Thomas Werge
Clinical Professor
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Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
Vares, M., Saetre, P., Deng, H., Cai, G., Liu, X., Hansen, Thomas Folkmann, Rasmussen, Henrik Berg, Werge, Thomas, Melle, I., Djurovic, S., Andreassen, O. A., Agartz, I., Hall, H., Terenius, L. & Jönsson, E. G., 5 Mar 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 2, p. 610-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
Vassos, E., Steinberg, S., Cichon, S., Breen, G., Sigurdsson, E., Andreassen, O. A., Djurovic, S., Morken, G., Grigoroiu-Serbanescu, M., Diaconu, C. C., Czerski, P. M., Hauser, J., Babadjanova, G., Abramova, L. I., Mühleisen, T. W., Nöthen, M. M., Rietschel, M., McGuffin, P., St Clair, D., Gustafsson, O. & 28 others, , 2012, In: Biological Psychiatry. 72, 8, p. 645-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A study of the genetic architecture of social responsiveness in families with parental schizophrenia or bipolar disorder and population-based controls
Veddum, L., Greve, A. N., Gregersen, M., Andreassen, A. K., Knudsen, C. B., Brandt, J. M., Krantz, M. F., Søndergaard, A., Burton, B. K., Jepsen, J. R. M., Hemager, N., Werge, Thomas, Thorup, Anne, Nordentoft, Merete, Mors, O. & Nudel, R., 2023, In: Psychiatry Research. 326, 115280.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis
Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I., Buxbaum, J., iPSYCH-Broad ASD Group, the IMAGEN consortium, Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Burke Quinlan, E., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M. L. & 31 others, , 2018, In: Translational Psychiatry. 8, 1, 204.Research output: Contribution to journal › Journal article › Research › peer-review
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Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language
iPSYCH-Broad-PGC ADHD Consortium, I. A. C., 2019, In: Translational Psychiatry. 9, 1, 12 p., 35.Research output: Contribution to journal › Journal article › Research › peer-review
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Neuropeptide Y genes and suicidal behaviour among schizophrenic patients
Wang, August Gabriel, Koefoed, P., Jacoby, A. S., Woldbye, David Paul Drucker, Rasmussen, Henrik Berg, Timm, S., Dam, H., Jakobsen, K. D., Nordentoft, Merete, Jürgens, Gesche, Sorensen, H. J., Garsdal, O., Hvid, M. & Werge, Thomas, Jun 2013, In: Psychiatric Genetics. 23, 3, p. 139-40 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Suicidal Behavior and the Serotonin Transporter Gene Polymorphism (5-HTTLPR) with Novel Subtypes, in Danish Schizophrenic Patients
Wang, August Gabriel, Rasmussen, Henrik Berg, Sørensen, H. J., Hvid, M., Breddam, C. H., Hansen, B., Bille, V. H., Garsdal, O., Jacoby, A., Søbye, K., Dam, O. H., Krogsbøl, H., Timm, S. & Werge, Thomas, 2009, In: Open Psychiatry Journal.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
Wang, Y., Nudel, R., Benros, Michael Eriksen, Skogstrand, K., Fishilevich, S., Lancet, D., Sun, J., Hougaard, D. M., Andreassen, O. A., Mortensen, P. B., Buil, A., Hansen, Thomas Folkmann, Thompson, W. K., Werge, Thomas & iPSYCH-BROAD, I., 2020, In: PLOS Genetics. 16, 11, e1009163.Research output: Contribution to journal › Journal article › Research › peer-review
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Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS
Wang, Y., Thompson, W. K., Schork, A. J., Holland, D., Chen, C-H., Bettella, F., Desikan, R. S., Li, W., Witoelar, A., Zuber, V., Devor, A., Nöthen, M. M., Rietschel, M., Chen, Q., Werge, T., Cichon, S., Weinberger, D. R., Djurovic, S., O'Donovan, M. C., Visscher, P. M. & 2 others, , 2016, In: P L o S Genetics. 12, 1, 22 p., e1005803.Research output: Contribution to journal › Journal article › Research › peer-review
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Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations
Wang, Y., Karstoft, Karen-Inge, Nievergelt, C. M., Maihofer, A. X., Stein, M. B., Ursano, R. J., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Andreassen, O. A., Werge, Thomas, Thompson, W. K. & Andersen, S. B., 2019, In: Journal of Affective Disorders. 252, p. 350-357 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic correlates of phenotypic heterogeneity in autism
Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., Caceres, A. S. J., Hayward, H., Crawley, D., Faulkner, J., Sabet, J., Ellis, C., Oakley, B., Loth, E., Charman, T., Murphy, D., Holt, R. & 33 others, , 2022, In: Nature Genetics. 54, 9, p. 1293-1304 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Anorexia Nervosa Genetics Initiative, A. N. G. I., Aug 2019, In: Nature Genetics. 51, 8, p. 1207-1214Research output: Contribution to journal › Letter › Research › peer-review
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Common Genetic Variation and Age of Onset of Anorexia Nervosa
