Niels Erik Skakkebæk
Affiliate Professor
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Anogenital distance as a phenotypic signature through infancy
Priskorn, L., Petersen, Jørgen Holm, Jørgensen, N., Kyhl, H. B., Andersen, M. S., Main, Katharina Maria, Andersson, A., Skakkebæk, Niels Erik & Jensen, T. K., 2018, In: Pediatric Research. 83, 3, p. 573-579 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Familial resemblance in markers of testicular function in fathers and their young sons: a cross-sectional study
Priskorn, L., Joensen, Ulla Nordström, Petersen, Jørgen Holm, Jensen, T. K., Skakkebæk, Niels Erik & Jørgensen, N., 2021, In: Human reproduction (Oxford, England). 36, 3, p. 543-550 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adverse trends in male reproductive health and decreasing fertility rates
Priskorn, L., Holmboe, S., Jørgensen, N., Andersson, A., Almstrup, Kristian, Toppari, J. & Skakkebæk, Niels Erik, 2012, In: Animal Reproduction Science. 31, 2, p. 760-771 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is Sedentary Lifestyle Associated With Testicular Function? A Cross-Sectional Study of 1,210 Men
Priskorn, L., Jensen, T. K., Bang, A. K., Nordkap, L., Joensen, Ulla Nordström, Lassen, T. H., Olesen, I. A., Swan, S. H., Skakkebæk, Niels Erik & Jørgensen, N., 15 Aug 2016, In: American Journal of Epidemiology. 184, 4, p. 284-294 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High maternal age at first and subsequent child births in Denmark in the mid-1800s-Letter to the editor
Priskorn, L., Dahl, C. L., Pihl, A. S., Skakkebæk, Niels Erik & Juul, Anders, Oct 2019, In: European Journal of Obstetrics & Gynecology and Reproductive Biology. 241, p. 137-138 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Increasing trends in childlessness in recent birth cohorts - a registry-based study of the total Danish male population born from 1945 to 1980
Priskorn, L., Holmboe, S., Jacobsen, R., Jensen, T. K., Lassen, T. H. & Skakkebæk, Niels Erik, 2012, In: International Journal of Andrology. 35, 3, p. 449-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Semen quality of young men in Switzerland: a nationwide cross-sectional population-based study
Rahban, R., Priskorn, L., Senn, A., Stettler, E., Galli, F., Vargas, J., Van den Bergh, M., Fusconi, A., Garlantezec, R., Jensen, T. K., Multigner, L., Skakkebæk, Niels Erik, Germond, M., Jørgensen, N., Nef, S. & The NICER Working Group, T. N. W. G., 2019, In: Andrology. 7, 6, p. 818-826Research output: Contribution to journal › Journal article › Research › peer-review
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The antidepressant Sertraline inhibits CatSper Ca2+channels in human sperm
Rahban, R., Rehfeld, Anders Aagaard, Schiffer, C., Brenker, C., Egeberg Palme, D. L., Wang, T., Lorenz, J., Almstrup, Kristian, Skakkebæk, Niels Erik, Strünker, T. & Nef, S., 2021, In: Human Reproduction. 36, 10, p. 2638-2648Research output: Contribution to journal › Journal article › Research › peer-review
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Increasing international efforts to understand and conquer testicular germ cell cancer
Rajpert-De Meyts, E., Daugaard, G., Almstrup, Kristian, Jørgensen, A., Rørth, M., Jørgensen, N., von der Maase, H. & Skakkebæk, Niels Erik, Jan 2015, In: Andrology. 3, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation
Rajpert-De Meyts, E., Poll, S. N., Goukasian, I., Jeanneau, C., Herlihy, A. S., Bennett, Eric Paul, Skakkebæk, Niels Erik, Clausen, Henrik, Giwercman, A. & Mandel, Ulla, 2007, In: Virchows Archiv. 451, 4, p. 805-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Goodbye International Journal of Andrology, welcome Andrology!
Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2022, In: Andrology. 10, S2, p. 133-138Research output: Contribution to journal › Editorial › Research › peer-review
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Prolonged expression of the c-kit receptor in germ cells of intersex fetal testes
Rajpert-De Meyts, E., Jørgensen, N., Müller, J. & Skakkebæk, Niels Erik, 1 Feb 1996, In: Journal of Pathology. 178, 2, p. 166-9 4 p.Research output: Contribution to journal › Journal article › Research
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The testis in childhood between birth and puberty
Rajpert-De Meyts, E., Almstrup, H. K. & Skakkebæk, Niels Erik, 2012, Atlas on the Human Testis: Normal Morphology and Pathology. p. 69-75 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Goodbye International Journal of Andrology, welcome Andrology!
Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2012, In: International Journal of Andrology. 36, 6, p. 769-774 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathogenesis of testicular carcinoma in situ and germ cell cancer: still more questions than answers
Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e2-6Research output: Contribution to journal › Journal article › Research › peer-review
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Optimised detection of germ cell neoplasia in situ in contralateral biopsy reduces the risk of second testis cancer
Rajpert-De Meyts, E., Jørgensen, N., Petersen, Jørgen Holm, Almstrup, Kristian, Aksglaede, L., Lauritsen, J., Rørth, M., Daugaard, G. & Skakkebæk, Niels Erik, 2022, In: BJU International. 130, 5, p. 646-654 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proceedings of the 7th Copenhagen Workshop on Testicular Carcinoma in situ and Germ Cell Cancer, 13-15 October 2010
Rajpert-De Meyts, E., Grigor, K. M. & Skakkebæk, Niels Erik, 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e1Research output: Contribution to journal › Journal article › Research
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Testicular Dysgenesis Syndrom and Carcinoma In Situ Testis
Rajpert-De Meyts, E., Almstrup, H. K. & Skakkebæk, Niels Erik, 2012, Atlas on the Human Testis. Jezek, D. (ed.). p. 159-178 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Testicular cancer: New inroads into early diagnosis
Rajpert-De Meyts, E., Znaor, A. & Skakkebæk, Niels Erik, 2020, World Cancer Report: Cancer Research for Cancer Prevention. Wild, C. P., Weiderpass, E. & Stewart, B. W. (eds.). IARC Press, p. 430-438 (World Cancer Reports).Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research › peer-review
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Cryptorchidism, hypospadias, testicular tumours and testicular dysgenesis syndrome
Rajpert-De Meyts, E., Main, Katharina Maria, Toppari, J. & Skakkebæk, Niels Erik, 2010, Endocrinology.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Origin of testicular germ cell neoplasia: The role of sex chromosomes
Rajpert-De Meyts, E., Ottesen, A. M., Høi-Hansen, Christina Engel, Sonne, Si Brask, Leffers, H. & Skakkebæk, Niels Erik, 1 Jan 2007, The Y Chromosome and Male Germ Cell Biology in Health and Diseases. World Scientific Publishing Co., p. 289-308 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Histopathological Evaluation of Testicular Biopsy
Rajpert-de Meyts, E., Grigor, K. M. & Skakkebæk, Niels Erik, 2017, Endocrinology of the Testis and Male Reproduction. SimoniIlpo, M. & Huhtaniemi, I. (eds.). p. 1-20 (Endocrinology of the Testis and Male Reproduction).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects
Rasmussen, M. H., Hvidberg, A., Juul, Anders, Main, Katharina Maria, Gotfredsen, A., Skakkebæk, Niels Erik, Hilsted, J. & Skakkebae, N. E., 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 4, p. 1407-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of stimulation of 24-hour growth hormone release by hypocaloric diet in obesity
Rasmussen, M. H., Juul, Anders, Kjems, L. L., Skakkebæk, Niels Erik & Hilsted, J., 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 3, p. 796-801 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prenatal and adult exposures to smoking are associated with adverse effects on reproductive hormones, semen quality, final height and body mass index
Ravnborg, T. L., Jensen, T. K., Andersson, A., Toppari, J., Skakkebæk, Niels Erik & Jørgensen, N., 18 Feb 2011, In: Human Reproduction. 26, 5, p. 1000-1011 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism
Rehfeld, Anders Aagaard, Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, Anders, Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical UV Filters Mimic the Effect of Progesterone on Ca(2+) Signaling in Human Sperm Cells
Rehfeld, Anders Aagaard, Dissing, Steen & Skakkebæk, Niels Erik, Nov 2016, In: Endocrinology. 157, 11, p. 4297-4308 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bisphenol A Diglycidyl Ether (BADGE) and Bisphenol Analogs, but Not Bisphenol A (BPA), Activate the CatSper Ca2+ Channel in Human Sperm
Rehfeld, Anders Aagaard, Andersson, A. M. & Skakkebæk, Niels Erik, 2020, In: Frontiers in Endocrinology. 11, 11 p., 324.Research output: Contribution to journal › Journal article › Research › peer-review
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Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
Rehfeld, Anders Aagaard, Palme, D. L. E., Almstrup, Kristian, Juul, Anders & Skakkebæk, Niels Erik, 2019, In: Journal of Visualized Experiments. 145, p. e59212Research output: Contribution to journal › Journal article › Research › peer-review
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
Rehfeld, Anders Aagaard, Egeberg, D., Almstrup, Kristian, Petersen, Jørgen Holm, Dissing, Steen & Skakkebæk, Niels Erik, 2018, In: Endocrine Connections. 7, 1, p. 16-25Research output: Contribution to journal › Journal article › Research › peer-review
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Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
Rehfeld, A., Egeberg Palme, D. L., Almstrup, K., Juul, Anders & Skakkebæk, Niels Erik, 1 Mar 2019, In: Journal of visualized experiments : JoVE. 145, 9 p., e59212.Research output: Contribution to journal › Journal article › Research › peer-review
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Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca2+ Signals in Boar Sperm Cells
Rehfeld, Anders Aagaard, Mendoza, N., Ausejo, R. & Skakkebæk, Niels Erik, 2020, In: Frontiers in Physiology. 11, p. 785Research output: Contribution to journal › Journal article › Research › peer-review
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An update on semen quality among young Finnish men and comparison with Danish data
Rodprasert, W., Virtanen, H. E., Sadov, S., Perheentupa, A., Skakkebæk, Niels Erik, Jørgensen, N. & Toppari, J., 2019, In: Andrology. 7, 1, p. 15-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reproductive Markers of Testicular Function and Size During Puberty in Boys With and Without a History of Cryptorchidism
Rodprasert, W., Koskenniemi, J. J., Virtanen, H. E., Sadov, S., Perheentupa, A., Ollila, H., Albrethsen, J., Andersson, A., Juul, Anders, Skakkebæk, Niels Erik, Main, Katharina Maria & Toppari, J., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 12, p. 3353-3361 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sperm retrieval in adolescent males with Klinefelter syndrome: medical and ethical issues
Rogol, A. D. & Skakkebæk, Niels Erik, Apr 2016, In: Translational Pediatrics. 5, 2, p. 104-106Research output: Contribution to journal › Comment/debate › Research
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Sperm Concentration, Testicular Volume and Age Predict Risk of Carcinoma In Situ in Contralateral Testis of Men with Testicular Germ Cell Cancer
Rud, C. N., Daugaard, G., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Petersen, Jørgen Holm & Jørgensen, N., 2013, In: Journal of Urology. 190, 6, p. 2074-2080 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contralateral biopsy in the management of testicular cancer: what we have learned and what we need to improve
Rørth, M., Grigor, K. M., Jørgensen, N., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., Jan 2015, In: Andrology. 3, 1, p. 99-101 3 p.Research output: Contribution to journal › Editorial › Research
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Carcinoma in situ in the testis
Rørth, M., Rajpert-De Meyts, E., Andersson, L., Dieckmann, Peter, Fosså, S. D., Grigor, K. M., Hendry, W. F., Herr, H. W., Looijenga, L. H., Oosterhuis, J. W. & Skakkebæk, Niels Erik, 2000, In: Scandinavian Journal of Urology and Nephrology, Supplementum. 205, p. 166-86 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular Growth During Puberty in Boys With and Without a History of Congenital Cryptorchidism
