Niels Erik Skakkebæk

Niels Erik Skakkebæk

Affiliate Professor

Member of:

  • Paediatrics


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  1. Published

    Early breast development in girls after prenatal exposure to non-persistent pesticides

    Veje, C. W., Andersen, H. R., Schmidt, I. M., Aksglaede, L., Sørensen, K., Juul, Anders, Jensen, T. K., Grandjean, P., Skakkebæk, Niels Erik & Main, Katharina Maria, 2012, In: International Journal of Andrology. 35, 3, p. 273-82

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Early puberty in internationally adopted girls: hormonal and clinical markers of puberty in 276 girls examined biannually over two years

    Teilmann, Grete Katrine, Petersen, Jørgen Holm, Gormsen, M., Damgaard, K., Skakkebæk, Niels Erik, Jensen, T. K., Teilmann, Grete Katrine, Petersen, J. H., Gormsen, M., Damgaard, K., Skakkebæk, Niels Erik & Jensen, T. K., 1 Jan 2009, In: Hormone Research. 72, 4, p. 236-46 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Effects of growth hormone replacement therapy on IGF-related parameters and on the pituitary-gonadal axis in GH-deficient males. A double-blind, placebo-controlled crossover study

    Juul, Anders, Andersson, A. M., Pedersen, S. A., Jørgensen, J. O., Christiansen, J. S., Groome, N. P. & Skakkebæk, Niels Erik, 1998, In: Hormone Research. 49, 6, p. 269-78 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling

    Almstrup, Kristian, Høi-Hansen, Christina Engel, Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jul 2004, In: Cancer Research. 64, 14, p. 4736-4743 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Endocrine Disrupting Chemicals and Risk of Testicular Cancer A Systematic Review and Meta-analysis

    Bräuner, E. V., Lim, Youn-Hee, Koch, T., Uldbjerg, C. S., Gregersen, L. S., Pedersen, M. K., Frederiksen, H., Petersen, Jørgen Holm, Coull, B. A., Andersson, A., Hickey, M., Skakkebæk, Niels Erik, Hauser, R. & Juul, Anders, 2021, In: The Journal of clinical endocrinology and metabolism. 106, 12, p. e4834–e4860 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Endocrine disrupters: we need research, biomonitoring and action

    Andersson, A., Bay, K., Frederiksen, H. & Skakkebæk, Niels Erik, Jul 2016, In: Andrology. 4, 4, p. 556-60 5 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  7. Published

    Endocrine function in patients treated for carcinoma in situ in the testis with irradiation

    Petersen, P. M., Daugaard, G., Rørth, M. & Skakkebæk, Niels Erik, 2003, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 111, 1, p. 93-8; discussion 98-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society

    Zoeller, R. T., Brown, T. R., Doan, L. L., Gore, A. C., Skakkebæk, Niels Erik, Soto, A. M., Woodruff, T. J. & Vom Saal, F. S., 2012, In: Endocrinology. 153, 9, p. 4097-110 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Environment, testicular dysgenesis and carcinoma in situ testis

    Olesen, I. A., Sonne, Si Brask, Hoei-Hansen, C. E., Rajpert-DeMeyts, E. & Skakkebæk, Niels Erik, 2007, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 21, 3, p. 462-78 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Environmental factors and puberty timing: expert panel research needs

    Louis, G. M. B., Jr, L. E. G., Marcus, M., Ojeda, S. R., Pescovitz, O. H., Witchel, S. F., Sippell, W., Abbott, D. H., Soto, A., Tyl, R. W., Bourguignon, J. P., Swan, S. H., Golub, M. S., Wabitsch, M., Toppari, J., Euling, S. Y. & Skakkebæk, Niels Erik, 2008, In: Pediatrics. 121 Suppl 3, p. S192-S207

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Environmental factors in declining human fertility

    Skakkebæk, Niels Erik, Lindahl-Jacobsen, R., Levine, H., Andersson, A., Jørgensen, N., Main, Katharina Maria, Lidegaard, Øjvind, Priskorn, Lærke, Holmboe, S. A., Bräuner, E. V., Almstrup, Kristian, Franca, L. R., Znaor, A., Kortenkamp, A., Hart, R. J. & Juul, Anders, 2022, In: Nature Reviews Endocrinology. 18, p. 139–157

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells

    Kristensen, D. G., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Almstrup, Kristian, 2013, In: International Journal of Developmental Biology. 57, 2-4, p. 309-317 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Erratum: PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men (Human Reproduction (2013) 28 (599-608))

