Christina Engel Høi-Hansen

Christina Engel Høi-Hansen

Clinical Professor


  1. 2024
  2. Published

    Acetaminophen treatment in children and adults with spinal muscular atrophy: a lower tolerance and higher risk of hepatotoxicity

    Naume, Marie Mostue, Zhao, Q., Haslund-Krog, S. S., Krag, T., Winter, B. C. M. D., Revsbech, K. L., Vissing, John, Holst, H., Møller, Morten Hylander, Hornsyld, T. M., Dunø, M., Høi-Hansen, Christina Engel, Born, A. P., Bo Jensen, P. & Cathrine Ørngreen, M., 2024, In: Neuromuscular Disorders. 34, p. 9-18 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Assessment of fetal growth trajectory identifies infants at high risk of perinatal mortality

    Larsen, M. L., Krebs, Lone, Høi-Hansen, Christina Engel & Kumar, S., 2024, (E-pub ahead of print) In: Ultrasound in Obstetrics & Gynecology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Current state of hemispherectomy and callosotomy for pediatric refractory epilepsy in Denmark

    de Knegt, Victoria Elizabeth, Børresen, M. L., Knudsen, M., Thomsen, K. M., Uldall, P. V., Jakobsen, A. V. & Høi-Hansen, Christina Engel, 2024, In: Brain and Development. 46, 3, p. 142-148 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Impact of a National Follow-Up Program on the Age at Diagnosis for Cerebral Palsy

    Fabricius, R. A., Larsen, M. L., Debes, Nanette M Monique Mol, Rackauskaite, G. & Høi-Hansen, Christina Engel, 2024, In: Pediatric Neurology. 152, p. 56-61 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Mortality patterns in a Danish nationwide cohort of persons with intellectual disabilities

    Thygesen, L. C., Lassen, T. H., Horsbøl, T. A., Mairey, I. P., Juel, K., Høi-Hansen, Christina Engel & Michelsen, S. I., 2024, In: Journal of Intellectual Disabilities. 28, 2, p. 359-371 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Accepted/In press

    The diagnosis of cerebral palsy in two Danish national registries: a validation study

    Larsen, M. L., Høi-Hansen, Christina Engel & Rackauskaite, G., 2024, (Accepted/In press) In: Scandinavian Journal of Public Health. 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2023
  9. Published

    ATP6V0C variants impair V-ATPase function causing a neurodevelopmental disorder often associated with epilepsy

    Genomics England Research Consortium, G. E. R. C., 2023, In: Brain : a journal of neurology. 146, 4, p. 1357-1372 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Acute triage of childhood stroke in Denmark

    Bindslev, J. B., Hansen, Klaus, Laugesen, N. G., Benndorf, G., Høi-Hansen, Christina Engel & Truelsen, Thomas Clement, 2023, In: European Stroke Journal. 8, 2, p. 483–491 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Breast Cancer Screening Among Women With Intellectual Disability in Denmark

    Horsbøl, T. A., Michelsen, S. I., Lassen, T. H., Juel, K., Bigaard, J., Høi-Hansen, Christina Engel, Vejborg, I. & Thygesen, L. C., 2023, In: JAMA network open. 6, 1, 12 p., e2248980.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cerebral Palsy – Early Diagnosis and Intervention Trial: protocol for the prospective multicentre CP-EDIT study with focus on diagnosis, prognostic factors, and intervention

    Hoei-Hansen, C. E., Weber, L., Johansen, M., Fabricius, R., Hansen, J. K., Viuff, A. C. F., Rønde, G., Hahn, G. H., Østergaard, E., Duno, M., Larsen, V. A., Madsen, C. G., Røhder, K., Elvrum, A. K. G., Laugesen, B., Ganz, M., Madsen, K. S., Willerslev-Olsen, M., Debes, N. M., Christensen, J. & 2 others, Christensen, R. & Rackauskaite, G., 2023, In: BMC Pediatrics. 23, 1, 14 p., 544.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Children in Denmark with cerebral palsy rarely complete elementary school

