Niels Erik Skakkebæk
Affiliate Professor
- 2024
- Published
The epidemiology of cryptorchidism and potential risk factors, including endocrine disrupting chemicals
Holmboe, S. A., Beck, A. L., Andersson, A. M., Main, Katharina Maria, Jørgensen, N., Skakkebæk, Niels Erik & Priskorn, L., 2024, In: Frontiers in Endocrinology. 15, 8 p., 1343887.Research output: Contribution to journal › Review › Research › peer-review
- Published
Time to pregnancy and life expectancy: a cohort study of 18796 pregnant couples
Lindahl-Jacobsen, R., Petersson, M. T., Priskorn, Lærke, Skakkebæk, Niels Erik, Juul, Anders, Kristensen, D. M., Eisenberg, M. L. & Jensen, T. K., 2024, In: Human Reproduction. 39, 3, p. 595-603 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Cotinine concentrations in maternal serum and amniotic fluid during pregnancy and risk of testicular germ cell cancer in the offspring: A prospective nested case-control study
Beck, A. L., Uldbjerg, C. S., Lim, Youn-Hee, Coull, B. A., Sørensen, K. M., Utko, M. M., Wilkowski, B., Rantakokko, P., Bengtsson, M., Lindh, C., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Hauser, R., Juul, Anders & Bräuner, E. V., 2023, In: International Journal of Cancer. 154, 1, p. 71-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pituitary–gonadal hormones associated with respiratory failure in men and women hospitalized with COVID-19: an observational cohort study
Clausen, C. L., Johannsen, T. H., Skakkebæk, Niels Erik, Frederiksen, H., Ryrsø, C. K., Dungu, A. M., Hegelund, M. H., Faurholt-Jepsen, D., Krogh-Madsen, Rikke, Lindegaard, Birgitte, Linneberg, Allan René, Kårhus, L. L., Juul, Anders & Benfield, Thomas, 2023, In: Endocrine Connections. 12, 1, e220444.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal phthalate exposure during pregnancy and testis function of young adult sons
Henriksen, L. S., Frederiksen, H., Jørgensen, N., Juul, Anders, Skakkebæk, Niels Erik, Toppari, J., Petersen, Jørgen Holm & Main, Katharina Maria, 2023, In: Science of the Total Environment. 871, 12 p., 161914.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels of persistent organic pollutants in breast milk samples representing Finnish and Danish boys with and without hypospadias
Tysman, M., Toppari, J., Main, Katharina Maria, Adamsson, A., Wohlfahrt-Veje, C., Antignac, J., Le Bizec, B., Löyttyniemi, E., Skakkebæk, Niels Erik & Virtanen, H. E., 2023, In: Chemosphere. 313, 8 p., 137343.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Paracetamol Use During Pregnancy - A Call for Precautionary Action
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2022, In: Obstetrical and Gynecological Survey. 77, 3, p. 133-134 2 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Reply to ‘Paracetamol use in pregnancy — caution over causal inference from available data’; ‘Handle with care — interpretation, synthesis and dissemination of data on paracetamol in pregnancy’
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., M. Andrade, A., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 3, p. 192 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Reply to ‘Paracetamol use in pregnancy — neglecting context promotes misinterpretation’
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 1 p., 386.Research output: Contribution to journal › Letter › Research › peer-review
- Published
In vitro investigation of endocrine disrupting effects of pesticides on Ca2+-signaling in human sperm cells through actions on the sperm-specific and steroid-activated CatSper Ca2+-channel
Birch, Michala Rosa, Johansen, M., Skakkebæk, Niels Erik, Andersson, A. & Rehfeld, Anders Aagaard, 2022, In: Environment International. 167, 15 p., 107399.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology
Björndahl, L., Barratt, C. L. R., Mortimer, D., Agarwal, A., Aitken, R. J., Alvarez, J. G., Aneck-Hahn, N., Arver, S., Baldi, E., Bassas, L., Boitrelle, F., Bornman, R., Carrell, D. T., Castilla, J. A., Cerezo Parra, G., Check, J. H., Cuasnicu, P. S., Darney, S. P., de Jager, C., De Jonge, C. J. & 67 others, , 2022, In: Human Reproduction. 37, 11, p. 2497-2502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parental occupational exposures in wood-related jobs and risk of testicular germ cell tumours in offspring in NORD-TEST a registry-based case–control study in Finland, Norway, and Sweden
Corbin, S., Togawa, K., Schüz, J., Le Cornet, C., Fervers, B., Feychting, M., Wiebert, P., Hansen, J., Dalton, Susanne Oksbjerg, Kjærheim, K., Nordby, K. C., Østrem, R. S., Skakkebæk, Niels Erik, Uuksulainen, S., Pukkala, E. & Olsson, A., 2022, In: International Archives of Occupational and Environmental Health. 95, p. 1243–1253Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposure to phenols and benzophenones in relation to markers of male reproductive function in adulthood
Holmboe, S. A., Scheutz Henriksen, L., Frederiksen, H., Andersson, A. M., Priskorn, Lærke, Jørgensen, N., Juul, Anders, Toppari, J., Skakkebæk, Niels Erik & Main, Katharina Maria, 2022, In: Frontiers in Endocrinology. 13, 1071761.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Goodbye International Journal of Andrology, welcome Andrology!
Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2022, In: Andrology. 10, S2, p. 133-138Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Optimised detection of germ cell neoplasia in situ in contralateral biopsy reduces the risk of second testis cancer
Rajpert-De Meyts, E., Jørgensen, N., Petersen, Jørgen Holm, Almstrup, Kristian, Aksglaede, L., Lauritsen, J., Rørth, M., Daugaard, G. & Skakkebæk, Niels Erik, 2022, In: BJU International. 130, 5, p. 646-654 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism
Rehfeld, Anders Aagaard, Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, Anders, Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reproductive Markers of Testicular Function and Size During Puberty in Boys With and Without a History of Cryptorchidism
Rodprasert, W., Koskenniemi, J. J., Virtanen, H. E., Sadov, S., Perheentupa, A., Ollila, H., Albrethsen, J., Andersson, A., Juul, Anders, Skakkebæk, Niels Erik, Main, Katharina Maria & Toppari, J., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 12, p. 3353-3361 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum testosterone levels in three-month-old boys predict their semen quality as young adults
Scheutz Henriksen, L., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Jørgensen, N., Virtanen, H. E., Priskorn, Lærke, Juul, Anders, Toppari, J. & Main, Katharina Maria, 2022, In: The Journal of clinical endocrinology and metabolism. 107, 7, p. 1965–1975 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Environmental factors in declining human fertility
Skakkebæk, Niels Erik, Lindahl-Jacobsen, R., Levine, H., Andersson, A., Jørgensen, N., Main, Katharina Maria, Lidegaard, Øjvind, Priskorn, Lærke, Holmboe, S. A., Bräuner, E. V., Almstrup, Kristian, Franca, L. R., Znaor, A., Kortenkamp, A., Hart, R. J. & Juul, Anders, 2022, In: Nature Reviews Endocrinology. 18, p. 139–157Research output: Contribution to journal › Review › Research › peer-review
- Published
Hypothesis: Metformin is a potential reproductive toxicant
Tavlo, M., Skakkebæk, Niels Erik, Mathiesen, Elisabeth, Kristensen, D. M., Kjær, Kurt H., Andersson, A. & Lindahl-Jacobsen, R., 2022, In: Frontiers in Endocrinology. 13, 8 p., 1000872.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nervous system drugs taken by future fathers and birth defects in offspring: a prospective registry-based cohort study
Wensink, M., Lu, Y., Tian, L., Jensen, T. K., Skakkebæk, Niels Erik, Lindahl-Jacobsen, R. & Eisenberg, M., 2022, In: BMJ Open. 12, 3, 8 p., e053946.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study
Wensink, M. J., Lu, Y., Tian, L., Shaw, G. M., Rizzi, S., Jensen, T. K., Mathiesen, Elisabeth, Skakkebæk, Niels Erik, Lindahl-Jacobsen, R. & Eisenberg, M. L., 2022, In: Annals of Internal Medicine. 175, 5, p. 665-673 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global patterns in testicular cancer incidence and mortality in 2020
Znaor, A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Kuliš, T., Laversanne, M., Gurney, J., Sarfati, D., McGlynn, K. A. & Bray, F., 2022, In: International Journal of Cancer. 151, 5, p. 692-698 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Paracetamol use during pregnancy — a call for precautionary action
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2021, In: Nature Reviews Endocrinology. 17, p. 757–766 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm
Birch, M. R., Dissing, Steen, Skakkebæk, Niels Erik & Rehfeld, Anders Aagaard, 2021, In: Reproduction. 161, 5, p. 561-572 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endocrine Disrupting Chemicals and Risk of Testicular Cancer A Systematic Review and Meta-analysis
Bräuner, E. V., Lim, Youn-Hee, Koch, T., Uldbjerg, C. S., Gregersen, L. S., Pedersen, M. K., Frederiksen, H., Petersen, Jørgen Holm, Coull, B. A., Andersson, A., Hickey, M., Skakkebæk, Niels Erik, Hauser, R. & Juul, Anders, 2021, In: The Journal of clinical endocrinology and metabolism. 106, 12, p. e4834–e4860 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid function in covid-19 and the association with cytokine levels and mortality