    Joensen, Ulla Nordström, Veyrand, B., Antignac, J. P., Jensen, Martin Blomberg, Petersen, Jørgen Holm, Marchand, P., Skakkebæk, Niels Erik, Andersson, A. M., Le Bizec, B. & Jorgensen, N., 2014, In: Human Reproduction. 29, 7, p. 1600 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  14. Published

    European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part II

    Krege, S., Beyer, J., Souchon, R., Albers, P., Albrecht, W., Algaba, F., Bamberg, M., Bodrogi, I., Bokemeyer, C., Cavallin-Ståhl, E., Classen, J., Clemm, C., Cohn-Cedermark, G., Culine, S., Daugaard, G., De Mulder, P. H. M., De Santis, M., de Wit, M., de Wit, R., Derigs, H. G. & 63 others, Dieckmann, K., Dieing, A., Droz, J., Fenner, M., Fizazi, K., Flechon, A., Fosså, S. D., del Muro, X. G., Gauler, T., Geczi, L., Gerl, A., Germa-Lluch, J. R., Gillessen, S., Hartmann, J. T., Hartmann, M., Heidenreich, A., Hoeltl, W., Horwich, A., Huddart, R., Jewett, M., Joffe, J., Jones, W. G., Kisbenedek, L., Klepp, O., Kliesch, S., Koehrmann, K. U., Kollmannsberger, C., Kuczyk, M., Laguna, P., Galvis, O. L., Loy, V., Mason, M. D., Mead, G. M., Mueller, R., Nichols, C., Nicolai, N., Oliver, T., Ondrus, D., Oosterhof, G. O. N., Paz-Ares, L., Pizzocaro, G., Pont, J., Pottek, T., Powles, T., Rick, O., Rosti, G., Salvioni, R., Scheiderbauer, J., Schmelz, H., Schmidberger, H., Schmoll, H., Schrader, M., Sedlmayer, F., Skakkebæk, Niels Erik, Sohaib, A., Tjulandin, S., Warde, P., Weinknecht, S., Weissbach, L., Wittekind, C., Winter, E., Wood, L. & von der Maase, H., 2007, In: European Urology. 53, 3, p. 497-513 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I

    Krege, S., Beyer, J., Souchon, R., Albers, P., Albrecht, W., Algaba, F., Bamberg, M., Bodrogi, I., Bokemeyer, C., Cavallin-Ståhl, E., Classen, J., Clemm, C., Cohn-Cedermark, G., Culine, S., Daugaard, G., De Mulder, P. H. M., De Santis, M., de Wit, M., de Wit, R., Derigs, H. G. & 63 others, Dieckmann, K., Dieing, A., Droz, J., Fenner, M., Fizazi, K., Flechon, A., Fosså, S. D., del Muro, X. G., Gauler, T., Geczi, L., Gerl, A., Germa-Lluch, J. R., Gillessen, S., Hartmann, J. T., Hartmann, M., Heidenreich, A., Hoeltl, W., Horwich, A., Huddart, R., Jewett, M., Joffe, J., Jones, W. G., Kisbenedek, L., Klepp, O., Kliesch, S., Koehrmann, K. U., Kollmannsberger, C., Kuczyk, M., Laguna, P., Galvis, O. L., Loy, V., Mason, M. D., Mead, G. M., Mueller, R., Nichols, C., Nicolai, N., Oliver, T., Ondrus, D., Oosterhof, G. O. N., Ares, L. P., Pizzocaro, G., Pont, J., Pottek, T., Powles, T., Rick, O., Rosti, G., Salvioni, R., Scheiderbauer, J., Schmelz, H., Schmidberger, H., Schmoll, H., Schrader, M., Sedlmayer, F., Skakkebæk, Niels Erik, Sohaib, A., Tjulandin, S., Warde, P., Weinknecht, S., Weissbach, L., Wittekind, C., Winter, E., Wood, L. & von der Maase, H., 2007, In: European Urology. 53, 3, p. 478-496 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Evidence for decreasing quality of semen during past 50 years

    Carlsen, E., Giwercman, A., Keiding, N. & Skakkebæk, Niels Erik, Mar 1993, In: Obstetrical & Gynecological Survey. 48, 3, p. 200-201 2 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis

    Kristensen, D. G., Nielsen, J. E., Jørgensen, A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Almstrup, Kristian, 4 Feb 2014, In: British Journal of Cancer. 110, 3, p. 668-678 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window

    van den Driesche, S., Kilcoyne, K. R., Wagner, I., Rebourcet, D., Boyle, A., Mitchell, R., McKinnell, C., Macpherson, S., Donat, R., Shukla, C. J., Jorgensen, A., Meyts, E. R., Skakkebæk, Niels Erik & Sharpe, R. M., 2017, In: JCI insight. 2, 6, 20 p., e91204.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Exposure to UV filters during summer and winter in Danish kindergarten children

