Thomas Werge

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A. & 31 others, Van Der Auwera, S., Wray, N. R., Boomsma, D. I., Penninx, B. W. J. H., CHARGE InflammationWorking Group and the Major Depressive DisorderWorking Group of the Psychiatric Genomics Consortium, C. I. G. A. T. M. D. D. G. O. T. P. G. C., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bakvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschon, H. N., Bybjerg-Grauholm, J., Cai, N., Hansen, C. S., Hansen, T. F., Krogh, J., Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete & Werge, Thomas, Dec 2017, In: JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response

Larsen, K. M., Pellegrino, G., Birknow, M. R., Kjær, T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Mørup, M. & Siebner, Hartwig Roman, 2018, In: Schizophrenia Bulletin. 44, 2, p. 388–397

Research output: Contribution to journal › Journal article › Research › peer-review

AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

Nagy, S., Maurer, G. W., Hentze, J. L., Rose, M., Werge, Thomas & Rewitz, Kim, 2018, In: PLOS Genetics. 14, 12, e1007623.

Research output: Contribution to journal › Journal article › Research › peer-review

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties

St Pourcain, B., Robinson, E. B., Anttila, V., Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., Zammit, S., Fisher, S. E., Neale, B. M., Anney, R. J. L., Ripke, S., Hollegaard, M. V., Werge, T., iPSYCH-SSI-Broad Autism Group, Ronald, A., Grove, J., Hougaard, D. M. & 4 others, Børglum, A. D., Mortensen, P. B., Daly, M. J. & Davey Smith, G., 2018, In: Molecular Psychiatry. 23, 2, p. 263-270

Research output: Contribution to journal › Journal article › Research › peer-review

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Haan, L. D., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, Thomas Folkmann, Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Juliá, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'callaghan, E., O'dushlaine, C., O'neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Os, J. V., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, Thomas, Daly, M. J., Sullivan, P. F. & O'donovan, M. C., 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.

Research output: Contribution to journal › Journal article › Research › peer-review

Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Siebner, Hartwig Roman & Garrido, M. I., 2018, In: Schizophrenia Research. 197, p. 328-336

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of shared heritability in common disorders of the brain

Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 557 others, Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Leverenz, J. B., Levey, A. I., Lieberman, A. P., Pankratz, V. S., Poon, W. W., Quinn, J. F., Saykin, A. J., Schneider, L. S., Smith, A. G., Sonnen, J. A., Stern, R. A., Van Deerlin, V. M., Van Eldik, L. J., Harold, D., Russo, G., Rubinsztein, D. C., Bayer, A., Tsolaki, M., Proitsi, P., Fox, N. C., Hampel, H., Owen, M. J., Mead, S., Passmore, P., Morgan, K., Nöthen, M. M., Schott, J. M., Rossor, M., Lupton, M. K., Hoffmann, P., Kornhuber, J., Lawlor, B., Mcquillin, A., Al-Chalabi, A., Bis, J. C., Ruiz, A., Boada, M., Seshadri, S., Beiser, A., Rice, K., Van Der Lee, S. J., De Jager, P. L., Geschwind, D. H., Riemenschneider, M., Riedel-Heller, S., Rotter, J. I., Ransmayr, G., Hyman, B. T., Cruchaga, C., Alegret, M., Winsvold, B., Palta, P., Farh, K., Cuenca-Leon, E., Furlotte, N., Kurth, T., Ligthart, L., Terwindt, G. M., Freilinger, T., Ran, C., Gordon, S. D., Borck, G., Adams, H. H. H., Lehtimäki, T., Wedenoja, J., Buring, J. E., Schürks, M., Hrafnsdottir, M., Hottenga, J., Penninx, B., Artto, V., Kaunisto, M., Vepsäläinen, S., Martin, N. G., Montgomery, G. W., Kurki, M. I., Hämäläinen, E., Huang, H., Huang, J., Sandor, C., Webber, C., Muller-Myhsok, B., Schreiber, S., Salomaa, V., Loehrer, E., Göbel, H., Macaya, A., Pozo-Rosich, P., Hansen, T., Werge, Thomas, Kaprio, J., Metspalu, A., Kubisch, C., Ferrari, M. D., Belin, A. C., Van Den Maagdenberg, A. M. J. M., Zwart, J., Boomsma, D., Eriksson, N., Olesen, Jes, Chasman, D. I., Nyholt, D. R., Anney, R., Avbersek, A., Baum, L., Berkovic, S., Bradfield, J., Buono, R., Catarino, C. B., Cossette, P., De Jonghe, P., Depondt, C., Dlugos, D., Ferraro, T. N., French, J., Hjalgrim, H., Jamnadas-khoda, J., Kälviäinen, R., Kunz, W. S., Lerche, H., Leu, C., Lindhout, D., Lo, W., Lowenstein, D., Mccormack, M., Møller, R. S., Molloy, A., Ng, P., Oliver, K., Privitera, M., Radtke, R., Ruppert, A., Sander, T., Schachter, S., Schankin, C., Scheffer, I., Schoch, S., Sisodiya, S. M., Smith, P., Sperling, M., Striano, P., Surges, R., Thomas, G. N., Visscher, F., Whelan, C. D., Zara, F., Heinzen, E. L., Marson, A., Becker, F., Stroink, H., Zimprich, F., Gasser, T., Gibbs, R., Heutink, P., Martinez, M., Morris, H. R., Sharma, M., Ryten, M., Mok, K. Y., Pulit, S., Bevan, S., Holliday, E., Attia, J., Battey, T., Boncoraglio, G., Thijs, V., Chen, W., Mitchell, B., Rothwell, P., Sharma, P., Sudlow, C., Vicente, A., Markus, H., Kourkoulis, C., Pera, J., Raffeld, M., Silliman, S., Boraska Perica, V., Thornton, L. M., Huckins, L. M., William Rayner, N., Lewis, C. M., Gratacos, M., Rybakowski, F., Keski-Rahkonen, A., Raevuori, A., Hudson, J. I., Reichborn-Kjennerud, T., Monteleone, P., Karwautz, A., Mannik, K., Baker, J. H., O’toole, J. K., Trace, S. E., Davis, O. S. P., Helder, S. G., Ehrlich, S., Herpertz-dahlmann, B., Danner, U. N., Van Elburg, A. A., Clementi, M., Forzan, M., Docampo, E., Lissowska, J., Hauser, J., Tortorella, A., Maj, M., Gonidakis, F., Tziouvas, K., Papezova, H., Yilmaz, Z., Wagner, G., Cohen-woods, S., Herms, S., Julià, A., Rabionet, R., Dick, D. M., Ripatti, S., Andreassen, O. A., Espeseth, T., Lundervold, A. J., Steen, V. M., Pinto, D., Scherer, S. W., Aschauer, H., Schosser, A., Alfredsson, L., Padyukov, L., Halmi, K. A., Mitchell, J., Strober, M., Bergen, A. W., Kaye, W., Szatkiewicz, J. P., Cormand, B., Ramos-quiroga, J. A., Sánchez-mora, C., Ribasés, M., Casas, M., Hervas, A., Arranz, M. J., Haavik, J., Zayats, T., Johansson, S., Williams, N., Elia, J., Dempfle, A., Rothenberger, A., Kuntsi, J., Oades, R. D., Banaschewski, T., Franke, B., Buitelaar, J. K., Arias Vasquez, A., Doyle, A. E., Reif, A., Lesch, K., Freitag, C., Rivero, O., Palmason, H., Romanos, M., Langley, K., Rietschel, M., Witt, S. H., Dalsgaard, S., Børglum, A. D., Waldman, I., Wilmot, B., Molly, N., Bau, C. H. D., Crosbie, J., Schachar, R., Loo, S. K., Mcgough, J. J., Grevet, E. H., Medland, S. E., Robinson, E., Weiss, L. A., Bacchelli, E., Bailey, A., Bal, V., Battaglia, A., Betancur, C., Bolton, P., Cantor, R., Celestino-soper, P., Dawson, G., De Rubeis, S., Duque, F., Green, A., Klauck, S. M., Leboyer, M., Levitt, P., Maestrini, E., Mane, S., De-luca, D. M., Parr, J., Regan, R., Reichenberg, A., Sandin, S., Vorstman, J., Wassink, T., Wijsman, E., Cook, E., Santangelo, S., Delorme, R., Rogé, B., Magalhaes, T., Arking, D., Schulze, T. G., Thompson, R. C., Strohmaier, J., Matthews, K., Melle, I., Morris, D., Blackwood, D., Mcintosh, A., Bergen, S. E., Schalling, M., Jamain, S., Maaser, A., Fischer, S. B., Reinbold, C. S., Fullerton, J. M., Grigoroiu-serbanescu, M., Guzman-parra, J., Mayoral, F., Schofield, P. R., Cichon, S., Mühleisen, T. W., Degenhardt, F., Schumacher, J., Bauer, M., Mitchell, P. B., Gershon, E. S., Rice, J., Potash, J. B., Zandi, P. P., Craddock, N., Ferrier, I. N., Alda, M., Rouleau, G. A., Turecki, G., Ophoff, R., Pato, C., Anjorin, A., Stahl, E., Leber, M., Czerski, P. M., Edenberg, H. J., Cruceanu, C., Jones, I. R., Posthuma, D., Andlauer, T. F. M., Forstner, A. J., Streit, F., Baune, B. T., Air, T., Sinnamon, G., Wray, N. R., Macintyre, D. J., Porteous, D., Homuth, G., Rivera, M., Grove, J., Middeldorp, C. M., Hickie, I., Pergadia, M., Mehta, D., Smit, J. H., Jansen, R., De Geus, E., Dunn, E., Li, Q. S., Nauck, M., Schoevers, R. A., Beekman, A. T., Knowles, J. A., Viktorin, A., Arnold, P., Barr, C. L., Bedoya-berrio, G., Bienvenu, O. J., Brentani, H., Burton, C., Camarena, B., Cappi, C., Cath, D., Cavallini, M., Cusi, D., Darrow, S., Denys, D., Derks, E. M., Dietrich, A., Fernandez, T., Figee, M., Freimer, N., Gerber, G., Grados, M., Greenberg, E., Hanna, G. L., Hartmann, A., Hirschtritt, M. E., Hoekstra, P. J., Huang, A., Huyser, C., Illmann, C., Jenike, M., Kuperman, S., Leventhal, B., Lochner, C., Lyon, G. J., Macciardi, F., Madruga-garrido, M., Malaty, I. A., Maras, A., Mcgrath, L., Miguel, E. C., Mir, P., Nestadt, G., Nicolini, H., Okun, M. S., Pakstis, A., Paschou, P., Piacentini, J., Pittenger, C., Plessen, K., Ramensky, V., Ramos, E. M., Reus, V., Richter, M. A., Riddle, M. A., Robertson, M. M., Roessner, V., Rosário, M., Samuels, J. F., Sandor, P., Stein, D. J., Tsetsos, F., Van Nieuwerburgh, F., Weatherall, S., Wendland, J. R., Wolanczyk, T., Worbe, Y., Zai, G., Goes, F. S., Mclaughlin, N., Nestadt, P. S., Grabe, H., Depienne, C., Konkashbaev, A., Lanzagorta, N., Valencia-duarte, A., Bramon, E., Buccola, N., Cahn, W., Cairns, M., Chong, S. A., Cohen, D., Crespo-facorro, B., Crowley, J., Davidson, M., Delisi, L., Dinan, T., Donohoe, G., Drapeau, E., Duan, J., Haan, L., Hougaard, D., Karachanak-yankova, S., Khrunin, A., Klovins, J., Kučinskas, V., Lee Chee Keong, J., Limborska, S., Loughland, C., Lönnqvist, J., Maher, B., Mattheisen, M., Mcdonald, C., Murphy, K. C., Murray, R., Nenadic, I., Van Os, J., Pantelis, C., Pato, M., Petryshen, T., Quested, D., Roussos, P., Sanders, A. R., Schall, U., Schwab, S. G., Sim, K., So, H., Stögmann, E., Subramaniam, M., Toncheva, D., Waddington, J., Walters, J., Weiser, M., Cheng, W., Cloninger, R., Curtis, D., Gejman, P. V., Henskens, F., Mattingsdal, M., Oh, S., Scott, R., Webb, B., Breen, G., Churchhouse, C., Bulik, C. M., Daly, M., Dichgans, M., Faraone, S. V., Guerreiro, R., Holmans, P., Kendler, K. S., Koeleman, B., Mathews, C. A., Price, A., Scharf, J., Sklar, P., Williams, J., Wood, N. W., Cotsapas, C., Palotie, A., Smoller, J. W., Sullivan, P., Rosand, J., Corvin, A. & Neale, B. M., 2018, In: Science. 360, 6395, 40 p., eaap8757.

