Niels Erik Skakkebæk

Niels Erik Skakkebæk

Affiliate Professor

Member of:

  • Paediatrics


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  1. Published

    Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men: 2009–2017

    Frederiksen, H., Nielsen, O., Koch, H. M., Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Andersson, A. M., Jan 2020, In: International Journal of Hygiene and Environmental Health. 223, 1, p. 93-105

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Human urinary excretion of non-persistent environmental chemicals: an overview of Danish data collected between 2006 and 2012

    Frederiksen, H., Jensen, T. K., Jørgensen, N., Kyhl, H. B., Husby, S., Skakkebæk, Niels Erik, Main, Katharina Maria, Juul, Anders & Andersson, A., 2014, In: Reproduction. 147, 4, p. 555-565 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents

    Frederiksen, H., Nielsen, O., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A., Mar 2017, In: International Journal of Hygiene and Environmental Health. 220, 2, Part A, p. 244-253 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Immunohistochemical expression of embryonal marker TRA-1-60 in carcinoma in situ and germ cell tumors of the testis

    Giwercman, A., Andrews, P. W., Jørgensen, N., Müller, J., Graem, N. & Skakkebæk, Niels Erik, 15 Aug 1993, In: Cancer. 72, 4, p. 1308-14 7 p.

    Research output: Contribution to journal › Journal article › Research

  5. Published

    The faroes statement: human health effects of developmental exposure to chemicals in our environment

    Grandjean, P., Bellinger, D., Bergman, A., Cordier, S., vey-Smith, G., Eskenazi, B., Gee, D., Gray, K., Hanson, M., den, H. P. V., Heindel, J. J., Heinzow, B., Hertz-Picciotto, I., Hu, H., Huang, T. T., Jensen, T. K., Landrigan, P. J., McMillen, I. C., Murata, K., Ritz, B. & 4 others, Schoeters, G., Skerfving, S., Weihe, P. & Skakkebæk, Niels Erik, 2008, In: Basic & Clinical Pharmacology & Toxicology. 102, 2, p. 73-75 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Association Between Use of Marijuana and Male Reproductive Hormones and Semen Quality: A Study Among 1,215 Healthy Young Men

    Gundersen, T. D., Jørgensen, N., Andersson, A., Bang, A. K., Nordkap, L., Skakkebæk, Niels Erik, Priskorn, L., Juul, Anders & Jensen, T. K., 2015, In: American Journal of Epidemiology. 182, 6, p. 473-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Cardiovascular risk factors in men: The role of gonadal steroids and sex hormone-binding globulin

    Gyllenborg, J., Rasmussen, S. L., Borch-Johnsen, K., Heitmann, B. L., Skakkebæk, Niels Erik & Juul, Anders, 2001, In: Metabolism. 50, 8, p. 882-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Low concentration of circulating antimüllerian hormone is not predictive of reduced fecundability in young healthy women: a prospective cohort study

    Hagen, C. P., Vestergaard, S., Juul, Anders, Skakkebæk, Niels Erik, Andersson, A., Main, Katharina Maria, Hjøllund, N. H., Ernst, E., Bonde, Jens Peter, Anderson, R. A. & Jensen, T. K., 2012, In: Fertility and Sterility. 98, 6, p. 1602-8.e2

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Identification and expression profiling of 10 novel spermatid expressed CYPT genes

    Hansen, M. A., Nielsen, J. E., Tanaka, M., Almstrup, Kristian, Skakkebæk, Niels Erik & Leffers, H., May 2006, In: Molecular Reproduction and Development. 73, 5, p. 568-579 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Proceedings: 17beta-hydroxysteroid oxidoreductase deficiency causing male pseudohermaphroditism in a child

    Harkness, R. A., Thistlethwaite, D., Darling, J. A., Skakkebæk, Niels Erik & Corker, C. S., 1 Nov 1975, In: Journal of Endocrinology. 67, 2, p. 16P-17P

    Research output: Contribution to journal › Journal article › Research

  11. Published

    Early Life Events Predict Adult Testicular Function: Data Derived From the Western Australian (Raine) Birth Cohort

    Hart, R. J., Doherty, D. A., Keelan, J. A., McLachlan, R., Skakkebæk, Niels Erik, Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In: The Journal of clinical endocrinology and metabolism. 101, 9, p. 3333-3344 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The possible impact of antenatal exposure to ubiquitous phthalates upon male reproductive function at 20 years of age

