Thomas Werge
Clinical Professor
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Variation in the purinergic P2RX(7) receptor gene and schizophrenia
Hansen, T., Jakobsen, K. D., Fenger, M., Nielsen, J., Krane, K., Fink-Jensen, Anders, Lublin, H., Ullum, H., Timm, S., Wang, August Gabriel, Jørgensen, Niklas Rye & Werge, Thomas, 2008, In: Schizophrenia Research. 104, 1-3, p. 146-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration
Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A., Rossi, R. M. & 54 others, , 2 Sep 2019, In: Nature Communications. 10, 1, 13 p., 3927.Research output: Contribution to journal › Journal article › Research › peer-review
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Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight
iPSYCH-Broad ASD Group, I. A. G., 15 Apr 2019, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 374, 1770, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Utility and adoption of CYP2D6 and CYP2C19 genotyping and its translation into psychiatric clinical practice
Jürgens, G., Jacobsen, C. B., Rasmussen, H. B., Werge, T., Nordentoft, Merete, Andersen, S. E. & Werge, Thomas, 2012, In: Acta Psychiatrica Scandinavica. 125, 3, p. 228-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Using electronic patient records to discover disease correlations and stratify patient cohorts
Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., Søeby, K., Bredkjær, S., Juul, Anders, Werge, Thomas, Jensen, Lars Juhl & Brunak, Søren, 2011, In: P L o S Computational Biology. 7, 8, p. e1002141 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Usefulness of the SNP microarray technology to identify rare mutations in the case of perinatal death
Hoeffding, L. K., Kock, K. F., Johnsen, I. G., Hansen, Thomas Folkmann & Werge, Thomas, Jan 2015, In: Case Reports in Perinatal Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
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Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S., Andreassen, O. A., Werge, T., Hall, H., Agartz, I., Terenius, L., Jönsson, E. G., Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S. & 6 others, , 2009, In: Psychiatric Genetics. 19, 5, p. 273-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family
Duong, L. T. T., Hoeffding, L. K., Petersen, K. B., Knudsen, C. D., Thygesen, J. H., Klitten, L. L., Tommerup, Niels, Ingason, A. & Werge, Thomas, Dec 2015, In: European Journal of Medical Genetics. 58, 12, p. 650-653 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
Jönsson, E. G., Larsson, K., Vares, M., Hansen, T., Wang, August Gabriel, Djurovic, S., Rønningen, K. S., Andreassen, O. A., Agartz, I., Werge, Thomas, Terenius, L. & Hall, H., 2008, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 147B, 6, p. 976-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 30 Dec 2010, In: Psychiatry Research. 180, 2-3, p. 63-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Triton X-100 inhibits agonist-induced currents and suppresses benzodiazepine modulation of GABA(A) receptors in Xenopus oocytes
Søgaard, R., Ebert, B., Klærke, Dan Arne, Werge, Thomas, Søgaard, R., Ebert, B., Klaerke, D. & Werge, Thomas, 2009, In: B B A - Biomembranes. 1788, 5, p. 1073-80 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction
Sun, J., Wang, Y., Folkersen, L., Borné, Y., Amlien, I., Buil, A., Orho-Melander, M., Børglum, A. D., Hougaard, D. M., Lotta, L. A., Jones, M., Baras, A., Melander, O., Engström, G., Werge, Thomas, Lage, K. & Regeneron Genetics Center, R. G. C., 2021, In: Nature Communications. 12, 5276.Research output: Contribution to journal › Journal article › Research › peer-review
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Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome
Lahrouchi, N., Tadros, R., Crotti, L., Mizusawa, Y., Postema, P. G., Beekman, L., Walsh, R., Hasegawa, K., Barc, J., Ernsting, M., Turkowski, K. L., Mazzanti, A., Beckmann, B. M., Shimamoto, K., Diamant, U-B., Wijeyeratne, Y. D., Kucho, Y., Robyns, T., Ishikawa, T., Arbelo, E. & 86 others, , 2020, In: Circulation. 142, 4, p. 324-338Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations
Gordon, A., Forsingdal, A., Klewe, I. V., Nielsen, J., Didriksen, M., Werge, Thomas & Geschwind, D. H., 2021, In: Molecular Psychiatry. 26, p. 1520–1534Research output: Contribution to journal › Journal article › Research › peer-review
