Ulrik Niels Lassen

Ulrik Niels Lassen

Clinical Professor

Member of:

  • Clinical Oncology


  1. Published

    First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors

    Abdul Razak, A. R., Mau-Sørensen, M., Gabrail, N. Y., Gerecitano, J. F., Shields, A. F., Unger, T. J., Saint-Martin, J. R., Carlson, R., Landesman, Y., McCauley, D., Rashal, T., Lassen, Ulrik Niels, Kim, R., Stayner, L., Mirza, M. R., Kauffman, M., Shacham, S. & Mahipal, A., Dec 2016, In: Journal of Clinical Oncology. 34, 34, p. 4142-4150 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Application of cell-free DNA for genomic tumor profiling: a feasibility study

    Ahlborn, L. B., Rohrberg, K. S., Gabrielaite, M., Tuxen, I. V., Yde, C. W., Spanggaard, I., Santoni Rugiu, Eric, Nielsen, Finn Cilius, Lassen, Ulrik Niels, Mau-Sorensen, M. & Østrup, O., Feb 2019, In: OncoTarget. 10, 14, p. 1388-1398

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Concordance of mutation detection in circulating tumor DNA in early clinical trials using different blood collection protocols

    Ahlborn, L. B., Madsen, M., Jonson, L., Nielsen, Finn Cilius, Lassen, Ulrik Niels, Yde, C. W. & Mau-Sorensen, M., 2017, In: Clinical Laboratory. 63, 10, p. 1755-1759

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors

    Ahlborn, L. B., Tuxen, I. V., Mouliere, F., Kinalis, S., Schmidt, A. Y., Rohrberg, K. S., Santoni Rugiu, Eric, Nielsen, Finn Cilius, Lassen, Ulrik Niels, Yde, C. W., Oestrup, O. & Mau-Sorensen, M., 2018, In: OncoTarget. 9, 66, p. 32570-32579

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The effect of bevacizumab on vestibular schwannoma tumour size and hearing in patients with neurofibromatosis type 2

    Alanin, M. C., Klausen, C., Cayé-Thomasen, Per, Thomsen, C., Fugleholm, K., Poulsgaard, L., Lassen, Ulrik Niels, Mau-Sorensen, M. & Hofland, K. F., Dec 2015, In: European Archives of Oto-Rhino-Laryngology. 272, 12, p. 3627-3633 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Effect of bevacizumab on intracranial meningiomas in patients with neurofibromatosis type 2: a retrospective case series

    Alanin, M. C., Klausen, C., Cayé-Thomasen, Per, Thomsen, C., Fugleholm, Kåre, Poulsgaard, L., Lassen, Ulrik Niels, Mau-Sørensen, M. & Hofland, K. F., 2016, In: International Journal of Neuroscience. 126, 11, p. 1002-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A prospective PET study of patients with glioblastoma multiforme

    Andersen, P. B., Blinkenberg, M., Lassen, Ulrik Niels, Kosteljanetz, M., Wagner, A., Poulsen, H. S., Sørensen, Per Soelberg & Paulson, Olaf B., Jun 2006, In: Acta Neurologica Scandinavica. 113, 6, p. 412-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome

    Araujo B de Lima, V., Borch, A., Hansen, M., Draghi, A., Spanggaard, I., Rohrberg, K., Reker Hadrup, S., Lassen, Ulrik Niels & Svane, Inge Marie, Apr 2020, In: Cytotherapy. 22, 4, p. 204-213 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types

    Araujo B. de Lima, V., Hansen, M., Spanggaard, I., Rohrberg, K., Reker Hadrup, S., Lassen, Ulrik Niels & Svane, Inge Marie, 25 Mar 2021, In: Frontiers in Oncology. 11, 11 p., 558248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein

    Bang-Christensen, S. R., Pedersen, R. S., Pereira, M. A., Clausen, T. M., Løppke, C., Sand, N. T., Ahrens, T. D., Jørgensen, A. M., Lim, Y. C., Goksøyr, L., Choudhary, S., Gustavsson, T., Dagil, R., Daugaard, M., Sander, A. F., Torp, M. H., Søgaard, M., Theander, T. G., Østrup, O., Lassen, U. & 3 others, Hamerlik, P., Salanti, Ali & Agerbæk, Mette Ørskov, 2019, In: Cells. 8, 9, 21 p., 998.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    New pathogenic germline variants identified in mesothelioma

    Belcaid, L., Bertelsen, B., Wadt, Karin Anna Wallentin, Tuxen, I., Spanggaard, I., Højgaard, M., Sørensen, Jens Benn, Ravn, J., Lassen, Ulrik Niels, Nielsen, Finn Cilius, Rohrberg, K. & Westmose Yde, C., 2023, In: Lung Cancer. 179, 8 p., 107172.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    High frequency of pathogenic germline variants within homologous recombination repair in patients with advanced cancer

    Bertelsen, B., Tuxen, I. V., Yde, C. W., Gabrielaite, M., Torp, M. H., Kinalis, S., Oestrup, O., Rohrberg, K., Spangaard, I., Santoni Rugiu, Eric, Wadt, Karin Anna Wallentin, Mau-Sorensen, M., Lassen, Ulrik Niels & Nielsen, Finn Cilius, 2019, In: npj Genomic Medicine. 4, 1, 11 p., 13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Putting data to work for precision medicine

    Bjerrum, A. & Lassen, Ulrik Niels, 2023, In: Cell Reports Medicine. 4, 7, 3 p., 101090.