Research output: Contribution to journal › Journal article › Research › peer-review

Ancient genomes from Iceland reveal the making of a human population

Ebenesersdóttir, S. S., Sandoval Velasco, M., Gunnarsdóttir, E. D., Jagadeesan, A., Guðmundsdóttir, V. B., Thordardóttir, E. L., Einarsdóttir, M. S., Moore, K. H. S., Sigurðsson, Á., Magnusdóttir, D. N., Jonsson, H., Snorradóttir, S., Hovig, E., Møller, P., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T., Cavalleri, G. L. & 10 others, Gilbert, E., Lalueza-Fox, C., Walser, J. ,. I., Kristjánsdóttir, S., Gopalakrishnan, Shyam, Árnadóttir, L., Magnússon, Ó. Þ., Gilbert, M Thomas P, Stefánsson, K. & Helgason, A., 2018, In: Science. 360, 6392, p. 1028-1032 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

LaBianca, S., Pagsberg, Anne Katrine, Jakobsen, K. D., Demur, A. B., Bartalan, M., LaBianca, J. & Werge, Thomas, 2018, In: Journal of Autism and Developmental Disorders. 48, 10, p. 3629-3636 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., Carrera, N., Legge, S. E., Bishop, S., Cameron, D., Hamshere, M. L., Han, J., Hubbard, L., Lynham, A., Mantripragada, K., Rees, E., MacCabe, J. H., McCarroll, S. A., Baune, B. T., Breen, G., Byrne, E. M. & 51 others, Dannlowski, U., Eley, T. C., Hayward, C., Martin, N. G., McIntosh, A. M., Plomin, R., Porteous, D. J., Wray, N. R., Caballero, A., Geschwind, D. H., Huckins, L. M., Ruderfer, D. M., Santiago, E., Sklar, P., Stahl, E. A., Won, H., Agerbo, E., Als, T. D., Andreassen, O. A., Bækvad-Hansen, M., Mortensen, P. B., Pedersen, C. B., Børglum, A. D., Bybjerg-Grauholm, J., Djurovic, S., Durmishi, N., Pedersen, M. G., Golimbet, V., Grove, J., Hougaard, D. M., Mattheisen, M., Molden, E., Mors, O., Nordentoft, Merete, Pejovic-Milovancevic, M., Sigurdsson, E., Silagadze, T., Hansen, C. S., Stefansson, K., Stefansson, H., Steinberg, S., Tosato, S., Werge, Thomas, GERAD1 Consortium:, G. C., CRESTAR Consortium, C. C., Collier, D. A., Rujescu, D., Kirov, G., Owen, M. J., O'Donovan, M. C. & Walters, J. T. R., 2018, In: Nature Genetics. 50, p. 381-389

Research output: Contribution to journal › Journal article › Research › peer-review

Comorbidity of migraine with ADHD in adults

Hansen, Thomas Folkmann, Hoeffding, L. K., Kogelman, L., Haspang, T. M., Ullum, H., Sørensen, E., Erikstrup, C., Pedersen, O. B., Nielsen, K. R., Hjalgrim, H., Paarup, H. M., Werge, Thomas & Burgdorf, K., 2018, In: BMC Neurology. 18, 1, p. 1-9 147.

Research output: Contribution to journal › Journal article › Research › peer-review

Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder

Hughes, T., Sønderby, I. E., Polushina, T., Hansson, L., Holmgren, A., Athanasiu, L., Melbø-Jørgensen, C., Hassani, S., Hoeffding, L. K., Herms, S., Bergen, S. E., Karlsson, R., Song, J., Rietschel, M., Nöthen, M. M., Forstner, A. J., Hoffmann, P., Hultman, C. M., Landén, M., Cichon, S. & 4 others, Werge, Thomas, Andreassen, O. A., Le Hellard, S. & Djurovic, S., 2018, In: Translational Psychiatry. 8, 1, p. 1-12 210.

Research output: Contribution to journal › Journal article › Research › peer-review

GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS. O4.6.

Benros, Michael Eriksen, Nudel, R., Wang, Y., Appadurai, V., Schork, A., Agerbo, E., Werge, Thomas, Nordentoft, Merete, Mortensen, P., Buil, A. & Thompson, W., 2018, In: Schizophrenia Bulletin. 44, Suppl. 1, p. S85 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis

Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I., Buxbaum, J., iPSYCH-Broad ASD Group, the IMAGEN consortium, Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Burke Quinlan, E., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M. L. & 31 others, Artiges, E., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Hohmann, S., Fröhner, J. H., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Reichenberg, A., Børglum, A. D., Grove, J., Mattheisen, M., Werge, Thomas, Mortensen, P. B., Pedersen, M. G., Pedersen, C. B., Mors, O., Nordentoft, Merete, Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., Daly, M. J., Neale, B. M., Robinson, E. B., Cerrato, F., Dumont, A. & Goldstein, J., 2018, In: Translational Psychiatry. 8, 1, 204.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic risk scores and family history as predictors of schizophrenia in Nordic registers

Lu, Y., Pouget, J. G., Andreassen, O. A., Djurovic, S., Esko, T., Hultman, C. M., Metspalu, A., Milani, L., Werge, Thomas & Sullivan, P. F., 2018, In: Psychological Medicine. 48, 7, p. 1201-1208 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, T. M. D. D. W. G. O. T. P. G. C., 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C., Thomson, P. A., Porteous, D., Campbell, A., Smith, B. H., Black, C., Padmanabhan, S., McIntosh, A. M., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M. & 32 others, Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Hansen, C. S., Hansen, Thomas Folkmann, Krogh, J., Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete & Werge, Thomas, 2018, In: PLOS ONE. 13, 12, p. 1-29 e0209160.

Research output: Contribution to journal › Journal article › Research › peer-review

Molecular genetic overlap between migraine and major depressive disorder

Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, Pers, Tune H, Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas & Olesen, Jes, 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study

Olsen, L., Sparsø, T., Weinsheimer, S. M., Dos Santos, M. B. Q., Mazin, W., Rosengren, A., Sanchez, X. C., Hoeffding, L. K., Schmock, H., Baekvad-Hansen, M., Bybjerg-Grauholm, J., Daly, M. J., Neale, B. M., Pedersen, M. G., Agerbo, E., Mors, O., Børglum, A., Nordentoft, M., Hougaard, D. M., Mortensen, P. B. & 4 others, Geschwind, D. H., Pedersen, C., Thompson, W. K. & Werge, Thomas, 2018, In: The Lancet Psychiatry. 5, 7, p. 573-580 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

Ganna, A., Satterstrom, F. K., Zekavat, S. M., Das, I., Kurki, M. I., Churchhouse, C., Alfoldi, J., Martin, A. R., Havulinna, A. S., Byrnes, A., Thompson, W. K., Nielsen, P. R., Karczewski, K. J., Saarentaus, E., Rivas, M. A., Gupta, N., Pietiläinen, O., Emdin, C. A., Lescai, F., Bybjerg-Grauholm, J. & 28 others, Flannick, J., GoT2D/T2D-GENES Consortium, G. C., Mercader, J. M., Udler, M., SIGMA Consortium Helmsley IBD Exome Sequencing Project, S. C. H. I. E. S. P., FinMetSeq Consortium, F. C., iPSYCH-Broad Consortium, I. C., Laakso, M., Salomaa, V., Hultman, C., Ripatti, S., Hämäläinen, E., Moilanen, J. S., Körkkö, J., Kuismin, O., Nordentoft, Merete, Hougaard, D. M., Mors, O., Werge, Thomas, Mortensen, P. B., MacArthur, D., Daly, M. J., Sullivan, P. F., Locke, A. E., Palotie, A., Børglum, A. D., Kathiresan, S. & Neale, B. M., 2018, In: American Journal of Human Genetics. 102, 6, p. 1204-1211

Research output: Contribution to journal › Journal article › Research › peer-review

Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Fan, C. C., McGrath, J. J., Appadurai, V., Buil, A., Gandal, M. J., Schork, A. J., Mortensen, P. B., Agerbo, E., Geschwind, S. A., Geschwind, D., Werge, Thomas, Thompson, W. K. & Pedersen, C. B., 2018, In: Nature Communications. 9, 7 p., 5296.

