Klaus Bønnelykke

Distinct immune phenotypes in infants developing asthma during childhood

Thysen, A. H., Waage, J., Larsen, J. M., Rasmussen, Morten Arendt, Stokholm, Jakob, Chawes, Bo Lund Krogsgaard, Fink, N. R., Pedersen, T. M., Wolsk, H., Thorsteinsdottir, S., Litman, T., Renz, H., Bønnelykke, Klaus, Bisgaard, H. & Brix, S., 2020, In: Science Translational Medicine. 12, 529, 13 p., eaaw0258.

Research output: Contribution to journal › Journal article › Research › peer-review

Early life bacterial airway colonization, local immune mediator response and risk of otitis media

Christensen, E. D., Thorsen, Jonathan Jan Ilve, Stokholm, Jakob, Pedersen, T. M., Brix, S., Krogfelt, K. A., Schjørring, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Bisgaard, H. & Rasmussen, Morten Arendt, 2020, In: Journal of Medical Microbiology. 69, 8, p. 1124–1131 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of High-Dose vs Standard-Dose Vitamin D Supplementation in Pregnancy on Bone Mineralization in Offspring Until Age 6 Years: A Prespecified Secondary Analysis of a Double-Blinded, Randomized Clinical Trial

Brustad, N., Garland, J., Thorsen, Jonathan Jan Ilve, Sevelsted, A., Krakauer, M., Vinding, R. K., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2020, In: JAMA Pediatrics. 174, 5, p. 419-427 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age

Morin, A., McKennan, C. G., Pedersen, C. T., Stokholm, Jakob, Chawes, Bo Lund Krogsgaard, Schoos, A. M., Naughton, K. A., Thorsen, Jonathan Jan Ilve, Mortensen, M. S., Vercelli, D., Trivedi, Urvish, Sørensen, Søren Johannes, Bisgaard, H., Nicolae, D. L., Bønnelykke, Klaus & Ober, C., 2020, In: Journal of Allergy and Clinical Immunology. 146, 6, p. 1358-1366

Research output: Contribution to journal › Journal article › Research › peer-review

High-Dose Vitamin D Supplementation in Pregnancy and Neurodevelopment in Childhood: A Prespecified Secondary Analysis of a Randomized Clinical Trial

Sass, L., Vinding, R. K., Stokholm, Jakob, Bjarnadóttir, Elín, Noergaard, S., Thorsen, J., Sunde, R. B., McGrath, J., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard & Bisgaard, H., 2020, In: JAMA Network Open. 3, 12, 14 p., e2026018.

Research output: Contribution to journal › Journal article › Research › peer-review

Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

Thyssen, J. P., Ahluwalia, T. S., Paternoster, L., Ballardini, N., Bergström, A., Melén, E., Chawes, B. L., Stokholm, J., Hourihane, J. O. B., O'Sullivan, D. M., Bager, P., Melbye, M., Bustamante, M., Torrent, M., Esplugues, A., Duijts, L., Hu, C., Elbert, N. J., Pasmans, S. G. M. A., Nijsten, T. E. C. & 16 others, von Berg, A., Standl, M., Schikowski, T., Herberth, G., Heinrich, J., Lee, Y. A., Marenholz, I., Lau, S., Curtin, J. A., Simpson, A., Custovic, A., Pennell, C. E., Wang, C. A., Holt, P. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Allergy: European Journal of Allergy and Clinical Immunology. 75, 6, p. 1481-1485

