Thomas Werge

Thomas Werge

Clinical Professor

Member of:

  • Psychiatry


  1. 2021
  2. Published

    Identification of genetic loci associated with nocturnal enuresis: a genome-wide association study

    Jørgensen, C. S., Horsdal, H. T., Rajagopal, V. M., Grove, J., Als, T. D., Kamperis, K., Nyegaard, M., Walters, G. B., Eðvarðsson, V. Ö., Stefánsson, H., Nordentoft, M., Hougaard, D. M., Werge, T., Mors, O., Mortensen, P. B., Agerbo, E., Rittig, S., Stefánsson, K., Børglum, A. D., Demontis, D. & 1 others, Christensen, J. H., 2021, In: The Lancet Child & Adolescent Health. 5, 3, p. 201-209

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease

    Herborg, F., Jensen, K. L., Tolstoy, S., Arends, N., Posselt, L. P., Shekar, A., Aguilar, J., Lund, V. K., Erreger, K., Rickhag, M., Lycas, M. D., Lonsdale, M. N., Rahbek-Clemmensen, T., Sorensen, A. T., Newman, A. H., Lokkegaard, A., Kjaerulff, O., Werge, T., Moller, L. B., Matthies, H. J. G. & 4 others, Galli, A., Hjermind, L. E., Gether, Ulrik & IPSYCH Researchers, I. R., 2021, In: JCI insight. 6, 18, 21 p., 151496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life - A Large Prospective Cohort Study on Adult Danes

    Didriksen, Maria, Werge, Thomas, Nissen, J., Schwinn, M., Sørensen, E., Nielsen, K. R., Bruun, M. T., Banasik, Karina, Hansen, T. F., Erikstrup, C., Ostrowski, Sisse Rye, Jennum, Poul, Hjalgrim, Henrik, Ullum, H. & Pedersen, Ole Birger Vesterager, 2021, In: International Journal of Environmental Research and Public Health. 18, 14, 14 p., 7610.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Is the Association between Parents' Mental Illness and Child Psychopathology Mediated via Home Environment and Caregiver's Psychosocial Functioning? A Mediation Analysis of the Danish High Risk and Resilience Study-VIA7, a Population-Based Cohort Study

    Uddin, M. J., Ekstrøm, C. T., Hemager, N., Christiani, C. A. J., Gregersen, M., Ellersgaard, D. V., Spang, K. S., Greve, A., Burton, B. K., Søndergaard, A., Nudel, R., Mortensen, P. B., Pedersen, M. G., Pedersen, C. B., Wang, Y., Werge, T., Bybjerg-Grauholm, J., Von Plessen, K. J., Bliksted, V., Mors, O. & 2 others, Thorup, Anne & Nordentoft, Merete, 2021, In: Schizophrenia Bulletin Open. 2, 1, 12 p., sgab024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction

    Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J., 2021, In: American Journal of Human Genetics. 108, 6, p. 1001-1011 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    No evidence of associations between genetic liability for schizophrenia and development of cannabis use disorder

    Hjorthøj, Carsten, Uddin, M. J., Wimberley, T., Dalsgaard, S., Hougaard, D. M., Borglum, A., Werge, Thomas & Nordentoft, Merete, 2021, In: Psychological Medicine. 51, 3, p. 479-484 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Pharmacogenetic genotype and phenotype frequencies in a large Danish population-based case-cohort sample

    Lunenburg, C. A. T. C., Thirstrup, J. P., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Børglum, A. D., Mors, O., Mortensen, P. B. & Gasse, C., 2021, In: Translational Psychiatry. 11, 1, 294.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants

    Nudel, R., Appadurai, V., Buil, A., Nordentoft, Merete & Werge, Thomas, 2021, In: Journal of Neurodevelopmental Disorders. 13, 15 p., 54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis

    Strom, N. I., Grove, J., Meier, S. M., Bækvad-Hansen, M., Becker Nissen, J., Damm Als, T., Halvorsen, M., Nordentoft, Merete, Mortensen, P. B., Hougaard, D. M., Werge, Thomas, Mors, O., Børglum, A. D., Crowley, J. J., Bybjerg-Grauholm, J. & Mattheisen, M., 2021, In: Frontiers in Genetics. 12, 711624.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Relationship Between Major Depressive Disorder (Mdd) Symptoms and Mdd Heterogeneity

    Huang, L., Tang, S., Krebs, M. D., Schork, A. J., Werge, Thomas, Dahl, A., Zuber, V. & Cai, N., 2021, In: Genetic Epidemiology. 45, 7, p. 761-761 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  12. Published

    Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status

    Agerbo, E., Trabjerg, B. B., Børglum, A. D., Schork, A. J., Vilhjálmsson, B. J., Pedersen, C. B., Hakulinen, C., Albiñana, C., Hougaard, D. M., Grove, J., McGrath, J. J., Bybjerg-Grauholm, J., Mors, O., Plana-Ripoll, O., Werge, Thomas, Wray, N. R., Mortensen, P. B. & Musliner, K. L., 2021, In: JAMA Psychiatry. 78, 4, p. 387-397 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

    Demontis, D., Walters, R. K., Rajagopal, V. M., Waldman, I. D., Grove, J., Als, T. D., Dalsgaard, S., Ribasas, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T., Nordentoft, M., Mors, O., Mortensen, P. B., Andreassen, O. A., Arranz, M. J., Banaschewski, T., Bau, C., Bellgrove, M., Biederman, J. & 31 others, Brikell, I., Buitelaar, J. K., Burton, C. L., Casas, M., Crosbie, J., Doyle, A. E., Ebstein, R. P., Elia, J., Elizabeth, C. C., Grevet, E., Grizenko, N., Havdahl, A., Hawi, Z., Hebebrand, J., Hervas, A., Hohmann, S., Haavik, J., Joober, R., Kent, L., Kuntsi, J., Langley, K., Larsson, Henrik Bo Wiberg, Lesch, K. P., Leung, P. W. L., Liao, C., Loo, S. K., Martin, J., Martin, N. G., Medland, S. E., Miranda, A. & ADHD Working Group of the Psychiatric Genomics Consortium (PGC), A. W. G. O. T. P. G. C. (., 2021, In: Nature Communications. 12, 576.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The genetic structure of Norway

    Mattingsdal, M., Ebenesersdóttir, S. S., Moore, K. H. S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kockum, I., Olsson, T., Alfredsson, L., Helgason, A., Stefánsson, K. & Hovig, E., 2021, In: European Journal of Human Genetics. 29, p. 1710–1718

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations

    Gordon, A., Forsingdal, A., Klewe, I. V., Nielsen, J., Didriksen, M., Werge, Thomas & Geschwind, D. H., 2021, In: Molecular Psychiatry. 26, p. 1520–1534

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction

    Sun, J., Wang, Y., Folkersen, L., Borné, Y., Amlien, I., Buil, A., Orho-Melander, M., Børglum, A. D., Hougaard, D. M., Lotta, L. A., Jones, M., Baras, A., Melander, O., Engström, G., Werge, Thomas, Lage, K. & Regeneron Genetics Center, R. G. C., 2021, In: Nature Communications. 12, 5276.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2020
  18. Published

    Effect of Routine Cytochrome P450 2D6 and 2C19 Genotyping on Antipsychotic Drug Persistence in Patients With Schizophrenia: A Randomized Clinical Trial

    Jürgens, Gesche, Andersen, Stig Ejdrup, Rasmussen, H. B., Werge, Thomas, Jensen, H. D., Kaas-Hansen, Benjamin Skov & Nordentoft, Merete, 1 Dec 2020, In: JAMA Network Open. 3, 12, p. e2027909

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Influence of the genetic liability on the association between infections and autism