Research output: Contribution to journal › Journal article › Research › peer-review

The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods

Thornton, L. M., Munn-Chernoff, M. A., Baker, J. H., Juréus, A., Parker, R., Henders, A. K., Larsen, J. T., Petersen, L., Watson, H. J., Yilmaz, Z., Kirk, K. M., Gordon, S., Leppä, V. M., Martin, F. C., Whiteman, D. C., Olsen, C. M., Werge, T. M., Pedersen, N. L., Kaye, W., Bergen, A. W. & 26 others, Halmi, K. A., Strober, M., Kaplan, A. S., Woodside, D. B., Mitchell, J., Johnson, C. L., Brandt, H., Crawford, S., Horwood, L. J., Boden, J. M., Pearson, J. F., Duncan, L. E., Grove, J., Mattheisen, M., Jordan, J., Kennedy, M. A., Birgegård, A., Lichtenstein, P., Norring, C., Wade, T. D., Montgomery, G. W., Martin, N. G., Landén, M., Mortensen, P. B., Sullivan, P. F. & Bulik, C. M., 2018, In: Contemporary Clinical Trials. 74, p. 61-69 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders

Pedersen, C. B., Bybjerg-Grauholm, J., Pedersen, M. G., Grove, J., Agerbo, E., Bækvad-Hansen, M., Poulsen, J. B., Hansen, C. S., McGrath, J. J., Als, T. D., Goldstein, J. I., Neale, B. M., Daly, M. J., Hougaard, D. M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Mortensen, P. B., 2018, In: Molecular Psychiatry. 23, p. 6-14 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

Haney, J. R., CommonMind Consortium, C. C., PsychENCODE Consortium, P. C. & iPSYCH-BROAD Working Group, I. W. G., 9 Feb 2018, In: Science. 359, 6376, p. 693-697 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register

Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 15 Mar 2018, In: Biological Psychiatry. 83, 6, p. 492-498

Research output: Contribution to journal › Journal article › Research › peer-review

Elevated polygenic burden for autism is associated with differential DNA methylation at birth

Hannon, E., Schendel, D., Ladd-Acosta, C., Grove, J., Hansen, C. S., Andrews, S. V., Hougaard, D. M., Bresnahan, M., Mors, O., Hollegaard, M. V., Bækvad-Hansen, M., Hornig, M., Mortensen, P. B., Børglum, A. D., Werge, T., Pedersen, M. G., Nordentoft, M., Buxbaum, J., Fallin, M. D., Bybjerg-Grauholm, J. & 2 others, Reichenberg, A. & Mill, J., 28 Mar 2018, In: Genome Medicine. 10, 13 p., 19.

Research output: Contribution to journal › Journal article › Research › peer-review

Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors

Didriksen, Maria, Allen, R. P., Burchell, B. J., Thørner, L. W., Rigas, A. S., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nielsen, K., Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., May 2018, In: Sleep Medicine. 45, p. 124-131 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journal › Journal article › Research › peer-review

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., Brikell, I., Ghirardi, L., Larsson, H., Lichtenstein, P., Eriksson, N., 23andMe Research Team, 2. R. T., Psychiatric Genomics Consortium: ADHD Subgroup, P. G. C. A. S., iPSYCH–Broad ADHD Workgroup, I. A. W., Werge, Thomas & Nordentoft, Merete, 15 Jun 2018, In: Biological Psychiatry. 83, 12, p. 1044-1053 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Socio-demographic characteristics of adults with self-reported ADHD symptoms in a Danishpopulation of 12,415 blood donors

Høffding, L. K. E., Nielsen, Maria Haahr, Didriksen, Maria, Schow, T., Werge, Thomas, Nielsen, K. R., Erikstrup, C., Pedersen, O. B., Hjalgrim, H., Jepsen, J. R. M., Hansen, T. F., Banasik, K., Ullum, H. & Burgdorf, K., 20 Aug 2018, In: Journal of Psychiatry and Behavioral Sciences. 3

Research output: Contribution to journal › Journal article › Research › peer-review

Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk

International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu, I. M. S. G. C. E. A. C. C. E., Sellebjerg, Finn Thorup, Ullum, H. & Werge, Thomas, 29 Nov 2018, In: Cell. 175, 6, p. 1679-1687.e7

Research output: Contribution to journal › Journal article › Research › peer-review

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease

Hagen, C. M., Gonçalves, V. F., Hedley, P. L., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., Kanters, Jørgen K., Nielsen, J., Mors, O., Demur, A. B., Als, T. D., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Kennedy, J., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 1 Dec 2018, In: PLoS ONE. 13, 12, 14 p., e0208828.

Research output: Contribution to journal › Journal article › Research › peer-review

Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes

Bybjerg-Grauholm, J., Hagen, C. M., Gonçalves, V. F., Bækvad-Hansen, M., Hansen, C. S., Hedley, P. L., Kanters, Jørgen K., Nielsen, J., Theisen, M., Mors, O., Kennedy, J., Als, T. D., Demur, A. B., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 13 Dec 2018, In: PLoS ONE. 13, 12, 26 p., e0208829.

Research output: Contribution to journal › Journal article › Research › peer-review

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

Nudel, R., Wang, Y., Appadurai, V., Schork, A. J., Buil, A., Agerbo, E., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, 2019, In: Translational Psychiatry. 9, 1, 10 p., 283.

