Thomas Werge

Thomas Werge

Clinical Professor

Member of:

  • Psychiatry


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  1. Published

    100 ancient genomes show repeated population turnovers in Neolithic Denmark

    Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, Irving-Pease, Evan, Barrie, William, Pearson, A., Sousa da Mota, B., Demeter, Fabrice, Henriksen, Rasmus Henrik Amund, Vimala, Tharsika, McColl, Hugh, Vaughn, Andrew Howland, Vinner, Lasse, Renaud, Gabriel, Stern, A., Johannsen, N. N., Ramsøe, Abigail Daisy, Schork, A. J., Ruter, Anthony Henry, Gotfredsen, Anne Birgitte, Nielsen, B. H., Petersen, Erik Brinch, Kannegaard, E., Hansen, J., Pedersen, K. B., Pedersen, L., Klassen, L., Meldgaard, Morten, Johansen, M., Uldum, O. C., Lotz, P., Lysdahl, P., Bangsgaard, Pernille, Petersen, P. V., Maring, R., Iversen, Rune, Wåhlin, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Lynnerup, Niels, Lawson, D. J., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Kjær, Kurt H., Durbin, R., Nielsen, Rasmus, Delaneau, O., Werge, Thomas, Kristiansen, Kristian & Willerslev, Eske, 2024, In: Nature. 625, 7994, p. 329-337 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

    Forsingdal, A., Fejgin, K., Nielsen, V., Werge, Thomas & Nielsen, J., 2016, In: Translational Psychiatry. 6, 7, p. 1-9 9 p., e860.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response

    Larsen, K. M., Pellegrino, G., Birknow, M. R., Kjær, T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Mørup, M. & Siebner, Hartwig Roman, 2018, In: Schizophrenia Bulletin. 44, 2, p. 388–397

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

    Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Agerbo, E., Gern, J. E., Lemanske, R. F., Ober, C., Pedersen, A. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Nature Communications. 11, 12 p., 6398.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

    Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., Brikell, I., Ghirardi, L., Larsson, H., Lichtenstein, P., Eriksson, N., 23andMe Research Team, 2. R. T., Psychiatric Genomics Consortium: ADHD Subgroup, P. G. C. A. S., iPSYCH–Broad ADHD Workgroup, I. A. W., Werge, Thomas & Nordentoft, Merete, 15 Jun 2018, In: Biological Psychiatry. 83, 12, p. 1044-1053 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A closed-tube assay for genotyping of the 32-bp deletion polymorphism in the chemokine receptor 5 (CCR5) gene: dissociation analysis of amplified fragments of DNA

    Rasmussen, H. B. & Werge, Thomas, 2007, In: Molecular and Cellular Probes. 21, 1, p. 8-11 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A comprehensive family-based replication study of schizophrenia genes

    Aberg, K. A., Liu, Y., Bukszár, J., McClay, J. L., Khachane, A. N., Andreassen, O. A., Blackwood, D., Corvin, A., Djurovic, S., Gurling, H., Ophoff, R., Pato, C. N., Pato, M. T., Riley, B., Webb, T., Kendler, K., O'Donovan, M., Craddock, N., Kirov, G., Owen, M. & 7 others, Rujescu, D., St Clair, D., Werge, Thomas, Hultman, C. M., Delisi, L. E., Sullivan, P. & van den Oord, E. J., 1 Feb 2013, In: JAMA psychiatry (Chicago, Ill.). 70, 2, p. 1-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

    Athanasiadis, G., Meijsen, J. J., Helenius, D., Schork, A. J., Ingason, A., Thompson, W. K., Geschwind, D. H., Werge, Thomas & Buil, A., 2022, In: PNAS. 119, 6, 9 p., e2118688119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions

    Nudel, R., Zetterberg, R., Hemager, N., Christiani, C. A. J., Ohland, J., Burton, B. K., Greve, A. N., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Bybjerg-Grauholm, J., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Mors, O. & Nordentoft, Merete, 2022, In: Behavioral and Brain Functions. 18, 14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

    Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D., Bo Mortensen, P. & 4 others, Buil, A., Thompson, W. K., Geschwind, D. H. & Werge, Thomas, Mar 2019, In: Nature Neuroscience. 22, 3, p. 353-361

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

    Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, The International Headache Genetics Consortium, T. I. H. G. C. & the 23andMe Research Team, T. 2. R. T., 2020, In: Nature Communications. 11, 1, 3368.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

    Bell, S., Rigas, A. S., Magnusson, M. K., Ferkingstad, E., Allara, E., Bjornsdottir, G., Ramond, A., Sørensen, E., Halldorsson, G. H., Paul, D. S., Burgdorf, K. S., Eggertsson, H. P., Howson, J. M. M., Thørner, L. W., Kristmundsdottir, S., Astle, W. J., Erikstrup, C., Sigurdsson, J. K., Vuckovic, D., Dinh, K. M. & 31 others, Tragante, V., Surendran, P., Pedersen, Ole Birger Vesterager, Vidarsson, B., Jiang, T., Paarup, H. M., Onundarson, P. T., Akbari, P., Nielsen, K. R., Lund, S. H., Juliusson, K., Magnusson, M. I., Frigge, M. L., Oddsson, A., Olafsson, I., Kaptoge, S., Hjalgrim, Henrik, Runarsson, G., Wood, A. M., Hansen, Thomas Folkmann, Burgdorf, Kristoffer Sølvsten, Jemec, Gregor, Jennum, Poul, Nielsen, K. R., Petersen, M., Werge, Thomas, Westergaard, David, Banasik, Karina, Brunak, Søren, Ullum, H. & DBDS Genomic Consortium, D. G. C., 2021, In: Communications Biology . 4, 1, 14 p., 156.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness

    Nudel, R., Appadurai, V., Schork, A. J., Buil, A., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, Mar 2020, In: Human Genetics. 139, p. 593-604

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia

    Ingason, A., Giegling, I., Cichon, S., Hansen, T., Rasmussen, H. B., Nielsen, J., Jürgens, G., Muglia, P., Hartmann, A. M., Strengman, E., Vasilescu, C., Mühleisen, T. W., Djurovic, S., Melle, I., Lerer, B., Möller, H-J., Francks, C., Pietiläinen, O. P. H., Lonnqvist, J., Suvisaari, J. & 21 others, Tuulio-Henriksson, A., Walshe, M., Vassos, E., Di Forti, M., Murray, R., Bonetto, C., Tosato, S., Cantor, R. M., Rietschel, M., Craddock, N., Owen, M. J., Peltonen, L., Andreassen, O. A., Nöthen, M. M., St Clair, D., Ophoff, R. A., O'Donovan, M. C., Collier, D. A., Werge, Thomas, Rujescu, D. & GROUP Investigators, G. I., 1 Apr 2010, In: Human Molecular Genetics. 19, 7, p. 1379-86 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A large-scale genome-wide association study meta-analysis of cannabis use disorder

    Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., Sanchez-Roige, S., Paul, S. E., Wendt, F. R., Clarke, T. K., Lai, D., Reginsson, G. W., Zhou, H., He, J., Baranger, D. A. A., Gudbjartsson, D. F., Wedow, R., Adkins, D. E., Adkins, A. E., Alexander, J. & 31 others, Bacanu, S. A., Bigdeli, T. B., Boden, J., Brown, S. A., Bucholz, K. K., Bybjerg-Grauholm, J., Corley, R. P., Degenhardt, L., Dick, D. M., Domingue, B. W., Fox, L., Goate, A. M., Gordon, S. D., Hack, L. M., Hancock, D. B., Hartz, S. M., Hickie, I. B., Hougaard, D. M., Krauter, K., Lind, P. A., McClintick, J. N., McQueen, M. B., Meyers, J. L., Montgomery, G. W., Mors, O., Mortensen, P. B., Nordentoft, Merete, Pearson, J. F., Peterson, R. E., Werge, Thomas & Psychiatric Genomics Consortium Substance Use Disorders Workgroup, P. G. C. S. U. D. W., 2020, In: The Lancet Psychiatry. 7, 12, p. 1032-1045 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

