Thomas Werge

Thomas Werge

Clinical Professor

Member of:

  • Psychiatry


  1. 2015
  2. Published

    Population genetic differentiation of height and body mass index across Europe

    Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., Powell, J. E., Vinkhuyzen, A., Berndt, S. I., Gustafsson, S., Justice, A. E., Kahali, B., Locke, A. E., Pers, T. H., Vedantam, S., Wood, A. R., van Rheenen, W., Andreassen, O. A., Gasparini, P., Metspalu, A. & 23 others, Berg, L. H. V. D., Veldink, J. H., Rivadeneira, F., Werge, Thomas, Abecasis, G. R., Boomsma, D. I., Chasman, D. I., de Geus, E. J. C., Frayling, T. M., Hirschhorn, J. N., Hottenga, J. J., Ingelsson, E., Loos, R. J. F., Magnusson, P. K. E., Martin, N. G., Montgomery, G. W., North, K. E., Pedersen, N. L., Spector, T. D., Speliotes, E. K., Goddard, M. E., Yang, J. & Visscher, P. M., Nov 2015, In: Nature Genetics. 47, 11, p. 1357-62, 2 unpag. Methods 8 p.

    Research output: Contribution to journalLetterResearchpeer-review

  3. Published

    Association Study of CHRNA7 Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study

    Bertelsen, B., Oranje, B., Melchior, L., Fagerlund, Birgitte, Werge, Thomas, Mikkelsen, Jens D., Tümer, Asuman Zeynep & Glenthøj, Birte Yding, Dec 2015, In: NeuroMolecular Medicine. 17, 4, p. 423-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Linkage and whole genome sequencing identify a locus on 6q25-26 for formal thought disorder and implicate MEF2A regulation

    Thygesen, J. H., Zambach, S. K., Ingason, A., Lundin, P., Hansen, T., Bertalan, M., Rosengren, A., Bjerre, D., Ferrero-Miliani, L., Rasmussen, Henrik Berg, Parnas, Josef & Werge, Thomas, Dec 2015, In: Schizophrenia Research. 169, 1-3, p. 441-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family

    Duong, L. T. T., Hoeffding, L. K., Petersen, K. B., Knudsen, C. D., Thygesen, J. H., Klitten, L. L., Tommerup, Niels, Ingason, A. & Werge, Thomas, Dec 2015, In: European Journal of Medical Genetics. 58, 12, p. 650-653 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

    Thompson, W. K., Wang, Y., Schork, A. J., Witoelar, A., Zuber, V., Xu, S., Werge, Thomas, Holland, D., Andreassen, O. A. & Dale, A. M., 29 Dec 2015, In: P L o S Genetics. 11, 12, p. 1-21 21 p., e1005717.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2016
  8. Published

    15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

    Forsingdal, A., Fejgin, K., Nielsen, V., Werge, Thomas & Nielsen, J., 2016, In: Translational Psychiatry. 6, 7, p. 1-9 9 p., e860.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    An epigenetic clock for gestational age at birth based on blood methylation data

    Knight, A. K., Craig, J. M., Theda, C., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Hollegaard, M. V., Hougaard, D. M., Mortensen, P. B., Weinsheimer, S. M., Werge, T. M., Brennan, P. A., Cubells, J. F., Newport, D. J., Stowe, Z. N., Cheong, J. L. Y., Dalach, P., Doyle, L. W., Loke, Y. J., Baccarelli, A. A. & 27 others, Just, A. C., Wright, R. O., Téllez-rojo, M. M., Svensson, K., Trevisi, L., Kennedy, E. M., Binder, E. B., Iurato, S., Czamara, D., Räikkönen, K., Lahti, J. M. T., Pesonen, A., Kajantie, E., Villa, P. M., Laivuori, H., Hämäläinen, E., Park, H. J., Bailey, L. B., Parets, S. E., Kilaru, V., Menon, R., Horvath, S., Bush, N. R., Lewinn, K. Z., Tylavsky, F. A., Conneely, K. N. & Smith, A. K., 2016, In: Genome Biology (Online Edition). 17, 11 p., 206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome

    Vangkilde, A., Jepsen, J. M. R., Schmock, H., Olesen, C., Arnarsdóttir, S., Baaré, W. F. C., Plessen, K. J., Didriksen, M., Siebner, Hartwig Roman, Werge, Thomas & Olsen, L., 2016, In: Journal of Neurodevelopmental Disorders. 8, 13 p., 42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

    Holland, D., Wang, Y., Thompson, W. K., Schork, A. J., Chen, C., Lo, M., Witoelar, A., Werge, Thomas, O'Donovan, M. C., Andreassen, O. A., Dale, A. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 2016, In: Frontiers in Genetics. 7, 13 p., 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., LifeLines Cohort Study, L. C. S., TwinsUK, T. & Werge, Thomas, 2016, In: J A M A Psychiatry. 73, 5, p. 497-505 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

    Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., Grove, J., Maller, J., Samocha, K. E., Sanders, J-S. F., Ripke, S., Martin, J., Hollegaard, M. V., Werge, T., Hougaard, D. M., Neale, B. M., Evans, D. M., Skuse, D., Mortensen, P. B., Børglum, A. D., Ronald, A. & 3 others, Smith, G. D., Daly, M. J. & iPSYCH-SSI-Broad Autism Group, I. A. G., 2016, In: Nature Genetics. 48, 5, p. 552-5 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  14. Published

    Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

    Bigdeli, T. B., Ripke, S., Bacanu, S-A., Lee, S. H., Wray, N. R., Gejman, P. V., Rietschel, M., Cichon, S., St Clair, D., Corvin, A., Kirov, G., McQuillin, A., Gurling, H., Rujescu, D., Andreassen, O. A., Werge, T., Blackwood, D. H. R., Pato, C. N., Pato, M. T., Malhotra, A. K. & 4 others, O'Donovan, M. C., Kendler, K. S., Fanous, A. H. & and Schizophrenia Working Group of the Psychiatric Genomics Consortium, A. S. W. G. O. T. P. G. C., 2016, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 171, 2, p. 276-289 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    High loading of polygenic risk in cases with chronic schizophrenia

    Meier, S. M., Agerbo, E., Maier, R., Pedersen, C. B., Lang, M., Grove, J., Hollegaard, M. V., Demontis, D., Trabjerg, B. B., Hjorthøj, C., Ripke, S., Degenhardt, F., Nöthen, M. M., Rujescu, D., Maier, W., Werge, T., Mors, O., Hougaard, D. M., Børglum, A. D., Wray, N. R. & 5 others, Rietschel, M., Nordentoft, Merete, Mortensen, P. B., Mattheisen, M. & MooDS SCZ Consortium, M. S. C., 2016, In: Molecular Psychiatry. 21, p. 969-974

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA

    Poulsen, J. B., Lescai, F., Grove, J., Bækvad-Hansen, M., Christiansen, M., Hagen, C. M., Maller, J., Stevens, C., Li, S., Li, Q., Sun, J., Wang, J., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Børglum, A. D., Daly, M., Hougaard, D. M., Bybjerg-Grauholm, J. & Hollegaard, M. V., 2016, In: P L o S One. 11, 4, 13 p., e0153253.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders

    Hoeffding, L. K. E., Duong, L. T. T., Ingason, A., Rosengren, A., Sorbanski, E., Witt, S. H., Djurovic, S., Andreassen, O. A., Hansen, T., Werge, Thomas & Rasmussen, Henrik Berg, 2016, In: Nordic Journal of Psychiatry. 70, 4, p. 276-279 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

    Wang, Y., Thompson, W. K., Schork, A. J., Holland, D., Chen, C-H., Bettella, F., Desikan, R. S., Li, W., Witoelar, A., Zuber, V., Devor, A., Nöthen, M. M., Rietschel, M., Chen, Q., Werge, T., Cichon, S., Weinberger, D. R., Djurovic, S., O'Donovan, M. C., Visscher, P. M. & 2 others, Andreassen, O. A. & Dale, A. M., 2016, In: P L o S Genetics. 12, 1, 22 p., e1005803.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample

    Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Association of AADAC Deletion and Gilles de la Tourette Syndrome in a Large European Cohort

    Bertelsen, B., Stefánsson, H., Riff Jensen, L., Melchior, L., Debes, N. M., Groth, C., Skov, L., Werge, T., Karagiannidis, I., Tarnok, Z., Barta, C., Nagy, P., Farkas, L., Brøndum-Nielsen, K., Rizzo, R., Gulisano, M., Rujescu, D., Kiemeney, L. A., Tosato, S., Nawaz, M. S. & 14 others, Ingason, A., Unnsteinsdottir, U., Steinberg, S., Ludvigsson, P., Stefansson, K., Kuss, A. W., Paschou, P., Cath, D., Hoekstra, P. J., Müller-Vahl, K., Stuhrmann, M., Silahtaroglu, Asli, Pfundt, R. & Tümer, Z., 1 Mar 2016, In: Biological Psychiatry. 79, 5, p. 383–391 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders

    Isles, A. R., Ingason, A., Lowther, C., Walters, J. T. R., Gawlick, M., Stöber, G., Rees, E., Martin, J., Little, R. B., Potter, H., Georgieva, L., Pizzo, L., Ozaki, N., Aleksic, B., Kushima, I., Ikeda, M., Iwata, N., Levinson, D. F., Gejman, P. V., Shi, J. & 20 others, Sanders, A. R., Duan, J., Willis, J., Sisodiya, S. M., Costain, G., Werge, Thomas, Degenhardt, F., Giegling, I., Rujescu, D., Hreidarsson, S. J., Saemundsen, E., Ahn, J. W., Ogilvie, C. M., Girirajan, S. D., Stefansson, H., Stefansson, K., O'Donovan, M. C., Owen, M. J., Bassett, A. & Kirov, G., May 2016, In: P L o S Genetics. 12, 5, e1005993.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Schizophrenia Spectrum Disorders in a Danish 22q11.2 Deletion Syndrome Cohort Compared to the Total Danish Population—A Nationwide Register Study

    Vangkilde, A., Olsen, L., Hoeffding, L. K. E., Pedersen, C. B., Mortensen, P. B., Werge, Thomas & Trabjerg, B., May 2016, In: Schizophrenia Bulletin. 42, 3, p. 824-31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The influence of genetic constitution on migraine drug responses

    Christensen, A. F., Esserlind, A., Werge, Thomas, Stefánsson, H., Stefánsson, K. & Olesen, Jes, Jun 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 624-39 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Digital questionnaire platform in the Danish Blood Donor Study

    Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

    Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H. & 31 others, Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes & International Headache Genetics Consortium, I. H. G. C., Aug 2016, In: Nature Genetics. 48, 8, p. 856-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Genetic Markers of Human Evolution Are Enriched in Schizophrenia

    Srinivasan, S., Bettella, F., Mattingsdal, M., Wang, Y., Witoelar, A., Schork, A. J., Thompson, W. K., Zuber, V., Winsvold, B. S., Zwart, J., Collier, D. A., Desikan, R. S., Melle, I., Werge, Thomas, Dale, A. M., Djurovic, S., Andreassen, O. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, S. W. G. O. T. P. G. C. T. I. H. G. C., 15 Aug 2016, In: Biological Psychiatry. 80, 4, p. 284-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

    Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A. D., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D. W., Mowry, B. J., Müller-Mhysok, B., Neale, B. M. & 297 others, Nenadic, I., Nöthen, M. M., O’Dushlaine, C., Rietschel, M., Ruderfer, D. M., Rujescu, D., Schulze, T. G., Simonson, M. A., Stahl, E. A., Strohmaier, J., Witt, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K., Holmans, P. A., Lee, P. H., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, Tune H, Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W. F., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Robert Cloninger, C., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Del-Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Gratten, J., de Haan, L., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Julià, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Chee Keong, J. L., Hong Lee, S., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Mallet, J., Marsal, S., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S. M., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'Callaghan, E., O'Dushlaine, C. T., Anthony O'Neill, F., Oh, S. Y., Olincy, A., Olsen, L., van Os, J., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A. L., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, Henrik Berg, Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Scott Stroup, T., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Watts-Williams, S. J., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Wray, N. R., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Riley, B. P., Sham, P., Sklar, P., St Clair, D., Weinberger, D. R., Wendland, J. R., Werge, Thomas, Daly, M. J., O'Donovan, M. C., Sullivan, P. F. & Keller, M. C., Oct 2016, In: PLOS Genetics. 12, 10, 20 p., e1006343.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The effect of COMT Val158Met genotype on neural response and performance during spatial working memory in remitted patients with bipolar disorder

    Miskowiak, Kamilla, Kjærstad, H. L., Støttrup, M. M., Vinberg, Maj, Carvalho, A. F., Vieta, E., Høffding, L. K., Werge, Thomas, Kessing, Lars Vedel & Macoveanu, J., Oct 2016, In: European Neuropsychopharmacology. 26, Supplement 2, p. S440-S440 1 p., P.2.d.035.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  29. Published

    Investigation of SNP rs2060546 Immediately Upstream to NTN4 in a Danish Gilles de la Tourette Syndrome Cohort

    Padmanabhuni, S. S., Houssari, R., Esserlind, A., Olesen, Jes, Werge, Thomas, Hansen, T. F., Bertelsen, B., Tsetsos, F., Paschou, P. & Tümer, Asuman Zeynep, Nov 2016, In: Frontiers in Neuroscience. 10, 7 p., 531.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2017
  31. Published

    Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry

    Schork, A. J., iPSYCH-SSI-Broad Group, I. G. & Werge, Thomas, 2017, In: Scientific Reports. 7, 11 p., 11380.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

    Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C. & 86 others, van der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, Thomas, Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z., 2017, In: Nature Communications. 8, 11 p., 744.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Comorbidities to restless legs syndrome – results from the Danish blood donor study

    Didriksen, Maria, Hansen, T., Rigas, A., Allen, R., Burchell, B., Thørner, L., Nielsen, K., Di Angelantonio, E., Nielsen, M., Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, O., Paarup, H., Hjalgrim, H., Bruun, M., Burgdorf, K., Sørensen, E. & Ullum, H., 2017, In: Sleep Medicine. 40, Supplement 1, p. E79 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., Gujral, M., Brandler, W. M., Malhotra, D., Wang, Z., Fuentes Fajarado, K. V., Maile, M. S., Ripke, S., Agartz, I., Albus, M., Alexander, M. & 34 others, Amin, F., Atkins, J., Bacanu, S. A., Belliveau, R. A., Bergen, S. E., Bertalan, M., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Bulik-Sullivan, B., Byerley, W., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Cheng, W., Hansen, M., Hansen, T., Olsen, L., Pers, T. H., Rasmussen, H. B., Werge, Thomas, Scherer, S. W., Neale, B. M., Sebat, J. & CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, C. A. S. W. G. O. T. P. G. C., 2017, In: Nature Genetics. 49, 1, p. 27-35

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Evaluation of shared genetic susceptibility loci between autoimmune diseases and schizophrenia based on genome-wide association studies

    Hoeffding, L. K. E., Rosengren, A., Thygesen, J. H., Schmock, H., Werge, Thomas & Hansen, T., 2017, In: Nordic Journal of Psychiatry. 71, 1, p. 20-25 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

    McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C. & 31 others, Sproviero, W., Jones, A. R., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Bauer, D., Kahlke, T., Williams, K., Eftimov, F., Fogh, I., Ticozzi, N., Lin, K., Millecamps, S., Salachas, F., Meininger, V., Carvalho, M. D., Pinto, S., Mora, J. S., Rojas-Garcyá, R., Polak, M., Chandran, S., Andersen, P. M., Pers, Tune H, Hansen, M., Hansen, T., Li, T., Olsen, L., Rasmussen, H. B., Werge, Thomas & Project MinE GWAS Consortium & Schizophrenia Working Group of the Psychiatric Genomics Consortium, P. M. G. C. &. S. W. G. O. T. P. G. C., 2017, In: Nature Communications. 8, 14774.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

    Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 34 others, Bartz, T. M., Trompet, S., Lange, L. A., Raffield, L., van der Spek, A., Galesloot, T. E., Proitsi, P., Yanek, L. R., Bielak, L. F., Payton, A., Murgia, F., Concas, M. P., Biino, G., Tajuddin, S. M., Seppälä, I., Amin, N., Boerwinkle, E., Børglum, A. D., Campbell, A., Demerath, E. W., Demuth, I., Faul, J. D., Ford, I., Gialluisi, A., Gögele, M., Graff, M., Hingorani, A., Hottenga, J., Hougaard, D. M., Werge, Thomas, Esko, T., Kutalik, Z., Wilson, J. F. & et al., E. A., 2017, In: Nature Communications. 8, 13 p., 910.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment

    Le Hellard, S., Wang, Y., Witoelar, A., Zuber, V., Bettella, F., Hugdahl, K., Espeseth, T., Steen, V. M., Melle, I., Desikan, R., Schork, A. J., Thompson, W. K., Dale, A. M., Djurovic, S., Andreassen, O. A., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Ripke, S., Neale, B. M., Corvin, A., Pers, T. H. & 11 others, Agerbo, E., Demontis, D., Hansen, T., Hollegaard, M. V., Hougaard, D. M., Mors, O., Børglum, A. D., Werge, Thomas, Daly, M. J., Sullivan, P. F. & O'Donovan, M. C., 2017, In: Schizophrenia Bulletin. 43, 3, p. 654-664

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility?

    Hilker, R., Helenius, D., Fagerlund, B., Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 2017, In: EBioMedicine. 18, p. 320-326

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: A study in male mice

    Didriksen, M., Fejgin, K., Nilsson, S. R. O., Birknow, M. R., Grayton, H. M., Larsen, P. H., Lauridsen, J. B., Nielsen, V., Celada, P., Santana, N., Kallunki, P., Christensen, K. V., Werge, Thomas, Stensbøl, T. B., Egebjerg, J., Gastambide, F., Artigas, F., Bastlund, J. F. & Nielsen, J., 2017, In: Journal of Psychiatry and Neuroscience. 42, 1, p. 48-58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Severe Parkinsonism and Creatine Kinase Increase After Low-Dose Aripiprazole Treatment in a Patient of African Descent

    Jørgensen, A., Thorleifsson, A., Jimenez-Solem, E., Werge, Thomas & Rasmussen, H. B., 2017, In: Journal of Clinical Psychopharmacology. 37, 5, p. 630-631

    Research output: Contribution to journalLetterResearchpeer-review

  42. Published

    The catechol-O-methyltransferase (COMT) Val158Met genotype modulates working memory-related dorsolateral prefrontal response and performance in bipolar disorder

    Miskowiak, K. W., Kjærstad, H. L., Støttrup, M. M., Svendsen, A. M., Demant, K. M., Hoeffding, L. K., Werge, Thomas, Burdick, K. E., Domschke, K., Carvalho, A. F., Vieta, E., Vinberg, Maj, Kessing, Lars Vedel, Siebner, Hartwig Roman & Macoveanu, J., 2017, In: Bipolar Disorders. 19, 3, p. 214-224 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Nomenclature for alleles of the human carboxylesterase 1 gene

    INDICES Consortium, I. C., 1 Jan 2017, In: Pharmacogenetics and Genomics. 27, 2, p. 78-80 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  44. Published

    Risk of psychiatric disorders among individuals with the 22q11.2 deletion or duplication: A Danish nationwide, register-based study