Research output: Contribution to journal › Letter › Research › peer-review

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

Zheng, Y., Huang, T., Wang, T., Mei, Z., Sun, Z., Zhang, T., Ellervik, C., Chai, J-F., Sim, X., van Dam, R. M., Tai, E-S., Koh, W-P., Dorajoo, R., Saw, S-M., Sabanayagam, C., Wong, T. Y., Gupta, P., Rossing, P., Ahluwalia, T. S., Vinding, R. K. & 98 others, Bisgaard, H., Bønnelykke, Klaus, Wang, Y., Graff, M., Voortman, T., van Rooij, F. J. A., Hofman, A., van Heemst, D., Noordam, R., Estampador, A. C., V Varga, Tibor, Enzenbach, C., Scholz, M., Thiery, J., Burkhardt, R., Orho-Melander, M., Schulz, C., Ericson, U., Sonestedt, E., Kubo, M., Akiyama, M., Zhou, A., Kilpeläinen, Tuomas O., Hansen, Torben, Kleber, M. E., Delgado, G., McCarthy, M., Lemaitre, R. N., Felix, J. F., Jaddoe, V. W. V., Wu, Y., Mohlke, K. L., Lehtimäki, T., Wang, C. A., Pennell, C. E., Schunkert, H., Kessler, T., Zeng, L., Willenborg, C., Peters, A., Lieb, W., Grote, V., Rzehak, P., Koletzko, B., Erdmann, J., Munz, M., Wu, T., He, M., Yu, C., Lecoeur, C., Froguel, P., Corella, D., Moreno, L. A., Lai, C., Pitkänen, N., Boreham, C. A., Ridker, P. M., Rosendaal, F. R., de Mutsert, R., Power, C., Paternoster, L., Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Djousse, L., Rivadeneira, F., Lee, N. R., Raitakari, O. T., Kähönen, M., Viikari, J., Langhendries, J., Escribano, J., Verduci, E., Dedoussis, G., König, I., Balkau, B., Coltell, O., Dallongeville, J., Meirhaeghe, A., Amouyel, P., Gottrand, F., Pahkala, K., Niinikoski, H., Hyppönen, E., März, W., Mackey, D. A., Gruszfeld, D., Tucker, K. L., Fumeron, F., Estruch, R., Ordovas, J. M., Arnett, D. K., Mook-Kanamori, D. O., Mozaffarian, D., Psaty, B. M., North, K. E., Chasman, D. I. & Qi, L., 2020, In: European Journal of Epidemiology. 35, p. 685–697 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Vogelezang, S., Bradfield, J. P., Ahluwalia, Tarun Veer Singh, Curtin, J. A., Grarup, Niels, Schnurr, T. M., Hansen, Torben, Michaelsen, Kim F., Pedersen, Oluf Borbye, Stokholm, Jakob, Lind, M. V., Frithioff-Bøjsøe, C., Holm, Jens-Christian, Felix, J. F. & Early Growth Genetics Consortium, E. G. G. C., 2020, In: P L o S Genetics. 16, 10, 26 p., e1008718.

Research output: Contribution to journal › Journal article › Research › peer-review

Parent-specific effects on risk of developing allergic sensitization and asthma in childhood

Schoos, A. M., Hansen, B. R., Stokholm, Jakob, Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus & Bisgaard, H., 2020, In: Clinical and Experimental Allergy. 50, 8, p. 915-921

Research output: Contribution to journal › Journal article › Research › peer-review

Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation

King, C., McKenna, A., Farzan, N., Vijverberg, S. J., van der Schee, M. P., Maitland-van der Zee, A. H., Arianto, L., Bisgaard, H., BØnnelykke, K., Berce, V., Potočnik, U., Repnik, K., Carleton, B., Daley, D., Chew, F. T., Chiang, W. C., Sio, Y. Y., Cloutier, M. M., Den Dekker, H. T., Duijts, L. & 16 others, de Jongste, J. C., Dijk, F. N., Koppelman, G. H., Flores, C., Hernandez-Pacheco, N., Pino-Yanes, M., Mukhopadhyay, S., Basu, K., Bignell, L., Tantisira, K. G., Turner, S., Verhamme, K. M., Francis, B., Pirmohamed, M., Sinha, I. & Hawcutt, D. B., 2020, In: The Pharmacogenomics Journal. 20, p. 621–628 8 p.

Research output: Contribution to journal › Review › Research › peer-review

Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial

Hjelmsø, M. H., Shah, S. A., Thorsen, Jonathan Jan Ilve, Rasmussen, Morten Arendt, Vestergaard, G., Mortensen, M. S., Brejnrod, A., Brix, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes, Stokholm, Jakob & Bisgaard, H., 2020, In: Nature Communications. 11, 10 p., 426.

Research output: Contribution to journal › Journal article › Research › peer-review

Role of viruses in asthma

Jartti, T., Bønnelykke, Klaus, Elenius, V. & Feleszko, W., 2020, In: Seminars in Immunopathology. 42, 1, p. 61-74 14 p.

Research output: Contribution to journal › Review › Research › peer-review

Vitamin D Supplement during Pregnancy and Enamel Defects in Offspring - Reply

Nørrisgaard, P. E., Bønnelykke, Klaus & Bisgaard, H., 2020, In: JAMA Pediatrics. 174, 3, p. 304-305 2 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A., Rossi, R. M. & 54 others, Skogstrand, K., Peng, S., Thompson, W. K., Appadurai, V., Lawlor, D. A., Kalliala, I., Power, C., McCarthy, M. I., Boyd, H. A., Marazita, M. L., Hakonarson, H., Hayes, M. G., Scholtens, D. M., Rivadeneira, F., Jaddoe, V. W. V., Vinding, R. K., Bisgaard, H., Knight, B. A., Pahkala, K., Raitakari, O., Helgeland, Ø., Johansson, S., Njølstad, P. R., Fadista, J., Schork, A. J., Nudel, R., Miller, D. E., Chen, X., Weirauch, M. T., Mortensen, P. B., Børglum, A. D., Nordentoft, Merete, Mors, O., Hao, K., Ryckman, K. K., Hougaard, D. M., Kottyan, L. C., Pennell, C. E., Lyytikainen, L., Bønnelykke, Klaus, Vrijheid, M., Felix, J. F., Lowe, W. L., Grant, S. F. A., Hyppönen, E., Jacobsson, B., Jarvelin, M., Muglia, L. J., Murray, J. C., Freathy, R. M., Werge, Thomas, Melbye, M., Buil, A. & Feenstra, B., 2 Sep 2019, In: Nature Communications. 10, 1, 13 p., 3927.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring: A 6-Year Follow-up of a Randomized Clinical Trial