    Pedersen, S. V., Wiingreen, R., Hansen, Bo Mølholm, Greisen, Gorm, Larsen, M. L. & Høi-Hansen, Christina Engel, 2023, In: Developmental Medicine and Child Neurology. 65, 10, p. 1387-1394 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effectiveness and safety of everolimus treatment in patients with tuberous sclerosis complex in real-world clinical practice

    Cockerell, I., Christensen, J., Høi-Hansen, Christina Engel, Holst, L., Grenaa Frederiksen, M., Issa-Epe, A. I., Nedregaard, B., Solhoff, R., Heimdal, K., Johannessen Landmark, C., Lund, C. & Nærland, T., 2023, In: Orphanet Journal of Rare Diseases. 18, 1, 14 p., 377.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Low skeletal muscle mass and liver fibrosis in children with cerebral palsy

    Naume, Marie Mostue, Jørgensen, M. H., Høi-Hansen, Christina Engel, Nielsen, M. R., Born, A. P., Vissing, John, Borgwardt, L., Stærk, D. M. R. & Ørngreen, M. C., 2023, In: European Journal of Pediatrics. 182, 11, p. 5047-5055 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Metabolic assessment in children with neuromuscular disorders shows risk of liver enlargement, steatosis and fibrosis

    Naume, Marie Mostue, Jørgensen, M. H., Høi-Hansen, Christina Engel, Born, A. P., Vissing, John, Borgwardt, L., Stærk, D. M. R. & Ørngreen, M. C., 2023, In: Acta Paediatrica, International Journal of Paediatrics. 112, 4, p. 846-853

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Predictive Value of Pediatric Stroke Diagnoses in Administrative Data: A Systematic Literature Review

    Bindslev, J. B., Ciochon, U. M., Hansen, Klaus, Høi-Hansen, Christina Engel & Truelsen, Thomas Clement, 2023, In: Neuroepidemiology. 56, 6, p. 413-422 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Severe Congenital Heart Defects and Cerebral Palsy

    Garne, E., Goldsmith, S., Barisic, I., Braz, P., Dakovic, I., Gibson, C., Hansen, M., Høi-Hansen, Christina Engel, Hollung, S. J., Klungsøyr, K., Smithers-Sheedy, H., Virella, D., Badawi, N., Watson, L. & McIntyre, S., 2023, In: Journal of Pediatrics. 262, 8 p., 113617.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Positive Predictive Value of Pediatric Stroke Diagnoses in Administrative Data: A Retrospective Validation Study

    Bindslev, J. B., Johnsen, S. P., Hansen, Klaus, Valentin, J. B., Høi-Hansen, Christina Engel & Truelsen, Thomas Clement, 2023, In: Clinical Epidemiology. 15, p. 755-764 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The magnitude rather than the rate of decline in fetal growth is a stronger risk factor for perinatal mortality in term infants

    Larsen, M. L., Schreiber, V., Krebs, Lone, Høi-Hansen, Christina Engel & Kumar, S., 2023, In: American journal of obstetrics & gynecology MFM. 5, 2, 100780.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2022
  22. Published

    Basal og avanceret behandling af børn og voksne med epilepsi

    Høi-Hansen, Christina Engel, Tinggaard, J., Kløvgaard, M. & Sabers, A., 2022, In: Ugeskrift for Laeger. 184, 26, V01220072.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Causes and Risk Factors of Pediatric Spontaneous Intracranial Hemorrhage — A Systematic Review

    Ciochon, U. M., Bindslev, J. B. B., Høi-Hansen, Christina Engel, Truelsen, Thomas Clement, Larsen, V. A., Nielsen, Michael Bachmann & Hansen, Adam Espe, 2022, In: Diagnostics. 12, 6, 12 p., 1459.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Declining prevalence of cerebral palsy in children born at term in Denmark