    Krause, M., Andersson, A., Skakkebæk, Niels Erik & Frederiksen, H., Feb 2017, In: Environment International. 99, p. 177-184 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Exposure to phenols, parabens and UV filters: Associations with loss-of-function mutations in the filaggrin gene in men from the general population

    Joensen, U. N., Jørgensen, N., Thyssen, Jacob Pontoppidan, Petersen, Jørgen Holm, Szecsi, P. B., Stender, S., Andersson, A. M., Skakkebæk, Niels Erik & Frederiksen, H., 2017, In: Environment International. 105, p. 105-111

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Expression of the vitamin D metabolizing enzyme CYP24A1 at the annulus of human spermatozoa may serve as a novel marker of semen quality

    Jensen, Martin Blomberg, Jørgensen, A., Nielsen, Jens Erik Klint, Bjerrum, P. J., Skalkam, M., Petersen, Jørgen Holm, Egeberg, D. L., Bangsbøll, S., Andersen, A. N., Skakkebæk, Niels Erik, Juul, Anders, Rajpert-De Meyts, E., Dissing, Steen, Leffers, H. & Jørgensen, N., 2012, In: International Journal of Andrology. 35, 4, p. 499-510 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Falling sperm quality

    Keiding, N., Giwercman, A., Carlsen, E. & Skakkebæk, Niels Erik, 9 Jul 1994, In: BMJ. 309, 6947, p. 131-131 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  23. Published

    Familial resemblance in markers of testicular function in fathers and their young sons: a cross-sectional study

    Priskorn, L., Joensen, Ulla Nordström, Petersen, Jørgen Holm, Jensen, T. K., Skakkebæk, Niels Erik & Jørgensen, N., 2021, In: Human reproduction (Oxford, England). 36, 3, p. 543-550 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing

    Crain, D. A., Janssen, S. J., Edwards, T. M., Heindel, J., Ho, S., Hunt, P., Iguchi, T., Juul, Anders, McLachlan, J. A., Schwartz, J., Skakkebæk, Niels Erik, Soto, A. M., Swan, S., Walker, C., Woodruff, T. K., Woodruff, T. J., Giudice, L. C. & Guillette, L. J., 2008, In: Fertility and Sterility. 90, 4, p. 911-40 30 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general population

    Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Mar 2007, In: American Journal of Epidemiology. 165, 5, p. 583-90 8 p.

    Research output: Contribution to journal › Journal article › Research

  26. Published

    Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm

    Birch, M. R., Dissing, Steen, Skakkebæk, Niels Erik & Rehfeld, Anders Aagaard, 2021, In: Reproduction. 161, 5, p. 561-572 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Free insulin-like growth factor I serum levels in 1430 healthy children and adults, and its diagnostic value in patients suspected of growth hormone deficiency

    Juul, Anders, Holm, Kirsten, Kastrup, K. W., Pedersen, S. A., Michaelsen, K. F., Scheike, T. H., Rasmussen, S., Müller, J. & Skakkebæk, Niels Erik, 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 8, p. 2497-502 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Free testosterone and cardiometabolic parameters in men: Comparison of algorithms

    Holmboe, S. A., Jasuja, R., Lawney, B., Priskorn, L., Joergensen, N., Linneberg, Allan René, Jensen, T. K., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A. M., 2021, In: Endocrine Connections. 10, 2, p. 220-229 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    From embryonic stem cells to testicular germ cell cancer-- should we be concerned?

    Almstrup, Kristian, Sonne, Si Brask, Hoei-Hansen, C. E., Ottesen, A. M., Nielsen, J. E., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: International Journal of Andrology. 29, 1, p. 211-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    GH-deficiency, sweating and thermoregulations

    Juul, Anders, Main, Katharina Maria, Hjortskov, N., Jepsen, L., Nielsen, B., Halkjær-Kristensen, J. & Skakkebæk, Niels Erik, 1996, Growth Hormone in adults; Physiological and clinical aspects. p. 246 5 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  31. Published

    Gene expression profiles of mouse spermatogenesis during recovery from irradiation

    Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H., Almstrup, K., Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H. & Almstrup, Kristian, 1 Jan 2009, In: Reproductive Biology and Endocrinology. 7, p. 130

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Genetic variations in FSH action affect sex hormone levels and breast tissue size in infant girls: A pilot study