Nørrisgaard, P. E., Haubek, D., Kühnisch, J., Chawes, Bo Lund Krogsgaard, Stokholm, Jakob, Bønnelykke, Klaus & Bisgaard, H., 5 Aug 2019, In: JAMA Pediatrics. 173, 10, p. 924-930 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Bronchiolitis needs a revisit: Distinguishing between virus entities and their treatments

Jartti, T., Smits, H. H., Bønnelykke, Klaus, Bircan, O., Elenius, V., Konradsen, J. R., Maggina, P., Makrinioti, H., Stokholm, Jakob, Hedlin, G., Papadopoulos, N., Ruszczynski, M., Ryczaj, K., Schaub, B., Schwarze, J., Skevaki, C., Stenberg-Hammar, K., Feleszko, W. & EAACI Task Force on Clinical Practice Recommendations on Preschool Wheeze, E. T. F. O. C. P. R. O. P. W., Jan 2019, In: Allergy. 74, 1, p. 40-52 13 p.

Research output: Contribution to journal › Review › Research › peer-review

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

Bradfield, J. P., Vogelezang, S., Felix, J. F., Chesi, A., Helgeland, O., Horikoshi, M., Karhunen, V., Lowry, E., Cousminer, D. L., Ahluwalia, T. S., Thiering, E., Boh, E. T-H., Zafarmand, M. H., Vilor-Tejedor, N., Wang, C. A., Joro, R., Chen, Z., Gauderman, W. J., Pitkanen, N., Parra, E. J. & 79 others, Fernandez-Rhodes, L., Alyass, A., Monnereau, C., Curtin, J. A., Have, C. T., McCormack, S. E., Hollensted, M., Frithioff-Bojsoe, C., Valladares-Salgado, A., Peralta-Romero, J., Teo, Y., Standl, M., Leinonen, J. T., Holm, Jens-Christian, Peters, T., Vioque, J., Vrijheid, M., Simpson, A., Custovic, A., Vaudel, M., Canouil, M., Lindi, V., Atalay, M., Kahonen, M., Raitakari, O. T., van Schaik, B. D. C., Berkowitz, R. I., Cole, S. A., Voruganti, V. S., Wang, Y., Highland, H. M., Comuzzie, A. G., Butte, N. F., Justice, A. E., Gahagan, S., Blanco, E., Lehtimaki, T., Lakka, T. A., Hebebrand, J., Bonnefond, A., Grarup, Niels, Froguel, P., Lyytikainen, L., Cruz, M., Kobes, S., Hanson, R. L., Zemel, B. S., Hinney, A., Teo, K. K., Meyre, D., North, K. E., Gilliland, F. D., Bisgaard, H., Bustamante, M., Bønnelykke, Klaus, Pennell, C. E., Rivadeneira, F., Uitterlinden, A. G., Baier, L. J., Vrijkotte, T. G. M., Heinrich, J., Sørensen, Thorkild I.A., Saw, S., Pedersen, Oluf Borbye, Hansen, Torben, Eriksson, J., Widen, E., McCarthy, M. I., Njolstad, P. R., Power, C., Hypponen, E., Sebert, S., Brown, C. D., Jarvelin, M., Timpson, N. J., Johansson, S., Hakonarson, H., Jaddoe, V. W. V. & Grant, S. F. A., 2019, In: Human Molecular Genetics. 28, 19, p. 3327-3338

Research output: Contribution to journal › Journal article › Research › peer-review

Airway obstruction and bronchial reactivity from age 1 month until 13 years in children with asthma: A prospective birth cohort study

Hallas, H. W., Chawes, Bo Lund Krogsgaard, Rasmussen, Morten Arendt, Arianto, L., Stokholm, Jakob, Bønnelykke, Klaus & Bisgaard, H., 2019, In: PLoS Medicine. 16, 1, 20 p., e1002722.

Research output: Contribution to journal › Journal article › Research › peer-review

Antibiotic exposure in infancy and development of BMI and body composition in childhood

Sejersen, T. S., Vinding, R. K., Stokholm, Jakob, Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Krakauer, M. & Bisgaard, H., 2019, In: EClinicalMedicine. 17, 7 p., 100209.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