    Nudel, R., Wang, Y., Appadurai, V., Schork, A. J., Buil, A., Agerbo, E., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, 2019, In: Translational Psychiatry. 9, 1, 10 p., 283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders

    Nudel, R., Allesøe, R. L., Thompson, W. K., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2021, In: Journal of Translational Medicine. 19, 230.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A major role for common genetic variation in anxiety disorders

    Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O., Bo Mortensen, P. & 6 others, Nordentoft, Merete, Werge, Thomas, Nicodemus, K. K., Mattheisen, M., Breen, G. & Eley, T. C., 2020, In: Molecular Psychiatry. 25, p. 3292–3303

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission

    Nielsen, J., Fejgin, K., Sotty, F., Nielsen, V., Mørk, A., Christoffersen, C. T., Yavich, L., Lauridsen, J. B., Clausen, D., Larsen, P. H., Egebjerg, J., Werge, Thomas, Kallunki, P., Christensen, K. V. & Didriksen, M., 30 Nov 2017, In: Translational Psychiatry. 7, 12 p., 1261.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

    Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. K., Adams, M. J., Clarke, T. K., McIntosh, A. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M. & 31 others, Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Hansen, C. S., Hansen, T. F., Pedersen, C. B., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Nature Communications. 11, 1, 2301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A polygenic resilience score moderates the genetic risk for schizophrenia

    Hess, J. L., Tylee, D. S., Mattheisen, M., The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum, A. D., Als, T. D., Grove, J., Werge, T., Mortensen, P. B., Mors, O., Nordentoft, M., Hougaard, D. M., Byberg-grauholm, J., Bækvad-hansen, M., Greenwood, T. A., Tsuang, M. T., Curtis, D., Steinberg, S., Sigurdsson, E. & 6 others, Stefánsson, H., Stefánsson, K., Edenberg, H. J., Holmans, P., Faraone, S. V. & Glatt, S. J., 2021, In: Molecular Psychiatry. 26, p. 800–815

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)

    Djurovic, S., Kähler, A. K., Kulle, B., Jönsson, E. G., Agartz, I., Le Hellard, S., Hall, H., Jakobsen, K. D., Hansen, T., Melle, I., Werge, T., Steen, V. M., Andreassen, O. A., Djurovic, S., Kähler, A. K., Kulle, B., Jönsson, E. G., Agartz, I., Le Hellard, S., Hall, H. & 6 others, Jakobsen, K. D., Hansen, T. F., Melle, I., Werge, Thomas, Steen, V. M. & Andreassen, O. A., 2009, In: Schizophrenia Research. 107, 2-3, p. 242-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A rare variant in MYH6 is associated with high risk of sick sinus syndrome

    Holm, H., Gudbjartsson, D. F., Sulem, P., Masson, G., Helgadottir, H. T., Zanon, C., Magnusson, O. T., Helgason, A., Saemundsdottir, J., Gylfason, A., Stefansdottir, H., Gretarsdottir, S., Matthiasson, S. E., Thorgeirsson, G. M., Jonasdottir, A., Sigurdsson, A., Stefansson, H., Werge, T., Rafnar, T., Kiemeney, L. A. & 10 others, Parvez, B., Muhammad, R., Roden, D. M., Darbar, D., Thorleifsson, G., Walters, G. B., Kong, A., Thorsteinsdottir, U., Arnar, D. O. & Stefansson, K., 1 Apr 2011, In: Nature Genetics. 43, 4, p. 316-20 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A saturated map of common genetic variants associated with human height

    Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, J., Møllehave, Line Tang, Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, Niels, Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A study of the genetic architecture of social responsiveness in families with parental schizophrenia or bipolar disorder and population-based controls

    Veddum, L., Greve, A. N., Gregersen, M., Andreassen, A. K., Knudsen, C. B., Brandt, J. M., Krantz, M. F., Søndergaard, A., Burton, B. K., Jepsen, J. R. M., Hemager, N., Werge, Thomas, Thorup, Anne, Nordentoft, Merete, Mors, O. & Nudel, R., 2023, In: Psychiatry Research. 326, 115280.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 34394780