    Henriksen, L. S., Hagen, C. P., Assens, M., Busch, A. S., Skakkebæk, Niels Erik, Almstrup, K. & Main, Katharina Maria, 1 Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3191-3198 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Genital anomalies in boys and the environment

    Main, Katharina Maria, Skakkebæk, Niels Erik, Virtanen, H. E. & Toppari, J., 1 Apr 2010, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 24, 2, p. 279-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer

    Edsgärd, D., Dalgaard, M. D., Weinhold, N., Wesolowska-Andersen, A., Rajpert-De Meyts, E., Ottesen, A. M., Juul, Anders, Skakkebæk, Niels Erik, Skøt Jensen, T., Gupta, R., Leffers, H. & Brunak, S., 2013, In: Frontiers in Endocrinology. 4, p. 2

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours

    Almstrup, Kristian, Høi-Hansen, Christina Engel, Nielsen, J. E., Wirkner, U., Ansorge, W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 23 May 2005, In: British Journal of Cancer. 92, 10, p. 1934-1941 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ

    Almstrup, Kristian, Ottesen, A. M., Sonne, Si Brask, Hoei-Hansen, C. E., Leffers, H., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 2005, In: Cell and Tissue Research. 322, 1, p. 159-65 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Germ cell differentiation-dependent and stage-specific expression of LANCL1 in rodent testis

    Nielsen, J. E., Hansen, M. A., Jørgensen, M., Tanaka, M., Almstrup, Kristian, Skakkebæk, Niels Erik & Leffers, H., 2003, In: European Journal of Histochemistry. 47, 3, p. 215-222 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Germ cell neoplasia in situ (GCNIS): evolution of the current nomenclature for testicular pre-invasive germ cell malignancy

    Berney, D. M., Looijenga, L. H. J., Idrees, M., Oosterhuis, J. W., Rajpert-De Meyts, E., Ulbright, T. M. & Skakkebæk, Niels Erik, Jul 2016, In: Histopathology. 69, 1, p. 7-10 4 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Germ cell neoplasia in situ and preserved fertility despite suppressed gonadotropins in a patient with testotoxicosis

    Mortensen, L. J., Jensen, M. B., Christiansen, P., Rønholt, A. M., Jørgensen, A., Frederiksen, H., Nielsen, J. E., Loya, Anand Chainsukh, Grønkær Toft, B., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Juul, Anders, 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 12, p. 4411-4416 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Global patterns in testicular cancer incidence and mortality in 2020

    Znaor, A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Kuliš, T., Laversanne, M., Gurney, J., Sarfati, D., McGlynn, K. A. & Bray, F., 2022, In: International Journal of Cancer. 151, 5, p. 692-698 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Goodbye International Journal of Andrology, welcome Andrology!

    Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2012, In: International Journal of Andrology. 36, 6, p. 769-774 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Goodbye International Journal of Andrology, welcome Andrology!

    Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2022, In: Andrology. 10, S2, p. 133-138

    Research output: Contribution to journal › Editorial › Research › peer-review

  43. Published

    Growth hormone (GH) provocative retesting of 108 young adults with childhood-onset GH deficiency and the diagnostic value of insulin-like growth factor I (IGF-I) and IGF-binding protein-3

    Juul, Anders, Kastrup, K. W., Pedersen, S. A. & Skakkebæk, Niels Erik, 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 4, p. 1195-201 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Growth hormone (GH) treatment increases serum insulin-like growth factor binding protein-3, bone isoenzyme alkaline phosphatase and forearm bone mineral content in young adults with GH deficiency of childhood onset

    Juul, Anders, Pedersen, S. A., Sørensen, S., Winkler, K., Jørgensen, J. O., Christiansen, J. S. & Skakkebæk, Niels Erik, 1994, In: European Journal of Endocrinology. 131, 1, p. 41-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Growth hormone (GH), exercise performance, muscle strength and sweat production in healthy subjects and adults with GH deficiency

    Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 2000, Growth Hormone in adults; Physiological and clinical aspects. 2 ed. p. 281-300 19 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  46. Published

    Growth hormone (GH)-deficiency in adults: clinical features and effects of GH substitution.

    Jørgensen, J., Møller, J., Wolthers, T., Vahn, N., Juul, Anders, Skakkebæk, Niels Erik & Christiansen, J., 1994, In: The journal of pediatric endocrinology. p. 283-293 10 p.

