Seppo W. Langer
Clinical Associate Professor
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Expression of Mutated p53 Protein in Gastroenteropancreatic Neuroendocrine Carcinoma (WHO G3)
Ali, A., Gronberg, M., Federspiel, B., Hjortland, G. O., Ladekarl, M., Langer, Seppo W., Welin, S., Knigge, Ulrich, Sorbye, H., Grimelius, L. & Janson, T. E., 2016, In: Neuroendocrinology. 103, p. 43 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
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Intravenous versus Oral Etoposide: Efficacy and Correlation to Clinical Outcome in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms (WHO G3)
Ali, A. A., Gronberg, M., Hjortland, G. O., Grønbæk, H., Ladekarl, M., Langer, Seppo W., Welin, S., Vestermark, L. W., Osterlund, P., Knigge, Ulrich, Sorbye, H. & Janson, E. T., 2018, p. 184-184. 1 p.Research output: Contribution to conference › Poster › Research › peer-review
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PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3
Ali, A. S., Langer, Seppo W., Federspiel, B., Hjortland, G. O., Grønbæk, H., Ladekarl, M., Welin, S., Weber Vestermark, L., Arola, J., Osterlund, P., Knigge, Ulrich, Sørbye, H., Micke, P., Grimelius, L., Grönberg, M. & Tiensuu Janson, E., 2020, In: PLoS ONE. 15, 12, 12 p., e0243900.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of p53 protein in high-grade gastroenteropancreatic neuroendocrine carcinoma
Ali, A. S., Grönberg, M., Federspiel, B., Scoazec, J. Y., Hjortland, G. O., Grønbæk, H., Ladekarl, M., Langer, Seppo W., Welin, S., Vestermark, L. W., Arola, J., Österlund, P., Knigge, Ulrich, Sorbye, H., Grimelius, L. & Janson, E. T., Nov 2017, In: PLOS ONE. 12, 11, 15 p., e0187667.Research output: Contribution to journal › Journal article › Research › peer-review
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Intravenous versus oral etoposide: efficacy and correlation to clinical outcome in patients with high-grade metastatic gastroenteropancreatic neuroendocrine neoplasms (WHO G3)
Ali, A. S., Grönberg, M., Langer, Seppo W., Ladekarl, M., Hjortland, G. O., Vestermark, L. W., Österlund, P., Welin, S., Grønbæk, H., Knigge, Ulrich, Sorbye, H. & Janson, E. T., 2018, In: Medical Oncology. 35, 4, p. 1-7 7 p., 47.Research output: Contribution to journal › Journal article › Research › peer-review
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Surgical management, pre-operative tumor localization and histopathology of 80 patients operated for insulinoma.
Andreassen, Mikkel, Ilett, E., Wiese, D., Slater, E., Klose, M., Hansen, C., Gercke, N., Langer, Seppo W., Kjær, Andreas, Maurer, E., Federspiel, B., Kann, P., Bartsch, D. & Knigge, Ulrich, 2019, In: Journal of Clinical Endocrinology and Metabolism. p. 6129–6138Research output: Contribution to journal › Journal article › Research › peer-review
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Immunohistochemical Profiles in 81 Patients with Resected Insulinomas
Andreassen, Mikkel, Ilett, E., Slater, E. P., Wiese, D., Hansen, C. P., Gehrke, N., Langer, Seppo W., Kjær, Andreas, Maurer, E., Federspiel, B., Bartsch, D. K. & Knigge, Ulrich, 2018, p. 136-136. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Surgical Management, Preoperative Tumor Localization, and Histopathology of 80 Patients Operated on for Insulinoma
Andreassen, Mikkel, Ilett, E., Wiese, D., Slater, E. P., Klose, M., Hansen, C. P., Gercke, N., Langer, Seppo W., Kjaer, A., Maurer, E., Federspiel, B., Kann, P. H., Bartsch, D. K. & Knigge, Ulrich, Dec 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6129-6138Research output: Contribution to journal › Journal article › Research › peer-review
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Brain relapses in chemotherapy-treated small cell lung cancer: A retrospective review of two time-dose regimens of therapeutic brain irradiation
Bach, F., Sørensen, Jens Benn, Adrian, L., Larsen, H., Langer, Seppo W., Nelausen, K. M. & Engelholm, S. A., Sep 1996, In: Lung Cancer. 15, 2, p. 171-181 11 p.Research output: Contribution to journal › Review › Research › peer-review
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Limited Diagnostic Utility of Chromogranin A Measurements in Workup of Neuroendocrine Tumors