Huang, T., Wang, T., Zheng, Y., Ellervik, C., Li, X., Gao, M., Fang, Z., Chai, J-F., Ahluwalia, T. V. S., Wang, Y., Voortman, T., Noordam, R., Frazier-Wood, A., Scholz, M., Sonestedt, E., Akiyama, M., Dorajoo, R., Zhou, A., Kilpeläinen, T. O., Kleber, M. E. & 31 others, Crozier, S. R., Godfrey, K. M., Lemaitre, R., Felix, J. F., Shi, Y., Gupta, P., Khor, C., Lehtimäki, T., Wang, C. A., Tiesler, C. M. T., Thiering, E., Standl, M., Rzehak, P., Marouli, E., He, M., Lecoeur, C., Corella, D., Lai, C., Moreno, L. A., Pitkänen, N., Boreham, C. A., Zhang, T., Hansen, Torben, Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Bisgaard, H., Pedersen, Oluf Borbye, Bønnelykke, Klaus, Rossing, Peter & BIRTH-GENE (BIG) Study Working Group, B. (. S. W. G., 2019, In: JAMA Network Open. 2, 9, 18 p., e1910915.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, Anna Elisabet, Justice, A. E., Kernson, N. D., Larson, N. B., Lin, K., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., drb459, drb459, Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, Oluf Borbye, Nohr, E. A., Newman, A. B., Linneberg, Allan René, Langenberg, C., Kilpeläinen, Tuomas O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, Thorkild I.A., Homuth, G., Hansen, Torben, Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. I., Chakravarti, A., Brandslund, I., Bønnelykke, Klaus, Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, Niels, Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, Ruth, Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., 2019, In: American Journal of Human Genetics. 104, 1, p. 112-138 27 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC₂₀₁₀ ) Mother-Child Cohort

Bjarnadóttir, E., Stokholm, Jakob, Chawes, Bo Lund Krogsgaard, Thorsen, Jonathan Jan Ilve, Mora-Jensen, A. R. C., Deleuran, M., Bønnelykke, Klaus, Lauritzen, Lotte & Bisgaard, H., 2019, In: Acta Paediatrica. 108, 9, p. 1632-1641 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

Hartwig, F. P., Davies, N. M., Horta, B. L., Ahluwalia, T. S., Bisgaard, H., Bønnelykke, K., Caspi, A., Moffitt, T. E., Poulton, R., Sajjad, A., Tiemeier, H. W., Dalmau-Bueno, A., Guxens, M., Bustamante, M., Santa-Marina, L., Parker, N., Paus, T., Pausova, Z., Lauritzen, L., Schnurr, T. M. & 7 others, Michaelsen, Kim F., Hansen, Torben, Oddy, W., Pennell, C. E., Warrington, N. M., Davey Smith, G. & Victora, C. G., 2019, In: International Journal of Epidemiology. 48, 1, p. 45-57 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Environmental and Genetic Determinants of Serum 25(OH)-Vitamin D Levels during Pregnancy and Early Childhood

Schoos, A. M., Vinther, C., Nørgaard, S., Brustad, N., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2019, In: Children. 6, 10, 15 p., 116.

Research output: Contribution to journal › Journal article › Research › peer-review

Fish Oil Supplementation in Pregnancy Increases Gestational Age, Size for Gestational Age, and Birth Weight in Infants: A Randomized Controlled Trial

Vinding, R. K., Stokholm, Jakob, Sevelsted, A., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Barman, M., Jacobsson, B. & Bisgaard, H., 2019, In: Journal of Nutrition. 149, 4, p. 628-634 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Fish-oil supplementation in pregnancy, child metabolomics and asthma risk

Rago, D., Rasmussen, Morten Arendt, Lee-Sarwar, K. A., Weiss, S. T., Lasky-Su, J., Stokholm, Jakob, Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard & Bisgaard, H., 2019, In: EBioMedicine. 46, p. 399-410 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

BIOS Consortium, B. C., Sebert, S., McCarthy, M. I., Järvelin, M. & Early Growth Genetics (EGG) Consortium, E. G. G. (. C., 2019, In: Science Advances. 5, 9, 18 p., eaaw3095.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic, Clinical, and Environmental Factors Associated With Persistent Atopic Dermatitis in Childhood

Thorsteinsdottir, S., Stokholm, Jakob, Thyssen, Jacob Pontoppidan, Nørgaard, S., Thorsen, Jonathan Jan Ilve, Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Waage, J. & Bisgaard, H., 2019, In: JAMA Dermatology. 155, 1, p. 50-57 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

High-Dose Vitamin D Supplementation During Pregnancy and Asthma in Offspring at the Age of 6 Years

Brustad, N., Eliasen, A. U., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2019, In: J A M A: The Journal of the American Medical Association. 321, 10, p. 1003-1005

Research output: Contribution to journal › Letter › Research › peer-review

Immune Mediator Levels in the Upper Airways Predict Response to Azithromycin for Episodes with Asthma-like Symptoms in Young Children

Carlsson, C. J., Rasmussen, Morten Arendt, Brix, S., Wang, N., Stokholm, J., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus & Bisgaard, H., 2019, In: Pediatric Pulmonology. 54, S1, p. S75-S76 2 p., A-27.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

Thorsen, Jonathan Jan Ilve, Rasmussen, Morten Arendt, Waage, J., Mortensen, M., Brejnrod, A., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard, Brix, S., Sørensen, Søren Johannes, Stokholm, Jakob & Bisgaard, H., 2019, In: Nature Communications. 10, 8 p., 5001.