    Research output: Contribution to journal › Journal article › Research

  47. Published

    Growth hormone deficiency and hyperthermia

    Juul, Anders & Skakkebæk, Niels Erik, 1991, In: Lancet. 338, 8771, p. 887

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Growth hormone deficiency and hyperthermia during exercise: a controlled study of sixteen GH-deficient patients

    Juul, Anders, Hjortskov, N., Jepsen, L., Nielsen, B., Halkjaer-Kristensen, J., Vahl, N., Jørgensen, J. O., Christiansen, J. S. & Skakkebæk, Niels Erik, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 11, p. 3335-40 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Growth hormone treatment during pregnancy in a growth hormone-deficient woman

    Müller, J., Starup, J., Christiansen, J. S., Jørgensen, J. O., Juul, Anders & Skakkebæk, Niels Erik, 1995, In: European Journal of Endocrinology. 132, 6, p. 727-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Growth hormone treatment in GH-deficient adults; therapeutic and diagnostic aspects.

    Juul, Anders, Jørgensen, J., müller, J. & Skakkebæk, Niels Erik, 1994, In: Clinical Pediatric Endocrinology. p. 63-71 8 p.

    Research output: Contribution to journal › Review › Research

  51. Published

    Growth hormone treatment of non-elderly adults with GH-deficiency

    Christiansen, J., Jørgensen, J., Vahn, N., Juul, Anders, Müller, J. & Skakkebæk, Niels Erik, 1995, GHRH, GH and IGF-1: Basic and clinical Advances. p. 169-175 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  52. Published

    Growth hormone, insulin-like growth factor I and its binding proteins 1 and 3 in last trimester intrauterine growth retardation with increased pulsatility index in the umbilical artery

    Larsen, T., Main, Katharina Maria, Andersson, A. M., Juul, Anders, Greisen, Gorm & Skakkebæk, Niels Erik, 1996, In: Clinical Endocrinology. 45, 3, p. 315-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Habitual alcohol consumption associated with reduced semen quality and changes in reproductive hormones; a cross-sectional study among 1221 young Danish men

    Jensen, T. K., Gottschau, M., Madsen, J. O. B., Andersson, A., Lassen, T. H., Skakkebæk, Niels Erik, Swan, S. H., Priskorn, L., Juul, Anders & Jørgensen, N., 2014, In: B M J Open. 4, 9, p. 1-11 11 p., e005462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information

    Edsgärd, D., Scheel, M., Hansen, N. T., Ralfkiaer, U., Jensen, T. S., Skakkebæk, Niels Erik, Brunak, S., Gupta, R., Rajpert-De Meyts, E. & Ottesen, A. M., 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e122-32

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    High maternal age at first and subsequent child births in Denmark in the mid-1800s-Letter to the editor

    Priskorn, L., Dahl, C. L., Pihl, A. S., Skakkebæk, Niels Erik & Juul, Anders, Oct 2019, In: European Journal of Obstetrics & Gynecology and Reproductive Biology. 241, p. 137-138 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  56. Published

    High normal testosterone levels in infants with non-mosaic Klinefelter's syndrome

    Aksglaede, L., Petersen, Jørgen Holm, Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2007, In: European Journal of Endocrinology. 157, 3, p. 345-50 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer

    Hoei-Hansen, C. E., Holm, M., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Jul 2003, In: Journal of Pathology. 200, 3, p. 370-4 5 p.

    Research output: Contribution to journal › Journal article › Research

  58. Published

    Histopathological Evaluation of Testicular Biopsy

    Rajpert-de Meyts, E., Grigor, K. M. & Skakkebæk, Niels Erik, 2017, Endocrinology of the Testis and Male Reproduction. SimoniIlpo, M. & Huhtaniemi, I. (eds.). p. 1-20 (Endocrinology of the Testis and Male Reproduction).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  59. Published

    Hormonal changes during GnRH analogue therapy in children with central precocious puberty

    Müller, J., Juul, Anders, Andersson, A. M., Sehested, A. & Skakkebæk, Niels Erik, 2000, In: Journal of Pediatric Endocrinology and Metabolism. 13 Suppl 1, p. 739-46 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age

    Main, Katharina Maria, Mortensen, G. K., Kaleva, M. M., Boisen, K. A., Damgaard, I. N., Chellakooty, M., Schmidt, I. M., Suomi, A., Virtanen, H. E., Petersen, J. H., Andersson, A., Toppari, J. & Skakkebæk, Niels Erik, 2006, In: Environmental Health Perspectives. 114, 2, p. 270-276 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men

    Jørgensen, N., Joensen, Ulla Nordström, Jensen, T., Jensen, M., Almstrup, Kristian, Olesen, I., Juul, A., Andersson, A., Carlsen, E., Petersen, Jørgen Holm, Toppari, J. & Skakkebæk, Niels Erik, 2012, In: B M J Open. 2, 4, e000990.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism

    Rehfeld, Anders Aagaard, Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, Anders, Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Human urinary excretion of non-persistent environmental chemicals: an overview of Danish data collected between 2006 and 2012

    Frederiksen, H., Jensen, T. K., Jørgensen, N., Kyhl, H. B., Husby, S., Skakkebæk, Niels Erik, Main, Katharina Maria, Juul, Anders & Andersson, A., 2014, In: Reproduction. 147, 4, p. 555-565 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Hypothesis: Metformin is a potential reproductive toxicant

    Tavlo, M., Skakkebæk, Niels Erik, Mathiesen, Elisabeth, Kristensen, D. M., Kjær, Kurt H., Andersson, A. & Lindahl-Jacobsen, R., 2022, In: Frontiers in Endocrinology. 13, 8 p., 1000872.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Hypothesis: exposure to endocrine-disrupting chemicals may interfere with timing of puberty

    Mouritsen, Annette Korsholm, Aksglaede, L., Sørensen, K., Mogensen, S. S., Leffers, H., Main, Katharina Maria, Frederiksen, H., Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 346-59 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Identification and expression profiling of 10 novel spermatid expressed CYPT genes

    Hansen, M. A., Nielsen, J. E., Tanaka, M., Almstrup, Kristian, Skakkebæk, Niels Erik & Leffers, H., May 2006, In: Molecular Reproduction and Development. 73, 5, p. 568-579 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Identification of genes differentially expressed in testes containing carcinoma in situ

    Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-DeMeyts, E. & Leffers, H., Jun 2004, In: Molecular Human Reproduction. 10, 6, p. 423-431 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours

    Sonne, Si Brask, Herlihy, A. S., Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, Kristian, Skakkebæk, Niels Erik, Marks, A., Leffers, H. & Rajpert-De Meyts, E., 2006, In: Virchows Archiv. 449, 2, p. 200-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Immunohistochemical expression of embryonal marker TRA-1-60 in carcinoma in situ and germ cell tumors of the testis

    Giwercman, A., Andrews, P. W., Jørgensen, N., Müller, J., Graem, N. & Skakkebæk, Niels Erik, 15 Aug 1993, In: Cancer. 72, 4, p. 1308-14 7 p.

    Research output: Contribution to journal › Journal article › Research

  70. Published

    Impact of growth hormone administration on other hormonal axes.

    Jørgensen, J., Ovesen, P., Juul, Anders, Hansen, T., Skakkebæk, Niels Erik & Christiansen, J., 1999, In: Hormone Research. 51, p. 121-126 5 p.

    Research output: Contribution to journal › Review › Research

  71. Published

    Impact of psychological stress measured in three different scales on testis function: A cross-sectional study of 1362 young men

    Nordkap, L., Priskorn, L., Bräuner, E. V., Hansen, Åse Marie, Kirstine Bang, A., Holmboe, S. A., Winge, S. B., Egeberg Palme, D. L., Mørup, N., Skakkebæk, Niels Erik, Kold Jensen, T. & Jørgensen, N., 2020, In: Andrology. 8, 6, p. 1674-1686 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Impaired testicular function in patients with carcinoma-in-situ of the testis

    Petersen, P. M., Giwercman, A., Hansen, S. W., Berthelsen, Jens, Daugaard, G., Rørth, M. & Skakkebæk, Niels Erik, 1999, In: Journal of Clinical Oncology. 17, 1, p. 173-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Impaired thermoregulation in adults with growth hormone deficiency during heat exposure and exercise

    Juul, Anders, Behrenscheer, A., Tims, T., Nielsen, B., Halkjaer-Kristensen, J. & Skakkebæk, Niels Erik, 1993, In: Clinical Endocrinology. 38, 3, p. 237-244 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Improved gene expression signature of testicular carcinoma in situ

    Almstrup, Kristian, Leffers, H., Lothe, R. A., Skakkebæk, Niels Erik, Sonne, Si Brask, Nielsen, J. E., Rajpert-De Meyts, E. & Skotheim, R. I., 2007, In: International Journal of Andrology. 30, 4, p. 292-303

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Increase in first morning voided urinary luteinizing hormone levels precedes the physical onset of puberty

    Demir, A., Voutilainen, R., Juul, Anders, Dunkel, L., Alfthan, H., Skakkebæk, Niels Erik & Stenman, U. H., 1996, In: Journal of Clinical Endocrinology and Metabolism. 81, 8, p. 2963-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Increase in maternal placental growth hormone during pregnancy and disappearance during parturition in normal and growth hormone-deficient pregnancies

