Thomas Werge

Thomas Werge

Clinical Professor

Member of:

  • Psychiatry


  1. Published

    Association between GLP-1 receptor gene polymorphisms with reward Learning, anhedonia, and depression diagnosis

    Eser, H. Y., Appadurai, V., Eren, C. Y., Yazici, D., Chen, C. Y., Ongur, D., Pizzagalli, D. A., Werge, Thomas & Hall, M. H., 2020, In: Acta Neuropsychiatrica. 32, 4, p. 218-225

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine

    Esserlind, A., Christensen, A. F., Le, H., Kirchmann, M., Hauge, A. W., Toyserkani, N. M., Hansen, Torben, Grarup, Niels, Werge, Thomas, Steinberg, S., Bettella, F., Stefansson, H. & Olesen, Jes, May 2013, In: European Journal of Neurology. 20, 5, p. 765-772 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample

    Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

    Fadista, J., Skotte, L., Karjalainen, J., Abner, E., Sørensen, E., Ullum, H., Werge, Thomas, Esko, T., Milani, L., Palotie, A., Daly, M., Melbye, M., Feenstra, B., Geller, F., IPSYCH Grp, I. G. & FinnGen Consortium, F. C., 2022, In: Nature Communications. 13, 11 p., 3200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study

    Fadista, J., Yakimov, V., Võsa, U., Hansen, C. S., Kasela, S., Skotte, L., Geller, F., Courraud, J., Esko, T., Kukuškina, V., Buil, A., Melbye, M., Werge, Thomas, Hougaard, D. M., Milani, L., Bybjerg-Grauholm, J., Cohen, A. S. & Feenstra, B., 2021, In: Scientific Reports. 11, 17463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

    Fan, C. C., McGrath, J. J., Appadurai, V., Buil, A., Gandal, M. J., Schork, A. J., Mortensen, P. B., Agerbo, E., Geschwind, S. A., Geschwind, D., Werge, Thomas, Thompson, W. K. & Pedersen, C. B., 2018, In: Nature Communications. 9, 7 p., 5296.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms

    Fanous, A. H., Zhou, B., Aggen, S. H., Bergen, S. E., Amdur, R. L., Duan, J., Sanders, A. R., Shi, J., Mowry, B. J., Olincy, A., Amin, F., Cloninger, C. R., Silverman, J. M., Buccola, N. G., Byerley, W. F., Black, D. W., Freedman, R., Dudbridge, F., Holmans, P. A., Ripke, S. & 8 others, Gejman, P. V., Kendler, K. S., Levinson, D. F., Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, S. P. G. A. S. (. C., Hansen, T. F., Werge, Thomas, Olsen, L. & Rasmussen, H. B., 2012, In: American Journal of Psychiatry. 169, 12, p. 1309-17 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Evaluating historical candidate genes for schizophrenia

    Farrell, M. S., Werge, Thomas, Sklar, P., Owen, M. J., Ophoff, R. A., O'Donovan, M. C., Corvin, A., Cichon, S. & Sullivan, P. F., 2015, In: Molecular Psychiatry. 20, p. 555-62 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Genomisk medicin som forbrugervare

    Folkersen, L. & Werge, Thomas, 2019, In: Ugeskrift for Laeger. 181, 5 p., V11180789.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores

    Folkersen, L., Pain, O., Ingason, A., Werge, Thomas, Lewis, C. M. & Austin, J., 2020, In: Frontiers in Genetics. 11, 578.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

    Forsingdal, A., Fejgin, K., Nielsen, V., Werge, Thomas & Nielsen, J., 2016, In: Translational Psychiatry. 6, 7, p. 1-9 9 p., e860.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Can Animal Models of Copy Number Variants That Predispose to Schizophrenia Elucidate Underlying Biology?

    Forsingdal, A., Jørgensen, T. N., Olsen, L., Werge, Thomas, Didriksen, M. & Nielsen, J., 2019, In: Biological Psychiatry. 85, 1, p. 13-24 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