Sadov, S., Koskenniemi, J. J., Virtanen, H. E., Perheentupa, A., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Main, Katharina Maria & Toppari, J., Jun 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 6, p. 2570–2577 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serum testosterone levels in three-month-old boys predict their semen quality as young adults
Scheutz Henriksen, L., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Jørgensen, N., Virtanen, H. E., Priskorn, Lærke, Juul, Anders, Toppari, J. & Main, Katharina Maria, 2022, In: The Journal of clinical endocrinology and metabolism. 107, 7, p. 1965–1975 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Direct action of endocrine disrupting chemicals on human sperm
Schiffer, C., Müller, A., Egeberg, D. L., Alvarez, L., Brenker, C., Rehfeld, Anders Aagaard, Frederiksen, H., Wäschle, B., Kaupp, U. B., Balbach, M., Wachten, D., Skakkebæk, Niels Erik, Almstrup, Kristian & Strünker, T., Jul 2014, In: E M B O Reports. 15, 7, p. 758-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular germ cell cancer incidence in an immigration perspective, Denmark, 1978 to 2003
Schmiedel, S., Schüz, J., Skakkebæk, Niels Erik & Johansen, C., 1 Apr 2010, In: Journal of Urology. 183, 4, p. 1378-82 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Schmoll, H., Jordan, K., Huddart, R., Pes, M. P. L., Horwich, A., Fizazi, K., Kataja, V., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, ESMO Guidelines Working Group, E. G. W. G. & von der Maase, H. R. R., 1 May 2010, In: Annals of Oncology. 21 Suppl 5, p. v140-6Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular non-seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Schmoll, H., Jordan, K., Huddart, R., Pes, M. P. L., Horwich, A., Fizazi, K., Kataja, V., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, ESMO Guidelines Working Group, E. G. W. G. & von der Maase, H. R. R., 1 May 2010, In: Annals of Oncology. 21 Suppl 5, p. v147-54Research output: Contribution to journal › Journal article › Research › peer-review
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Serum inhibin A and inhibin B in healthy prepubertal, pubertal, and adolescent girls and adult women: relation to age, stage of puberty, menstrual cycle, follicle-stimulating hormone, luteinizing hormone, and estradiol levels
Sehested, A., Juul, Anders, Andersson, A. M., Petersen, Jørgen Holm, Jensen, T. K., Müller, J. & Skakkebæk, Niels Erik, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1634-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gene expression profiles of mouse spermatogenesis during recovery from irradiation
Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H., Almstrup, K., Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H. & Almstrup, Kristian, 1 Jan 2009, In: Reproductive Biology and Endocrinology. 7, p. 130Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro bioassay investigations of the endocrine disrupting potential of steviol glycosides and their metabolite steviol, components of the natural sweetener Stevia
Shannon, M., Rehfeld, Anders Aagaard, Frizzell, C., Livingstone, C., McGonagle, C., Skakkebæk, Niels Erik, Wielogórska, E. & Connolly, L., 15 May 2016, In: Molecular and Cellular Endocrinology. 427, p. 65-72Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects
Sharpe, R. M. & Skakkebæk, Niels Erik, 2008, In: Fertility and Sterility. 89, 2 Suppl, p. e33-e38Research output: Contribution to journal › Journal article › Research › peer-review
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Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland
Shen, H., Main, K. M., Andersson, A. M., Damgaard, I. N., Virtanen, H. E., Toppari, J., Schramm, K. W. & Skakkebæk, Niels Erik, 2008, In: Human Reproduction. 23, 1, p. 201-210 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations
Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Jørgensen, N., Main, Katharina Maria, Leffers, H., Andersson, A., Juul, Anders, Jensen, T. K. & Toppari, J., 2007, In: International Journal of Andrology. 30, 4, p. 198-204; discussion 204-5Research output: Contribution to journal › Review › Research
ID: 35319116
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
215
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Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
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215
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
Research output: Contribution to journal › Journal article › Research › peer-review
Published