    Hoeffding, L. K., Trabjerg, B. B., Olsen, L., Mazin, W., Sparsø, T., Vangkilde, A., Mortensen, P. B., Pedersen, C. B. & Werge, Thomas, 1 Mar 2017, In: JAMA Psychiatry. 74, 3, p. 282-290 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register

    Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, Apr 2017, In: EBioMedicine. 18, p. 320-326

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

    Anney, R. J. L., Ripke, S., Anttila, V., Grove, J., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Robinson, E., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Werge, T., Wassink, T. H., Waltes, R. & 143 others, Walsh, C. A., Wallace, S., Vorstman, J. A. S., Vieland, V. J., Vicente, A. M., Vanengeland, H., Tsang, K., Thompson, A. P., Szatmari, P., Svantesson, O., Steinberg, S., Stefansson, K., Stefansson, H., State, M. W., Soorya, L., Silagadze, T., Scherer, S. W., Schellenberg, G. D., Sandin, S., Sanders, S. J., Saemundsen, E., Rouleau, G. A., Rogé, B., Roeder, K., Roberts, W., Reichert, J., Reichenberg, A., Rehnström, K., Regan, R., Poustka, F., Poultney, C. S., Piven, J., Pinto, D., Pericak-Vance, M. A., Pejovic-Milovancevic, M., Pedersen, M. G., Pedersen, C. B., Paterson, A. D., Parr, J. R., Pagnamenta, A. T., Oliveira, G., Nurnberger, J. I., Nordentoft, Merete, Murtha, M. T., Mouga, S., Mortensen, P. B., Mors, O., Morrow, E. M., Moreno-De-Luca, D., Monaco, A. P., Minshew, N., Merikangas, A., McMahon, W. M., McGrew, S. G., Mattheisen, M., Martsenkovsky, I., Martin, D. M., Mane, S. M., Magnusson, P., Magalhaes, T., Maestrini, E., Lowe, J. K., Lord, C., Levitt, P., Martin, C. L., Ledbetter, D. H., Leboyer, M., Lecouteur, A. S., Ladd-Acosta, C., Kolevzon, A., Klauck, S. M., Jacob, S., Iliadou, B., Hultman, C. M., Hougaard, D. M., Hertz-Picciotto, I., Hendren, R., Hansen, C. S., Haines, J. L., Guter, S. J., Grice, D. E., Green, J. M., Green, A., Goldberg, A. P., Gillberg, C., Gilbert, J., Gallagher, L., Freitag, C. M., Fombonne, E., Folstein, S. E., Fernandez, B., Fallin, M. D., Ercan-Sencicek, A. G., Ennis, S., Duque, F., Duketis, E., Delorme, R., Derubeis, S., Dejonge, M. V., Dawson, G., Cuccaro, M. L., Correia, C. T., Conroy, J., Conceição, I. C., Chiocchetti, A. G., Celestino-Soper, P. B. S., Casey, J., Cantor, R. M., Café, C., Bybjerg-Grauholm, J., Brennan, S., Bourgeron, T., Bolton, P. F., Bölte, S., Bolshakova, N., Betancur, C., Bernier, R., Beaudet, A. L., Battaglia, A., Bal, V. H., Baird, G., Bailey, A. J., Bækvad-Hansen, M., Bader, J. S., Bacchelli, E., Anagnostou, E., Amaral, D., Almeida, J., Børglum, A. D., Buxbaum, J. D., Chakravarti, A., Cook, E. H., Coon, H., Geschwind, D. H., Gill, M., Hakonarson, H., Hallmayer, J., Palotie, A., Santangelo, S., Sutcliffe, J. S., Arking, D. E., Devlin, B. & Daly, M. J., 22 May 2017, In: Molecular Autism. 8, 17 p., 21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