    Research output: Contribution to journalComment/debateResearchpeer-review

  14. Published

    Phase I/IIa, open-label, multicentre study to evaluate the optimal dosing and safety of ODM-203 in patients with advanced or metastatic solid tumours

    Bono, P., Massard, C., Peltola, K. J., Azaro, A., Italiano, A., Kristeleit, R. S., Curigliano, G., Lassen, Ulrik Niels, Arkenau, H. T., Hakulinen, P., Garratt, C., Ikonen, T., Mustonen, M. V. J. & Rodon, J. A., 2020, In: ESMO Open. 5, 6, 11 p., e001081.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

    Borch, A., Bjerregaard, A. M., Araujo Barbosa de Lima, V., Østrup, O., Yde, C. W., Eklund, A. C., Mau-Sørensen, M., Barra, C., Svane, Inge Marie, Nielsen, Finn Cilius, Funt, S. A., Lassen, Ulrik Niels & Hadrup, S. R., 2023, In: Frontiers in Genetics. 14, 13 p., 1058605.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Phase I dose escalation, pharmacokinetic and pharmacodynamic study of naptumomab estafenatox alone in patients with advanced cancer and with docetaxel in patients with advanced non-small-cell lung cancer

    Borghaei, H., Alpaugh, K., Hedlund, G., Forsberg, G., Langer, C., Rogatko, A., Hawkins, R., Dueland, S., Lassen, Ulrik Niels & Cohen, R. B., 2009, In: Journal of Clinical Oncology. 27, 25, p. 4116-23 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Estimating Long-Term Survival Outcomes for Tumor-Agnostic Therapies: Larotrectinib Case Study

    Briggs, A., Paracha, N., Rosettie, K., Upton, A., Bokemeyer, C., Lassen, Ulrik Niels & Sullivan, S. D., Jan 2022, In: Oncology. 100, 2, p. 124–129 6 p.

    Research output: Contribution to journalLetterResearchpeer-review

  18. Published

    Changes in key recruitment performance metrics from 2008-2019 in industrysponsored phase III clinical trials registered at ClinicalTrials.gov

    Brøgger-Mikkelsen, Mette, Zibert, J. R., Andersen, A. D., Lassen, Ulrik Niels, Hædersdal, Merete, Ali, Z. & Thomsen, Simon Francis, 2022, In: PLoS ONE. 17, 7 July, p. 1-15 e0271819.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Comparative Effectiveness of Larotrectinib and Entrectinib for TRK Fusion Cancer

    Carlson, J. J., Italiano, A., Brose, M. S., Federman, N., Lassen, Ulrik Niels, Kummar, S. & Sullivan, S. D., 2022, In: American Journal of Managed Care. 28, p. S26-S32

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A phase Ib/II study of HER3-targeting lumretuzumab in combination with carboplatin and paclitaxel as first-line treatment in patients with advanced or metastatic squamous non-small cell lung cancer

    Cejalvo, J. M., Jacob, W., Fleitas Kanonnikoff, T., Felip, E., Navarro Mendivil, A., Martinez Garcia, M., Taus Garcia, A., Leighl, N., Lassen, Ulrik Niels, Mau-Soerensen, M., Adessi, C., Michielin, F., James, I., Ceppi, M., Hasmann, M., Weisser, M. & Cervantes, A., 2019, In: ESMO Open. 4, 4, 7 p., e000532.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The role of nuclear medicine in the diagnosis of cancer of unknown origin

    Demir, H., Berk, F., Raderer, M., Plowman, P. N., Lassen, Ulrik Niels, Daugaard, G., Clausen, M., Bohuslavizki, K. H., Peters, M., Harmer, C., Malamitsi, J. & Aktolun, C., Jun 2004, In: American Journal of Nuclear Medicine and Molecular Imaging. 48, 2, p. 164-73 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    First-in-Man Dose-Escalation Study of the Selective BRAF Inhibitor RG7256 in Patients with BRAF V600-Mutated Advanced Solid Tumors

    Dienstmann, R., Lassen, Ulrik Niels, Cebon, J., Desai, J., Brown, M. P., Evers, S., Su, F., Zhang, W., Boisserie, F., Lestini, B., Schostack, K., Meresse, V. & Tabernero, J., Apr 2016, In: Targeted Oncology. 11, 2, p. 149-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Phase II activity of belinostat (PXD-101), carboplatin, and paclitaxel in women with previously treated ovarian cancer

    Dizon, D. S., Damstrup, L., Finkler, N. J., Lassen, Ulrik Niels, Celano, P., Glasspool, R., Crowley, E., Lichenstein, H. S., Knoblach, P. & Penson, R. T., Jul 2012, In: International Journal of Gynecological Cancer. 22, 6, p. 979-86 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    Clinical trial allocation in multinational pharmaceutical companies: a qualitative study on influential factors

    Dombernowsky, T., Hædersdal, Merete, Lassen, Ulrik Niels & Thomsen, Simon Francis, Jun 2017, In: Pharmacology Research & Perspectives. 5, 3, 9 p., e00317.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Development in the number of clinical trial applications in Western Europe from 2007 to 2015: retrospective study of data from national competent authorities

    Dombernowsky, T., Hædersdal, Merete, Lassen, Ulrik Niels & Thomsen, Simon Francis, Jul 2017, In: B M J Open. 7, 7, 10 p., e015579.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase Fusion–Positive Lung Cancers

    Drilon, A., Tan, D. S. W., Lassen, Ulrik Niels, Leyvraz, S., Liu, Y., Patel, J. D., Rosen, L., Solomon, B., Norenberg, R., Dima, L., Brega, N., Shen, L., Moreno, V., Kummar, S. & Lin, J. J., 2022, In: JCO Precision Oncology. 6, 10 p., e2100418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children