Research output: Contribution to journal › Journal article › Research › peer-review

Levels of Systemic Low-grade Inflammation in Pregnant Mothers and Their Offspring are Correlated

Fink, N. R., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Thorsen, Jonathan Jan Ilve, Stokholm, Jakob, Rasmussen, Morten Arendt, Brix, Susanne & Bisgaard, H., 2019, In: Scientific Reports. 9, p. 1-9 3043.

Research output: Contribution to journal › Journal article › Research › peer-review

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

UK10K Consortium, U. C., Al Turki, S., Anderson, C. A., Anney, R., Zhang, F., Zhang, P. & Zheng, H., 2019, In: Nature Communications. 10, 16 p., 357.

Research output: Contribution to journal › Journal article › Research › peer-review

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Stokholm, Jakob, Michaelsen, Kim F., Freathy, R. M. & EGG Consortium, E. C., 2019, In: Nature Genetics. 51, 5, p. 804-814

Research output: Contribution to journal › Journal article › Research › peer-review

Multiple Breath Washout for Diagnosing Asthma and Persistent Wheeze in Young Children

Arianto, L., Hallas, H., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2019, In: American Thoracic Society. Annals (Print). 16, 5, p. 599-605 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Neonatal Urine Metabolic Profiling and Development of Childhood Asthma

Chawes, Bo Lund Krogsgaard, Giordano, G., Pirillo, P., Rago, D., Rasmussen, Morten Arendt, Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Baraldi, E., 2019, In: Metabolites. 9, 9, 16 p., 185.

Research output: Contribution to journal › Journal article › Research › peer-review

Reduced IL-2 response from peripheral blood mononuclear cells exposed to bacteria at 6 months of age is associated with elevated total-IgE and allergic rhinitis during the first 7 years of life

Wang, N., Schoos, A. M., Larsen, J. M., Brix, S., Thysen, A. H., Rasmussen, Morten Arendt, Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2019, In: EBioMedicine. 43, p. 587-593

Research output: Contribution to journal › Journal article › Research › peer-review

Sensitivity of multiple breath washout to detect mild-to-moderate asthma in adolescence

Arianto, L., Hallas, H. W., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2019, In: The Journal of Allergy and Clinical Immunology: In Practice. 7, 6, p. 2052-2054.e5

Research output: Contribution to journal › Letter › Research › peer-review

Single and multiple time-point allergic sensitization during childhood and risk of asthma by age 13