Watson, H. J., Thornton, L. M., Yilmaz, Z., Baker, J. H., Coleman, J. R. I., Adan, R. A. H., Alfredsson, L., Andreassen, O. A., Ask, H., Berrettini, W. H., Boehnke, M., Boehm, I., Boni, C., Buehren, K., Bulant, J., Burghardt, R., Chang, X., Cichon, S., Cone, R. D., Courtet, P. & 157 others, , 2022, In: Biological Psychiatry Global Open Science. 2, 4, p. 368-378 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p
Weiner, D. J., Ling, E., Erdin, S., Tai, D. J. C., Yadav, R., Grove, J., Fu, J. M., Nadig, A., Carey, C., Baya, N., Bybjerg-Grauholm, J., Mortensen, P. B., Werge, T., Demontis, D., Mors, O., Nordentoft, M., Als, T. D., Baekvad-Hansen, M., Rosengren, A., Havdahl, A. & 33 others, , 2022, In: Nature Genetics. 54, p. 1630-1639Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
Weiner, D. J., Wigdor, E. M., Ripke, S., Walters, R. K., Kosmicki, J. A., Grove, J., Samocha, K. E., Goldstein, J. I., Okbay, A., Bybjerg-Grauholm, J., Werge, T., Hougaard, D. M., Taylor, J., Skuse, D., Devlin, B., Anney, R., Sanders, S. J., Bishop, S., Mortensen, P. B., Børglum, A. D. & 32 others, , Jul 2017, In: Nature Genetics. 49, 7, p. 978-985 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Det genetiske grundlag for psykiske lidelser
Werge, Thomas & Fink-Jensen, Anders, 22 Mar 2010, In: Ugeskrift for Laeger. 172, 12, p. 962 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Response to Boot et al. Letter
Werge, Thomas, Ingason, A., Kirov, G., Rujescu, D. & Sigurdsson, E., 2012, In: American Journal of Psychiatry. 169, 1, p. 97 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic liability to ADHD and substance use disorders in individuals with ADHD
Wimberley, T., Agerbo, E., Horsdal, H. T., Ottosen, C., Brikell, I., Als, T. D., Demontis, D., Børglum, A. D., Nordentoft, Merete, Mors, O., Werge, Thomas, Hougaard, D., Bybjerg-Grauholm, J., Hansen, M. B., Mortensen, P. B., Thapar, A., Riglin, L., Langley, K. & Dalsgaard, S., 2020, In: Addiction. 115, 7, p. 1368-1377Research output: Contribution to journal › Journal article › Research › peer-review
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Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
Wirgenes, K. V., Djurovic, S., Agartz, I., Jonsson, E. G., Werge, Thomas, Melle, I., Andreassen, O. A., Wirgenes, K. V., Djurovic, S., Agartz, I., Jonsson, E. G., Werge, Thomas, Melle, I. & Andreassen, O. A., 2009, In: Neuropsychobiology. 60, 1, p. 31-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, T. M. D. D. W. G. O. T. P. G. C., 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A saturated map of common genetic variants associated with human height
Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, , 2022, In: Nature. 610, p. 704–712Research output: Contribution to journal › Journal article › Research › peer-review
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Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes
de Jong, S., van Eijk, K. R., Zeegers, D. W. L. H., Strengman, E., Janson, E., Veldink, J. H., van den Berg, L. H., Cahn, W., Kahn, R. S., Boks, M. P. M., Ophoff, R. A., PGC Schizophrenia (GWAS) Consortium, P. S. (. C., Werge, Thomas, Hansen, T., Ingason, A., Olsen, L. & Thygesen, J. H., 2012, In: European Journal of Human Genetics. 20, 9, p. 1004-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Schizophrenia genetic variants are not associated with intelligence
van Scheltinga, A. F. T., Bakker, S. C., van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Cahn, W., Ripke, S., Ophoff, R. A., Kahn, R. S., Psychiatric Genome-Wide Association Study (GWAS) Consortium, P. G. A. S. (. C., Werge, Thomas, Hansen, T. & Ingason, A., 2013, In: Psychological Medicine. p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia
van Schijndel, J. E., van Loo, K. M. J., van Zweeden, M., Djurovic, S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kallunki, P., Pedersen, J. T. & Martens, G. J. M., 2009, In: Journal of Psychiatric Research. 43, 15, p. 1195-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic risk score, psychosocial environment and the risk of attention-deficit/hyperactivity disorder
Østergaard, S. D., Trabjerg, B. B., Als, T. D., Climent, C. A., Privé, F., Vilhjálmsson, B. J., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Demontis, D., Mortensen, P. B., Børglum, A. D., Mors, O. & Agerbo, E., 2020, In: Translational Psychiatry. 10, 1, 335.Research output: Contribution to journal › Journal article › Research › peer-review
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Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk
International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu, I. M. S. G. C. E. A. C. C. E., Sellebjerg, Finn Thorup, Ullum, H. & Werge, Thomas, 29 Nov 2018, In: Cell. 175, 6, p. 1679-1687.e7Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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