Baekdal, J., Krogh, J., Klose, M., Holmager, P., Langer, Seppo W., Oturai, P., Kjær, Andreas, Federspiel, B., Hilsted, L., Rehfeld, Jens Frederik, Knigge, U. & Andreassen, Mikkel, 2020, In: Diagnostics. 10, 11, 13 p., 881.Research output: Contribution to journal › Journal article › Research › peer-review
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FDG-PET Is Superior to WHO Grading in Predicting Overall Survival of Patients with Neuroendocrine Tumors: A Prospective Study of 172 Patients
Binderup, Tina, Johnbeck, C. B., Loft, A., Berthelsen, A. K., Federspiel, B., Langer, Seppo W., Knigge, Ulrich & Kjær, Andreas, 2017, In: Neuroendocrinology. 105, p. 164-164 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
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18F-FDG-PET is superior to WHO grading as prognostic tool in neuroendocrine neoplasms and useful in guiding peptide receptor radionuclide therapy: a prospective 10-year follow-up study of 166 patients
Binderup, Tina, Knigge, U., Johnbeck, C. B., Loft, A., Berthelsen, A. K., Oturai, P., Mortensen, Jann, Federspiel, B., Langer, Seppo W. & Kjær, Andreas, 2021, In: The Journal of Nuclear Medicine. 62, 6, p. 808-815 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy and Safety of Rovalpituzumab Tesirine Compared with Topotecan as Second-Line Therapy in DLL3-High Small Cell Lung Cancer: Results from the Phase 3 TAHOE Study
Blackhall, F., Jao, K., Greillier, L., Cho, B. C., Penkov, K., Reguart, N., Majem, M., Nackaerts, K., Syrigos, K., Hansen, K., Schuette, W., Cetnar, J., Cappuzzo, F., Okamoto, I., Erman, M., Langer, S. W., Kato, T., Groen, H., Sun, Z., Luo, Y. & 4 others, , 2021, In: Journal of Thoracic Oncology. 16, 9, p. 1547-1558Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metastasizing malignant pleomorphic adenoma in a young man
Bourke, J. L., Langer, Seppo W. & Jensen, H. L., Jul 2007, In: Acta Pathologica et Microbiologica Scandinavica - Section A Pathology. 115, 7, p. 866-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prospective phase II trial of prognostication by 68Ga-NOTA-AE105 uPAR PET in patients with neuroendocrine neoplasms: Implications for uPAR targeted therapy
Carlsen, Esben Andreas, Loft, Mathias Hougaard, Loft, A., Berthelsen, A. K., Langer, Seppo W., Knigge, Ulrich & Kjær, Andreas, 2022, In: Journal of Nuclear Medicine. 63, 9, p. 1371-1377Research output: Contribution to journal › Journal article › Research › peer-review
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Semi-automatic tumor delineation for evaluation of 64Cu-DOTATATE PET/CT in patients with neuroendocrine neoplasms: prognostication based on lowest lesion uptake and total tumor volume
Carlsen, Esben Andreas, Johnbeck, C. B., Loft, Mathias Hougaard, Pfeifer, A., Oturai, P., Langer, Seppo W., Knigge, Ulrich, Ladefoged, C. N. & Kjær, Andreas, 2021, In: The Journal of Nuclear Medicine. 62, 11, p. 1564-1570Research output: Contribution to journal › Journal article › Research › peer-review
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64Cu-DOTATATE PET/CT and Prediction of Overall and Progression-Free Survival in Patients with Neuroendocrine Neoplasms
Carlsen, E. A., Johnbeck, C. B., Binderup, Tina, Loft, M., Pfeifer, A., Mortensen, Jann, Oturai, P., Loft, A., Berthelsen, A. K., Langer, Seppo W., Knigge, U. & Kjær, Andreas, 2020, In: The Journal of Nuclear Medicine. 61, 10, p. 1491-1497Research output: Contribution to journal › Journal article › Research › peer-review
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Prospective Phase II Trial of [68Ga]Ga-NODAGA-E[c(RGDyK)]2 PET/CT Imaging of Integrin αvβ3 for Prognostication in Patients with Neuroendocrine Neoplasms
Carlsen, E. A., Loft, M., Loft, A., Czyzewska, D., Andreassen, Mikkel, Langer, Seppo W., Knigge, Ulrich & Kjær, Andreas, 2023, In: The Journal of Nuclear Medicine. 64, 2, p. 252-259Research output: Contribution to journal › Journal article › Research › peer-review
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A convolutional neural network for total tumor segmentation in [64Cu]Cu-DOTATATE PET/CT of patients with neuroendocrine neoplasms
Carlsen, E. A., Lindholm, Kristian, Hindsholm, A., Gæde, M., Ladefoged, C. N., Loft, M., Johnbeck, C. B., Langer, Seppo W., Oturai, P., Knigge, Ulrich, Kjær, Andreas & Andersen, Flemming Littrup, 2022, In: EJNMMI Research. 12, 1, p. 1-10 30.Research output: Contribution to journal › Journal article › Research › peer-review