Schoos, A. M. M., Jelding-Dannemand, E., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H. & Chawes, Bo Lund Krogsgaard, 2019, In: Pediatric Allergy and Immunology. 30, 7, p. 716-723 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Middeldorp, C. M., Mahajan, A., Horikoshi, M., Robertson, N. R., Beaumont, R. N., Bradfield, J. P., Bustamante, M., Cousminer, D. L., Day, F. R., De Silva, N. M., Guxens, M., Mook-Kanamori, D. O., St Pourcain, B., Warrington, N. M., Adair, L. S., Ahlqvist, E., Ahluwalia, T. S., Almgren, P., Ang, W., Atalay, M. & 463 others, Auvinen, J., Bartels, M., Beckmann, J. S., Bilbao, J. R., Bond, T., Borja, J. B., Cavadino, A., Charoen, P., Chen, Z., Coin, L., Cooper, C., Curtin, J. A., Custovic, A., Das, S., Davies, G. E., Dedoussis, G. V., Duijts, L., Eastwood, P. R., Eliasen, A. U., Elliott, P., Eriksson, J. G., Estivill, X., Fadista, J., Fedko, I. O., Frayling, T. M., Gaillard, R., Gauderman, W. J., Geller, F., Gilliland, F., Gilsanz, V., Granell, R., Grarup, Niels, Groop, L., Hadley, D., Hakonarson, H., Hansen, Torben, Hartman, C. A., Hattersley, A. T., Hayes, M. G., Hebebrand, J., Heinrich, J., Helgeland, O., Henders, A. K., Henderson, J., Henriksen, T. B., Hirschhorn, J. N., Hivert, M., Hocher, B., Holloway, J. W., Holt, P., Hottenga, J., Hypponen, E., Iniguez, C., Johansson, S., Jugessur, A., Kahonen, M., Kalkwarf, H. J., Kaprio, J., Karhunen, V., Kemp, J. P., Kerkhof, M., Koppelman, G. H., Korner, A., Kotecha, S., Kreiner-Moller, E., Kulohoma, B., Kumar, A., Kutalik, Z., Lahti, J., Lappe, J. M., Larsson, H., Lehtimaki, T., Lewin, A. M., Li, J., Lichtenstein, P., Lindgren, C. M., Lindi, V., Linneberg, Allan René, Liu, X., Liu, J., Lowe, W. L. ,. J., Lundstrom, S., Lyytikainen, L., Ma, R. C. W., Mace, A., Magi, R., Magnus, P., Mamun, A. A., Mannikko, M., Martin, N. G., Mbarek, H., McCarthy, N. S., Medland, S. E., Melbye, M., Melen, E., Mohlke, K. L., Monnereau, C., Morgen, C. S., Morris, A. P., Murray, J. C., Myhre, R., Najman, J. M., Nivard, M. G., Nohr, E. A., Nolte, I. M., Ntalla, I., O'Reilly, P., Oberfield, S. E., Oken, E., Oldehinkel, A. J., Pahkala, K., Palviainen, T., Panoutsopoulou, K., Pedersen, Oluf Borbye, Pennell, C. E., Pershagen, G., Pitkanen, N., Plomin, R., Power, C., Prasad, R. B., Prokopenko, I., Pulkkinen, L., Raikkonen, K., Raitakari, O. T., Reynolds, R. M., Richmond, R. C., Rivadeneira, F., Rodriguez, A., Rose, R. J., Salem, R., Santa-Marina, L., Saw, S., Schnurr, T. M., Scott, J. G., Selzam, S., Shepherd, J. A., Simpson, A., Skotte, L., Sleiman, P. M. A., Snieder, H., Sørensen, Thorkild I.A., Standl, M., Steegers, E. A. P., Strachan, D. P., Straker, L., Strandberg, T., Taylor, M., Teo, Y., Thiering, E., Torrent, M., Tyrrell, J., Uitterlinden, A. G., van Beijsterveldt, T., van der Most, P. J., van Duijn, C. M., Viikari, J., Vilor-Tejedor, N., Vogelezang, S., Vonk, J. M., Vrijkotte, T. G. M., Vuoksimaa, E., Wang, C. A., Watkins, W. J., Wichmann, H., Willemsen, G., Williams, G. M., Wilson, J. F., Wray, N. R., Xu, S., Xu, C., Yaghootkar, H., Yi, L., Zafarmand, M. H., Zeggini, E., Zemel, B. S., Hinney, A., Lakka, T. A., Whitehouse, A. J. O., Sunyer, J., Widen, E. E., Feenstra, B., Sebert, S., Jacobsson, B., Njolstad, P. R., Stoltenberg, C., Smith, G. D., Lawlor, D. A., Paternoster, L., Timpson, N. J., Ong, K. K., Bisgaard, H., Bønnelykke, Klaus, Jaddoe, V. W. V., Tiemeier, H., Jarvelin, M., Evans, D. M., Perry, J. R. B., Grant, S. F. A., Boomsma, D. I., Freathy, R. M., McCarthy, M. I., Adair, L. S., Ahlqvist, E., Ahluwalia, Tarun Veer Singh, Almgren, P., Ang, W., Atalay, M., Beaumont, R. N., Beckmann, J. S., Bisgaard, H., Bond, T., Bønnelykke, Klaus, Boomsma, D. I., Borja, J. B., Bradfield, J. P., Bustamante, M., Cavadino, A., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Curtin, J. A., Custovic, A., Das, S., Day, F. R., De Silva, N. M., Dedoussis, G. V., Elliott, P., Eriksson, J. G., Evans, D. M., Fadista, J., Feenstra, B., Felix, J. F., Frayling, T. M., Freathy, R. M., Gaillard, R., Geller, F., Gilsanz, V., Grant, S. F. A., Grarup, Niels, Groop, L., Guxens, M., Hadley, D., Hakonarson, H., Hansen, Torben, Hattersley, A. T., Hayes, M. G., Hebebrand, J., Heinrich, J., Helgeland, O., Henriksen, T. B., Hinney, A., Hirschhorn, J. N., Hivert, M., Hocher, B., Holloway, J. W., Horikoshi, M., Hottenga, J., Hypponen, E., Jacobsson, B., Jaddoe, V. W. V., Jarvelin, M., Johansson, S., Kalkwarf, H. J., Kerkhof, M., Korner, A., Kotecha, S., Kreiner-Moller, E., Kulohoma, B., Kutalik, Z., Lakka, T. A., Lappe, J. M., Lawlor, D. A., Lehtimaki, T., Lewin, A. M., Lindgren, C. M., Lindi, V., Linneberg, Allan René, Liu, X., Liu, J., Lowe, W. L. ,. J., Ma, R. C. W., Mace, A., Magi, R., Magnus, P., Mahajan, A., McCarthy, N. S., McCarthy, M. I., Melbye, M., Mohlke, K. L., Monnereau, C., Mook-Kanamori, D. O., Morgen, C. S., Morris, A. P., Murray, J. C., Myhre, R., Njolstad, P. R., Nohr, E. A., Ntalla, I., O'Reilly, P., Oberfield, S. E., Oken, E., Ong, K. K., Panoutsopoulou, K., Pedersen, Oluf Borbye, Pennell, C. E., Perry, J. R. B., Pitkanen, N., St Pourcain, B., Power, C., Prasad, R. B., Prokopenko, I., Raitakari, O. T., Reynolds, R. M., Richmond, R. C., Rodriguez, A., Salem, R., Saw, S., Schnurr, T. M., Sebert, S., Shepherd, J. A., Simpson, A., Skotte, L., Sørensen, Thorkild I.A., Standl, M., Steegers, E. A. P., Strachan, D. P., Sunyer, J., Taylor, M., Teo, Y., Thiering, E., Timpson, N. J., Tyrrell, J., Uitterlinden, A. G., van Duijn, C. M., Vogelezang, S., Vrijkotte, T. G. M., Wang, C. A., Warrington, N. M., Watkins, W. J., Wichmann, H., Widen, E. E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zafarmand, M. H., Zeggini, E., Zemel, B. S., Ahluwalia, T. S., Auvinen, J., Bartels, M., Bilbao, J. R., Bisgaard, H., Bønnelykke, Klaus, Boomsma, D. I., Bradfield, J. P., Bustamante, M., Chen, Z., Curtin, J. A., Custovic, A., Smith, G. D., Davies, G. E., Duijts, L., Eastwood, P. R., Eliasen, A. U., Estivill, X., Evans, D. M., Fedko, I. O., Felix, J. F., Gauderman, W. J., Gilliland, F., Granell, R., Grant, S. F. A., Guxens, M., Hakonarson, H., Hartman, C. A., Heinrich, J., Henders, A. K., Henderson, J., Holt, P., Hottenga, J., Hypponen, E., Iniguez, C., Jacobsson, B., Jaddoe, V. W. V., Jarvelin, M., Jugessur, A., Kahonen, M., Kaprio, J., Karhunen, V., Kemp, J. P., Koppelman, G. H., Kumar, A., Lahti, J., Larsson, Henrik Bo Wiberg, Lawlor, D. A., Lehtimaki, T., Li, J., Lichtenstein, P., Lundstrom, S., Lyytikainen, L., Magnus, P., Mamun, A. A., Mannikko, M., Martin, N. G., Mbarek, H., Medland, S. E., Melen, E., Middeldorp, C. M., Najman, J. M., Nivard, M. G., Nolte, I. M., Oldehinkel, A. J., Pahkala, K., Palviainen, T., Paternoster, L., Pennell, C. E., Pershagen, G., Pitkanen, N., Plomin, R., St Pourcain, B., Power, C., Pulkkinen, L., Raikkonen, K., Raitakari, O. T., Richmond, R. C., Rivadeneira, F., Rose, R. J., Santa-Marina, L., Scott, J. G., Sebert, S., Selzam, S., Simpson, A., Sleiman, P. M. A., Snieder, H., Standl, M., Stoltenberg, C., Strachan, D. P., Straker, L., Strandberg, T., Sunyer, J., Thiering, E., Tiemeier, H., Timpson, N. J., Torrent, M., Uitterlinden, A. G., van Beijsterveldt, T., van der Most, P. J., van Duijn, C. M., Viikari, J., Vilor-Tejedor, N., Vonk, J. M., Vrijkotte, T. G. M., Vuoksimaa, E., Wang, C. A., Whitehouse, A. J. O., Willemsen, G., Williams, G. M., Wray, N. R., Xu, S., Xu, C., Yi, L. & Zafarmand, M. H., 2019, In: European Journal of Epidemiology. 34, 3, p. 279-300 22 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The role of the 17q21 genotype in the prevention of early childhood asthma and recurrent wheeze by vitamin D