    Drilon, A., Laetsch, T. W., Kummar, S., DuBois, S. G., Lassen, U. N., Demetri, G. D., Nathenson, M., Doebele, R. C., Farago, A. F., Pappo, A. S., Turpin, B., Dowlati, A., Brose, M. S., Mascarenhas, L., Federman, N., Berlin, J., El-Deiry, W. S., Baik, C., Deeken, J., Boni, V. & 18 others, Nagasubramanian, R., Taylor, M., Rudzinski, E. R., Meric-Bernstam, F., Sohal, D. P. S., Ma, P. C., Raez, L. E., Hechtman, J. F., Benayed, R., Ladanyi, M., Tuch, B. B., Ebata, K., Cruickshank, S., Ku, N. C., Cox, M. C., Hawkins, D. S., Hong, D. S. & Hyman, D. M., 2018, In: The New England Journal of Medicine. 378, 8, p. 731-739

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Precision cancer medicine: Concepts, current practice, and future developments

    Edsjö, A., Holmquist, L., Geoerger, B., Nowak, F., Gomon, G., Alix-Panabières, C., Ploeger, C., Lassen, Ulrik Niels, Le Tourneau, C., Lehtiö, J., Ott, P. A., von Deimling, A., Fröhling, S., Voest, E., Klauschen, F., Dienstmann, R., Alshibany, A., Siu, L. L. & Stenzinger, A., 2023, In: Journal of Internal Medicine. 294, 4, p. 455-481 27 p.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    TP53 mutations are frequently concurrent in patients with BRAF V600E mutated solid tumors and is associated with shorter duration of response to BRAF targeted therapy

    Eriksen, M., Yde, C. W., Ahlborn, L. B., Qvortrup, Camilla, Lassen, Ulrik Niels, Højgaard, M., Spanggaard, I. & Rohrberg, K. S., 2022, In: European Journal of Cancer. 174, S1, p. S118

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Safety and clinical activity of the Notch inhibitor, crenigacestat (LY3039478), in an open-label phase I trial expansion cohort of advanced or metastatic adenoid cystic carcinoma

    Even, C., Lassen, Ulrik Niels, Merchan, J., Le Tourneau, C., Soria, J. C., Ferte, C., Ricci, F., Diener, J. T., Yuen, E., Smith, C., Oakley, G. J., Benhadji, K. A. & Massard, C., Apr 2020, In: Investigational New Drugs. 38, 2, p. 402-409

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    A prospective study of PET/CT in initial staging of small-cell lung cancer: comparison with CT, bone scintigraphy and bone marrow analysis

    Fischer, Barbara Malene Bjerregaard, Mortensen, J., Langer, Seppo W., Loft, A., Berthelsen, A. K., Petersen, B. I., Daugaard, G., Lassen, Ulrik Niels & Hansen, H. H., Feb 2007, In: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 18, 2, p. 338-45 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    PET in staging of patients with small cell lung cancer - preliminary results

    Fischer, Barbara Malene Bjerregaard, Mortensen, Jann, Langer, Seppo W., Eigtved, A., Berthelsen, A., Lassen, Ulrik Niels, Daugaard, G. & Hansen, H., Aug 2004, In: European Journal of Nuclear Medicine and Molecular Imaging. 31, p. S352-S352 1 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  34. Published

    Preoperative staging of lung cancer with combined PET-CT

    Fischer, B., Lassen, U., Mortensen, J., Larsen, S., Loft, A., Bertelsen, A., Ravn, J., Clementsen, P., Høgholm, A., Larsen, K., Rasmussen, T., Keiding, S., Dirksen, A., Gerke, O., Skov, B., Steffensen, I., Hansen, H., Vilmann, P., Jacobsen, G., Backer, V. & 5 others, Maltbaek, N., Pedersen, J., Madsen, H., Nielsen, H. & Højgaard, Liselotte, 2009, In: New England Journal of Medicine. 361, 1, p. 32-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Multimodality approach to mediastinal staging in non-small cell lung cancer. Faults and benefits of PET-CT: a randomised trial

    Fischer, B. M., Mortensen, Jann, Hansen, H., Vilmann, Peter, Larsen, S., Loft, A., Bertelsen, A., Ravn, J., Clementsen, P., Høegholm, A., Larsen, K. R., Dirksen, A., Skov, B. G., Krasnik, M., Højgaard, Liselotte, Lassen, Ulrik Niels, Larsen, S. S., Jakobsen, A. L. & Berthelsen, A. K., 1 Apr 2011, In: Thorax. 66, 4, p. 294-300 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    PET/CT imaging in response evaluation of patients with small cell lung cancer

    Fischer, Barbara Malene Bjerregaard, Mortensen, Jann, Langer, Seppo W., Loft, A., Berthelsen, A. K., Daugaard, G., Lassen, Ulrik Niels & Hansen, H. H., Oct 2006, In: Lung Cancer. 54, 1, p. 41-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    PET-CT in preoperative staging of lung cancer

    Fischer, Barbara Malene Bjerregaard, Lassen, Ulrik Niels & Højgaard, Liselotte, 10 Mar 2011, In: New England Journal of Medicine. 364, 10, p. 980-1 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Implementing targeted therapies in the treatment of glioblastoma: Previous shortcomings, future promises, and a multimodal strategy recommendation

    Fougner, V., Hasselbalch, B., Lassen, Ulrik Niels, Weischenfeldt, Joachim Lütken, Poulsen, H. S. & Urup, T., 2022, In: Neuro-Oncology Advances. 4, 1, vdac157.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Distress and perceived information among patients in phase I trials and their relatives: A prospective study