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Incidence and Clinicopathological Features of Colorectal Neuroendocrine Carcinomas and Mixed Neuroendocrine-Nonneuroendocrine Neoplasms
Chiranth, D. J., Willemoe, G. L., Garbyal, Rajendra Singh, Melchior, L. C., Knigge, Ulrich, Langer, Seppo W. & Federspiel, B., 2019, In: Neuroendocrinology. 108, S1, p. 103-103 1 p., E01.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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A systematic review of targeted therapy for vestibular schwannoma in patients with NF2-related schwannomatosis
Chiranth, S., Langer, Seppo W., Poulsen, H. S. & Urup, T., 2023, In: Neuro-Oncology Advances. 5, 1, vdad099.Research output: Contribution to journal › Review › Research › peer-review
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FLT-PET And FDG-PET/CT For The Detection Of Relapse Following Definitive Radiotherapy In Non-small Cell Lung Cancer: Preliminary Results
Christensen, T., Langer, Seppo W., Larsen, K., Persson, Gitte F., Amtoft, A. G., Johannesen, H., Keller, S., Kjær, Andreas & Fischer, Barbara Malene Bjerregaard, 2019, In: Journal of Thoracic Oncology. 13, 105, p. S672 P2.01-20.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Impact of [18F]FDG-PET and [18F]FLT-PET-Parameters in Patients with Suspected Relapse of Irradiated Lung Cancer
Christensen, T. N., Langer, Seppo W., Persson, Gitte F., Larsen, Klaus Richter, Amtoft, A. G., Keller, S. H., Kjær, Andreas & Fischer, Barbara Malene Bjerregaard, 2021, In: Diagnostics. 11, 2, 279.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
18F-FLT-PET/CT adds value to 18F-FDG-PET/CT for diagnosing relapse after definitive radiotherapy in patients with lung cancer. Results of a prospective clinical trial
Christensen, T. N., Langer, Seppo W., Persson, Gitte F., Larsen, Klaus Richter, Loft, A., Amtoft, A. G., Berthelsen, A. K., Johannesen, H. H., Keller, S. H., Kjær, Andreas & Fischer, Barbara Malene Bjerregaard, 2021, In: The Journal of Nuclear Medicine. 62, 5, p. 628-635 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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18F-fluorothymidine (FLT)-PET and diffusion-weighted MRI for early response evaluation in patients with small cell lung cancer: a pilot study
Christensen, T. N., Langer, Seppo W., Villumsen, K. E., Johannesen, H. H., Löfgren, J., Keller, S. H., Hansen, Adam Espe, Kjær, Andreas & Fischer, Barbara Malene Bjerregaard, Dec 2020, In: European Journal of Hybrid Imaging - EJNMMI Multimodality Journal. 4, 1, 20 p., 2.Research output: Contribution to journal › Journal article › Research › peer-review
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Prognostic Value of 18F-FDG-PET Parameters in Patients with Small Cell Lung Cancer: A Meta-Analysis and Review of Current Literature
Christensen, T. N., Andersen, Per Kragh, Langer, Seppo W. & Fischer, Barbara Malene Bjerregaard, 26 Jan 2021, In: Diagnostics. 11, 2, 24 p., 174.Research output: Contribution to journal › Review › Research › peer-review
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Prognostic value of18 f–fdg–pet parameters in patients with small cell lung cancer: A meta-analysis and review of current literature
Christensen, T. N., Andersen, Per Kragh, Langer, Seppo W. & Fischer, Barbara Malene Bjerregaard, 2021, In: Diagnostics. 11, 2, 24 p., 174.Research output: Contribution to journal › Review › Research › peer-review
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DLL3 expression and clinico-pathological data in 247 patients with NEN
Clausen, Malene Martini, Federspiel, B., Carstensen, F., Suppli, M. H., Kjær, Andreas, Andreassen, Mikkel, Garbyal, Rajendra Singh, Knigge, Ulrich & Langer, Seppo W., 2022, In: Journal of Neuroendocrinology. 34, S1, p. 104 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
Improving the prognosis for lung cancer patients
Clausen, M. M. & Langer, Seppo W., Aug 2019, In: Acta Oncologica. 58, 8, p. 1077-1078Research output: Contribution to journal › Editorial › Research
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Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms
Dam, G., Grønbæk, H., Sundlöv, A., Botling, J., Sundin, A., Petersen, René Horsleben, Welin, S., Evensen, E., Sorbye, H., Tabaksblat, E., Arveschoug, A. K., Mortensen, Jann, Kjær, Andreas, Knigge, Ulrich, Tiensuu Janson, E. & Langer, Seppo W., 16 May 2023, In: Acta Oncologica. 62, 5, p. 431-437 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Asbestos-induced lung injury among Danish jewelry workers
Døssing, M. & Langer, Seppo W., Dec 1994, In: American Journal of Industrial Medicine. 26, 6, p. 755-8 4 p.Research output: Contribution to journal › Review › Research › peer-review
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A Consensus Developed Morphological Re-evaluation of 196 Cases with Metastatic High-grade Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NEN G3) from the Nordic NEC Registries: Consequences for Classification, Treatment Response and Survival
Elvebakken, H., Perren, A., Scoazec, J. Y., Tang, L. H., Federspiel, B., Vestermark, L., Zlobec, I., Hjortland, G. O., Langer, Seppo W., Gronbaek, H., Janson, T. E. & Sorbye, H., 2019, p. 149. 1 p.Research output: Contribution to conference › Poster › Research
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A consensus developed morphological re-evaluation of 196 high-grade gastroenteropancreatic neuroendocrine neoplasms and its clinical correlations
Elvebakken, H., Perren, A., Scoazec, J., Tang, L. H., Federspiel, B., Klimstra, D. S., Vestermark, L. W., Ali, A. S., Zlobec, I., Myklebust, T. Å., Hjortland, G. O., Langer, Seppo W., Gronbæk, H., Knigge, Ulrich, Tiensuu Janson, E. & Sorbye, H., 2021, In: Neuroendocrinology. 111, p. 883–894Research output: Contribution to journal › Journal article › Research › peer-review
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A prospective study of PET/CT in initial staging of small-cell lung cancer: comparison with CT, bone scintigraphy and bone marrow analysis
Fischer, Barbara Malene Bjerregaard, Mortensen, J., Langer, Seppo W., Loft, A., Berthelsen, A. K., Petersen, B. I., Daugaard, G., Lassen, Ulrik Niels & Hansen, H. H., Feb 2007, In: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 18, 2, p. 338-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PET in staging of patients with small cell lung cancer - preliminary results
Fischer, Barbara Malene Bjerregaard, Mortensen, Jann, Langer, Seppo W., Eigtved, A., Berthelsen, A., Lassen, Ulrik Niels, Daugaard, G. & Hansen, H., Aug 2004, In: European Journal of Nuclear Medicine and Molecular Imaging. 31, p. S352-S352 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
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PET/CT imaging in response evaluation of patients with small cell lung cancer
Fischer, Barbara Malene Bjerregaard, Mortensen, Jann, Langer, Seppo W., Loft, A., Berthelsen, A. K., Daugaard, G., Lassen, Ulrik Niels & Hansen, H. H., Oct 2006, In: Lung Cancer. 54, 1, p. 41-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Results after surgical treatment of liver metastases in patients with high-grade gastroenteropancreatic neuroendocrine carcinomas
Galleberg, R. B., Knigge, Ulrich, Tiensuu Janson, E., Vestermark, L. W., Haugvik, S., Ladekarl, M., Langer, Seppo W., Grønbæk, H., Österlund, P., Hjortland, G. O., Assmus, J., Tang, L., Perren, A. & Sorbye, H., 2017, In: European Journal of Surgical Oncology. 43, 9, p. 1682-1689Research output: Contribution to journal › Journal article › Research › peer-review
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Resection of Liver Metastases in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Carcinomas: A Nordic Multicenter Study
Galleberg, R. B., Knigge, Ulrich, Janson, E. T., Vestermark, L. W., Haugvik, S. P., Ladekarl, M., Langer, Seppo W., Grønbæk, H., Osterlund, P., Hjortland, G., Assmus, J., Tang, L., Perren, A. & Sorbye, H., 2017, In: Neuroendocrinology. 105, p. 264 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
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Incidence and survival from lung cancer in Greenland is comparable to survival in the Nordic countries
Gelvan, A., Risum, S. & Langer, Seppo W., Apr 2015, In: Danish Medical Journal. 62, 4, p. A5033Research output: Contribution to journal › Journal article › Research › peer-review
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Chirurgische Behandlung von Paravasaten