    Hart, R. J., Frederiksen, H., Doherty, D. A., Keelan, J. A., Skakkebæk, Niels Erik, Minaee, N. S., McLachlan, R., Newnham, J. P., Dickinson, J. E., Pennell, C. E., Norman, R. J. & Main, Katharina Maria, 2018, In: Frontiers in Endocrinology. 9, JUN, 11 p., 288.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Male reproductive disorders, diseases, and costs of exposure to endocrine-disrupting chemicals in the European Union

    Hauser, R., Skakkebæk, Niels Erik, Hass, U., Toppari, J., Juul, Anders, Andersson, A. M., Kortenkamp, A., Heindel, J. J. & Trasande, L., Apr 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 4, p. 1267-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

    Henriksen, L. S., Mathiesen, B. K., Assens, M., Krause, M., Skakkebæk, Niels Erik, Juul, Anders, Andersson, A. M., Hart, R. J., Newnham, J. P., Keelan, J. A., Pennell, C., Main, Katharina Maria & Frederiksen, H., 2020, In: Environmental Research. 184, 109231.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Reproductive hormone levels in Minipuberty as a predictor of Testicular Endocrine Function and Penile Length in Healthy Young Men: An 18-year longitudinal Cohort Study

    Henriksen, L. S., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Jørgensen, N., Virtanen, H. E., Juul, Anders, Toppari, J. & Main, Katharina Maria, 2021, In: Hormone Research in Paediatrics. 94, SUPPL 1, p. 41-42 2 p., FC5.4.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  16. Published

    Maternal phthalate exposure during pregnancy and testis function of young adult sons

    Henriksen, L. S., Frederiksen, H., Jørgensen, N., Juul, Anders, Skakkebæk, Niels Erik, Toppari, J., Petersen, Jørgen Holm & Main, Katharina Maria, 2023, In: Science of the Total Environment. 871, 12 p., 161914.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Genetic variations in FSH action affect sex hormone levels and breast tissue size in infant girls: A pilot study

    Henriksen, L. S., Hagen, C. P., Assens, M., Busch, A. S., Skakkebæk, Niels Erik, Almstrup, K. & Main, Katharina Maria, 1 Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3191-3198 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Serum concentrations of type I and III procollagen propeptides in healthy children and girls with central precocious puberty during treatment with gonadotropin-releasing hormone analog and cyproterone acetate

    Hertel, N., Stoltenberg, M., Juul, Anders, Main, Katharina Maria, Müller, J., Nielsen, C. T., Lorenzen, I. & Skakkebæk, Niels Erik, 1993, In: Journal of Clinical Endocrinology and Metabolism. 76, 4, p. 924-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Pilocarpine iontophoresis test: an index of physiological sweat secretion?

    Hjortskov, N., Jepsen, L., Nielsen, B., Juul, Anders & Skakkebæk, Niels Erik, 1995, In: Clinical physiology (Oxford, England). 15, 4, p. 409-14 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours

    Hoei-Hansen, C. E., Almstrup, Kristian, Nielsen, J. E., Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2005, In: Histopathology. 47, 1, p. 48-56 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2γ in semen samples: Case report

    Høi-Hansen, Christina Engel, Rajpert-De Meyts, E., Carlsen, E., Almstrup, Kristian, Leffers, H. & Skakkebæk, Niels Erik, Mar 2005, In: Human Reproduction. 20, 3, p. 579-582 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Identification of genes differentially expressed in testes containing carcinoma in situ

    Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-DeMeyts, E. & Leffers, H., Jun 2004, In: Molecular Human Reproduction. 10, 6, p. 423-431 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Transcription factor AP-2γ is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors

    Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2004, In: Clinical Cancer Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors

    Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, K., Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2004, In: Clinical Cancer Research. 10, 24, p. 8521-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer

    Hoei-Hansen, C. E., Holm, M., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Jul 2003, In: Journal of Pathology. 200, 3, p. 370-4 5 p.

