Interpretation of composite endpoints in urology: an analysis of citation quality

Research output: Contribution to journalJournal articleResearchpeer-review

Objective: To investigate how urological studies using composite endpoints as the primary outcome were cited. Materials and methods: In this quality analysis of citations, three randomized clinical trials each investigating oncological and non-oncological urology were selected for citation analysis based on pre-defined criteria. In total, 531 papers citing the selected studies were reviewed; citations were evaluated based on whether they correctly referred to the composite endpoint and if singleton endpoints were defined and/or discussed. Results: Among the citations, 223/531 (42%) referred to the composite endpoint, of which 217/223 (97.3%) correctly cited the composite endpoint. However, only 91/217 (41.9%) defined and/or discussed the singleton endpoints of the composite endpoint. The lack of a validated instrument for citation analysis was a limitation of this study. Meanwhile, the main strength is the large number of individually analyzed citations. Conclusions: The composite endpoints of urological randomized clinical trials are generally cited without referring to the composite endpoint; when cited, the composite endpoints are described correctly. However, in most cases, without defining or discussing the singleton endpoints.

Original languageEnglish
JournalScandinavian Journal of Urology
Volume56
Issue number3
Pages (from-to)206-212
Number of pages7
ISSN2168-1805
DOIs
Publication statusPublished - 2022

Bibliographical note

Publisher Copyright:
© 2022 Acta Chirurgica Scandinavica Society.

    Research areas

  • citations, composite endpoints, endpoints, Randomized controlled trials, urology

ID: 313651118