Kelly, R. S., Chawes, Bo Lund Krogsgaard, Guo, F., Zhang, L., Blighe, K., Litonjua, A. A., Raby, B. A., Levy, B. D., Rago, D., Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, H., Zhou, X., Lasky-Su, J. A. & Weiss, S. T., 2019, In: The European Respiratory Journal. 54, 4, 11 p., 1900761.

Research output: Contribution to journal › Journal article › Research › peer-review

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

Kachroo, P., Hecker, J., Chawes, B. L., Ahluwalia, T. S., Cho, M. H., Qiao, D., Kelly, R. S., Chu, S. H., Virkud, Y. V., Huang, M., Barnes, K. C., Burchard, E. G., Eng, C., Hu, D., Celedón, J. C., Daya, M., Levin, A. M., Gui, H., Williams, L. K., Forno, E. & 31 others, Mak, A. C. Y., Avila, L., Soto-Quiros, M. E., Cloutier, M. M., Acosta-Pérez, E., Canino, G., Bønnelykke, Klaus, Bisgaard, H., Raby, B. A., Lange, C., Weiss, S. T., Lasky-Su, J. A., Abe, N., Abecasis, G., Albert, C., Palmer Allred, N. (., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Loos, Ruth & National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, N. H. L. A. B. I. T. F. P. M. (. C., 2019, In: Chest. 156, 6, p. 1068-1079 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Data representations and -analyses of binary diary data in pursuit of stratifying children based on common childhood illnesses

de Rooi, J., Nørgaard, S. K., Rasmussen, Morten Arendt, Bønnelykke, Klaus, Bisgaard, H. & Smilde, Age Klaas, 29 Nov 2018, In: PLOS ONE. 13, 11, p. 1-15 e0207177.