    Gad, K. T., Dalton, Susanne Oksbjerg, Envold, P. B., Duun-henriksen, A. K., Lassen, Ulrik Niels, Mau-sørensen, M., Rohrberg, K. S., Spanggaard, I., Von Heymann, A., Høeg, B. L. & Johansen, Christoffer, 1 Sep 2020, In: Annals of Oncology. 31, p. S497 1 p., 591P .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Patients in phase 1 cancer trials: psychological distress and understanding of trial information

    Gad, K. T., Lassen, Ulrik Niels, Duun-Henriksen, A. K., Dalton, Susanne Oksbjerg, Mau-Sørensen, M., Bidstrup, P. E., Høeg, B. L., Rohrberg, K. S., Spanggard, I., von Heymann, A. & Johansen, Christoffer, 2022, In: Acta Oncologica. 61, 3, p. 341-348 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Patient information in phase 1 trials: A systematic review

    Gad, K. T., Lassen, Ulrik Niels, Mau-Søerensen, M., Høybye, M. T. & Johansen, Christoffer, Mar 2018, In: Psycho-Oncology. 27, 3, p. 768-780

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Socioeconomic Differences in Referral to Phase I Cancer Clinical Trials: A Danish Matched Cancer Case-Control Study

    Gad, K. T., Johansen, Christoffer, Duun-Henriksen, A. K., Krøyer, A., Olsen, M. H., Lassen, Ulrik Niels, Mau-Sørensen, M. & Dalton, Susanne Oksbjerg, 1 May 2019, In: Journal of Clinical Oncology. 37, 13, p. 1111-1119

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Indirect Treatment Comparison of Larotrectinib versus Entrectinib in Treating Patients with TRK Gene Fusion Cancers

    Garcia‐foncillas, J., Bokemeyer, C., Italiano, A., Keating, K., Paracha, N., Fellous, M., Marian, M., Fillbrunn, M., Gao, W., Ayyagari, R. & Lassen, Ulrik Niels, 2022, In: Cancers. 14, 7, 15 p., 1793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Decline in CA19-9 during chemotherapy predicts survival in four independent cohorts of patients with inoperable bile duct cancer

    Grunnet, M., Christensen, I. J., Lassen, Ulrik Niels, Jensen, L. H., Lydolph, M., Knox, J. J., McNamara, M. G., Jitlal, M., Wasan, H., Bridgewater, J., Valle, J. W. & Mau-Sørensen, M., Jul 2015, In: European journal of cancer (Oxford, England : 1990). 51, 11, p. 1381-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Phase 1 study of the immunotoxin LMB-100 in patients with mesothelioma and other solid tumors expressing mesothelin

    Hassan, R., Alewine, C., Mian, I., Spreafico, A., Siu, L. L., Gomez-Roca, C., Delord, J. P., Italiano, A., Lassen, Ulrik Niels, Soria, J. C., Bahleda, R., Thomas, A., Steinberg, S. M., Peer, C. J., Figg, W. D., Niederfellner, G., Méresse Naegelen, V. & Pastan, I., 2020, In: Cancer. 126, 22, p. 4936-4947 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial

    Hasselbalch, B., Lassen, Ulrik Niels, Hansen, S., Holmberg, M., Sørensen, M., Kosteljanetz, M., Broholm, H., Stockhausen, M. & Poulsen, H. S., May 2010, In: Neuro-Oncology. 12, 5, p. 508-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Prospective evaluation of angiogenic, hypoxic and EGFR-related biomarkers in recurrent glioblastoma multiforme treated with cetuximab, bevacizumab and irinotecan

    Hasselbalch, B., Eriksen, J. G., Broholm, H., Christensen, I. J., Grunnet, K., Horsman, M. R., Poulsen, H. S., Stockhausen, M. & Lassen, Ulrik Niels, Aug 2010, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 118, 8, p. 585-94 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial

    Hasselbalch, B., Lassen, Ulrik Niels, Hansen, S., Holmberg, M., Sørensen, M., Kosteljanetz, M., Broholm, H., Stockhausen, M. & Poulsen, H. S., 1 May 2010, In: Neuro-Oncology. 12, 5, p. 508-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Cetuximab insufficiently inhibits glioma cell growth due to persistent EGFR downstream signaling

    Hasselbalch, B., Lassen, Ulrik Niels, Poulsen, H. S. & Stockhausen, M., 1 Oct 2010, In: Cancer Investigation. 28, 8, p. 775-87 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Prospective evaluation of angiogenic, hypoxic and EGFR-related biomarkers in recurrent glioblastoma multiforme treated with cetuximab, bevacizumab and irinotecan

    Hasselbalch, B., Eriksen, J. G., Broholm, H., Christensen, I. J., Grunnet, K., Horsman, M. R., Poulsen, H. S., Stockhausen, M. & Lassen, Ulrik Niels, 1 Aug 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 8, p. 585-94 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Actively personalized vaccination trial for newly diagnosed glioblastoma

    Hilf, N., Kuttruff-Coqui, S., Frenzel, K., Bukur, V., Stevanović, S., Gouttefangeas, C., Platten, M., Tabatabai, G., Dutoit, V., van der Burg, S. H., thor Straten, P., Martínez-Ricarte, F., Ponsati, B., Okada, H., Lassen, U., Admon, A., Ottensmeier, C. H., Ulges, A., Kreiter, S., von Deimling, A. & 44 others, Skardelly, M., Migliorini, D., Kroep, J. R., Idorn, M., Rodon, J., Piró, J., Poulsen, H. S., Shraibman, B., McCann, K., Mendrzyk, R., Löwer, M., Stieglbauer, M., Britten, C. M., Capper, D., Welters, M. J. P., Sahuquillo, J., Kiesel, K., Derhovanessian, E., Rusch, E., Bunse, L., Song, C., Heesch, S., Wagner, C., Kemmer-Brück, A., Ludwig, J., Castle, J. C., Schoor, O., Tadmor, A. D., Green, E., Fritsche, J., Meyer, M., Pawlowski, N., Dorner, S., Hoffgaard, F., Rössler, B., Maurer, D., Weinschenk, T., Reinhardt, C., Huber, C., Rammensee, H. G., Singh-Jasuja, H., Sahin, U., Dietrich, P. Y. & Wick, W., 2019, In: Nature. 565, 7738, p. 240-245 6 p.

