Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events
Research output: Contribution to journal › Journal article › Research › peer-review
Depression is accompanied by an inflammatory reaction and activation of cell mediated immunity (CMI) and stressors may induce the cytokine network in humans. The proinflammatory cytokine interleukin-18 (IL-18) is less investigated in depression but highly relevant since it is produced by activated macrophages and expressed in the brain.
| Original language | English |
|---|---|
| Journal | Journal of Affective Disorders |
| Volume | 136 |
| Issue number | 1-2 |
| Pages (from-to) | 134-138 |
| Number of pages | 5 |
| ISSN | 0165-0327 |
| DOIs | |
| Publication status | Published - 2012 |
ID: 36143450