    Sapkota, Y., Steinthorsdottir, V., Morris, A. P., Fassbender, A., Rahmioglu, N., De Vivo, I., Buring, J. E., Zhang, F., Edwards, T. L., Jones, S., Dorien, O., Peterse, D., Rexrode, K. M., Ridker, P. M., Schork, A. J., MacGregor, S., Martin, N. G., Becker, C. M., Adachi, S., Yoshihara, K. & 23 others, Enomoto, T., Takahashi, A., Kamatani, Y., Matsuda, K., Kubo, M., Thorleifsson, G., Geirsson, R. T., Thorsteinsdottir, U., Wallace, L. M., Werge, Thomas, Thompson, W. K., Yang, J., Velez Edwards, D. R., Nyegaard, M., Low, S. K., Zondervan, K. T., Missmer, S. A., D'Hooghe, T., Montgomery, G. W., Chasman, D. I., Stefansson, K., Tung, J. Y. & Nyholt, D. R., 24 May 2017, In: Nature Communications. 8, 12 p., 15539.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Lessons to be learned from 22q2.11 syndromes: reply

    Hoeffding, L. K., Pedersen, C. B. & Werge, Thomas, Jul 2017, In: JAMA Psychiatry. 74, 7, p. 757-758 2 p.

    Research output: Contribution to journalComment/debateResearch

  49. Published

    Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

    Weiner, D. J., Wigdor, E. M., Ripke, S., Walters, R. K., Kosmicki, J. A., Grove, J., Samocha, K. E., Goldstein, J. I., Okbay, A., Bybjerg-Grauholm, J., Werge, T., Hougaard, D. M., Taylor, J., Skuse, D., Devlin, B., Anney, R., Sanders, S. J., Bishop, S., Mortensen, P. B., Børglum, A. D. & 32 others, Smith, G. D., Daly, M. J., Robinson, E. B., Bækvad-Hansen, M., Dumont, A., Hansen, C., Hansen, T. F., Howrigan, D., Mattheisen, M., Moran, J., Mors, O., Nordentoft, Merete, Nørgaard-Pedersen, B., Poterba, T., Poulsen, J., Stevens, C., Anttila, V., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Wassink, T. H., Psychiatric Genomics Consortium Autism Group, P. G. C. A. G. & iPSYCH-Broad Autism Group, I. A. G., Jul 2017, In: Nature Genetics. 49, 7, p. 978-985 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Prevalence of restless legs syndrome and associated factors in an otherwise healthy population: results from the Danish Blood Donor Study

    Didriksen, M., Rigas, A. S., Allen, R. P., Burchell, B. J., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., Aug 2017, In: Sleep Medicine. 36, p. 55-61 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Quetiapine extended release versus aripiprazole in children and adolescents with first-episode psychosis: the multicentre, double-blind, randomised tolerability and efficacy of antipsychotics (TEA) trial

    Pagsberg, A. K., Jeppesen, P., Klauber, D. G., Jensen, K. G., Ruda, D., Stentebjerg-Olesen, M., Jantzen, P., Rasmussen, S., Saldeen, E. A-S., Lauritsen, M-B. G., Bilenberg, N., Stenstrom, A. D., Nyvang, L., Madsen, S., Werge, T. M., Lange, T., Gluud, C., Skoog, M., Winkel, P., Jepsen, J. R. M. & 3 others, Fagerlund, Birgitte, Correll, C. U. & Fink-Jensen, Anders, Aug 2017, In: The Lancet Psychiatry. 4, 8, p. 605-618

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome

    Starnawska, A., Hansen, C. S., Sparsø, T., Mazin, W., Olsen, L., Bertalan, M., Buil, A., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mortensen, P. B., Pedersen, C. B., Nyegaard, M., Werge, Thomas & Weinsheimer, S., 29 Aug 2017, In: Translational Psychiatry. 7, 11 p., e1221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission

    Nielsen, J., Fejgin, K., Sotty, F., Nielsen, V., Mørk, A., Christoffersen, C. T., Yavich, L., Lauridsen, J. B., Clausen, D., Larsen, P. H., Egebjerg, J., Werge, Thomas, Kallunki, P., Christensen, K. V. & Didriksen, M., 30 Nov 2017, In: Translational Psychiatry. 7, 12 p., 1261.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 34394780