    Research output: Contribution to journalLetterResearchpeer-review

  52. Published

    Neoadjuvant bevacizumab and irinotecan versus bevacizumab and temozolomide followed by concomitant chemoradiotherapy in newly diagnosed glioblastoma multiforme: A randomized phase II study

    Hofland, K. F., Hansen, S., Sorensen, M., Engelholm, S., Schultz, H. P., Muhic, A., Grunnet, K., Ask, A., Costa, J. C., Kristiansen, C., Thomsen, C., Poulsen, H. S. & Lassen, Ulrik Niels, Jul 2014, In: Acta Oncologica. 53, 7, p. 939-944 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    A phase I study of concurrent chemoradiotherapy and cetuximab for locally advanced esophageal cancer

    Holländer, C., Baeksgaard, L., Sorensen, M., Albertsson, P., Damstrup, L. & Lassen, Ulrik Niels, Sep 2012, In: Anticancer Research. 32, 9, p. 4019-23 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Tisotumab Vedotin in Previously Treated Recurrent or Metastatic Cervical Cancer

    Hong, D. S., Concin, N., Vergote, I., de Bono, J. S., Slomovitz, B. M., Drew, Y., Arkenau, H-T., Machiels, J-P., Spicer, J. F., Jones, R., Forster, M. D., Cornez, N., Gennigens, C., Johnson, M. L., Thistlethwaite, F. C., Rangwala, R. A., Ghatta, S., Windfeld, K., Harris, J. R., Lassen, U. N. & 1 others, Coleman, R. L., 15 Mar 2020, In: Clinical Cancer Research. 26, 6, p. 1220-1228 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Larotrectinib versus prior therapies in tropomyosin receptor kinase fusion cancer: An intra-patient comparative analysis

    Italiano, A., Nanda, S., Briggs, A., Garcia-Foncillas, J., Lassen, Ulrik Niels, Vassal, G., Kummar, S., van Tilburg, C. M., Hong, D. S., Laetsch, T. W., Keating, K., Reeves, J. A., Fellous, M., Childs, B. H., Drilon, A. & Hyman, D. M., 2020, In: Cancers. 12, 11, p. 1-10 10 p., 3246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Extensive genomic analysis in patients with KRAS-mutated solid tumors shows high frequencies of concurrent alterations and potential targets but has limited clinical impact

    Jacobsen, I. C., Spanggaard, I., Højgaard, M., Belcaid, L., Qvortrup, Camilla, Yde, C. W., Schmidt, A. Y., Nielsen, Finn Cilius, Willemoe, G. L., Dam, M. S., Lassen, Ulrik Niels & Staal Rohrberg, K., 2022, In: Acta Oncologica. 61, 12, p. 1499-1506 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer

    Jacobsen, K., Bertran-Alamillo, J., Molina, M. A., Teixidó, C., Karachaliou, N., Pedersen, M. H., Castellví, J., Garzón, M., Codony-Servat, C., Codony-Servat, J., Giménez-Capitán, A., Drozdowskyj, A., Viteri, S., Larsen, M. R., Lassen, Ulrik Niels, Felip, E., Bivona, T. G., Ditzel, H. J. & Rosell, R., 2017, In: Nature Communications. 8, 14 p., 410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Irinotecan and bevacizumab in recurrent glioblastoma multiforme

    Jakobsen, J. N., Hasselbalch, B., Stockhausen, M., Lassen, Ulrik Niels & Poulsen, H. S., 1 Apr 2011, In: Expert Opinion on Pharmacotherapy. 12, 5, p. 825-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Late effects–the new focus of follow-up

    Johansen, Christoffer, von Heymann, A., Rafn, B. S., Borgquist, S., Christiansen, P., Christensen, P., Zachariae, R., Pappot, Helle & Lassen, Ulrik Niels, 2022, In: Acta Oncologica. 61, 10, p. 1163-1164

    Research output: Contribution to journalEditorialResearch

  60. Published

    Outcome of Bevacizumab Therapy in Patients with Recurrent Glioblastoma Treated with Angiotensin System Inhibitors

    Johansen, M. D., Urup, T., Holst, C. B., Christensen, I. J., Grunnet, K., Lassen, Ulrik Niels, Friis, S. & Poulsen, H. S., 2018, In: Cancer Investigation. 36, 9-10, p. 512-519 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    ProTarget: a Danish Nationwide Clinical Trial on Targeted Cancer Treatment based on genomic profiling – a national, phase 2, prospective, multi-drug, non-randomized, open-label basket trial