Research output: Contribution to journal › Journal article › Research › peer-review

Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study

Choi, K. W., Chen, C. Y., Stein, M. B., Klimentidis, Y. C., Wang, M. J., Koenen, K. C., Smoller, J. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F. & 31 others, Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Hansen, T. F., Krogh, J., Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: JAMA Psychiatry. 76, 4, p. 399-408 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia

Horsdal, H. T., Agerbo, E., McGrath, J. J., Vilhjálmsson, B. J., Antonsen, S., Closter, A. M., Timmermann, A., Grove, J., Mok, P. L. H., Webb, R. T., Sabel, C. E., Hertel, O., Sigsgaard, T., Erikstrup, C., Hougaard, D. M., Werge, T., Nordentoft, M., Børglum, A. D., Mors, O., Mortensen, P. B. & 3 others, Brandt, J., Geels, C. & Pedersen, C. B., 2019, In: JAMA Network Open. 2, 11, 12 p., e1914401.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia with Risk for Depression in the Danish Population

Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Andreassen, O., Pedersen, C. B., Pedersen, M. G., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Agerbo, E., 2019, In: JAMA Psychiatry. 76, 5, p. 516-525 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Mcintosh, A. M., Whalley, H. C., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 216 others, Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S., Bækvad-hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. R. I., Colodro-conde, L., Couvy-duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-price, V., Hassan Kiadeh, F. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J., Hougaard, D. M., Ising, M., Jansen, R., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Li, Y., Lind, P. A., Macintyre, D. J., Mackinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., Mcgrath, P., Mcguffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. J. C., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., Mcintosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-myhsok, B., Nordentoft, Merete, Nöthen, M. M., O'donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, Thomas, Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hinds, D. A., Huber, K. E., Kleinman, A., Litterman, N. K., Mccreight, J. C., Mcintyre, M. H., Mountain, J. L., Noblin, E. S., Northover, C. A. M., Pitts, S. J., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Shringarpure, S., Tian, C., Tung, J. Y., Vacic, V. & Wilson, C. H., 2019, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants

Satterstrom, F. K., Walters, R. K., Singh, T., Wigdor, E. M., Lescai, F., Demontis, D., Kosmicki, J. A., Grove, J., Stevens, C., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Palmer, D. S., Maller, J. B., Nordentoft, M., Mors, O., Robinson, E. B., Hougaard, D. M., Werge, T. M., Bo Mortensen, P., Neale, B. M. & 3 others, Børglum, A. D., Daly, M. J. & iPSYCH-Broad Consortium, I. C., 2019, In: Nature Neuroscience. 22, 12, p. 1961-1965

Research output: Contribution to journal › Journal article › Research › peer-review

BIOLOGICAL PREDICTORS OF PSYCHIATRIC TRAJECTORIES IN A DANISH POPULATION COHORT OF INDIVIDUALS WITH SCHIZOPHRENIA

Krebs, M., Themudo, G. E., Benros, Michael Eriksen, Werge, Thomas & Thompson, W., 2019, In: European Neuropsychopharmacology. 29, S5, p. S260-S260 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Can Animal Models of Copy Number Variants That Predispose to Schizophrenia Elucidate Underlying Biology?

Forsingdal, A., Jørgensen, T. N., Olsen, L., Werge, Thomas, Didriksen, M. & Nielsen, J., 2019, In: Biological Psychiatry. 85, 1, p. 13-24 12 p.

Research output: Contribution to journal › Review › Research › peer-review

Clinical association to FKBP5 rs1360780 in patients with depression

Dam, H., Buch, J. O. D., Nielsen, A. B., Weikop, Pia, Werge, Thomas & Jørgensen, M. B., 2019, In: Psychiatric Genetics. 29, 6, p. 220-225 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language

iPSYCH-Broad-PGC ADHD Consortium, I. A. C., 2019, In: Translational Psychiatry. 9, 1, 12 p., 35.

Research output: Contribution to journal › Journal article › Research › peer-review

Exploring Comorbidity Within Mental Disorders among a Danish National Population

Plana-Ripoll, O., Pedersen, C. B., Holtz, Y., Benros, M. E., Dalsgaard, S., De Jonge, P., Fan, C. C., Degenhardt, L., Ganna, A., Greve, A. N., Gunn, J., Iburg, K. M., Kessing, L. V., Lee, B. K., Lim, C. C. W., Mors, O., Nordentoft, M., Prior, A., Roest, A. M., Saha, S. & 12 others, Schork, A., Scott, J. G., Scott, K. M., Stedman, T., Sørensen, H. J., Werge, Thomas, Whiteford, H. A., Laursen, T. M., Agerbo, E., Kessler, R. C., Mortensen, P. B. & McGrath, J. J., 2019, In: JAMA Psychiatry. 76, 3, p. 259-270

Research output: Contribution to journal › Journal article › Research › peer-review

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C. B. D. W. G. O. T. P. G. C. S. W. G. O. T. P. G. C., Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C. M., 2019, In: American Journal of Psychiatry. 176, 8, p. 651-660

Research output: Contribution to journal › Journal article › Research › peer-review

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardiñas, A. F., Rajagopal, V. M., Als, T. D., T. Nguyen, H., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Domenici, E., Gamazon, E. R., Purcell, S., CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, iPSYCH-GEMS Schizophrenia Working Group & 15 others, Johnson, J. S., Shah, H. R., Klein, L. L., Pers, T. H., Hansen, T., Olsen, L., Rasmussen, H. B., Werge, Thomas, Pedersen, C. B., Nordentoft, Merete, Bækvad-Hansen, M., Hansen, C. S., Daly, M. J., Sullivan, P. F. & O'Donovan, M. C., 2019, In: Nature Genetics. 51, p. 659-674

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic Variants Associated with Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study

Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., Bækved-Hansen, M., Sokolowska, E., Mortensen, P. B., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Breen, G., Børglum, A. D., Eley, T. C., Hovatta, I., Mattheisen, M. & Mors, O., 2019, In: JAMA Psychiatry. 76, 9, p. 924-932 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study implicates CHRNA2 in cannabis use disorder

Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., Gudbjartsson, D. F., Pallesen, J., Hjorthøj, C., Reginsson, G. W., Tyrfingsson, T., Runarsdottir, V., Qvist, P., Christensen, J. H., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Huckins, L. M., Stahl, E. A., Timmermann, A., Agerbo, E. & 10 others, Hougaard, D. M., Werge, Thomas, Mors, O., Mortensen, P. B., Nordentoft, Merete, Daly, M. J., Stefansson, H., Stefansson, K., Nyegaard, M. & Børglum, A. D., 2019, In: Nature Neuroscience. 22, 7, p. 1066-1074

Research output: Contribution to journal › Journal article › Research › peer-review

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Cell. 179, 7, p. 1469-1482 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genomisk medicin som forbrugervare

Folkersen, L. & Werge, Thomas, 2019, In: Ugeskrift for Laeger. 181, 5 p., V11180789.

Research output: Contribution to journal › Journal article › Research › peer-review

Human Disease Variation in the Light of Population Genomics

Prohaska, Ana, Racimo, Fernando, Schork, A. J., Sikora, Martin, Stern, A. J., Ilardo, M., Allentoft, Morten Erik, Folkersen, L., Buil, A., Moreno Mayar, J. Víctor, Korneliussen, Thorfinn Sand, Geschwind, D., Ingason, A., Werge, Thomas, Nielsen, Rasmus & Willerslev, Eske, 2019, In: Cell. 177, 1, p. 115-131 17 p.