    Research output: Contribution to journal › Journal article › Research

  26. Published

    Re: Niels J. van Casteren, Hans Stoop, Gert R. Dohle, Ronald de Wit, J. Wolter Oosterhuis, Leendert H.J. Looijenga. Noninvasive Detection of Testicular Carcinoma In Situ in Semen Using OCT3/4. Eur Urol 2008;54:153-60

    Høi-Hansen, Christina Engel, Almstrup, Kristian, Skakkebæk, Niels Erik & Rajpert-De Meyts, E., Apr 2009, In: European Urology. 55, 4, p. e67-e68

    Research output: Contribution to journal › Letter › Research › peer-review

  27. Published

    Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle

    Holm, M., Hoei-Hansen, C. E., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Oct 2003, In: Journal of Urology. 170, 4 Pt 1, p. 1163-7 5 p.

    Research output: Contribution to journal › Journal article › Research

  28. Published

    Leydig cell micronodules are a common finding in testicular biopsies from men with impaired spermatogenesis and are associated with decreased testosterone/LH ratio

    Holm, M., Rajpert-De Meyts, E., Andersson, A. & Skakkebæk, Niels Erik, 1 Mar 2003, In: Journal of Pathology. 199, 3, p. 378-86 9 p.

    Research output: Contribution to journal › Journal article › Research

  29. Published

    Influence of marital status on testosterone levels-A ten year follow-up of 1113 men

    Holmboe, S. A., Priskorn, L., Jørgensen, N., Skakkebæk, Niels Erik, Linneberg, Allan René, Juul, Anders & Andersson, A., 2017, In: Psychoneuroendocrinology. 80, p. 155-161 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Free testosterone and cardiometabolic parameters in men: Comparison of algorithms

    Holmboe, S. A., Jasuja, R., Lawney, B., Priskorn, L., Joergensen, N., Linneberg, Allan René, Jensen, T. K., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A. M., 2021, In: Endocrine Connections. 10, 2, p. 220-229 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The epidemiology of cryptorchidism and potential risk factors, including endocrine disrupting chemicals

    Holmboe, S. A., Beck, A. L., Andersson, A. M., Main, Katharina Maria, Jørgensen, N., Skakkebæk, Niels Erik & Priskorn, L., 2024, In: Frontiers in Endocrinology. 15, 8 p., 1343887.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Prenatal exposure to phenols and benzophenones in relation to markers of male reproductive function in adulthood

    Holmboe, S. A., Scheutz Henriksen, L., Frederiksen, H., Andersson, A. M., Priskorn, Lærke, Jørgensen, N., Juul, Anders, Toppari, J., Skakkebæk, Niels Erik & Main, Katharina Maria, 2022, In: Frontiers in Endocrinology. 13, 1071761.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Low Testosterone: A Risk Marker Rather Than a Risk Factor for Type 2 Diabetes

    Holmboe, S. A., Jensen, T. K., Linneberg, Allan René, Scheike, Thomas, Thuesen, B. H., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A. M., Aug 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 8, p. 3180-3190 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Individual testosterone decline and future mortality risk in men

    Holmboe, S. A., Skakkebæk, Niels Erik, Juul, Anders, Scheike, Thomas, Jensen, T. K., Linneberg, Allan René, Thuesen, B. H. & Andersson, A., Jan 2018, In: European Journal of Endocrinology. 178, p. 121-128

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Use of e-cigarettes associated with lower sperm counts in a cross-sectional study of young men from the general population

    Holmboe, S. A., Priskorn, L., Jensen, T. K., Skakkebæk, Niels Erik, Andersson, A. & Jørgensen, N., Jul 2020, In: Human Reproduction. 35, 7, p. 1693-1701

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    A controlled study on serum insulin-like growth factor-I and urinary excretion of growth hormone in fibromyalgia

    Jacobsen, S., Main, Katharina Maria, Danneskiold-Samsøe, B. & Skakkebæk, Niels Erik, 1 Jun 1995, In: Journal of Rheumatology. 22, 6, p. 1138-40 3 p.