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Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia
van Schijndel, J. E., van Loo, K. M. J., van Zweeden, M., Djurovic, S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kallunki, P., Pedersen, J. T. & Martens, G. J. M., 2009, In: Journal of Psychiatric Research. 43, 15, p. 1195-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
Saetre, P., Lundmark, P., Wang, August Gabriel, Hansen, Thomas Folkmann, Rasmussen, Henrik Berg, Djurovic, S., Melle, I., Andreassen, O. A., Werge, Thomas, Agartz, I., Hall, H., Terenius, L. & Jönsson, E. G., 5 Mar 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 2, p. 387-96 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The substituted (S)-3-phenylpiperidine (-)-OSU6162 reduces apomorphine- and amphetamine-induced behaviour in Cebus apella monkeys
Brandt-Christensen, M., Andersen, M. B., Fink-Jensen, Anders, Werge, Thomas & Gerlach, J., 2006, In: Journal of Neural Transmission. 113, 1, p. 11-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The sequences of 150,119 genomes in the UK Biobank
Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F., Asgeirsdottir, M. & 27 others, , 2022, In: Nature. 607Research output: Contribution to journal › Journal article › Research › peer-review
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The prevalence and early life determinants of mental disorders in school aged children: 11 years follow up of the CCC 2000 birth cohort study. Poster presentation XVII.ESCAP International Congress Budapest August 2009
Jeppesen, Pia, Fagerlund, Birgitte, Glenthøj, Birte Yding, Werge, Thomas, Linneberg, Allan René, Jørgensen, T. & Skovgaard, A. M., 2009. 0 p.Research output: Contribution to conference › Poster › Research › peer-review
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The population genomic legacy of the second plague pandemic
Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, , 2022, In: Current Biology. 32, 21, p. 4743-4751.e6Research output: Contribution to journal › Journal article › Research › peer-review
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The muscarinic M1/M4 receptor agonist xanomeline exhibits antipsychotic-like activity in Cebus apella monkeys
Andersen, M. B., Fink-Jensen, Anders, Peacock, L., Gerlach, J., Bymaster, F., Lundbaek, J. A. & Werge, Thomas, 2003, In: Neuropsychopharmacology. 28, 6, p. 1168-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The influence of genetic constitution on migraine drug responses
Christensen, A. F., Esserlind, A., Werge, Thomas, Stefánsson, H., Stefánsson, K. & Olesen, Jes, Jun 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 624-39 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of CYP2D6 and CYP2C19 polymorphisms on suicidal behavior and substance abuse disorder among patients with schizophrenia: a retrospective study
Kobylecki, C. J., Hansen, T., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Sørensen, H. J., Rasmussen, H. B., Werge, T. M., Kobylecki, C. J., Hansen, T. F., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Sørensen, H. J., Rasmussen, H. B. & Werge, Thomas, 2008, In: Therapeutic Drug Monitoring. 30, 3, p. 265-70 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders
Pedersen, C. B., Bybjerg-Grauholm, J., Pedersen, M. G., Grove, J., Agerbo, E., Bækvad-Hansen, M., Poulsen, J. B., Hansen, C. S., McGrath, J. J., Als, T. D., Goldstein, J. I., Neale, B. M., Daly, M. J., Hougaard, D. M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Mortensen, P. B., 2018, In: Molecular Psychiatry. 23, p. 6-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The genetic structure of Norway
Mattingsdal, M., Ebenesersdóttir, S. S., Moore, K. H. S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kockum, I., Olsson, T., Alfredsson, L., Helgason, A., Stefánsson, K. & Hovig, E., 2021, In: European Journal of Human Genetics. 29, p. 1710–1718Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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590
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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340
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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