    Kringelbach, T., Højgaard, M., Rohrberg, K., Spanggaard, I., Laursen, Britt Elmedal, Ladekarl, M., Haslund, C. A., Harsløf, L., Belcaid, L., Gehl, Julie, Søndergaard, L., Eefsen, R. L., Hansen, K. H., Kodahl, A. R., Jensen, L. H., Holt, M. I., Oellegaard, T. H., Yde, C. W., Ahlborn, L. B. & Lassen, Ulrik Niels, 2023, In: BMC Cancer. 23, 1, 12 p., 182.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    TRK Inhibition: A New Tumor-Agnostic Treatment Strategy

    Kummar, S. & Lassen, Ulrik Niels, 2018, In: Targeted Oncology. 13, 5, p. 545-556

    Research output: Contribution to journalReviewResearchpeer-review

  63. Published

    Endoscopic ultrasound guided biopsy performed routinely in lung cancer staging spares futile thoracotomies: preliminary results from a randomised clinical trial

    Larsen, S. S., Vilmann, Peter, Krasnik, M., Dirksen, A., Clementsen, P., Maltbaek, N., Lassen, Ulrik Niels, Skov, B. G. & Jacobsen, G. K., Sep 2005, In: Lung Cancer. 49, 3, p. 377-85 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    A Comparison of Endoscopic Ultrasound Guided Biopsy and Positron Emission Tomography with Integrated Computed Tomography in Lung Cancer Staging

    Larsen, S. S., Vilmann, Peter, Krasnik, K., Dirksen, A., Clementsen, P., Skov, B. G., Jacobsen, G. K., Lassen, Ulrik Niels, Eigtved, A., Berthelsen, A. K., Mortensen, J. & Højgaard, Liselotte, Jan 2009, In: Current Health Sciences Journal. 35, 1, p. 5-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    A phase I, dose-escalation study of TB-403, a monoclonal antibody directed against PlGF, in patients with advanced solid tumours

    Lassen, Ulrik Niels, Nielsen, Dorte Lisbet, Sørensen, M., Winstedt, L., Niskanen, T., Stenberg, Y., Pakola, S., Stassen, J. & Glazer, S., 14 Feb 2012, In: B J C. 106, 4, p. 678-84 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Whole-body FDG-PET in patients with stage I non-seminomatous germ cell tumours

    Lassen, Ulrik Niels, Daugaard, G., Eigtved, A., Højgaard, L., Nielsen, K. D. & Rørth, M., 2003, In: European Journal of Nuclear Medicine and Molecular Imaging. 30, 3, p. 396-402 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Long-term survival in small-cell lung cancer: posttreatment characteristics in patients surviving 5 to 18+ years--an analysis of 1,714 consecutive patients

    Lassen, Ulrik Niels, Osterlind, K., Hansen, M., Dombernowsky, P., Bergman, B. & Hansen, H. H., May 1995, In: Journal of Clinical Oncology. 13, 5, p. 1215-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    18F-FDG whole body positron emission tomography (PET) in patients with unknown primary tumours (UPT)

    Lassen, Ulrik Niels, Daugaard, G., Eigtved, A., Damgaard, K. & Friberg, L., Jul 1999, In: European journal of cancer (Oxford, England : 1990). 35, 7, p. 1076-82 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Superiority of cisplatin or carboplatin in combination with teniposide and vincristine in the induction chemotherapy of small-cell lung cancer. A randomized trial with 5 years follow up

    Lassen, Ulrik Niels, Kristjansen, P. E., Osterlind, K., Bergman, B., Sigsgaard, T. C., Hirsch, F. R., Hansen, M., Dombernowsky, P. & Hansen, H. H., Apr 1996, In: Annals of Oncology. 7, 4, p. 365-71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    A phase II study of a 3-day schedule with topotecan and cisplatin every three weeks in patients with previously in treated small cell lung cancer and extensive disease: Final results.

    Lassen, Ulrik Niels, Sorensen, M., Jensen, P., Langer, Seppo W., Jensen, B., Jeppesen, N., Rytter, C., Mellemgaard, A., Hansen, Oddur & Osterlind, K., 15 Jul 2004, In: Journal of Clinical Oncology. 22, 14, p. 667S-667S 1 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  71. Published

    A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours

    Lassen, Ulrik Niels, Molife, L. R., Sorensen, J. M., Engelholm, S., Vidal, L., Sinha, R., Penson, R. T., Buhl-Jensen, P., Crowley, E., Tjornelund, J., Knoblauch, P., de Bono, J. S. & Buhl-Jensen, P., 29 Jun 2010, In: B J C. 103, 1, p. 12-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Surgery in limited stage small cell lung cancer

    Lassen, Ulrik Niels & Hansen, H. H., Apr 1999, In: Cancer Treatment Reviews. 25, 2, p. 67-72 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Treatment of newly diagnosed glioblastoma multiforme with carmustine, cisplatin and etoposide followed by radiotherapy. A phase II study

    Lassen, Ulrik Niels, Kristjansen, P. E., Wagner, A., Kosteljanetz, M. & Poulsen, H. S., Jun 1999, In: Journal of Neuro-Oncology. 43, 2, p. 161-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Phase I evaluation of the effects of ketoconazole and rifampicin on cediranib pharmacokinetics in patients with solid tumours

    Lassen, Ulrik Niels, Miller, W. H., Hotte, S., Evans, T. R. J., Kollmansberger, C., Adamson, D., Nielsen, Dorte Lisbet, Spicer, J., Chen, E., Meyer, T., Brown, K., Rafi, R. & Sawyer, M. B., 2013, In: Cancer Chemotherapy and Pharmacology. 71, 2, p. 543-549 7 p.