    Research output: Contribution to journal › Journal article › Research

  37. Published

    Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans

    Janjua, N. R., Frederiksen, H., Skakkebæk, Niels Erik, Wulf, H. C. & Andersson, A., 1 Apr 2008, In: International Journal of Andrology. 31, 2, p. 118-30 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Expression of the vitamin D metabolizing enzyme CYP24A1 at the annulus of human spermatozoa may serve as a novel marker of semen quality

    Jensen, Martin Blomberg, Jørgensen, A., Nielsen, Jens Erik Klint, Bjerrum, P. J., Skalkam, M., Petersen, Jørgen Holm, Egeberg, D. L., Bangsbøll, S., Andersen, A. N., Skakkebæk, Niels Erik, Juul, Anders, Rajpert-De Meyts, E., Dissing, Steen, Leffers, H. & Jørgensen, N., 2012, In: International Journal of Andrology. 35, 4, p. 499-510 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Temporal Trends in Fertility Rates: A Nationwide Registry Based Study from 1901 to 2014

    Jensen, M. B., Priskorn, L., Jensen, T. K., Juul, Anders & Skakkebæk, Niels Erik, 2015, In: P L o S One. 10, 12, p. 1-10 10 p., e0143722.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Insulin-like growth factor I (IGF-I) and IGF-binding protein 3 as diagnostic markers of growth hormone deficiency in infancy

    Jensen, R. B., Jeppesen, K. A., Vielwerth, S., Michaelsen, K. F., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Hormone Research. 63, 1, p. 15-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: does insulin-like growth factor-I play a role?

    Jensen, R. B. B., Chellakooty, M., Vielwerth, S., Vaag, Allan, Larsen, T. K., Greisen, Gorm, Skakkebæk, Niels Erik, Scheike, T. H. & Juul, Anders, 2003, In: Hormone Research. 60 Suppl 3, p. 136-48 13 p.

    Research output: Contribution to journal › Journal article › Research

  42. Published

    Self-rated health and semen quality among 3,457 young Danish men

    Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Kristensen, T. S., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Nov 2007, In: Fertility and Sterility. 88, 5, p. 1366-73 8 p.

    Research output: Contribution to journal › Journal article › Research

  43. Published

    Habitual alcohol consumption associated with reduced semen quality and changes in reproductive hormones; a cross-sectional study among 1221 young Danish men

    Jensen, T. K., Gottschau, M., Madsen, J. O. B., Andersson, A., Lassen, T. H., Skakkebæk, Niels Erik, Swan, S. H., Priskorn, L., Juul, Anders & Jørgensen, N., 2014, In: B M J Open. 4, 9, p. 1-11 11 p., e005462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Poor semen quality may contribute to recent decline in fertility rates

    Jensen, T. K., Carlsen, E., Jørgensen, N., Berthelsen, J. G., Keiding, N., Christensen, K., Petersen, Jørgen Holm, Knudsen, L. B. & Skakkebæk, Niels Erik, 2002, In: Human Reproduction. 17, 6, p. 1437-40 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general population

    Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Mar 2007, In: American Journal of Epidemiology. 165, 5, p. 583-90 8 p.

    Research output: Contribution to journal › Journal article › Research

  46. Published

    Caffeine intake and semen quality in a population of 2,554 young Danish men

    Jensen, T. K., Swan, S. H., Skakkebæk, Niels Erik, Rasmussen, S. & Jørgensen, N., 15 Apr 2010, In: American Journal of Epidemiology. 171, 8, p. 883-91 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Prenatal Exposure to Phthalates and Anogenital Distance in Male Infants from a Low-Exposed Danish Cohort (2010-2012)

    Jensen, T. K., Frederiksen, H., Kyhl, H. B., Lassen, T. H., Swan, S. H., Bornehag, C., Skakkebæk, Niels Erik, Main, Katharina Maria, Lind, D. V., Husby, S. & Andersson, A., Jul 2016, In: Environmental Health Perspectives. 124, 7, p. 1107-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Self-reported onset of puberty and subsequent semen quality and reproductive hormones in healthy young men

    Jensen, T. K., Finne, K. F., Skakkebæk, Niels Erik, Andersson, A., Olesen, I. A., Joensen, U. N., Bang, A. K., Nordkap, L., Priskorn, L., Krause, M., Jørgensen, N. & Juul, Anders, 2016, In: Human Reproduction. 31, 8, p. 1886-1894 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Do environmental estrogens contribute to the decline in male reproductive health?

    Jensen, T. K., Toppari, J., Keiding, N. & Skakkebæk, Niels Erik, Dec 1995, In: Clinical Chemistry. 41, 12, p. 1896-1901 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview

    Jensen, T. K., Skakkebæk, Niels Erik, Jørgensen, N., Jensen, M. B. & Juul, Anders, 2011, In: Ugeskrift for Laeger. 173, 50, p. 3253-5 3 p.

