal of Clinical Endocrinology and Metabolism. 81, 8, p. 2963-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in maternal placental growth hormone during pregnancy and disappearance during parturition in normal and growth hormone-deficient pregnancies
Lønberg, U., Damm, Peter, Andersson, A., Main, Katharina Maria, Chellakooty, M., Lauenborg, J., Skakkebæk, Niels Erik & Juul, Anders, 1 Jan 2003, In: American Journal of Obstetrics and Gynecology. 188, 1, p. 247-51 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased expression of alpha- and beta-globin mRNAs at the pituitary following exposure to estrogen during the critical period of neonatal sex differentiation in the rat
Leffers, H., Navarro, V. M., Nielsen, J. E., Mayen, A., Pinilla, L., Dalgaard, M., Malagon, M. M., Castaño, J. P., Skakkebæk, Niels Erik, Aguilar, E. & Tena-Sempere, M., 1 Apr 2006, In: Journal of Steroid Biochemistry and Molecular Biology. 99, 1, p. 33-43 11 p.Research output: Contribution to journal › Journal article › Research
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Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle
Holm, M., Hoei-Hansen, C. E., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Oct 2003, In: Journal of Urology. 170, 4 Pt 1, p. 1163-7 5 p.Research output: Contribution to journal › Journal article › Research
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Increasing international efforts to understand and conquer testicular germ cell cancer
Rajpert-De Meyts, E., Daugaard, G., Almstrup, Kristian, Jørgensen, A., Rørth, M., Jørgensen, N., von der Maase, H. & Skakkebæk, Niels Erik, Jan 2015, In: Andrology. 3, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Increasing trends in childlessness in recent birth cohorts - a registry-based study of the total Danish male population born from 1945 to 1980
Priskorn, L., Holmboe, S., Jacobsen, R., Jensen, T. K., Lassen, T. H. & Skakkebæk, Niels Erik, 2012, In: International Journal of Andrology. 35, 3, p. 449-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individual testosterone decline and future mortality risk in men
Holmboe, S. A., Skakkebæk, Niels Erik, Juul, Anders, Scheike, Thomas, Jensen, T. K., Linneberg, Allan René, Thuesen, B. H. & Andersson, A., Jan 2018, In: European Journal of Endocrinology. 178, p. 121-128Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects
Hansen, Lasse Bøllehuus, Kaludjerovic, J., Nielsen, J. E., Rehfeld, Anders Aagaard, Poulsen, N. N., Ide, N., Skakkebæk, Niels Erik, Frederiksen, H., Juul, Anders, Lanske, B. & Jensen, M. B., 2020, In: F A S E B Journal. 34, 9, p. 12436-12449Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of marital status on testosterone levels-A ten year follow-up of 1113 men
Holmboe, S. A., Priskorn, L., Jørgensen, N., Skakkebæk, Niels Erik, Linneberg, Allan René, Juul, Anders & Andersson, A., 2017, In: Psychoneuroendocrinology. 80, p. 155-161 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls
Chellakooty, M., Schmidt, I. M., Haavisto, A. M., Boisen, K. A., Damgaard, I. N., Mau, C., Petersen, Jørgen Holm, Juul, Anders, Skakkebæk, Niels Erik & Main, Katharina Maria, 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 8, p. 3515-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism
Bay, K., Virtanen, H. E., Hartung, S., Ivell, R., Main, Katharina Maria, Skakkebæk, Niels Erik, Andersson, A., Toppari, J. & Nordic Cryptorchidism Study Group, N. C. S. G., 1 Oct 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 4020-7 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Insulin-like factor 3 levels in second-trimester amniotic fluid
Bay, K., Cohen, A. S., Jørgensen, Finn Stener, Jørgensen, C., Lind, A. M., Skakkebæk, Niels Erik & Andersson, A., 1 Oct 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4048-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like growth factor I (IGF-I) and IGF-binding protein 3 as diagnostic markers of growth hormone deficiency in infancy
Jensen, R. B., Jeppesen, K. A., Vielwerth, S., Michaelsen, K. F., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Hormone Research. 63, 1, p. 15-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intranasal LH-RH treatment of cryptorchidism. A clinical trial and 5 years follow-up
Thorup, Jørgen Mogens, Mauritzen, K. & Skakkebæk, Niels Erik, 1987, In: European Journal of Pediatrics. 146 Suppl 2, p. S40-1Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intranasalt gonadotropinfrigørende hormon (LH-RH) som behandling ved retentio testis
Bertelsen, A., Skakkebæk, Niels Erik, Mauritzen, K., Preuss, P., Pedersen, P. V. & Thorup, Jørgen Mogens, 15 Jun 1981, In: Ugeskrift for Laeger. 143, 25, p. 1595-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat
Kristensen, D. M., Hass, U., Lesné, L., Lottrup, G., Jacobsen, P. R., Desdoits-Lethimonier, C., Boberg, J., Petersen, Jørgen Holm, Toppari, J., Jensen, T. K., Brunak, Søren, Skakkebæk, Niels Erik, Nellemann, C., Main, Katharina Maria, Jégou, B. & Leffers, H., 2011, In: Human Reproduction. 26, 1, p. 235-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: does insulin-like growth factor-I play a role?