    Research output: Contribution to journalLetterResearchpeer-review

  75. Published

    Amantadin til influenza

    Lassen, Ulrik Niels & Hornsleth, A., 20 Jul 1992, In: Ugeskrift for Laeger. 154, 30, p. 2099-103 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Metabolic and hemodynamic evaluation of brain metastases from small cell lung cancer with positron emission tomography

    Lassen, Ulrik Niels, Andersen, P., Daugaard, G., Holm, S., Jensen, M., Svarer, C., Poulsen, H. S. & Paulson, Olaf B., Nov 1998, In: Clinical Cancer Research. 4, 11, p. 2591-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Brain metastases in small-cell lung cancer

    Lassen, Ulrik Niels, Kristjansen, P. E. & Hansen, H. H., Nov 1995, In: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 6, 9, p. 941-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Early death during chemotherapy in patients with small-cell lung cancer: derivation of a prognostic index for toxic death and progression

    Lassen, Ulrik Niels, Osterlind, K., Hirsch, F. R., Bergman, B., Dombernowsky, P. & Hansen, H. H., Feb 1999, In: B J C. 79, 3-4, p. 515-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Outcome of combination chemotherapy in extensive stage small-cell lung cancer: any treatment related progress?

    Lassen, Ulrik Niels, Hirsch, F. R., Osterlind, K., Bergman, B. & Dombernowsky, P., Jun 1998, In: Lung Cancer. 20, 3, p. 151-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Småcellet lungecancer

    Lassen, Ulrik Niels & Hansen, H. H., 5 Aug 1996, In: Ugeskrift for Laeger. 158, 32, p. 4517-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Phase II study of bevacizumab and temsirolimus combination therapy for recurrent glioblastoma multiforme

    Lassen, Ulrik Niels, Sorensen, M., Gaziel, T. B., Hasselbalch, B. & Poulsen, H. S., 2013, In: Anticancer Research. 33, 4, p. 1657-1660 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Combining PARP inhibition with PD-1 inhibitors

    Lassen, Ulrik Niels, 2019, In: The Lancet Oncology. 20, 9, p. 1196-1198 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  83. Published

    Phase 1 dose-escalation study of the antiplacental growth factor monoclonal antibody RO5323441 combined with bevacizumab in patients with recurrent glioblastoma

    Lassen, Ulrik Niels, Chinot, O. L., McBain, C., Mau-Sørensen, M., Larsen, V. A., Barrie, M., Roth, P., Krieter, O., Wang, K., Habben, K., Tessier, J., Lahr, A. & Weller, M., Jul 2015, In: Neuro-Oncology. 17, 7, p. 1007-15 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    A Phase I-II dose escalation study of fixed-dose rate gemcitabine, oxaliplatin and capecitabine every two weeks in advanced cholangiocarcinomas

    Lassen, Ulrik Niels, Jensen, L. H., Sorensen, M., Rohrberg, K. S., Ujmajuridze, Z. & Jakobsen, A., 1 Apr 2011, In: Acta Oncologica. 50, 3, p. 448-54 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    FDG-PET imaging in small cell lung cancer: any value?

    Lassen, Ulrik Niels, Jul 2002, In: Lung Cancer. 37, 1, p. 7

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Phase II study of bevacizumab and temsirolimus combination therapy for recurrent glioblastoma multiforme

    Lassen, Ulrik Niels, Sorensen, M., Gaziel, T. B., Hasselbalch, B. & Poulsen, H. S., Apr 2013, In: Anticancer Research. 33, 4, p. 1657-60 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Entrectinib for ROS1 fusion-positive NSCLC and NTRK fusion-positive solid tumours

    Lassen, Ulrik Niels, 2020, In: Lancet Oncology. 21, 2, p. 193-194

    Research output: Contribution to journalComment/debateResearch

  88. Published

    How I treat NTRK gene fusion-positive cancers

    Lassen, Ulrik Niels, 2019, In: ESMO Open. 4, Suppl. 2, 3 p., e000612.

    Research output: Contribution to journalReviewResearchpeer-review

  89. Published

    A phase I monotherapy study of RG7212, a first-in-class monoclonal antibody targeting TWEAK signaling in patients with advanced cancers

    Lassen, Ulrik Niels, Meulendijks, D., Siu, L. L., Karanikas, V., Mau-Sorensen, M., Schellens, J. H. M., Jonker, D. J., Hansen, A. R., Simcox, M. E., Schostack, K. J., Bottino, D., Zhong, H., Roessler, M., Vega-Harring, S. M., Jarutat, T., Geho, D., Wang, K., DeMario, M. & Goss, G. D., 15 Jan 2015, In: Clinical Cancer Research. 21, 2, p. 258-66 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Transcriptomics in Tumor and Normal Lung Tissues Identify Patients With Early-Stage Non–Small-Cell Lung Cancer With High Risk of Postsurgery Recurrence Who May Benefit From Adjuvant Therapies

    Lazar, V., Girard, N., Raymond, E., Martini, J., Galbraith, S., Raynaud, J., Bresson, C., Solomon, B., Magidi, S., Nechushtan, H., Onn, A., Berger, R., Chen, H., Al-omari, A., Ikeda, S., Lassen, U., Sekacheva, M., Felip, E., Tabernero, J., Batist, G. & 10 others, Spatz, A., Pramesh, C. S., Girard, P., Blay, J., Philip, T., Berindan-neagoe, I., Porgador, A., Rubin, E., Kurzrock, R. & Schilsky, R. L., 2022, In: JCO Precision Oncology. 6, 12 p., e2200072.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Comorbidity between lung cancer and COVID-19 pneumonia: role of immunoregulatory gene transcripts in high ACE2-expressing normal lung