Research output: Contribution to journal › Review › Research › peer-review

Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders

Nudel, R., Benros, Michael Eriksen, Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Nordentoft, Merete, Mors, O., Hougaard, D. M., Mortensen, P. B., Buil, A., Werge, Thomas, Rasmussen, Simon & Thompson, W. K., 2019, In: European Journal of Human Genetics. 27, p. 1445-1455

Research output: Contribution to journal › Journal article › Research › peer-review

Individuals with 22q11.2 deletion syndrome show intact prediction but reduced adaptation in responses to repeated sounds: Evidence from Bayesian mapping

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Olsen, L., Didriksen, M., Baaré, W. F. C., Werge, Thomas, Garrido, M. I. & Siebner, Hartwig Roman, 2019, In: NeuroImage: Clinical. 22, 101721.

Research output: Contribution to journal › Journal article › Research › peer-review

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Nature Communications. 10, 1, 18 p., 2548.

Research output: Contribution to journal › Journal article › Research › peer-review

Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions

Giovanoli, S., Werge, Thomas, Mortensen, P. B., Didriksen, M. & Meyer, U., 2019, In: Neuropsychopharmacology. 44, 4, p. 703-710 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C-Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M., Amstadter, A. B. & 159 others, Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegovic, E., Babić, D., Bækvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Børglum, A. D., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas- de- Almeida, J. M., Dale, A. M., Daly, M. J., Daskalakis, N. P., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Dzubur-Kulenovic, A., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gelaye, B., Geuze, E., Gillespie, C., Uka, A. G., Gordon, S. D., Guffanti, G., Hammamieh, R., Harnal, S., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljevic, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X., Junglen, A. G., Karstoft, Karen-Inge, Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C. E., Linnstaedt, S. D., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J., Marmar, C., Martin, A. R., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., McLeay, S., Mehta, D., Milberg, W. P., Miller, M. W., Morey, R. A., Morris, C. P., Mors, O., Mortensen, P. B., Neale, B. M., Nelson, E. C., Nordentoft, Merete, Norman, S. B., O’Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Ripke, S., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stevens, J. S., Sumner, J. A., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., van den Heuvel, L. L., Van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Werge, Thomas, Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Wolff, J. D., Yehuda, R., Young, R. M., Young, K. A., Zhao, H., Zoellner, L. A., Liberzon, I., Ressler, K. J., Haas, M. & Koenen, K. C., 2019, In: Nature Communications. 10, 1, 4558.

Research output: Contribution to journal › Journal article › Research › peer-review

Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders

Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, K., Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, D., Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, S., Pedersen, C. B., Fuller Torrey, E., Werge, T., Bo Mortensen, P. & 2 others, Yolken, R. & Ullum, H., 2019, In: Brain, Behavior, and Immunity. 79, p. 152-158

Research output: Contribution to journal › Journal article › Research › peer-review

Migraine polygenic risk score associates with efficacy of migraine-specific drugs

Kogelman, L. J. A., Esserlind, A-L., Christensen, A. F., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B., Erikstrup, C., Hjalgrim, H., Ullum, H., Olesen, J., Hansen, T. F., Gudbjartsson, D., Gastafsson, O., Stefansson, K., Stefansson, H., Porsteinsdottir, U., Andersen, S., Banasik, K., Brunak, S. & 73 others, Buil, A., Burgdorf, K., Gregor, J., Jennum, Poul, Nielsen, K. R., Nyegaard, M., Paarup, H. M., Pedersen, O. B., Sørensen, E., Werge, Thomas, Anttila, V., Artto, V., Belin, A. C., de Boer, I., Boomsma, D. I., Borte, S., Chasman, D. I., Cherkas, L., Cormand, B., Cuenca-Leon, E., Davey-Smith, G., Dichgans, M., van Duijn, C., Esko, T., Ferrari, M., Frants, R. R., Freilinger, T., Furlotte, N., Gormley, P., Griffiths, L., Hamalainen, E., Hiekkala, M., Ikram, M. A., Jarvelin, M., Kajanne, R., Kallela, M., Kaprio, J., Kaunisto, M., Kubisch, C., Kurki, M., Kurth, T., Launer, L., Lehtimaki, T., Lessel, D., Ligthart, L., Litterman, N., van den Maagdenberg, A., Macaya, A., Malik, R., Mangino, M., McMahon, G., Muller-Myhsok, B., Neale, B. M., Northover, C., Nyholt, D. R., Palotie, A., Palta, P., Pedersen, L., Pedersen, N., Posthuma, D., Pozo-Rosich, P., Pressman, A., Raitakari, O., Schurks, M., Sintas, C., Steinberg, S., Strachan, D., Terwindt, G., Vila-Pueyo, M., Wessman, M., Winsvold, B. S., Zhao, H. & Zwart, J., 2019, In: Neurology: Genetics. 5, 6, 12 p., e364.

Research output: Contribution to journal › Journal article › Research › peer-review

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A. & 32 others, Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Hopkins, L., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Pers, Tune H, Hansen, M., Hansen, Thomas Folkmann, Li, T., Olsen, L., Pantelis, C., Rasmussen, Henrik Berg, Werge, Thomas, Wellcome Trust Case Control Consortium 2, W. T. C. C. C. 2. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations

Wang, Y., Karstoft, Karen-Inge, Nievergelt, C. M., Maihofer, A. X., Stein, M. B., Ursano, R. J., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Andreassen, O. A., Werge, Thomas, Thompson, W. K. & Andersen, S. B., 2019, In: Journal of Affective Disorders. 252, p. 350-357 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders

Skogstrand, K., Hagen, C. M., Borbye-Lorenzen, N., Christiansen, M., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Werge, Thomas, Borglum, A., Mors, O., Nordentoft, M., Mortensen, P. B. & Hougaard, D. M., 2019, In: Translational Psychiatry. 9, 9 p., 252.

Research output: Contribution to journal › Journal article › Research › peer-review

Roadmap for a precision-medicine initiative in the Nordic region

Njølstad, P. R., Andreassen, O. A., Brunak, S., Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A., Mortensen, P. B., Palmgren, J. & 11 others, Palotie, A., Reed, W., Stefánsson, H., Stitziel, N. O., Sullivan, P. F., Thorsteinsdóttir, U., Vaudel, M., Vuorio, E., Werge, Thomas, Stoltenberg, C. & Stefánsson, K., 2019, In: Nature Genetics. 51, p. 924-930

Research output: Contribution to journal › Comment/debate › Research

Schizophrenia polygenic risk scores, urbanicity and treatment-resistant schizophrenia

Gasse, C., Wimberley, T., Wang, Y., Mors, O., Børglum, A., Als, T. D., Werge, Thomas, Nordentoft, Merete, Hougaard, D. M. & Horsdal, H. T., 2019, In: Schizophrenia Research. 212, p. 79-85 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

ADHD Working Group of the Psychiatric Genomics Consortium (PGC), A. W. G. O. T. P. G. C. (., Jan 2019, In: Nature Genetics. 51, 1, p. 63-75 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D., Bo Mortensen, P. & 4 others, Buil, A., Thompson, W. K., Geschwind, D. H. & Werge, Thomas, Mar 2019, In: Nature Neuroscience. 22, 3, p. 353-361

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, A. S. D. W. G. O. T. P. G. C., Mar 2019, In: Nature Genetics. 51, 3, p. 431-444

Research output: Contribution to journal › Journal article › Research › peer-review

Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight

iPSYCH-Broad ASD Group, I. A. G., 15 Apr 2019, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 374, 1770, 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, E. C., May 2019, In: Nature Genetics. 51, 5, p. 793-803

Research output: Contribution to journal › Journal article › Research › peer-review

DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors

Hansen, T. F., Banasik, K., Erikstrup, C., Pedersen, O. B., Westergaard, D., Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, P., Andersen, S., Nyegaard, M., Jemec, G. B. E., Olesen, J., Werge, T., Johansson, P. I., Sørensen, E. & 3 others, Brunak, Søren, Ullum, H. & Burgdorf, Kristoffer Sølvsten, 9 Jun 2019, In: BMJ Open. 9, 6, p. 1-7 7 p., e028401.