    Research output: Contribution to journal › Comment/debate › Research

  51. Published

    Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries

    Jensen, T. K., Jørgensen, N., Punab, M., Haugen, T. B., Suominen, J., Zilaitiene, B., Horte, A., Andersen, A., Carlsen, E., Magnus, Ø., Matulevicius, V., Nermoen, I., Vierula, M., Keiding, N., Toppari, J. & Skakkebæk, Niels Erik, 2004, In: American Journal of Epidemiology. 159, 1, p. 49-58 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Distinguishing between hidden testes and anorchia: The role of endocrine evaluation in infancy and childhood

    Jespersen, K., Ljubicic, M. L., Johannsen, T. H., Christiansen, P., Skakkebæk, Niels Erik & Juul, Anders, 2020, In: European Journal of Endocrinology. 183, 1, p. 107-117 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Exposure to phenols, parabens and UV filters: Associations with loss-of-function mutations in the filaggrin gene in men from the general population

    Joensen, U. N., Jørgensen, N., Thyssen, Jacob Pontoppidan, Petersen, Jørgen Holm, Szecsi, P. B., Stender, S., Andersson, A. M., Skakkebæk, Niels Erik & Frederiksen, H., 2017, In: Environment International. 105, p. 105-111

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Testicular dysgenesis syndrome and carcinoma in situ of the testes

    Joensen, Ulla Nordström, Jorgensen, N. & Skakkebæk, Niels Erik, Aug 2007, In: Nature Clinical Practice Urology. 4, 8, p. 402-403 2 p.

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Erratum: PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men (Human Reproduction (2013) 28 (599-608))

    Joensen, Ulla Nordström, Veyrand, B., Antignac, J. P., Jensen, Martin Blomberg, Petersen, Jørgen Holm, Marchand, P., Skakkebæk, Niels Erik, Andersson, A. M., Le Bizec, B. & Jorgensen, N., 2014, In: Human Reproduction. 29, 7, p. 1600 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  56. Published

    Is there a problem with male reproduction?

    Joensen, Ulla Nordström, Skakkebæk, Niels Erik & Jørgensen, N., 2009, In: Nature Clinical Practice Endocrinology & Metabolism. 5, 3, p. 144-5 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men

    Joensen, Ulla Nordström, Veyrand, B., Antignac, J. P., Jensen, Martin Blomberg, Petersen, Jørgen Holm, Marchand, P., Skakkebæk, Niels Erik, Andersson, A. M., Le Bizec, B. & Jørgensen, N., Mar 2013, In: Human Reproduction. 28, 3, p. 599-608 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Do perfluoroalkyl compounds impair human semen quality?

    Joensen, Ulla Nordström, Bossi, R., Leffers, H., Jensen, A. A., Skakkebæk, Niels Erik & Jørgensen, N., 2009, In: Environmental Health Perspectives. 117, 6, p. 923-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Associations of Filaggrin Gene Loss-of-Function Variants with Urinary Phthalate Metabolites and Testicular Function in Young Danish Men

    Joensen, U. N., Jørgensen, N., Meldgaard, M., Frederiksen, H., Andersson, A., Menné, T., Johansen, Jeanne Duus, Carlsen, B. C., Stender, S., Szecsi, P. B., Skakkebæk, Niels Erik, De Meyts, E. R. & Thyssen, Jacob Pontoppidan, Apr 2014, In: Environmental Health Perspectives. 122, 4, p. 345-350 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Serum concentrations of free and total insulin-like growth factor-I, IGF binding proteins -1 and -3 and IGFBP-3 protease activity in boys with normal or precocious puberty

    Juul, Anders, Flyvbjerg, A., Frystyk, J., Müller, J. & Skakkebæk, Niels Erik, 1996, In: Clinical Endocrinology. 44, 5, p. 515-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Impaired thermoregulation in adults with growth hormone deficiency during heat exposure and exercise

    Juul, Anders, Behrenscheer, A., Tims, T., Nielsen, B., Halkjaer-Kristensen, J. & Skakkebæk, Niels Erik, 1993, In: Clinical Endocrinology. 38, 3, p. 237-244 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Prediction of the outcome of growth hormone provocative testing in short children by measurement of serum levels of insulin-like growth factor I and insulin-like growth factor binding protein 3