    Lønberg, U., Damm, Peter, Andersson, A., Main, Katharina Maria, Chellakooty, M., Lauenborg, J., Skakkebæk, Niels Erik & Juul, Anders, 1 Jan 2003, In: American Journal of Obstetrics and Gynecology. 188, 1, p. 247-51 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Increased expression of alpha- and beta-globin mRNAs at the pituitary following exposure to estrogen during the critical period of neonatal sex differentiation in the rat

    Leffers, H., Navarro, V. M., Nielsen, J. E., Mayen, A., Pinilla, L., Dalgaard, M., Malagon, M. M., Castaño, J. P., Skakkebæk, Niels Erik, Aguilar, E. & Tena-Sempere, M., 1 Apr 2006, In: Journal of Steroid Biochemistry and Molecular Biology. 99, 1, p. 33-43 11 p.

    Research output: Contribution to journal › Journal article › Research

  78. Published

    Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle

    Holm, M., Hoei-Hansen, C. E., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Oct 2003, In: Journal of Urology. 170, 4 Pt 1, p. 1163-7 5 p.

    Research output: Contribution to journal › Journal article › Research

  79. Published

    Increasing international efforts to understand and conquer testicular germ cell cancer

    Rajpert-De Meyts, E., Daugaard, G., Almstrup, Kristian, Jørgensen, A., Rørth, M., Jørgensen, N., von der Maase, H. & Skakkebæk, Niels Erik, Jan 2015, In: Andrology. 3, 1, p. 1-3 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  80. Published

    Increasing trends in childlessness in recent birth cohorts - a registry-based study of the total Danish male population born from 1945 to 1980

    Priskorn, L., Holmboe, S., Jacobsen, R., Jensen, T. K., Lassen, T. H. & Skakkebæk, Niels Erik, 2012, In: International Journal of Andrology. 35, 3, p. 449-55 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Individual testosterone decline and future mortality risk in men

    Holmboe, S. A., Skakkebæk, Niels Erik, Juul, Anders, Scheike, Thomas, Jensen, T. K., Linneberg, Allan René, Thuesen, B. H. & Andersson, A., Jan 2018, In: European Journal of Endocrinology. 178, p. 121-128

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects

    Hansen, Lasse Bøllehuus, Kaludjerovic, J., Nielsen, J. E., Rehfeld, Anders Aagaard, Poulsen, N. N., Ide, N., Skakkebæk, Niels Erik, Frederiksen, H., Juul, Anders, Lanske, B. & Jensen, M. B., 2020, In: F A S E B Journal. 34, 9, p. 12436-12449

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Influence of marital status on testosterone levels-A ten year follow-up of 1113 men

    Holmboe, S. A., Priskorn, L., Jørgensen, N., Skakkebæk, Niels Erik, Linneberg, Allan René, Juul, Anders & Andersson, A., 2017, In: Psychoneuroendocrinology. 80, p. 155-161 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls

    Chellakooty, M., Schmidt, I. M., Haavisto, A. M., Boisen, K. A., Damgaard, I. N., Mau, C., Petersen, Jørgen Holm, Juul, Anders, Skakkebæk, Niels Erik & Main, Katharina Maria, 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 8, p. 3515-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism

    Bay, K., Virtanen, H. E., Hartung, S., Ivell, R., Main, Katharina Maria, Skakkebæk, Niels Erik, Andersson, A., Toppari, J. & Nordic Cryptorchidism Study Group, N. C. S. G., 1 Oct 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 4020-7 8 p.

    Research output: Contribution to journal › Journal article › Research

  86. Published

    Insulin-like factor 3 levels in second-trimester amniotic fluid

    Bay, K., Cohen, A. S., Jørgensen, Finn Stener, Jørgensen, C., Lind, A. M., Skakkebæk, Niels Erik & Andersson, A., 1 Oct 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4048-51 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Insulin-like growth factor I (IGF-I) and IGF-binding protein 3 as diagnostic markers of growth hormone deficiency in infancy

    Jensen, R. B., Jeppesen, K. A., Vielwerth, S., Michaelsen, K. F., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Hormone Research. 63, 1, p. 15-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Intranasal LH-RH treatment of cryptorchidism. A clinical trial and 5 years follow-up

    Thorup, Jørgen Mogens, Mauritzen, K. & Skakkebæk, Niels Erik, 1987, In: European Journal of Pediatrics. 146 Suppl 2, p. S40-1

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Intranasalt gonadotropinfrigørende hormon (LH-RH) som behandling ved retentio testis

