Considerable haplotype diversity within the 23kb encompassing the ADH7 gene

Research output: Contribution to journalJournal articleResearchpeer-review

  • Yi Han
  • Hiroki Oota
  • Michael V Osier
  • Andrew J Pakstis
  • William C Speed
  • Adekunle Odunsi
  • Friday Okonofua
  • Sylvester L B Kajuna
  • Nganyirwa J Karoma
  • Selemani Kungulilo
  • Elena Grigorenko
  • Olga V Zhukova
  • Batsheva Bonne-Tamir
  • Ru-B Lu
  • Parnas, Josef
  • Leslie O Schulz
  • Judith R Kidd
  • Kenneth K Kidd
Of the seven known human alcohol dehydrogenase (ADH) genes, the non-liver expressed ADH7 gene codes for the enzyme with the highest maximal activity for ethanol. Previous study from our laboratory has suggested that ADH7 has an epistatic role for protection against alcoholism based on a single ADH7 SNP.
Original languageEnglish
JournalAlcoholism: Clinical and Experimental Research
Volume29
Issue number12
Pages (from-to)2091-100
Number of pages10
ISSN0145-6008
Publication statusPublished - 2005

ID: 87041