    Forstner, A. J., Awasthi, S., Wolf, C., Maron, E., Erhardt, A., Czamara, D., Eriksson, E., Lavebratt, C., Allgulander, C., Friedrich, N., Becker, J., Hecker, J., Rambau, S., Conrad, R., Geiser, F., Mcmahon, F. J., Moebus, S., Hess, T., Buerfent, B. C., Hoffmann, P. & 55 others, Herms, S., Heilmann-heimbach, S., Kockum, I., Olsson, T., Alfredsson, L., Weber, H., Alpers, G. W., Arolt, V., Fehm, L., Fydrich, T., Gerlach, A. L., Hamm, A., Kircher, T., Pané-farré, C. A., Pauli, P., Rief, W., Ströhle, A., Plag, J., Lang, T., Wittchen, H., Mattheisen, M., Meier, S., Metspalu, A., Domschke, K., Reif, A., Hovatta, I., Lindefors, N., Andersson, E., Schalling, M., Mbarek, H., Milaneschi, Y., De Geus, E. J. C., Boomsma, D. I., Penninx, B. W. J. H., Thorgeirsson, T. E., Steinberg, S., Stefansson, K., Stefansson, H., Müller-myhsok, B., Hansen, Thomas Folkmann, Børglum, A. D., Werge, Thomas, Mortensen, P. B., Nordentoft, Merete, Hougaard, D. M., Hultman, C. M., Sullivan, P. F., Nöthen, M. M., Woldbye, David Paul Drucker, Mors, O., Binder, E. B., Rück, C., Ripke, S., Deckert, J. & Schumacher, J., 2021, In: Molecular Psychiatry. 26, p. 4179–4190 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci

    Foss-Skiftesvik, J., Hagen, C. M., Mathiasen, R., Adamsen, D., Bækvad-Hansen, M., Børglum, A. D., Nordentoft, Merete, Werge, Thomas, Christiansen, M., Schmiegelow, Kjeld, Juhler, Marianne, Mortensen, P. B., Hougaard, D. M. & Bybjerg-Grauholm, J., 2021, In: Child's Nervous System. 37, p. 819–830

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

    Haney, J. R., CommonMind Consortium, C. C., PsychENCODE Consortium, P. C. & iPSYCH-BROAD Working Group, I. W. G., 9 Feb 2018, In: Science. 359, 6376, p. 693-697 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

    Ganna, A., Satterstrom, F. K., Zekavat, S. M., Das, I., Kurki, M. I., Churchhouse, C., Alfoldi, J., Martin, A. R., Havulinna, A. S., Byrnes, A., Thompson, W. K., Nielsen, P. R., Karczewski, K. J., Saarentaus, E., Rivas, M. A., Gupta, N., Pietiläinen, O., Emdin, C. A., Lescai, F., Bybjerg-Grauholm, J. & 28 others, Flannick, J., GoT2D/T2D-GENES Consortium, G. C., Mercader, J. M., Udler, M., SIGMA Consortium Helmsley IBD Exome Sequencing Project, S. C. H. I. E. S. P., FinMetSeq Consortium, F. C., iPSYCH-Broad Consortium, I. C., Laakso, M., Salomaa, V., Hultman, C., Ripatti, S., Hämäläinen, E., Moilanen, J. S., Körkkö, J., Kuismin, O., Nordentoft, Merete, Hougaard, D. M., Mors, O., Werge, Thomas, Mortensen, P. B., MacArthur, D., Daly, M. J., Sullivan, P. F., Locke, A. E., Palotie, A., Børglum, A. D., Kathiresan, S. & Neale, B. M., 2018, In: American Journal of Human Genetics. 102, 6, p. 1204-1211

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Schizophrenia polygenic risk scores, urbanicity and treatment-resistant schizophrenia

    Gasse, C., Wimberley, T., Wang, Y., Mors, O., Børglum, A., Als, T. D., Werge, Thomas, Nordentoft, Merete, Hougaard, D. M. & Horsdal, H. T., 2019, In: Schizophrenia Research. 212, p. 79-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Genome-wide association study identifies four loci associated with eruption of permanent teeth

    Geller, F., Feenstra, B., Zhang, H., Shaffer, J. R., Hansen, T., Esserlind, A-L., Boyd, H. A., Nohr, E. A., Timpson, N. J., Fatemifar, G., Paternoster, L., Evans, D. M., Weyant, R. J., Levy, S. M., Lathrop, M., Smith, G. D., Murray, J. C., Olesen, J., Werge, T. M., Marazita, M. L. & 2 others, Sørensen, Thorkild I.A. & Melbye, M., 1 Sep 2011, In: P L o S Genetics. 7, 9, p. e1002275

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions

    Giovanoli, S., Werge, Thomas, Mortensen, P. B., Didriksen, M. & Meyer, U., 2019, In: Neuropsychopharmacology. 44, 4, p. 703-710 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

    Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., de Geus, E. J. C. & 31 others, Grabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Magnusson, P. K., McGuffin, P., McIntosh, A. M., Milaneschi, Y., Mors, O., Mostafavi, S., Müller-Myhsok, B., Pedersen, N. L., Penninx, B. W. J. H., Potash, J. B., Preisig, M., Ripke, S., Shi, J., Bækvad-Hansen, M., Hansen, C. S., Hansen, Thomas Folkmann, Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Biological Psychiatry. 87, 5, p. 419-430 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The population genomic legacy of the second plague pandemic

    Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, Juan, D., Gelabert, P., de-Dios, T., Fotaki, Anna Katerina, Iraeta Orbegozo, Miren, Vågene, Åshild Joanne, Denham, S. D., Christophersen, A., Stenøien, H. K., Vieira, Filipe Garrett, Liu, Shanlin, Günther, T., Kivisild, T., Moseng, O. G., Skar, B., Cheung, C., Sandoval-Velasco, Marcela, Wales, N., Schroeder, Hannes, Campos, P. F., Guðmundsdóttir, V. B., Sicheritz-Pontén, Thomas, Petersen, Bent, Halgunset, J., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, Thomas Folkmann, Werge, Thomas, Willerslev, Eske, Balloux, F., Marques-Bonet, T., Lalueza-Fox, C., Nielsen, Rasmus, Stefánsson, K., Helgason, A. & Gilbert, M Thomas P, 2022, In: Current Biology. 32, 21, p. 4743-4751.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations

    Gordon, A., Forsingdal, A., Klewe, I. V., Nielsen, J., Didriksen, M., Werge, Thomas & Geschwind, D. H., 2021, In: Molecular Psychiatry. 26, p. 1520–1534

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

    Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H. & 31 others, Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes & International Headache Genetics Consortium, I. H. G. C., Aug 2016, In: Nature Genetics. 48, 8, p. 856-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Identification of common genetic risk variants for autism spectrum disorder

    Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, A. S. D. W. G. O. T. P. G. C., Mar 2019, In: Nature Genetics. 51, 3, p. 431-444

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

    Gudbjartsson, D. F., Bjornsdottir, U. S., Halapi, E., Helgadottir, A., Sulem, P., Jonsdottir, G. M., Thorleifsson, G., Helgadottir, H., Steinthorsdottir, V., Stefansson, H., Williams, C., Hui, J., Beilby, J., Warrington, N. M., James, A., Palmer, L. J., Koppelman, G. H., Heinzmann, A., Krueger, M., Boezen, H. M. & 126 others, Wheatley, A., Altmuller, J., Shin, H. D., Uh, S., Cheong, H. S., Jonsdottir, B., Gislason, D., Park, C., Rasmussen, L. M., Porsbjerg, Celeste Michala, Hansen, J. W., Backer, Vibeke, Werge, Thomas, Janson, C., Jönsson, U., Ng, M. C. Y., Chan, J., So, W. Y., Ma, R., Shah, S. H., Granger, C. B., Quyyumi, A. A., Levey, A. I., Vaccarino, V., Reilly, M. P., Rader, D. J., Williams, M. J. A., van Rij, A. M., Jones, G. T., Trabetti, E., Malerba, G., Pignatti, P. F., Boner, A., Pescollderungg, L., Girelli, D., Olivieri, O., Martinelli, N., Ludviksson, B. R., Ludviksdottir, D., Eyjolfsson, G. I., Arnar, D., Thorgeirsson, G., Deichmann, K., Thompson, P. J., Wjst, M., Hall, I. P., Postma, D. S., Gislason, T., Gulcher, J., Kong, A., Jonsdottir, I., Thorsteinsdottir, U., Stefansson, K., Gudbjartsson, D. F., Bjornsdottir, U. S., Halapi, E., Helgadottir, A., Sulem, P., Jonsdottir, G. M., Thorleifsson, G., Helgadottir, H., Steinthorsdottir, V., Stefansson, H., Williams, C., Hui, J., Beilby, J., Warrington, N. M., James, A., Palmer, L. J., Koppelman, G. H., Heinzmann, A., Krueger, M., Boezen, H. M., Wheatley, A., Altmuller, J., Shin, H. D., Uh, S., Cheong, H. S., Jonsdottir, B., Gislason, D., Park, C., Rasmussen, L. M., Porsbjerg, C. M., Hansen, J. W., Backer, Vibeke, Werge, Thomas, Janson, C., Jönsson, U., Ng, M. C. Y., Chan, J., So, W. Y., Ma, R., Shah, S. H., Granger, C. B., Quyyumi, A. A., Levey, A. I., Vaccarino, V., Reilly, M. P., Rader, D. J., Williams, M. J. A., van Rij, A. M., Jones, G. T., Trabetti, E., Malerba, G., Pignatti, P. F., Boner, A., Pescollderungg, L., Girelli, D., Olivieri, O., Martinelli, N., Ludviksson, B. R., Ludviksdottir, D., Eyjolfsson, G. I., Arnar, D., Thorgeirsson, G., Deichmann, K., Thompson, P. J., Wjst, M., Hall, I. P., Postma, D. S., Gislason, T., Gulcher, J., Kong, A., Jonsdottir, I., Thorsteinsdottir, U. & Stefansson, K., 2009, In: Nature Genetics. 41, 3, p. 342-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 34394780