    Bertelsen, A., Skakkebæk, Niels Erik, Mauritzen, K., Preuss, P., Pedersen, P. V. & Thorup, Jørgen Mogens, 15 Jun 1981, In: Ugeskrift for Laeger. 143, 25, p. 1595-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

    Kristensen, D. M., Hass, U., Lesné, L., Lottrup, G., Jacobsen, P. R., Desdoits-Lethimonier, C., Boberg, J., Petersen, Jørgen Holm, Toppari, J., Jensen, T. K., Brunak, Søren, Skakkebæk, Niels Erik, Nellemann, C., Main, Katharina Maria, Jégou, B. & Leffers, H., 2011, In: Human Reproduction. 26, 1, p. 235-44 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: does insulin-like growth factor-I play a role?

    Jensen, R. B. B., Chellakooty, M., Vielwerth, S., Vaag, Allan, Larsen, T. K., Greisen, Gorm, Skakkebæk, Niels Erik, Scheike, T. H. & Juul, Anders, 2003, In: Hormone Research. 60 Suppl 3, p. 136-48 13 p.

    Research output: Contribution to journal › Journal article › Research

  92. Published

    In vitro bioassay investigations of the endocrine disrupting potential of steviol glycosides and their metabolite steviol, components of the natural sweetener Stevia

    Shannon, M., Rehfeld, Anders Aagaard, Frizzell, C., Livingstone, C., McGonagle, C., Skakkebæk, Niels Erik, Wielogórska, E. & Connolly, L., 15 May 2016, In: Molecular and Cellular Endocrinology. 427, p. 65-72

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Is Sedentary Lifestyle Associated With Testicular Function? A Cross-Sectional Study of 1,210 Men

    Priskorn, L., Jensen, T. K., Bang, A. K., Nordkap, L., Joensen, Ulla Nordström, Lassen, T. H., Olesen, I. A., Swan, S. H., Skakkebæk, Niels Erik & Jørgensen, N., 15 Aug 2016, In: American Journal of Epidemiology. 184, 4, p. 284-294 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Is human fecundity changing? A discussion of research and data gaps precluding us from having an answer

    Smarr, M. M., Sapra, K. J., Gemmill, A., Kahn, L. G., Wise, L. A., Lynch, C. D., Factor-Litvak, P., Mumford, S. L., Skakkebæk, Niels Erik, Slama, R., Lobdell, D. T., Stanford, J. B., Jensen, T. K., Boyle, E. H., Eisenberg, M. L., Turek, P. J., Sundaram, R., Thoma, M. E. & Buck Louis, G. M., 2017, In: Human Reproduction. 32, 3, p. 499-504

    Research output: Contribution to journal › Comment/debate › Research

  95. Published

    Is human fecundity declining?

    Skakkebæk, Niels Erik, Jørgensen, N., Main, Katharina Maria, Rajpert-De Meyts, E., Leffers, H., Andersson, A., Juul, Anders, Carlsen, E., Mortensen, G. K., Jensen, T. K. & Toppari, J., 1 Feb 2006, In: International Journal of Andrology. 29, 1, p. 2-11 10 p.

    Research output: Contribution to journal › Journal article › Research

  96. Published

    Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?

    Bang, A. K., Busch, A. S., Almstrup, Kristian, Gromoll, J., Kliesch, S., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders, Tüttelmann, F. & Jørgensen, N., 2018, In: Andrology. 6, 1, p. 176-183 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Is there a problem with male reproduction?

    Joensen, Ulla Nordström, Skakkebæk, Niels Erik & Jørgensen, N., 2009, In: Nature Clinical Practice Endocrinology & Metabolism. 5, 3, p. 144-5 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity

    Belling, K., Russo, F., Jensen, A. B., Dalgaard, M. D., Westergaard, David, Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders & Brunak, Søren, 1 Apr 2017, In: Human Molecular Genetics. 26, 7, p. 1219-1229 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Klinefelter syndrome: the forgotten syndrome: basic and clinical questions posed to an international group of scientists

    Juul, Anders, Aksglaede, L., Bay, K., Grigor, K. M. & Skakkebæk, Niels Erik, 1 Jun 2011, In: Acta Paediatrica. 100, 6, p. 791-2 2 p.

    Research output: Contribution to journal › Conference article › Research

  100. Published

    Lack of stimulation of 24-hour growth hormone release by hypocaloric diet in obesity

    Rasmussen, M. H., Juul, Anders, Kjems, L. L., Skakkebæk, Niels Erik & Hilsted, J., 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 3, p. 796-801 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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