Data-Driven Learning in High-Resolution Activity Sampling From Patients With Bipolar Depression: Mixed-Methods Study
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Data-Driven Learning in High-Resolution Activity Sampling From Patients With Bipolar Depression : Mixed-Methods Study. / Rohani, Darius Adam; Tuxen, Nanna; Quemada Lopategui, Andrea; Kessing, Lars Vedel; Bardram, Jakob Eyvind.
In: J M I R Mental Health, Vol. 5, No. 2, e10122, 2018, p. 1-12.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Data-Driven Learning in High-Resolution Activity Sampling From Patients With Bipolar Depression
T2 - Mixed-Methods Study
AU - Rohani, Darius Adam
AU - Tuxen, Nanna
AU - Quemada Lopategui, Andrea
AU - Kessing, Lars Vedel
AU - Bardram, Jakob Eyvind
PY - 2018
Y1 - 2018
N2 - BACKGROUND: Behavioral activation is a pen and paper-based therapy form for treating depression. The patient registers their activity hourly, and together with the therapist, they agree on a plan to change behavior. However, with the limited clinical personnel, and a growing patient population, new methods are needed to advance behavioral activation.OBJECTIVE: The objectives of this paper were to (1) automatically identify behavioral patterns through statistical analysis of the paper-based activity diaries, and (2) determine whether it is feasible to move the behavioral activation therapy format to a digital solution.METHODS: We collected activity diaries from seven patients with bipolar depression, covering in total 2,480 hours of self-reported activities. A pleasure score, on a 1-10 rating scale, was reported for each activity. The activities were digitalized into 6 activity categories, and statistical analyses were conducted.RESULTS: Across all patients, movement-related activities were associated with the highest pleasure score followed by social activities. On an individual level, through a nonparametric Wilcoxon Signed-Rank test, one patient had a statistically significant larger amount of spare time activities when feeling bad (z=-2.045, P=.041). Through a within-subject analysis of covariance, the patients were found to have a better day than the previous, if that previous day followed their diurnal rhythm (ρ=.265, P=.029). Furthermore, a second-order trend indicated that two hours of daily social activity was optimal for the patients (β2=-0.08, t (63)=-1.22, P=.23).CONCLUSIONS: The data-driven statistical approach was able to find patterns within the behavioral traits that could assist the therapist in as well as help design future technologies for behavioral activation.
AB - BACKGROUND: Behavioral activation is a pen and paper-based therapy form for treating depression. The patient registers their activity hourly, and together with the therapist, they agree on a plan to change behavior. However, with the limited clinical personnel, and a growing patient population, new methods are needed to advance behavioral activation.OBJECTIVE: The objectives of this paper were to (1) automatically identify behavioral patterns through statistical analysis of the paper-based activity diaries, and (2) determine whether it is feasible to move the behavioral activation therapy format to a digital solution.METHODS: We collected activity diaries from seven patients with bipolar depression, covering in total 2,480 hours of self-reported activities. A pleasure score, on a 1-10 rating scale, was reported for each activity. The activities were digitalized into 6 activity categories, and statistical analyses were conducted.RESULTS: Across all patients, movement-related activities were associated with the highest pleasure score followed by social activities. On an individual level, through a nonparametric Wilcoxon Signed-Rank test, one patient had a statistically significant larger amount of spare time activities when feeling bad (z=-2.045, P=.041). Through a within-subject analysis of covariance, the patients were found to have a better day than the previous, if that previous day followed their diurnal rhythm (ρ=.265, P=.029). Furthermore, a second-order trend indicated that two hours of daily social activity was optimal for the patients (β2=-0.08, t (63)=-1.22, P=.23).CONCLUSIONS: The data-driven statistical approach was able to find patterns within the behavioral traits that could assist the therapist in as well as help design future technologies for behavioral activation.
U2 - 10.2196/10122
DO - 10.2196/10122
M3 - Journal article
C2 - 29954726
VL - 5
SP - 1
EP - 12
JO - J M I R Mental Health
JF - J M I R Mental Health
SN - 2368-7959
IS - 2
M1 - e10122
ER -
ID: 215922485