Clausen, C. L., Rasmussen, Å. K., Johannsen, T. H., Hilsted, Linda, Skakkebæk, Niels Erik, Szecsi, P. B., Pedersen, L., Benfield, Thomas & Juul, Anders, 2021, In: Endocrine Connections. 10, 10, p. 1234-1242 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV filters in matched seminal fluid-, urine-, and serum samples from young men
Frederiksen, H., Krause, M., Jørgensen, N., Rehfeld, Anders Aagaard, Skakkebæk, Niels Erik & Andersson, A., 2021, In: Journal of Exposure Science and Environmental Epidemiology. 31, p. 345–355Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reproductive hormone levels in Minipuberty as a predictor of Testicular Endocrine Function and Penile Length in Healthy Young Men: An 18-year longitudinal Cohort Study
Henriksen, L. S., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Jørgensen, N., Virtanen, H. E., Juul, Anders, Toppari, J. & Main, Katharina Maria, 2021, In: Hormone Research in Paediatrics. 94, SUPPL 1, p. 41-42 2 p., FC5.4.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Free testosterone and cardiometabolic parameters in men: Comparison of algorithms
Holmboe, S. A., Jasuja, R., Lawney, B., Priskorn, L., Joergensen, N., Linneberg, Allan René, Jensen, T. K., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A. M., 2021, In: Endocrine Connections. 10, 2, p. 220-229 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant PNLDC1, Defective piRNA Processing, and Azoospermia
Nagirnaja, L., Mørup, N., Nielsen, J. E., Stakaitis, R., Golubickaite, I., Oud, M. S., Winge, S. B., Carvalho, F., Aston, K. I., Khani, F., Van Der Heijden, G. W., Marques, C. J., Skakkebæk, Niels Erik, Rajpert–de Meyts, E., Schlegel, P. N., Jørgensen, N., Veltman, J. A., Lopes, A. M., Conrad, D. F. & Almstrup, Kristian, 19 Aug 2021, In: New England Journal of Medicine. 385, 8, p. 707-719 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial resemblance in markers of testicular function in fathers and their young sons: a cross-sectional study
Priskorn, L., Joensen, Ulla Nordström, Petersen, Jørgen Holm, Jensen, T. K., Skakkebæk, Niels Erik & Jørgensen, N., 2021, In: Human reproduction (Oxford, England). 36, 3, p. 543-550 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antidepressant Sertraline inhibits CatSper Ca2+channels in human sperm
Rahban, R., Rehfeld, Anders Aagaard, Schiffer, C., Brenker, C., Egeberg Palme, D. L., Wang, T., Lorenz, J., Almstrup, Kristian, Skakkebæk, Niels Erik, Strünker, T. & Nef, S., 2021, In: Human Reproduction. 36, 10, p. 2638-2648Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pubarche and Gonadarche Onset and Progression Are Differently Associated with Birth Weight and Infancy Growth Patterns
Wohlfahrt-Veje, C., Tinggaard, J., Juul, Anders, Toppari, J., Skakkebæk, Niels Erik & Main, Katharina Maria, 1 Aug 2021, In: Journal of the Endocrine Society. 5, 8, 14 p., bvab108.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Bone mineral density is preserved in men with idiopathic infertility
Antonio, L., Priskorn, L., Nordkap, L., Bang, A. K., Jensen, T. K., Skakkebæk, Niels Erik, Petersen, Jørgen Holm, Vanderschueren, D. & Jørgensen, N., 2020, In: Andrology. 8, 2, p. 315-322 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects
Hansen, Lasse Bøllehuus, Kaludjerovic, J., Nielsen, J. E., Rehfeld, Anders Aagaard, Poulsen, N. N., Ide, N., Skakkebæk, Niels Erik, Frederiksen, H., Juul, Anders, Lanske, B. & Jensen, M. B., 2020, In: F A S E B Journal. 34, 9, p. 12436-12449Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men: 2009–2017
Frederiksen, H., Nielsen, O., Koch, H. M., Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Andersson, A. M., Jan 2020, In: International Journal of Hygiene and Environmental Health. 223, 1, p. 93-105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates
Henriksen, L. S., Mathiesen, B. K., Assens, M., Krause, M., Skakkebæk, Niels Erik, Juul, Anders, Andersson, A. M., Hart, R. J., Newnham, J. P., Keelan, J. A., Pennell, C., Main, Katharina Maria & Frederiksen, H., 2020, In: Environmental Research. 184, 109231.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of e-cigarettes associated with lower sperm counts in a cross-sectional study of young men from the general population
Holmboe, S. A., Priskorn, L., Jensen, T. K., Skakkebæk, Niels Erik, Andersson, A. & Jørgensen, N., Jul 2020, In: Human Reproduction. 35, 7, p. 1693-1701Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinguishing between hidden testes and anorchia: The role of endocrine evaluation in infancy and childhood