Research output: Contribution to journal › Journal article › Research › peer-review

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

GERAD1 Consortium:, G. C., Jul 2019, In: Nature Genetics. 51, 7, p. 1193 1 p.

Research output: Contribution to journal › Comment/debate › Research

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Anorexia Nervosa Genetics Initiative, A. N. G. I., Aug 2019, In: Nature Genetics. 51, 8, p. 1207-1214

Research output: Contribution to journal › Letter › Research › peer-review

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A., Rossi, R. M. & 54 others, Skogstrand, K., Peng, S., Thompson, W. K., Appadurai, V., Lawlor, D. A., Kalliala, I., Power, C., McCarthy, M. I., Boyd, H. A., Marazita, M. L., Hakonarson, H., Hayes, M. G., Scholtens, D. M., Rivadeneira, F., Jaddoe, V. W. V., Vinding, R. K., Bisgaard, H., Knight, B. A., Pahkala, K., Raitakari, O., Helgeland, Ø., Johansson, S., Njølstad, P. R., Fadista, J., Schork, A. J., Nudel, R., Miller, D. E., Chen, X., Weirauch, M. T., Mortensen, P. B., Børglum, A. D., Nordentoft, Merete, Mors, O., Hao, K., Ryckman, K. K., Hougaard, D. M., Kottyan, L. C., Pennell, C. E., Lyytikainen, L., Bønnelykke, Klaus, Vrijheid, M., Felix, J. F., Lowe, W. L., Grant, S. F. A., Hyppönen, E., Jacobsson, B., Jarvelin, M., Muglia, L. J., Murray, J. C., Freathy, R. M., Werge, Thomas, Melbye, M., Buil, A. & Feenstra, B., 2 Sep 2019, In: Nature Communications. 10, 1, 13 p., 3927.

Research output: Contribution to journal › Journal article › Research › peer-review

Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population

Nissen, J., Trabjerg, B., Pedersen, M. G., Banasik, K., Pedersen, O. B., Sørensen, E., Nielsen, K. R., Erikstrup, C., Petersen, M. S., Paarup, H. M., Bruun-Rasmussen, P., Westergaard, D., Hansen, T. F., Pedersen, C. B., Werge, T., Torrey, F., Hjalgrim, H., Mortensen, P. B., Yolken, R., Brunak, S. & 2 others, Ullum, H. & Burgdorf, K. S., Oct 2019, In: Psychoneuroendocrinology. 108, p. 150-154

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders

Bauer, A. E., Liu, X., Byrne, E. M., Sullivan, P. F., Wray, N. R., Agerbo, E., Nyegaard, M., Grove, J., Musliner, K. L., Ingstrup, K. G., Johannsen, B. M. W., Mægbæk, M. L., Wang, Y., Nordentoft, M., Mors, O., Børglum, A. D., Werge, T., Hougaard, D. M., Mortensen, P. B., Munk-Olsen, T. & 1 others, Meltzer-Brody, S., 11 Nov 2019, In: Translational Psychiatry. 9, 1, 13 p., 288.

Research output: Contribution to journal › Journal article › Research › peer-review

FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Agerbo, E., Gern, J. E., Lemanske, R. F., Ober, C., Pedersen, A. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Nature Communications. 11, 12 p., 6398.

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, The International Headache Genetics Consortium, T. I. H. G. C. & the 23andMe Research Team, T. 2. R. T., 2020, In: Nature Communications. 11, 1, 3368.

Research output: Contribution to journal › Journal article › Research › peer-review

A large-scale genome-wide association study meta-analysis of cannabis use disorder

Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., Sanchez-Roige, S., Paul, S. E., Wendt, F. R., Clarke, T. K., Lai, D., Reginsson, G. W., Zhou, H., He, J., Baranger, D. A. A., Gudbjartsson, D. F., Wedow, R., Adkins, D. E., Adkins, A. E., Alexander, J. & 31 others, Bacanu, S. A., Bigdeli, T. B., Boden, J., Brown, S. A., Bucholz, K. K., Bybjerg-Grauholm, J., Corley, R. P., Degenhardt, L., Dick, D. M., Domingue, B. W., Fox, L., Goate, A. M., Gordon, S. D., Hack, L. M., Hancock, D. B., Hartz, S. M., Hickie, I. B., Hougaard, D. M., Krauter, K., Lind, P. A., McClintick, J. N., McQueen, M. B., Meyers, J. L., Montgomery, G. W., Mors, O., Mortensen, P. B., Nordentoft, Merete, Pearson, J. F., Peterson, R. E., Werge, Thomas & Psychiatric Genomics Consortium Substance Use Disorders Workgroup, P. G. C. S. U. D. W., 2020, In: The Lancet Psychiatry. 7, 12, p. 1032-1045 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A major role for common genetic variation in anxiety disorders

Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O., Bo Mortensen, P. & 6 others, Nordentoft, Merete, Werge, Thomas, Nicodemus, K. K., Mattheisen, M., Breen, G. & Eley, T. C., 2020, In: Molecular Psychiatry. 25, p. 3292–3303

Research output: Contribution to journal › Journal article › Research › peer-review

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. K., Adams, M. J., Clarke, T. K., McIntosh, A. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M. & 31 others, Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Hansen, C. S., Hansen, T. F., Pedersen, C. B., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Nature Communications. 11, 1, 2301.

Research output: Contribution to journal › Journal article › Research › peer-review

Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression

Paksarian, D., Trabjerg, B. B., Merikangas, K. R., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Pedersen, C. B., Mortensen, P. B., Agerbo, E. & Horsdal, H. T., 2020, In: British Journal of Psychiatry. 217, 1, p. 390-396 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control

Maurer, G. W., Malita, Alina, Nagy, S., Koyama, Takashi, Werge, Thomas, Halberg, Kenneth Veland, Texada, Michael James & Rewitz, Kim, 2020, In: PLOS Genetics. 16, 4, 31 p., e1008727.