    Shorter, J., Krebs, M., Ingason, A., Benros, Michael Eriksen, Thompson, W. & Werge, Thomas, Dec 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 719-720 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  20. Published

    Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

    Bryois, J., Skene, N. G., Hansen, T. F., Kogelman, L. J. A., Watson, H. J., Liu, Z., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan, R., Alfredsson, L., Ando, T., Andreassen, O., Baker, J., Bergen, A., Berrettini, W., Birgegård, A., Boden, J., Boehm, I., Boni, C., Boraska Perica, V., Brandt, H. & 44 others, Breen, G., Bryois, J., Buehren, K., Bulik, C., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Coleman, J., Cone, R., Courtet, P., Crawford, S., Crow, S., Crowley, J., Danner, U., Davis, O., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J., Dick, D., Hinney, A., Grove, J., Larsen, J., Mattheisen, M., Mortensen, P. B., Petersen, L., Werge, Thomas, Zeggini, E., Zerwas, S., Zipfel, S., International Headache Genetics Consortium, I. H. G. C., Anttila, V., Artto, V., Belin, A. C., Christensen, A. F., Esserlind, A., Kogelman, L. J. A., Olesen, Jes, Olesen, Jes, Winsvold, B. S., Zhao, H., Zwart, J. & 23andMe Research Team, 2. R. T., May 2020, In: Nature Genetics. 52, p. 482-493

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

    Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 31 others, Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Hansen, C. S., Hansen, T. F., Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete, Werge, Thomas & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, O. T. B. O. M. D. D. W. G. O. T. P. G. C., May 2020, In: Molecular Psychiatry. 25, p. 1430-1446

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness

    Nudel, R., Appadurai, V., Schork, A. J., Buil, A., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, Mar 2020, In: Human Genetics. 139, p. 593-604

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

    Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Agerbo, E., Gern, J. E., Lemanske, R. F., Ober, C., Pedersen, A. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Nature Communications. 11, 12 p., 6398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

    Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, The International Headache Genetics Consortium, T. I. H. G. C. & the 23andMe Research Team, T. 2. R. T., 2020, In: Nature Communications. 11, 1, 3368.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A large-scale genome-wide association study meta-analysis of cannabis use disorder

    Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., Sanchez-Roige, S., Paul, S. E., Wendt, F. R., Clarke, T. K., Lai, D., Reginsson, G. W., Zhou, H., He, J., Baranger, D. A. A., Gudbjartsson, D. F., Wedow, R., Adkins, D. E., Adkins, A. E., Alexander, J. & 31 others, Bacanu, S. A., Bigdeli, T. B., Boden, J., Brown, S. A., Bucholz, K. K., Bybjerg-Grauholm, J., Corley, R. P., Degenhardt, L., Dick, D. M., Domingue, B. W., Fox, L., Goate, A. M., Gordon, S. D., Hack, L. M., Hancock, D. B., Hartz, S. M., Hickie, I. B., Hougaard, D. M., Krauter, K., Lind, P. A., McClintick, J. N., McQueen, M. B., Meyers, J. L., Montgomery, G. W., Mors, O., Mortensen, P. B., Nordentoft, Merete, Pearson, J. F., Peterson, R. E., Werge, Thomas & Psychiatric Genomics Consortium Substance Use Disorders Workgroup, P. G. C. S. U. D. W., 2020, In: The Lancet Psychiatry. 7, 12, p. 1032-1045 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A major role for common genetic variation in anxiety disorders

    Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O., Bo Mortensen, P. & 6 others, Nordentoft, Merete, Werge, Thomas, Nicodemus, K. K., Mattheisen, M., Breen, G. & Eley, T. C., 2020, In: Molecular Psychiatry. 25, p. 3292–3303

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

    Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. K., Adams, M. J., Clarke, T. K., McIntosh, A. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M. & 31 others, Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Hansen, C. S., Hansen, T. F., Pedersen, C. B., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Nature Communications. 11, 1, 2301.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 34394780