Goertz, O., Hirsch, T., Ring, A., Daigeler, A., Hauser, J., Langer, Seppo W., Steinstraesser, L. & Steinau, H. U., Dec 2014, In: Zentralblatt fur Chirurgie - Zeitschrift fur Allgemeine, Viszeral- und Gefasschirurgie. 139, Supplement 2, p. e103-e108 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Results of 252 Patients with Bronchopulmonary Neuroendocrine Tumors Treated at the Copenhagen NET Centre of Excellence
Groendahl, Knigge, Ulrich, Langer, Seppo W., Kjær, Andreas, Federspiel, B., Petersen, René Horsleben, Binderup, Tina & Nielsen, K., 2018, p. 289-289. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Randomized Phase II Study of Maintenance Enzastaurin Following Whole Brain Radiation Therapy in the Treatment of Brain Metastases From Lung Cancer - the MENZA Study
Gronberg, B., Ciuleanu, T., Flotten, O., Knuuttila, A., Abel, E., Langer, Seppo W., Munoz, M., Hahka-Kemppinen, M. & Sundstrom, S., Sep 2011, p. S612-S612. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Twice-daily chemoradiotherapy in limited-stage small-cell lung cancer - Authors' reply
Grønberg, B. H., Langer, Seppo W., Nyman, J. & Halvorsen, T. O., Jun 2021, In: Lancet Oncology. 22, 6, e222.Research output: Contribution to journal › Comment/debate › Research › peer-review
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A placebo-controlled, randomized phase II study of maintenance enzastaurin following whole brain radiation therapy in the treatment of brain metastases from lung cancer
Grønberg, B. H., Ciuleanu, T., Fløtten, Ø., Knuuttila, A., Abel, E., Langer, Seppo W., Krejcy, K., Liepa, A. M., Munoz, M., Hahka-Kemppinen, M. & Sundstrøm, S., Oct 2012, In: Lung Cancer. 78, 1, p. 63-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-dose versus standard-dose twice-daily thoracic radiotherapy for patients with limited stage small-cell lung cancer: an open-label, randomised, phase 2 trial
Grønberg, B. H., Killingberg, K. T., Fløtten, Ø., Brustugun, O. T., Hornslien, K., Madebo, T., Langer, Seppo W., Schytte, T., Nyman, J., Risum, S., Tsakonas, G., Engleson, J. & Halvorsen, T. O., 2021, In: Lancet Oncology. 22, 3, p. 321-331 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characteristics of 252 patients with bronchopulmonary neuroendocrine tumours treated at the Copenhagen NET Centre of Excellence
Grøndahl, V., Binderup, Tina, Langer, Seppo W., Petersen, René Horsleben, Nielsen, K., Kjær, Andreas, Federspiel, B. & Knigge, Ulrich, 2019, In: Lung Cancer. 132, p. 141-149 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nuclear Molecular Imaging Strategies in Immune Checkpoint Inhibitor Therapy
Guldbrandsen, K. F., Hendel, Helle Westergren, Langer, Seppo W. & Fischer, Barbara Malene Bjerregaard, 2017, In: Diagnostics. 7, 2, 12 p., 23.Research output: Contribution to journal › Review › Research › peer-review
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Behandling af neuroendokrine gastrointestinale tumorer
Hansen, C. P., Langer, Seppo W., Frevert, S., Mortensen, Jann, Kjær, Andreas & Knigge, Ulrich, 25 Oct 2010, In: Ugeskrift for Laeger. 172, 43, p. 2942-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Behandling af neuroendokrine gastrointestinale tumorer
Hansen, C. P., Langer, Seppo W., Frevert, S., Mortensen, Jann, Kjær, Andreas & Knigge, Ulrich, 25 Oct 2010, In: Ugeskrift for Laeger. 172, 43, p. 2942-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Surgical Treatment as a Principle for Patients with High-Grade Pancreatic Neuroendocrine Carcinoma: A Nordic Multicenter Comparative Study
Haugvik, S. P., Janson, E. T., Österlund, P., Langer, Seppo W., Falk, R. S., Labori, K. J., Vestermark, L. W., Grønbaek, H., Gladhaug, I. P. & Sorbye, H., 1 May 2016, In: Annals of Surgical Oncology. 23, 5, p. 1721-1728 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early Initiated Postoperative Rehabilitation Reduces Fatigue in Patients with Operable Lung Cancer: A Randomized Trial
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Perioperative Rehabilitation in Operable Lung Cancer Patients (PROLUCA): A Feasibility Study
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Nuclear Molecular Imaging Strategies in Immune Checkpoint Inhibitor Therapy
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