    Juul, Anders & Skakkebæk, Niels Erik, 1997, In: Journal of Pediatrics. 130, 2, p. 197-204 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Growth hormone deficiency and hyperthermia during exercise: a controlled study of sixteen GH-deficient patients

    Juul, Anders, Hjortskov, N., Jepsen, L., Nielsen, B., Halkjaer-Kristensen, J., Vahl, N., Jørgensen, J. O., Christiansen, J. S. & Skakkebæk, Niels Erik, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 11, p. 3335-40 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation

    Juul, Anders, Dalgaard, P., Blum, W. F., Bang, P., Hall, K. P., Michaelsen, K. F., Müller, J. & Skakkebæk, Niels Erik, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 8, p. 2534-42 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index

    Juul, Anders, Bang, P., Hertel, N., Main, Katharina Maria, Dalgaard, P., Jørgensen, K., Müller, J., Hall, K. P. & Skakkebæk, Niels Erik, 1994, In: Journal of Clinical Endocrinology and Metabolism. 78, 3, p. 744-52 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Growth hormone (GH) provocative retesting of 108 young adults with childhood-onset GH deficiency and the diagnostic value of insulin-like growth factor I (IGF-I) and IGF-binding protein-3

    Juul, Anders, Kastrup, K. W., Pedersen, S. A. & Skakkebæk, Niels Erik, 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 4, p. 1195-201 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Growth hormone deficiency and hyperthermia

    Juul, Anders & Skakkebæk, Niels Erik, 1991, In: Lancet. 338, 8771, p. 887

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Effects of growth hormone replacement therapy on IGF-related parameters and on the pituitary-gonadal axis in GH-deficient males. A double-blind, placebo-controlled crossover study

    Juul, Anders, Andersson, A. M., Pedersen, S. A., Jørgensen, J. O., Christiansen, J. S., Groome, N. P. & Skakkebæk, Niels Erik, 1998, In: Hormone Research. 49, 6, p. 269-78 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Pubertal development in Danish children: comparison of recent European and US data

    Juul, Anders, Teilmann, Grete Katrine, Scheike, T. H., Hertel, N., Holm, Kirsten, Laursen, E., Main, Katharina Maria & Skakkebæk, Niels Erik, 2006, In: International Journal of Andrology. 29, 1, p. 247-55; discussion 286-90

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Preserved fertility in a non-mosaic Klinefelter patient with a mutation in the fibroblast growth factor receptor 3 gene: case report

    Juul, Anders, Aksglaede, L., Lund, Allan Meldgaard, Duno, M., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 2007, In: Human Reproduction. 22, 7, p. 1907-11 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    The ratio between serum levels of insulin-like growth factor (IGF)-I and the IGF binding proteins (IGFBP-1, 2 and 3) decreases with age in healthy adults and is increased in acromegalic patients

    Juul, Anders, Main, Katharina Maria, Blum, W. F., Lindholm, J., Ranke, M. B. & Skakkebæk, Niels Erik, 1994, In: Clinical Endocrinology. 41, 1, p. 85-93 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment

    Juul, Anders, Müller, J. & Skakkebæk, Niels Erik, 1997, In: European Journal of Endocrinology. 136, 4, p. 401-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Serum levels of growth hormone binding protein in children with normal and precocious puberty: relation to age, gender, body composition and gonadal steroids

    Juul, Anders, Fisker, S., Scheike, T. H., Hertel, T. K., Müller, J., Orskov, H. & Skakkebæk, Niels Erik, 2000, In: Clinical Endocrinology. 52, 2, p. 165-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    The acid-labile subunit of human ternary insulin-like growth factor binding protein complex in serum: hepatosplanchnic release, diurnal variation, circulating concentrations in healthy subjects, and diagnostic use in patients with growth hormone deficiency

    Juul, Anders, Møller, S., Mosfeldt-Laursen, E., Rasmussen, M. H., Scheike, T. H., Pedersen, S. A., Kastrup, K. W., Yu, H., Mistry, J., Rasmussen, S., Müller, J., Henriksen, J. & Skakkebæk, Niels Erik, 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 12, p. 4408-15 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Growth hormone (GH) treatment increases serum insulin-like growth factor binding protein-3, bone isoenzyme alkaline phosphatase and forearm bone mineral content in young adults with GH deficiency of childhood onset