Jespersen, K., Ljubicic, M. L., Johannsen, T. H., Christiansen, P., Skakkebæk, Niels Erik & Juul, Anders, 2020, In: European Journal of Endocrinology. 183, 1, p. 107-117 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A history of cryptorchidism is associated with impaired testicular function in early adulthood: a cross-sectional study of 6376 men from the general population
Koch, T., Hansen, A. H., Priskorn, L., Petersen, Jørgen Holm, Carlsen, E., Main, Katharina Maria, Skakkebæk, Niels Erik & Jørgensen, N., 2020, In: Human Reproduction. 35, 8, p. 1765-1780 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of psychological stress measured in three different scales on testis function: A cross-sectional study of 1362 young men
Nordkap, L., Priskorn, L., Bräuner, E. V., Hansen, Åse Marie, Kirstine Bang, A., Holmboe, S. A., Winge, S. B., Egeberg Palme, D. L., Mørup, N., Skakkebæk, Niels Erik, Kold Jensen, T. & Jørgensen, N., 2020, In: Andrology. 8, 6, p. 1674-1686 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular cancer: New inroads into early diagnosis
Rajpert-De Meyts, E., Znaor, A. & Skakkebæk, Niels Erik, 2020, World Cancer Report: Cancer Research for Cancer Prevention. Wild, C. P., Weiderpass, E. & Stewart, B. W. (eds.). IARC Press, p. 430-438 (World Cancer Reports).Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research › peer-review
- Published
Bisphenol A Diglycidyl Ether (BADGE) and Bisphenol Analogs, but Not Bisphenol A (BPA), Activate the CatSper Ca2+ Channel in Human Sperm
Rehfeld, Anders Aagaard, Andersson, A. M. & Skakkebæk, Niels Erik, 2020, In: Frontiers in Endocrinology. 11, 11 p., 324.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca2+ Signals in Boar Sperm Cells
Rehfeld, Anders Aagaard, Mendoza, N., Ausejo, R. & Skakkebæk, Niels Erik, 2020, In: Frontiers in Physiology. 11, p. 785Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular cancer incidence predictions in Europe 2010–2035: A rising burden despite population ageing
Znaor, A., Skakkebæk, Niels Erik, Rajpert‐de Meyts, E., Laversanne, M., Kuliš, T., Gurney, J., Sarfati, D., Mcglynn, K. A. & Bray, F., 2020, In: International Journal of Cancer. 147, 3, p. 820-828Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Proposed Key Characteristics of Male Reproductive Toxicants as an Approach for Organizing and Evaluating Mechanistic Evidence in Human Health Hazard Assessments
Arzuaga, X., Smith, M. T., Gibbons, C. F., Skakkebæk, Niels Erik, Yost, E. E., Beverly, B. E. J., Hotchkiss, A. K., Hauser, R., Pagani, R. L., Schrader, S. M., Zeise, L. & Prins, G. S., 2019, In: Environmental Health Perspectives. 127, 6, p. 1-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
Assens, M., Frederiksen, H., Petersen, Jørgen Holm, Larsen, T., Skakkebæk, Niels Erik, Juul, Anders, Andersson, A. & Main, Katharina Maria, 2019, In: Environment International. 123, p. 318-324 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between in-utero exposure to stressful life events during pregnancy and male reproductive function in a cohort of 20-year-old offspring: The Raine Study
Bräuner, E. V., Hansen, Åse Marie, Doherty, D. A., Dickinson, J. E., Handelsman, D. J., Hickey, M., Skakkebæk, Niels Erik, Juul, A. & Hart, R., 8 Jul 2019, In: Human reproduction (Oxford, England). 34, 7, p. 1345-1355 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Why Do Normal Children Have Acromegalic Levels of IGF-I During Puberty?
Juul, Anders & Skakkebæk, Niels Erik, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2770-2776Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35319116
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
Research output: Contribution to journal › Journal article › Research › peer-review
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215
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Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
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213
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
Research output: Contribution to journal › Journal article › Research › peer-review
Published