    Larsen, M. L., Rackauskaite, G., Greisen, Gorm, Laursen, B., Uldall, P., Krebs, Lone & Høi-Hansen, Christina Engel, 2022, In: Developmental Medicine and Child Neurology. 64, 6, p. 715-722

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Deep Molecular Characterization of Milder Spinal Muscular Atrophy Patients Carrying the c.859G>C Variant in SMN2

    Blasco-Pérez, L., Costa-Roger, M., Leno-Colorado, J., Bernal, S., Alias, L., Codina-Solà, M., Martínez-Cruz, D., Castiglioni, C., Bertini, E., Travaglini, L., Millán, J. M., Aller, E., Sotoca, J., Juntas, R., Hoei-Hansen, C. E., Moreno-Escribano, A., Guillén-Navarro, E., Costa-Comellas, L., Munell, F., Boronat, S. & 4 others, Rojas-García, R., Povedano, M., Cuscó, I. & Tizzano, E. F., 2022, In: International Journal of Molecular Sciences. 23, 15, 8289.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Early postoperative complications were common in non-ambulant paediatric patients with neuromuscular scoliosis

    Naume, Marie Mostue, Møller, Morten Hylander, Høi-Hansen, Christina Engel, Born, A. P., Brekke, G., Andersen, Thomas Borbjerg, Dirks, J. & Ørngreen, M. C., 2022, In: Acta Paediatrica, International Journal of Paediatrics. 111, 3, p. 593-594 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    First-trimester biomarkers and the risk of cerebral palsy

    Larsen, M. L., Rackauskaite, G., Pihl, K., Uldall, P., Greisen, Gorm, Krebs, Lone & Høi-Hansen, Christina Engel, 2022, In: Early Human Development. 167, 105564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Genotype-phenotype correlations in SCN8A-related disorders reveal prognostic and therapeutic implications

    Johannesen, K. M., Liu, Y., Koko, M., Gjerulfsen, C. E., Sonnenberg, L., Schubert, J., Fenger, C. D., Eltokhi, A., Rannap, M., Koch, N. A., Lauxmann, S., Krüger, J., Kegele, J., Canafoglia, L., Franceschetti, S., Mayer, T., Rebstock, J., Zacher, P., Ruf, S., Alber, M. & 109 others, Sterbova, K., Lassuthová, P., Vlckova, M., Lemke, J. R., Platzer, K., Krey, I., Heine, C., Wieczorek, D., Kroell-Seger, J., Lund, C., Klein, K. M., Au, P. Y. B., Rho, J. M., Ho, A. W., Masnada, S., Veggiotti, P., Giordano, L., Accorsi, P., Høi-Hansen, Christina Engel, Striano, P., Zara, F., Verhelst, H., Verhoeven, J. S., Braakman, H. M. H., van der Zwaag, B., Harder, A. V. E., Brilstra, E., Pendziwiat, M., Lebon, S., Vaccarezza, M., Le, N. M., Christensen, J., Grønborg, S., Scherer, S. W., Howe, J., Fazeli, W., Howell, K. B., Leventer, R., Stutterd, C., Walsh, S., Gerard, M., Gerard, B., Matricardi, S., Bonardi, C. M., Sartori, S., Berger, A., Hoffman-Zacharska, D., Mastrangelo, M., Darra, F., Vøllo, A., Motazacker, M. M., Lakeman, P., Nizon, M., Betzler, C., Altuzarra, C., Caume, R., Roubertie, A., Gélisse, P., Marini, C., Guerrini, R., Bilan, F., Tibussek, D., Koch-Hogrebe, M., Perry, M. S., Ichikawa, S., Dadali, E., Sharkov, A., Mishina, I., Abramov, M., Kanivets, I., Korostelev, S., Kutsev, S., Wain, K. E., Eisenhauer, N., Wagner, M., Savatt, J. M., Müller-Schlüter, K., Bassan, H., Borovikov, A., Nassogne, M. C., Destrée, A., Schoonjans, A. S., Meuwissen, M., Buzatu, M., Jansen, A., Scalais, E., Srivastava, S., Tan, W. H., Olson, H. E., Loddenkemper, T., Poduri, A., Helbig, K. L., Helbig, I., Fitzgerald, M. P., Goldberg, E. M., Roser, T., Borggraefe, I., Brünger, T., May, P., Lal, D., Lederer, D., Rubboli, Guido, Heyne, H. O., Lesca, G., Hedrich, U. B. S., Benda, J., Gardella, E., Lerche, H. & Møller, R. S., 2022, In: Brain. 145, 9, p. 2991-3009 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Nutrition and preparation of blenderized tube feeding in children and adolescents with neurological impairment: A scoping review