    Juul, Anders, Pedersen, S. A., Sørensen, S., Winkler, K., Jørgensen, J. O., Christiansen, J. S. & Skakkebæk, Niels Erik, 1994, In: European Journal of Endocrinology. 131, 1, p. 41-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 levels are increased in central precocious puberty: effects of two different treatment regimens with gonadotropin-releasing hormone agonists, without or in combination with an antiandrogen (cyproterone acetate)

    Juul, Anders, Scheike, T. H., Nielsen, C. T., Krabbe, S., Müller, J. & Skakkebæk, Niels Erik, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 10, p. 3059-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Changes in serum concentrations of growth hormone, insulin, insulin-like growth factor and insulin-like growth factor-binding proteins 1 and 3 and urinary growth hormone excretion during the menstrual cycle

    Juul, Anders, Scheike, T. H., Pedersen, Anette Tønnes, Main, Katharina Maria, Andersson, A. M., Pedersen, L. M. & Skakkebæk, Niels Erik, 1997, In: Human Reproduction. 12, 10, p. 2123-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Free insulin-like growth factor I serum levels in 1430 healthy children and adults, and its diagnostic value in patients suspected of growth hormone deficiency

    Juul, Anders, Holm, Kirsten, Kastrup, K. W., Pedersen, S. A., Michaelsen, K. F., Scheike, T. H., Rasmussen, S., Müller, J. & Skakkebæk, Niels Erik, 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 8, p. 2497-502 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Testosteronbehandling af ældre mænd: den såkaldte andropause eksisterer ikke.

    Juul, Anders & Skakkebæk, Niels Erik, 2002, In: Ugeskrift for Laeger. 164, 42, p. 4941-2 2 p.

    Research output: Contribution to journal › Review › Research

  80. Published

    Possible fetal determinants of male infertility

    Juul, Anders, Almstrup, Kristian, Andersson, A., Jensen, T. K., Jørgensen, N., Main, K. M., Rajpert-De Meyts, E., Toppari, J. & Skakkebæk, Niels Erik, Sep 2014, In: Nature Reviews Endocrinology. 10, 9, p. 553-562 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  81. Published

    Androgens and the ageing male

    Juul, Anders & Skakkebæk, Niels Erik, 2002, In: Human Reproduction Update. 8, 5, p. 423-33 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Diagnosis of GH deficiency and use of GH in children with growth disorders. A report from the Drugs and Therapeutics Committee of European Society for paediatric Endocrinology

    Juul, Anders, Bernasconi, S., Chatelain, P., Hindsmarsh, P., Hochberg, Z., Hokke-Koelega, A., De Muinck Keizer-Schrama, S., Kiess, W., Oberfield, S., Strasburger, C., Volta, C., Westphal, O. & Skakkebæk, Niels Erik, 1999, In: Hormone Research. 51, p. 284-299 15 p.

    Research output: Contribution to journal › Review › Research

  83. Published

    Development: disorders of sex development-the tip of the iceberg?

    Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 1 Jan 2011, In: Nature Reviews Endocrinology. 7, 9, p. 504-5 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Age at voice break in Danish boys: effects of pre-pubertal body mass index and secular trend

    Juul, Anders, Magnusdottir, S., Scheike, T., Prytz, S. & Skakkebæk, Niels Erik, 1 Dec 2007, In: International Journal of Andrology. 30, 6, p. 537-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Klinefelter syndrome: the forgotten syndrome: basic and clinical questions posed to an international group of scientists

    Juul, Anders, Aksglaede, L., Bay, K., Grigor, K. M. & Skakkebæk, Niels Erik, 1 Jun 2011, In: Acta Paediatrica. 100, 6, p. 791-2 2 p.

    Research output: Contribution to journal › Conference article › Research

  86. Published

    Væksthormon - virker på andet end væksten.

    Juul, Anders & Skakkebæk, Niels Erik, 1997, Medicinsk Årbog 1997. p. 9-15 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  87. Published

    Metabolic effects of GH: a rationale for continued GH treatment of GH-deficient adults after cessation of linear growth.

