Thomas Werge
Clinical Professor
- 2019
- Published
GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C. B. D. W. G. O. T. P. G. C. S. W. G. O. T. P. G. C., Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C. M., 2019, In: American Journal of Psychiatry. 176, 8, p. 651-660Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardiñas, A. F., Rajagopal, V. M., Als, T. D., T. Nguyen, H., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Domenici, E., Gamazon, E. R., Purcell, S., CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, iPSYCH-GEMS Schizophrenia Working Group & 15 others, , 2019, In: Nature Genetics. 51, p. 659-674Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variants Associated with Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study
Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., Bækved-Hansen, M., Sokolowska, E., Mortensen, P. B., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Breen, G., Børglum, A. D., Eley, T. C., Hovatta, I., Mattheisen, M. & Mors, O., 2019, In: JAMA Psychiatry. 76, 9, p. 924-932 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study implicates CHRNA2 in cannabis use disorder
Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., Gudbjartsson, D. F., Pallesen, J., Hjorthøj, C., Reginsson, G. W., Tyrfingsson, T., Runarsdottir, V., Qvist, P., Christensen, J. H., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Huckins, L. M., Stahl, E. A., Timmermann, A., Agerbo, E. & 10 others, , 2019, In: Nature Neuroscience. 22, 7, p. 1066-1074Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Cell. 179, 7, p. 1469-1482 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomisk medicin som forbrugervare
Folkersen, L. & Werge, Thomas, 2019, In: Ugeskrift for Laeger. 181, 5 p., V11180789.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Disease Variation in the Light of Population Genomics
Prohaska, Ana, Racimo, Fernando, Schork, A. J., Sikora, Martin, Stern, A. J., Ilardo, M., Allentoft, Morten Erik, Folkersen, L., Buil, A., Moreno Mayar, J. Víctor, Korneliussen, Thorfinn Sand, Geschwind, D., Ingason, A., Werge, Thomas, Nielsen, Rasmus & Willerslev, Eske, 2019, In: Cell. 177, 1, p. 115-131 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders
Nudel, R., Benros, Michael Eriksen, Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Nordentoft, Merete, Mors, O., Hougaard, D. M., Mortensen, P. B., Buil, A., Werge, Thomas, Rasmussen, Simon & Thompson, W. K., 2019, In: European Journal of Human Genetics. 27, p. 1445-1455Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individuals with 22q11.2 deletion syndrome show intact prediction but reduced adaptation in responses to repeated sounds: Evidence from Bayesian mapping
Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Olsen, L., Didriksen, M., Baaré, W. F. C., Werge, Thomas, Garrido, M. I. & Siebner, Hartwig Roman, 2019, In: NeuroImage: Clinical. 22, 101721.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Nature Communications. 10, 1, 18 p., 2548.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions
Giovanoli, S., Werge, Thomas, Mortensen, P. B., Didriksen, M. & Meyer, U., 2019, In: Neuropsychopharmacology. 44, 4, p. 703-710 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C-Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M., Amstadter, A. B. & 159 others, , 2019, In: Nature Communications. 10, 1, 4558.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, K., Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, D., Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, S., Pedersen, C. B., Fuller Torrey, E., Werge, T., Bo Mortensen, P. & 2 others, , 2019, In: Brain, Behavior, and Immunity. 79, p. 152-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Migraine polygenic risk score associates with efficacy of migraine-specific drugs
Kogelman, L. J. A., Esserlind, A-L., Christensen, A. F., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B., Erikstrup, C., Hjalgrim, H., Ullum, H., Olesen, J., Hansen, T. F., Gudbjartsson, D., Gastafsson, O., Stefansson, K., Stefansson, H., Porsteinsdottir, U., Andersen, S., Banasik, K., Brunak, S. & 73 others, , 2019, In: Neurology: Genetics. 5, 6, 12 p., e364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A. & 32 others, , 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations
Wang, Y., Karstoft, Karen-Inge, Nievergelt, C. M., Maihofer, A. X., Stein, M. B., Ursano, R. J., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Andreassen, O. A., Werge, Thomas, Thompson, W. K. & Andersen, S. B., 2019, In: Journal of Affective Disorders. 252, p. 350-357 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders
Skogstrand, K., Hagen, C. M., Borbye-Lorenzen, N., Christiansen, M., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Werge, Thomas, Borglum, A., Mors, O., Nordentoft, M., Mortensen, P. B. & Hougaard, D. M., 2019, In: Translational Psychiatry. 9, 9 p., 252.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roadmap for a precision-medicine initiative in the Nordic region
Njølstad, P. R., Andreassen, O. A., Brunak, S., Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A., Mortensen, P. B., Palmgren, J. & 11 others, , 2019, In: Nature Genetics. 51, p. 924-930Research output: Contribution to journal › Comment/debate › Research
- Published
Schizophrenia polygenic risk scores, urbanicity and treatment-resistant schizophrenia
Gasse, C., Wimberley, T., Wang, Y., Mors, O., Børglum, A., Als, T. D., Werge, Thomas, Nordentoft, Merete, Hougaard, D. M. & Horsdal, H. T., 2019, In: Schizophrenia Research. 212, p. 79-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes
Bybjerg-Grauholm, J., Hagen, C. M., Gonçalves, V. F., Bækvad-Hansen, M., Hansen, C. S., Hedley, P. L., Kanters, Jørgen K., Nielsen, J., Theisen, M., Mors, O., Kennedy, J., Als, T. D., Demur, A. B., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 13 Dec 2018, In: PLoS ONE. 13, 12, 26 p., e0208829.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease
Hagen, C. M., Gonçalves, V. F., Hedley, P. L., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., Kanters, Jørgen K., Nielsen, J., Mors, O., Demur, A. B., Als, T. D., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Kennedy, J., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 1 Dec 2018, In: PLoS ONE. 13, 12, 14 p., e0208828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk
International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu, I. M. S. G. C. E. A. C. C. E., Sellebjerg, Finn Thorup, Ullum, H. & Werge, Thomas, 29 Nov 2018, In: Cell. 175, 6, p. 1679-1687.e7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Socio-demographic characteristics of adults with self-reported ADHD symptoms in a Danishpopulation of 12,415 blood donors
Høffding, L. K. E., Nielsen, Maria Haahr, Didriksen, Maria, Schow, T., Werge, Thomas, Nielsen, K. R., Erikstrup, C., Pedersen, O. B., Hjalgrim, H., Jepsen, J. R. M., Hansen, T. F., Banasik, K., Ullum, H. & Burgdorf, K., 20 Aug 2018, In: Journal of Psychiatry and Behavioral Sciences. 3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder
Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., Brikell, I., Ghirardi, L., Larsson, H., Lichtenstein, P., Eriksson, N., 23andMe Research Team, 2. R. T., Psychiatric Genomics Consortium: ADHD Subgroup, P. G. C. A. S., iPSYCH–Broad ADHD Workgroup, I. A. W., Werge, Thomas & Nordentoft, Merete, 15 Jun 2018, In: Biological Psychiatry. 83, 12, p. 1044-1053 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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588
downloads
Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
340
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
Published