Research output: Contribution to journal › Journal article › Research › peer-review

Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia

Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M., McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, Merete, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, Thomas, Svenning, J. C. & Horsdal, H. T., 2020, In: Schizophrenia Bulletin. 46, 6, p. 1629-1637 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association between GLP-1 receptor gene polymorphisms with reward Learning, anhedonia, and depression diagnosis

Eser, H. Y., Appadurai, V., Eren, C. Y., Yazici, D., Chen, C. Y., Ongur, D., Pizzagalli, D. A., Werge, Thomas & Hall, M. H., 2020, In: Acta Neuropsychiatrica. 32, 4, p. 218-225

Research output: Contribution to journal › Journal article › Research › peer-review

Association between Mental Disorders and Subsequent Medical Conditions

Momen, N. C., Plana-Ripoll, O., Agerbo, E., Benros, M. E., Børglum, A. D., Christensen, M. K., Dalsgaard, S., Degenhardt, L., de Jonge, P., Debost, J-C. P. G., Fenger-Grøn, M., Gunn, J. M., Iburg, K. M., Kessing, L. V., Kessler, R. C., Laursen, T. M., Lim, C. C. W., Mors, O., Mortensen, P. B., Musliner, K. L. & 18 others, Nordentoft, Merete, Pedersen, C. B., Petersen, L. V., Ribe, A. R., Roest, A. M., Saha, S., Schork, A. J., Scott, K. M., Sievert, C., Sørensen, H. J., Stedman, T. J., Vestergaard, M., Vilhjalmsson, B., Werge, Thomas, Weye, N., Whiteford, H. A., Prior, A. & McGrath, J. J., 2020, In: The New England Journal of Medicine. 382, 18, p. 1721-1731 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cerebral small vessel disease genomics and its implications across the lifespan

Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S. P., Kumar, R. B., van den Akker, E. B., McWhirter, R. E., Trompet, S., Mishra, A. & 32 others, Saba, Y., Satizabal, C. L., Beaudet, G., Petit, L., Tsuchida, A., Zago, L., Schilling, S., Sigurdsson, S., Gottesman, R. F., Lewis, C. E., Aggarwal, N. T., Lopez, O. L., Smith, J. A., Valdés Hernández, M. C., van der Grond, J., Wright, M. J., Knol, M. J., Dörr, M., Thomson, R. J., Bordes, C., Le Grand, Q., Duperron, M. G., Smith, A. V., Niessen, W. J., Pers, Tune H, Ingason, A., Francke Christensen, A., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, International Network against Thrombosis (INVENT) Consortium, I. N. A. T. (. C. & International Headache Genomics Consortium (IHGC), I. H. G. C. (., 2020, In: Nature Communications. 11, 1, 18 p., 6285.

Research output: Contribution to journal › Journal article › Research › peer-review

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., de Geus, E. J. C. & 31 others, Grabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Magnusson, P. K., McGuffin, P., McIntosh, A. M., Milaneschi, Y., Mors, O., Mostafavi, S., Müller-Myhsok, B., Pedersen, N. L., Penninx, B. W. J. H., Potash, J. B., Preisig, M., Ripke, S., Shi, J., Bækvad-Hansen, M., Hansen, C. S., Hansen, Thomas Folkmann, Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Biological Psychiatry. 87, 5, p. 419-430 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Complement genes contribute sex-biased vulnerability in diverse disorders

Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., Taylor, K. E., Whelan, C. W., Tombleson, P., Loohuis, L. M. O., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H. & 33 others, Pers, Tune H, Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Hansen, M., Hansen, T., Li, T., Olsen, L., Pantelis, C., Rasmussen, H. B., Werge, Thomas, Su, Z., Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case–Control Consortium 2, W. T. C. C. 2., 2020, In: Nature. 582, 7813, p. 577-581 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic liability to ADHD and substance use disorders in individuals with ADHD

Wimberley, T., Agerbo, E., Horsdal, H. T., Ottosen, C., Brikell, I., Als, T. D., Demontis, D., Børglum, A. D., Nordentoft, Merete, Mors, O., Werge, Thomas, Hougaard, D., Bybjerg-Grauholm, J., Hansen, M. B., Mortensen, P. B., Thapar, A., Riglin, L., Langley, K. & Dalsgaard, S., 2020, In: Addiction. 115, 7, p. 1368-1377

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic liability to major depression and risk of childhood asthma

Liu, X., Munk-Olsen, T., Albiñana, C., Vilhjálmsson, B. J., Pedersen, E. M., Schlünssen, V., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Hougaard, D. M., Mortensen, P. B. & Agerbo, E., 2020, In: Brain, Behavior, and Immunity. 89, p. 433-439 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic stratification of depression in UK Biobank

Howard, D. M., Folkersen, L., Coleman, J. R., Adams, M. J., Glanville, K., Werge, Thomas, Hagenaars, S. P., Han, B., Porteous, D., Campbell, A., Clarke, T., Breen, G., Sullivan, P. F., Wray, N. R., Lewis, C. M. & McIntosh, A. M., 2020, In: Translational Psychiatry. 10, 1, 8 p., 163.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study

Erlangsen, A., Appadurai, V., Wang, Y., Turecki, G., Mors, O., Werge, Thomas, Mortensen, P. B., Starnawska, A., Børglum, A. D., Schork, A., Nudel, R., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Thompson, W. K., Nordentoft, Merete & Agerbo, E., 2020, In: Molecular Psychiatry. 25, p. 2410–2421

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth

Wang, Y., Nudel, R., Benros, Michael Eriksen, Skogstrand, K., Fishilevich, S., Lancet, D., Sun, J., Hougaard, D. M., Andreassen, O. A., Mortensen, P. B., Buil, A., Hansen, Thomas Folkmann, Thompson, W. K., Werge, Thomas & iPSYCH-BROAD, I., 2020, In: PLOS Genetics. 16, 11, e1009163.

Research output: Contribution to journal › Journal article › Research › peer-review

Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores

Folkersen, L., Pain, O., Ingason, A., Werge, Thomas, Lewis, C. M. & Austin, J., 2020, In: Frontiers in Genetics. 11, 578.

Research output: Contribution to journal › Journal article › Research › peer-review

Language deficits in specific language impairment, attention deficit/hyperactivity disorder, and autism spectrum disorder: An analysis of polygenic risk

Nudel, R., Christiani, C. A. J., Ohland, J., Uddin, M. J., Hemager, N., Ellersgaard, D. V., Spang, K. S., Burton, B. K., Greve, A. N., Gantriis, D. L., Bybjerg-Grauholm, J., Jepsen, J. R. M., Thorup, Anne, Mors, O., Nordentoft, Merete & Werge, Thomas, 2020, In: Autism Research. 13, 3, p. 369-381

Research output: Contribution to journal › Journal article › Research › peer-review