    Lazar, V., Raynaud, J., Magidi, S., Bresson, C., Martini, J. F., Galbraith, S., Wunder, F., Onn, A., Batist, G., Girard, N., Lassen, U., Pramesh, C. S., Al-Omari, A., Ikeda, S., Berchem, G., Blay, J. Y., Solomon, B., Felip, E., Tabernero, J., Rubin, E. & 5 others, Philip, T., Porgador, A., Berindan-Neagoe, I., Schilsky, R. L. & Kurzrock, R., 2022, In: Therapeutic Advances in Medical Oncology. 14, p. 1-15 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Total burden of disease in cancer patients at diagnosis—a Danish nationwide study of multimorbidity and redeemed medication

    Loeppenthin, K., Dalton, Susanne Oksbjerg, Johansen, Christoffer, Andersen, E., Christensen, Mikkel Bring, Pappot, Helle, Petersen, L. N., Thisted, L. B., Frølich, A., Mortensen, C. E., Lassen, Ulrik Niels, Ørsted, J. & Bidstrup, P. E., 15 Sep 2020, In: British Journal of Cancer. 123, 6, p. 1033-1040 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma

    Lokhorst, H. M., Plesner, T., Laubach, J. P., Nahi, H., Gimsing, P., Hansson, M., Minnema, M. C., Lassen, U., Krejcik, J., Palumbo, A., van de Donk, N. W. C. J., Ahmadi, T., Khan, I., Uhlar, C. M., Wang, J., Sasser, A. K., Losic, N., Lisby, S., Basse, L., Brun, N. & 1 others, Richardson, P. G., 24 Sep 2015, In: New England Journal of Medicine. 373, 13, p. 1207-19 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer

    Massard, C., Azaro, A., Soria, J., Lassen, Ulrik Niels, Le Tourneau, C., Sarker, D., Smith, C., Ohnmacht, U., Oakley, G., Patel, B. K. R., Yuen, E. S. M., Benhadji, K. A. & Rodon, J., 2018, In: Annals of oncology : official journal of the European Society for Medical Oncology. 29, 9, p. 1911-1917 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. A phase I trial of intravenous catumaxomab: a bispecific monoclonal antibody targeting EpCAM and the T cell coreceptor CD3

    Mau-Sørensen, M., Dittrich, C., Dienstmann, R., Lassen, Ulrik Niels, Büchler, W., Martinius, H. & Tabernero, J., May 2015, In: Cancer Chemotherapy and Pharmacology. 75, 5, p. 1065-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Dynamics of mutant BRAF V600E in free circulating DNA (fcDNA) of non-melanoma cancer patients (pts) in response to treatment with BRAF and MEK/EGFR inhibitors

    Mau-Sørensen, M., Ahlborn, L. B., Jønson, L., Oestrup, O., Hasselby, Jane Preuss, Santoni Rugiu, Eric, Nielsen, Finn Cilius, Lassen, Ulrik Niels & Yde, C. W., 2016, In: Journal of Clinical Oncology. 34, 15 (Suppl. S), 11531.

    Research output: Contribution to journalConference abstract in journalResearch

  97. Published

    Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity

    Meulendijks, D., Jacob, W., Voest, E. E., Mau-Sorensen, M., Martinez-Garcia, M., Taus, A., Fleitas, T., Cervantes, A., Lolkema, M. P., Langenberg, M. H. G., De Jonge, M. J., Sleijfer, S., Han, J-Y., Calles, A., Felip, E., Kim, S-W., Schellens, J. H. M., Wilson, S., Thomas, M., Ceppi, M. & 11 others, Meneses-Lorente, G., James, I., Vega-Harring, S., Dua, R., Nguyen, M., Steiner, L., Adessi, C., Michielin, F., Bossenmaier, B., Weisser, M. & Lassen, Ulrik Niels, 2017, In: Clinical Cancer Research. 23, 18, p. 5406-5415

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors

    Meulendijks, D., Jacob, W., Martinez-Garcia, M., Taus, A., Lolkema, M. P., Voest, E. E., Langenberg, M. H. G., Fleitas Kanonnikoff, T., Cervantes, A., De Jonge, M. J., Sleijfer, S., Mau-Sørensen, M., Thomas, M., Ceppi, M., Meneses-Lorente, G., James, I., Adessi, C., Michielin, F., Abiraj, K., Bossenmaier, B. & 3 others, Schellens, J. H. M., Weisser, M. & Lassen, Ulrik Niels, 15 Feb 2016, In: Clinical Cancer Research. 22, 4, p. 877-85 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors

    Meulendijks, D., Lassen, Ulrik Niels, Siu, L. L., Huitema, A. D. R., Karanikas, V., Mau-Sørensen, M., Jonker, D. J., Hansen, A. R., Simcox, M. E., Schostack, K. J., Bottino, D., Zhong, H., Roessler, M., Vega-Harring, S. M., Jarutat, T., Geho, D., Wang, K., DeMario, M., Goss, G. D. & Schellens, J. H. M., 15 Feb 2016, In: Clinical Cancer Research. 22, 4, p. 858-67 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance

    Michaelsen, Signe Regner, Staberg, M., Pedersen, H., Jensen, K. E., Majewski, W., Broholm, H., Nedergaard, M. K., Meulengracht, C., Urup, T., Villingshøj, M., Lukacova, S., Skjøth-Rasmussen, J., Brennum, J., Kjær, Andreas, Lassen, Ulrik Niels, Stockhausen, M., Poulsen, H. S. & Hamerlik, P., 2018, In: Neuro-Oncology. 20, 11, p. 1462-1474

    Research output: Contribution to journalJournal articleResearchpeer-review

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