Research output: Contribution to journal › Journal article › Research › peer-review

17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use

Farzan, N., Vijverberg, S. J., Hernandez-Pacheco, N., Bel, E. H. D., Berce, V., Bønnelykke, K., Bisgaard, H., Burchard, E. G., Canino, G., Celedón, J. C., Chew, F. T., Chiang, W. C., Cloutier, M. M., Forno, E., Francis, B., Hawcutt, D. B., Herrera-Luis, E., Kabesch, M., Karimi, L., Melén, E. & 19 others, Mukhopadhyay, S., Merid, S. K., Palmer, C. N., Pino-Yanes, M., Pirmohamed, M., Potočnik, U., Repnik, K., Schieck, M., Sevelsted, A., Sio, Y. Y., Smyth, R. L., Soares, P., Söderhäll, C., Tantisira, K. G., Tavendale, R., Tse, S. M., Turner, S., Verhamme, K. M. & Maitland-van der Zee, A., 2018, In: Allergy. 73, 10, p. 2083-2088 6 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

NKG2D gene variation and susceptibility to viral bronchiolitis in childhood

Pasanen, A., Karjalainen, M. K., Kummola, L., Waage, J., Bønnelykke, Klaus, Ruotsalainen, M., Piippo-Savolainen, E., Goksör, E., Nuolivirta, K., Chawes, Bo Lund Krogsgaard, Vissing, N., Bisgaard, H., Jartti, T., Wennergren, G., Junttila, I., Hallman, M., Korppi, M. & Rämet, M., 2018, In: Pediatric Research. 84, p. 451-457

Research output: Contribution to journal › Journal article › Research › peer-review

A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle

Stein, M. M., Thompson, E. E., Schoettler, N., Helling, B. A., Magnaye, K. M., Stanhope, C., Igartua, C., Morin, A., Washington, C., Nicolae, D., Bønnelykke, Klaus & Ober, C., 2018, In: Journal of Allergy and Clinical Immunology. 142, 3, p. 749-764.e3

Research output: Contribution to journal › Review › Research › peer-review

Cadherin-related Family Member 3 Genetics and Rhinovirus C Respiratory Illnesses

Bønnelykke, Klaus, Coleman, A. T., Evans, M. D., Thorsen, Jonathan Jan Ilve, Waage, J., Vissing, N. H., Carlsson, C. J., Stokholm, Jakob, Chawes, Bo Lund Krogsgaard, Jessen, L. E., Fischer, T. K., Bochkov, Y. A., Ober, C., Lemanske, R. F., Jackson, D. J., Gern, J. E. & Bisgaard, H., 2018, In: American Journal of Respiratory and Critical Care Medicine. 197, 5, p. 589-594 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant

Stokholm, Jakob, Chawes, Bo Lund Krogsgaard, Vissing, N., Bønnelykke, Klaus & Bisgaard, H., 2018, In: Journal of Allergy and Clinical Immunology. 141, 5, p. 1598-1606 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Consortium-based genome-wide meta-analysis for childhood dental caries traits

Haworth, S., Shungin, D., Van Der Tas, J. T., Vucic, S., Medina-Gomez, C., Yakimov, V., Feenstra, B., Shaffer, J. R., Lee, M. K., Standl, M., Thiering, E., Wang, C., Bønnelykke, K., Waage, J., Jessen, L. E., Nørrisgaard, P. E., Joro, R., Seppälä, I., Raitakari, O., Dudding, T. & 23 others, Grgic, O., Ongkosuwito, E., Vierola, A., Eloranta, A. M., West, N. X., Thomas, S. J., McNeil, D. W., Levy, S. M., Slayton, R., Nohr, E. A., Lehtimäki, T., Lakka, T., Bisgaard, H., Pennell, C., Kühnisch, J., Marazita, M. L., Melbye, M., Geller, F., Rivadeneira, F., Wolvius, E. B., Franks, P. W., Johansson, I. & Timpson, N. J., 2018, In: Human Molecular Genetics. 27, 17, p. 3113-3127

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial

Vinding, R. K., Stokholm, Jakob, Sevelsted, A., Sejersen, T., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Thorsen, Jonathan Jan Ilve, Howe, L. D., Krakauer, M. & Bisgaard, H., 2018, In: BMJ (Clinical research ed.). 362, p. 1-9 9 p., k3312.

Research output: Contribution to journal › Journal article › Research › peer-review