    Juul, Anders, Jørgensen, J., Christiansen, J., Müller, J. & Skakkebæk, Niels Erik, 1995, In: Hormone Research. p. 64-72 8 p.

    Research output: Contribution to journal › Review › Research

  88. Published

    Growth hormone treatment in GH-deficient adults; therapeutic and diagnostic aspects.

    Juul, Anders, Jørgensen, J., müller, J. & Skakkebæk, Niels Erik, 1994, In: Clinical Pediatric Endocrinology. p. 63-71 8 p.

    Research output: Contribution to journal › Review › Research

  89. Published

    Why Do Normal Children Have Acromegalic Levels of IGF-I During Puberty?

    Juul, Anders & Skakkebæk, Niels Erik, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2770-2776

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    The Human Eccrine Sweat Gland: A possible GRowth hormone target organ ?

    Juul, Anders, Nielsen, B., Hjortskov, N., Main, Katharina Maria & Skakkebæk, Niels Erik, 1997, The Clinical Pharmacology of Sports and Exercise.. p. 223 7 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  91. Published

    GH-deficiency, sweating and thermoregulations

    Juul, Anders, Main, Katharina Maria, Hjortskov, N., Jepsen, L., Nielsen, B., Halkjær-Kristensen, J. & Skakkebæk, Niels Erik, 1996, Growth Hormone in adults; Physiological and clinical aspects. p. 246 5 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  92. Published

    Consequences of stopping Growth hormone (GH) therapy in young GH-deficient patients with childhood-onset disease

    Juul, Anders, Vahl, N., Jørgensen, J., Christiansen, J. & Skakkebæk, Niels Erik, 1998, In: Growth Hormone & I G F Research. p. 15-19 4 p.

    Research output: Contribution to journal › Review › Research

  93. Published

    Disorders of sexual differentiation-the tip of the iceberg?

    Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 2011, In: Nature Reviews Endocrinology. 7, p. 504-5 1 p.

    Research output: Contribution to journal › Letter › Research

  94. Published

    Vækst og Regeration

    Juul, Anders, Korndrup, J. & Skakkebæk, Niels Erik, 1999, Medicinsk Kompendium. 15 ed. p. 140-148 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  95. Published

    Growth hormone (GH), exercise performance, muscle strength and sweat production in healthy subjects and adults with GH deficiency

    Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 2000, Growth Hormone in adults; Physiological and clinical aspects. 2 ed. p. 281-300 19 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  96. Published

    Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis

    Jørgensen, A., Macdonald, J., Nielsen, J. E., Kilcoyne, K. R., Perlman, S., Lundvall, L., Langhoff Thuesen, L., Hare, Kristine Juul, Frederiksen, H., Andersson, A., Skakkebæk, Niels Erik, Juul, Anders, Sharpe, R. M., Rajpert-De Meyts, E. & Mitchell, R. T., 13 Nov 2018, In: Cell Reports. 25, 7, p. 1924-1937.e4

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Pathogenesis of germ cell neoplasia in testicular dysgenesis and disorders of sex development

    Jørgensen, A., Lindhardt Johansen, M., Juul, Anders, Skakkebæk, Niels Erik, Main, Katharina Maria & Rajpert-De Meyts, E., Sep 2015, In: Seminars in Cell and Developmental Biology. 45, p. 124-37 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Adult Growth Hormone Deficiency

    Jørgensen, J., Müller, J., Wolthers, T., Vahn, N., Juul, Anders & Skakkebæk, Niels Erik, 1994, In: Hormone Research. 42, p. 235-241 6 p.

    Research output: Contribution to journal › Review › Research

  99. Published

    Growth hormone (GH)-deficiency in adults: clinical features and effects of GH substitution.

    Jørgensen, J., Møller, J., Wolthers, T., Vahn, N., Juul, Anders, Skakkebæk, Niels Erik & Christiansen, J., 1994, In: The journal of pediatric endocrinology. p. 283-293 10 p.

    Research output: Contribution to journal › Journal article › Research

  100. Published

    Impact of growth hormone administration on other hormonal axes.

    Jørgensen, J., Ovesen, P., Juul, Anders, Hansen, T., Skakkebæk, Niels Erik & Christiansen, J., 1999, In: Hormone Research. 51, p. 121-126 5 p.

    Research output: Contribution to journal › Review › Research

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