    Brekke, G., Raun, A. M. T., Sørensen, S. B., Kok, K., Sorensen, Jette Led , Born, A. P., Mølgaard, Christian & Høi-Hansen, Christina Engel, 2022, In: Nutrition in Clinical Practice. 37, 4, p. 783-796 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    The effect of gestational age on major neurodevelopmental disorders in preterm infants

    Larsen, M. L., Wiingreen, R., Jensen, A., Rackauskaite, G., Laursen, B., Hansen, Bo Mølholm, Høi-Hansen, Christina Engel & Greisen, Gorm, 2022, In: Pediatric Research. 91, p. 1906–1912

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy

    Lorentzen, Jakob, Born, A. P., Svane, Christian, Forman, C., Laursen, B., Langkilde, Annika Reynberg, Uldall, P. & Høi-Hansen, Christina Engel, 2022, In: Acta Paediatrica, International Journal of Paediatrics. 111, 2, p. 323-335 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2021
  33. Published

    Børn med iskæmisk apopleksi

    Bindslev, J. B., Truelsen, Thomas Clement, Gyhrs, M., Kondziella, Daniel, Hoffmann, M., Stensballe, J., Hauerberg, J., Stavngaard, T., Lundstrøm, K., Born, A. P., Larsen, V. A., Hansen, Klaus & Høi-Hansen, Christina Engel, 14 Jun 2021, In: Ugeskrift for Laeger. 183, 24, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Combined Muscle Biopsy and Comprehensive Electrophysiology in General Anesthesia is Valuable in Diagnosis of Neuromuscular Disease in Children

    Høi-Hansen, Christina Engel, Tygesen, M. L. B., Dunø, M., Vissing, John, Ballegaard, Martin & Born, P., 2021, In: Neuropediatrics. 52, 6, p. 462-468

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Fatal case of hospital-acquired hypernatraemia in a neonate: lessons learned from a tragic error

    Overgaard-steensen, C., Poorisrisak, P., Heiring, C., Schmidt, Lisbeth Samsø, Voldby, A., Høi-Hansen, Christina Engel, Langkilde, Annika Reynberg & Sterns, R. H., 2021, In: Clinical Kidney Journal. 14, 4, p. 1277-1283

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Nutritional screening of children and adolescents with cerebral palsy: a scoping review

    Sørensen, S. J., Brekke, G., Kok, K., Sorensen, Jette Led , Born, A. P., Mølgaard, Christian & Høi-Hansen, Christina Engel, 2021, In: Developmental Medicine and Child Neurology. 63, 12, p. 1374-1381 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Prolonged fasting-induced hyperketosis, hypoglycaemia and impaired fat oxidation in child and adult patients with spinal muscular atrophy type II

    Orngreen, M. C., Andersen, A. G., Eisum, A., Hald, E. J., Raaschou-Pedersen, D. E., Lokken, N., Høi-Hansen, Christina Engel, Vissing, John, Born, A. P. & van Hall, Gerrit, 2021, In: Acta Paediatrica. 110, 12, p. 3367-3375 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The braindrugs-epilepsy cohort - precision medicine in the treatment of epilepsy

