Niels Erik Skakkebæk

Niels Erik Skakkebæk

Affiliate Professor

Member of:

  • Paediatrics


  1. 2003
  2. Published

    Leydig cell micronodules are a common finding in testicular biopsies from men with impaired spermatogenesis and are associated with decreased testosterone/LH ratio

    Holm, M., Rajpert-De Meyts, E., Andersson, A. & Skakkebæk, Niels Erik, 1 Mar 2003, In: Journal of Pathology. 199, 3, p. 378-86 9 p.

    Research output: Contribution to journalJournal articleResearch

  3. Published

    Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer

    Hoei-Hansen, C. E., Holm, M., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Jul 2003, In: Journal of Pathology. 200, 3, p. 370-4 5 p.

    Research output: Contribution to journalJournal articleResearch

  4. Published

    Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle

    Holm, M., Hoei-Hansen, C. E., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Oct 2003, In: Journal of Urology. 170, 4 Pt 1, p. 1163-7 5 p.

    Research output: Contribution to journalJournal articleResearch

  5. 2004
  6. Published

    Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries

    Jensen, T. K., Jørgensen, N., Punab, M., Haugen, T. B., Suominen, J., Zilaitiene, B., Horte, A., Andersen, A., Carlsen, E., Magnus, Ø., Matulevicius, V., Nermoen, I., Vierula, M., Keiding, N., Toppari, J. & Skakkebæk, Niels Erik, 2004, In: American Journal of Epidemiology. 159, 1, p. 49-58 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Do environmental factors play a role in the aetiology of carcinoma in situ testis and the testicular dysgenesis syndrome?

    Sonne, Si Brask, Hoei-Hansen, C. E., Fisher, J. S., Leffers, H., Rajpert-de Meyts, E. & Skakkebæk, Niels Erik, 2004, In: Verhandlungen der Deutschen Gesellschaft fur Pathologie. 88, p. 144-51 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors

    Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, K., Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2004, In: Clinical Cancer Research. 10, 24, p. 8521-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Transcription factor AP-2γ is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors

    Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2004, In: Clinical Cancer Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth

    Chellakooty, M., Vangsgaard, K., Larsen, T., Scheike, T., Falck-Larsen, J., Legarth, J., Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 1, p. 384-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Analysis of cell-type-specific gene expression during mouse spermatogenesis

    Almstrup, Kristian, Nielsen, J. E., Hansen, M. A., Tanaka, M., Skakkebæk, Niels Erik & Leffers, H., Jun 2004, In: Biology of Reproduction. 70, 6, p. 1751-1761 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Identification of genes differentially expressed in testes containing carcinoma in situ

    Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-DeMeyts, E. & Leffers, H., Jun 2004, In: Molecular Human Reproduction. 10, 6, p. 423-431 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling

    Almstrup, Kristian, Høi-Hansen, Christina Engel, Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jul 2004, In: Cancer Research. 64, 14, p. 4736-4743 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2005
  15. Published

    Behandling og udredning af mandlig infertilitet og hypogonadisme

    Carlsen, E., Jørgensen, N., Juul, Anders & Skakkebæk, Niels Erik, 2005, In: Maanedsskrift for Praktisk Laegegerning. 83, p. 1239-49 10 p.

    Research output: Contribution to journalReviewResearch

  16. Published

    Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ

    Almstrup, Kristian, Ottesen, A. M., Sonne, Si Brask, Hoei-Hansen, C. E., Leffers, H., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 2005, In: Cell and Tissue Research. 322, 1, p. 159-65 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Insulin-like growth factor I (IGF-I) and IGF-binding protein 3 as diagnostic markers of growth hormone deficiency in infancy

    Jensen, R. B., Jeppesen, K. A., Vielwerth, S., Michaelsen, K. F., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Hormone Research. 63, 1, p. 15-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries

    Teilmann, Grete Katrine, Pedersen, C., Jensen, T. K., Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Pediatrics. 116, 6, p. 1323-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours

    Hoei-Hansen, C. E., Almstrup, Kristian, Nielsen, J. E., Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2005, In: Histopathology. 47, 1, p. 48-56 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2γ in semen samples: Case report

    Høi-Hansen, Christina Engel, Rajpert-De Meyts, E., Carlsen, E., Almstrup, Kristian, Leffers, H. & Skakkebæk, Niels Erik, Mar 2005, In: Human Reproduction. 20, 3, p. 579-582 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours

    Almstrup, Kristian, Høi-Hansen, Christina Engel, Nielsen, J. E., Wirkner, U., Ansorge, W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 23 May 2005, In: British Journal of Cancer. 92, 10, p. 1934-1941 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2006
  23. Published

    A prospective study of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in 942 healthy infants: associations with birth weight, gender, growth velocity, and breastfeeding

    Chellakooty, M., Juul, A., Boisen, K. A., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Main, K. M., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 820-826 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours

    Sonne, Si Brask, Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, Kristian, Daugaard, G., Skakkebæk, Niels Erik, Leffers, H., Rajpert-De Meyts, E., Sonne, S. B., Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, K., Daugaard, G., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 114, 7-8, p. 549-58 10 p.

    Research output: Contribution to journalJournal articleResearch

  25. Published

    From embryonic stem cells to testicular germ cell cancer-- should we be concerned?

    Almstrup, Kristian, Sonne, Si Brask, Hoei-Hansen, C. E., Ottesen, A. M., Nielsen, J. E., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: International Journal of Andrology. 29, 1, p. 211-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age

    Main, Katharina Maria, Mortensen, G. K., Kaleva, M. M., Boisen, K. A., Damgaard, I. N., Chellakooty, M., Schmidt, I. M., Suomi, A., Virtanen, H. E., Petersen, J. H., Andersson, A., Toppari, J. & Skakkebæk, Niels Erik, 2006, In: Environmental Health Perspectives. 114, 2, p. 270-276 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours

    Sonne, Si Brask, Herlihy, A. S., Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, Kristian, Skakkebæk, Niels Erik, Marks, A., Leffers, H. & Rajpert-De Meyts, E., 2006, In: Virchows Archiv. 449, 2, p. 200-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Natural history of seminiferous tubule degeneration in Klinefelter syndrome

    Aksglaede, L., Wikström, A. M., Rajpert-De Meyts, E., Dunkel, L., Skakkebæk, Niels Erik & Juul, Anders, 2006, In: Human Reproduction Update. 12, 1, p. 39-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Pubertal development in Danish children: comparison of recent European and US data

    Juul, Anders, Teilmann, Grete Katrine, Scheike, T. H., Hertel, N., Holm, Kirsten, Laursen, E., Main, Katharina Maria & Skakkebæk, Niels Erik, 2006, In: International Journal of Andrology. 29, 1, p. 247-55; discussion 286-90

    Research output: Contribution to journalJournal articleResearchpeer-review

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