Transfer of maternal IgE can be a common cause of increased IgE levels in cord blood
Research output: Contribution to journal › Journal article › Research › peer-review
IgE in cord blood is thought to be a product of the fetus. A high level of total IgE is therefore used as a measure of atopic propensity in the newborn. We recently found strong evidence that allergen-specific IgE in cord blood was the result of transfer of maternal IgE to fetal blood or cord blood (maternofetal transfer) rather than fetal production. This also suggests that total IgE in cord blood might primarily be a maternal product.
Original language | English |
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Journal | Journal of Allergy and Clinical Immunology |
Volume | 126 |
Issue number | 3 |
Pages (from-to) | 657-63 |
Number of pages | 7 |
ISSN | 0091-6749 |
DOIs | |
Publication status | Published - 1 Sep 2010 |
ID: 21833967