    Marstrand-Joergensen, M. R., Dam, V. N. H., Vinter, K., Andersen, N. B., Ip, C. T., Høi-Hansen, Christina Engel, Born, A. P., Ozenne, Brice Maxime Hugues, Ganz, Melanie, Jørgensen, Martin Balslev, Hansen, Adam Espe, Beniczky, S., Frøkjær, Vibe Gedsø, Fisher, P. M., Ryvlin, P., Knudsen, Gitte Moos & Pinborg, Lars Hageman, 2021, In: European Neuropsychopharmacology. 53, p. S39-S40 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  39. 2020
  40. Published

    Increase in cognitive function is seen in many single-operated pediatric patients after epilepsy surgery

    de Knegt, V. E., Høi-Hansen, Christina Engel, Knudsen, M., Jakobsen, A. V., Mûller, E., Thomsen, K. M., Jespersen, B., Uldall, P. V. & Børresen, M. L., 2020, In: Seizure. 81, p. 254-262 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Infantile spasmer

    Préel, M., Møller, R. S., Miranda, Maria J. & Høi-Hansen, Christina Engel, 2020, In: Ugeskrift for Laeger. 182, 15, 8 p., V10190597.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Mowat-Wilson syndrome: growth charts

    Ivanovski, I., Djuric, O., Broccoli, S., Caraffi, S. G., Accorsi, P., Adam, M. P., Avela, K., Badura-Stronka, M., Bayat, A., Clayton-Smith, J., Cocco, I., Cordelli, D. M., Cuturilo, G., Di Pisa, V., Dupont Garcia, J., Gastaldi, R., Giordano, L., Guala, A., Hoei-Hansen, C., Inaba, M. & 33 others, Iodice, A., Nielsen, Jens Erik Klint, Kuburovic, V., Lazalde-Medina, B., Malbora, B., Mizuno, S., Moldovan, O., Møller, R. S., Muschke, P., Otelli, V., Pantaleoni, C., Piscopo, C., Poch-Olive, M. L., Prpic, I., Marín Reina, P., Raviglione, F., Ricci, E., Scarano, E., Simonte, G., Smigiel, R., Tanteles, G., Tarani, L., Trimouille, A., Valera, E. T., Schrier Vergano, S., Writzl, K., Callewaert, B., Savasta, S., Street, M. E., Iughetti, L., Bernasconi, S., Giorgi Rossi, P. & Garavelli, L., 2020, In: Orphanet Journal of Rare Diseases. 15, 12 p., 151.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2009
  44. Published
  45. 2007
  46. Published

    Origin of testicular germ cell neoplasia: The role of sex chromosomes

    Rajpert-De Meyts, E., Ottesen, A. M., Høi-Hansen, Christina Engel, Sonne, Si Brask, Leffers, H. & Skakkebæk, Niels Erik, 1 Jan 2007, The Y Chromosome and Male Germ Cell Biology in Health and Diseases. World Scientific Publishing Co., p. 289-308 20 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  47. 2005
  48. Published

    Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours

    Almstrup, Kristian, Høi-Hansen, Christina Engel, Nielsen, J. E., Wirkner, U., Ansorge, W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 23 May 2005, In: British Journal of Cancer. 92, 10, p. 1934-1941 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2γ in semen samples: Case report

    Høi-Hansen, Christina Engel, Rajpert-De Meyts, E., Carlsen, E., Almstrup, Kristian, Leffers, H. & Skakkebæk, Niels Erik, Mar 2005, In: Human Reproduction. 20, 3, p. 579-582 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2004
  51. Published

    Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling

    Almstrup, Kristian, Høi-Hansen, Christina Engel, Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jul 2004, In: Cancer Research. 64, 14, p. 4736-4743 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Identification of genes differentially expressed in testes containing carcinoma in situ

    Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-DeMeyts, E. & Leffers, H., Jun 2004, In: Molecular Human Reproduction. 10, 6, p. 423-431 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Transcription factor AP-2γ is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors

    Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2004, In: Clinical Cancer Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 50967810