Jensen, R. B. B., Chellakooty, M., Vielwerth, S., Vaag, Allan, Larsen, T. K., Greisen, Gorm, Skakkebæk, Niels Erik, Scheike, T. H. & Juul, Anders, 2003, In: Hormone Research. 60 Suppl 3, p. 136-48 13 p.Research output: Contribution to journal › Journal article › Research
- Published
In vitro bioassay investigations of the endocrine disrupting potential of steviol glycosides and their metabolite steviol, components of the natural sweetener Stevia
Shannon, M., Rehfeld, Anders Aagaard, Frizzell, C., Livingstone, C., McGonagle, C., Skakkebæk, Niels Erik, Wielogórska, E. & Connolly, L., 15 May 2016, In: Molecular and Cellular Endocrinology. 427, p. 65-72Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is Sedentary Lifestyle Associated With Testicular Function? A Cross-Sectional Study of 1,210 Men
Priskorn, L., Jensen, T. K., Bang, A. K., Nordkap, L., Joensen, Ulla Nordström, Lassen, T. H., Olesen, I. A., Swan, S. H., Skakkebæk, Niels Erik & Jørgensen, N., 15 Aug 2016, In: American Journal of Epidemiology. 184, 4, p. 284-294 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is human fecundity changing? A discussion of research and data gaps precluding us from having an answer
Smarr, M. M., Sapra, K. J., Gemmill, A., Kahn, L. G., Wise, L. A., Lynch, C. D., Factor-Litvak, P., Mumford, S. L., Skakkebæk, Niels Erik, Slama, R., Lobdell, D. T., Stanford, J. B., Jensen, T. K., Boyle, E. H., Eisenberg, M. L., Turek, P. J., Sundaram, R., Thoma, M. E. & Buck Louis, G. M., 2017, In: Human Reproduction. 32, 3, p. 499-504Research output: Contribution to journal › Comment/debate › Research
- Published
Is human fecundity declining?
Skakkebæk, Niels Erik, Jørgensen, N., Main, Katharina Maria, Rajpert-De Meyts, E., Leffers, H., Andersson, A., Juul, Anders, Carlsen, E., Mortensen, G. K., Jensen, T. K. & Toppari, J., 1 Feb 2006, In: International Journal of Andrology. 29, 1, p. 2-11 10 p.Research output: Contribution to journal › Journal article › Research
- Published
Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?
Bang, A. K., Busch, A. S., Almstrup, Kristian, Gromoll, J., Kliesch, S., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders, Tüttelmann, F. & Jørgensen, N., 2018, In: Andrology. 6, 1, p. 176-183 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is there a problem with male reproduction?
Joensen, Ulla Nordström, Skakkebæk, Niels Erik & Jørgensen, N., 2009, In: Nature Clinical Practice Endocrinology & Metabolism. 5, 3, p. 144-5 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity
Belling, K., Russo, F., Jensen, A. B., Dalgaard, M. D., Westergaard, D., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders & Brunak, Søren, 1 Apr 2017, In: Human Molecular Genetics. 26, 7, p. 1219-1229 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Klinefelter syndrome: the forgotten syndrome: basic and clinical questions posed to an international group of scientists
Juul, Anders, Aksglaede, L., Bay, K., Grigor, K. M. & Skakkebæk, Niels Erik, 1 Jun 2011, In: Acta Paediatrica. 100, 6, p. 791-2 2 p.Research output: Contribution to journal › Conference article › Research
- Published
Lack of stimulation of 24-hour growth hormone release by hypocaloric diet in obesity
Rasmussen, M. H., Juul, Anders, Kjems, L. L., Skakkebæk, Niels Erik & Hilsted, J., 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 3, p. 796-801 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35319116
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
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Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
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