Thomas Werge
Clinical Professor
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Genetic disposition towards educational attainment and intelligence test performance predict voter turnout
Aaroe, L., Appadurai, V., Hansen, Kasper Møller, Schork, A. J., Werge, Thomas, Mors, O., Borglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Thompson, W. K., Buil, A., Agerbo, E. & Petersen, M. B., 2021, In: Nature Human Behavior. 5, 2, p. 281-291 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A comprehensive family-based replication study of schizophrenia genes
Aberg, K. A., Liu, Y., Bukszár, J., McClay, J. L., Khachane, A. N., Andreassen, O. A., Blackwood, D., Corvin, A., Djurovic, S., Gurling, H., Ophoff, R., Pato, C. N., Pato, M. T., Riley, B., Webb, T., Kendler, K., O'Donovan, M., Craddock, N., Kirov, G., Owen, M. & 7 others, , 1 Feb 2013, In: JAMA psychiatry (Chicago, Ill.). 70, 2, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status
Agerbo, E., Trabjerg, B. B., Børglum, A. D., Schork, A. J., Vilhjálmsson, B. J., Pedersen, C. B., Hakulinen, C., Albiñana, C., Hougaard, D. M., Grove, J., McGrath, J. J., Bybjerg-Grauholm, J., Mors, O., Plana-Ripoll, O., Werge, Thomas, Wray, N. R., Mortensen, P. B. & Musliner, K. L., 2021, In: JAMA Psychiatry. 78, 4, p. 387-397 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses
Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, , 2020, In: Nature Communications. 11, 12 p., 6398.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-PGS enhances polygenic prediction by combining 937 polygenic scores
Albiñana, C., Zhu, Z., Schork, A. J., Ingason, A., Aschard, H., Brikell, I., Bulik, C. M., Petersen, L. V., Agerbo, E., Grove, J., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., McGrath, J. J., Neale, B. M., Privé, F. & Vilhjálmsson, B. J., 2023, In: Nature Communications. 14, 11 p., 4702.Research output: Contribution to journal › Journal article › Research › peer-review
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Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction
Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J., 2021, In: American Journal of Human Genetics. 108, 6, p. 1001-1011 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., Vilhjálmsson, B. J. & 1 others, , 2023, In: Nature Communications. 14, 16 p., 852.Research output: Contribution to journal › Journal article › Research › peer-review
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Population Genomics of Stone Age Eurasia
Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., Mota, B., Paulsson, B. S., Halgren, A., Macleod, R., Schjellerup Jørkov, M. L., Demeter, F., Novosolov, M., Sørensen, L., Nielsen, P-O., Henriksen, R. H. A. & 143 others, , 2022, p. 1-71, (bioRxiv).Research output: Working paper › Preprint › Research
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100 ancient genomes show repeated population turnovers in Neolithic Denmark
Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, , 2024, In: Nature. 625, 7994, p. 329-337 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Population genomics of post-glacial western Eurasia
Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., da Mota, B. S., Paulsson, B. S., Halgren, A., Macleod, R., Jørkov, M. L. S., Demeter, F., Sørensen, L., Nielsen, P. O., Henriksen, R. A., Vimala, T. & 144 others, , 2024, In: Nature. 625, 7994, p. 301-311Research output: Contribution to journal › Journal article › Research › peer-review
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Deep Learning for Cross-Diagnostic Prediction of Mental Disorder Diagnosis and Prognosis Using Danish Nationwide Register and Genetic Data
Allesøe, R. L., Thompson, W. K., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2023, In: JAMA Psychiatry. 80, 2, p. 146-155 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression
Allesøe, R. L., Nudel, R., Thompson, W. K., Wang, Y., Nordentoft, Merete, Børglum, A. D., Hougaard, D. M., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2022, In: Science Advances. 8, 26, eabi7293.Research output: Contribution to journal › Journal article › Research › peer-review
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Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses
Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G., Thorgeirsson, T. & 23 others, , 2023, In: Nature Medicine. 29, 7, p. 1832-1844 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 46 others, , 2021, In: Molecular Psychiatry. 26, p. 2457–2470 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The adenosine A2A receptor agonist CGS 21680 exhibits antipsychotic-like activity in Cebus apella monkeys
Andersen, M. B., Fuxe, K., Werge, Thomas & Gerlach, J., 2002, In: Behavioural Pharmacology. 13, 8, p. 639-44 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The muscarinic M1/M4 receptor agonist xanomeline exhibits antipsychotic-like activity in Cebus apella monkeys
Andersen, M. B., Fink-Jensen, Anders, Peacock, L., Gerlach, J., Bymaster, F., Lundbaek, J. A. & Werge, Thomas, 2003, In: Neuropsychopharmacology. 28, 6, p. 1168-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates
Andersen, M. B., Croy, C. H., Dencker, D., Werge, Thomas, Bymaster, F. P., Felder, C. C. & Fink-Jensen, Anders, 2015, In: PLOS ONE. 10, 4, p. 1-13 13 p., e0122722.Research output: Contribution to journal › Journal article › Research › peer-review
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Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, , 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
Andreassen, O. A., Thompson, W. K., Schork, A. J., Ripke, S., Mattingsdal, M., Kelsoe, J. R., Kendler, K. S., O'Donovan, M. C., Rujescu, D., Werge, Thomas, Sklar, P., Roddey, J. C., Chen, C., McEvoy, L., Desikan, R. S., Djurovic, S., Dale, A. M. & Psychiatric Genomics Consortium (PGC), P. G. C. (., Apr 2013, In: P L o S Genetics (Online). 9, 4, p. e1003455Research output: Contribution to journal › Journal article › Research › peer-review
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Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors
Andreassen, O. A., Djurovic, S., Thompson, W. K., Schork, A. J., Kendler, K. S., O'Donovan, M. C., Rujescu, D., Werge, Thomas, van de Bunt, M., Morris, A. P., McCarthy, M. I., Roddey, J. C., McEvoy, L. K., Desikan, R. S., Dale, A. M. & International Consortium for Blood Pressure GWAS, I. C. F. B. P. G., Feb 2013, In: American Journal of Human Genetics. 92, 2, p. 197-209 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
Andreou, D., Saetre, P., Kähler, A. K., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., Sep 2011, In: European Neuropsychopharmacology. 21, 9, p. 700-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S., Andreassen, O. A., Werge, T., Hall, H., Agartz, I., Terenius, L., Jönsson, E. G., Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S. & 6 others, , 2009, In: Psychiatric Genetics. 19, 5, p. 273-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 2012, In: European Archives of Psychiatry and Clinical Neuroscience. 262, 7, p. 549-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 30 Dec 2010, In: Psychiatry Research. 180, 2-3, p. 63-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Anney, R. J. L., Ripke, S., Anttila, V., Grove, J., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Robinson, E., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Werge, T., Wassink, T. H., Waltes, R. & 143 others, , 22 May 2017, In: Molecular Autism. 8, 17 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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588
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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340
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
Published