Ulrik Niels Lassen
Clinical Professor
- 1992
- Published
Amantadin til influenza
Lassen, Ulrik Niels & Hornsleth, A., 20 Jul 1992, In: Ugeskrift for Laeger. 154, 30, p. 2099-103 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Long-term survival in small-cell lung cancer: posttreatment characteristics in patients surviving 5 to 18+ years--an analysis of 1,714 consecutive patients
Lassen, Ulrik Niels, Osterlind, K., Hansen, M., Dombernowsky, P., Bergman, B. & Hansen, H. H., May 1995, In: Journal of Clinical Oncology. 13, 5, p. 1215-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain metastases in small-cell lung cancer
Lassen, Ulrik Niels, Kristjansen, P. E. & Hansen, H. H., Nov 1995, In: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 6, 9, p. 941-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Superiority of cisplatin or carboplatin in combination with teniposide and vincristine in the induction chemotherapy of small-cell lung cancer. A randomized trial with 5 years follow up
Lassen, Ulrik Niels, Kristjansen, P. E., Osterlind, K., Bergman, B., Sigsgaard, T. C., Hirsch, F. R., Hansen, M., Dombernowsky, P. & Hansen, H. H., Apr 1996, In: Annals of Oncology. 7, 4, p. 365-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Småcellet lungecancer
Lassen, Ulrik Niels & Hansen, H. H., 5 Aug 1996, In: Ugeskrift for Laeger. 158, 32, p. 4517-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Current therapy of small cell lung cancer
Sorensen, M., Lassen, Ulrik Niels & Hansen, H. H., Mar 1998, In: Current Opinion in Oncology. 10, 2, p. 133-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Outcome of combination chemotherapy in extensive stage small-cell lung cancer: any treatment related progress?
Lassen, Ulrik Niels, Hirsch, F. R., Osterlind, K., Bergman, B. & Dombernowsky, P., Jun 1998, In: Lung Cancer. 20, 3, p. 151-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic and hemodynamic evaluation of brain metastases from small cell lung cancer with positron emission tomography
Lassen, Ulrik Niels, Andersen, P., Daugaard, G., Holm, S., Jensen, M., Svarer, C., Poulsen, H. S. & Paulson, Olaf B., Nov 1998, In: Clinical Cancer Research. 4, 11, p. 2591-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Early death during chemotherapy in patients with small-cell lung cancer: derivation of a prognostic index for toxic death and progression
Lassen, Ulrik Niels, Osterlind, K., Hirsch, F. R., Bergman, B., Dombernowsky, P. & Hansen, H. H., Feb 1999, In: B J C. 79, 3-4, p. 515-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surgery in limited stage small cell lung cancer
Lassen, Ulrik Niels & Hansen, H. H., Apr 1999, In: Cancer Treatment Reviews. 25, 2, p. 67-72 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of newly diagnosed glioblastoma multiforme with carmustine, cisplatin and etoposide followed by radiotherapy. A phase II study
Lassen, Ulrik Niels, Kristjansen, P. E., Wagner, A., Kosteljanetz, M. & Poulsen, H. S., Jun 1999, In: Journal of Neuro-Oncology. 43, 2, p. 161-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
18F-FDG whole body positron emission tomography (PET) in patients with unknown primary tumours (UPT)
Lassen, Ulrik Niels, Daugaard, G., Eigtved, A., Damgaard, K. & Friberg, L., Jul 1999, In: European journal of cancer (Oxford, England : 1990). 35, 7, p. 1076-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
FDG-PET imaging in small cell lung cancer: any value?
Lassen, Ulrik Niels, Jul 2002, In: Lung Cancer. 37, 1, p. 7Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Whole-body FDG-PET in patients with stage I non-seminomatous germ cell tumours
Lassen, Ulrik Niels, Daugaard, G., Eigtved, A., Højgaard, L., Nielsen, K. D. & Rørth, M., 2003, In: European Journal of Nuclear Medicine and Molecular Imaging. 30, 3, p. 396-402 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
The role of nuclear medicine in the diagnosis of cancer of unknown origin
Demir, H., Berk, F., Raderer, M., Plowman, P. N., Lassen, Ulrik Niels, Daugaard, G., Clausen, M., Bohuslavizki, K. H., Peters, M., Harmer, C., Malamitsi, J. & Aktolun, C., Jun 2004, In: American Journal of Nuclear Medicine and Molecular Imaging. 48, 2, p. 164-73 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phase II study of a 3-day schedule with topotecan and cisplatin every three weeks in patients with previously in treated small cell lung cancer and extensive disease: Final results.
Lassen, Ulrik Niels, Sorensen, M., Jensen, P., Langer, Seppo W., Jensen, B., Jeppesen, N., Rytter, C., Mellemgaard, A., Hansen, Oddur & Osterlind, K., 15 Jul 2004, In: Journal of Clinical Oncology. 22, 14, p. 667S-667S 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
PET in staging of patients with small cell lung cancer - preliminary results
Fischer, Barbara Malene Bjerregaard, Mortensen, Jann, Langer, Seppo W., Eigtved, A., Berthelsen, A., Lassen, Ulrik Niels, Daugaard, G. & Hansen, H., Aug 2004, In: European Journal of Nuclear Medicine and Molecular Imaging. 31, p. S352-S352 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
- 2005
- Published
Endoscopic ultrasound guided biopsy performed routinely in lung cancer staging spares futile thoracotomies: preliminary results from a randomised clinical trial
Larsen, S. S., Vilmann, Peter, Krasnik, M., Dirksen, A., Clementsen, P., Maltbaek, N., Lassen, Ulrik Niels, Skov, B. G. & Jacobsen, G. K., Sep 2005, In: Lung Cancer. 49, 3, p. 377-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
A prospective PET study of patients with glioblastoma multiforme
Andersen, P. B., Blinkenberg, M., Lassen, Ulrik Niels, Kosteljanetz, M., Wagner, A., Poulsen, H. S., Sørensen, Per Soelberg & Paulson, Olaf B., Jun 2006, In: Acta Neurologica Scandinavica. 113, 6, p. 412-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PET/CT imaging in response evaluation of patients with small cell lung cancer
Fischer, Barbara Malene Bjerregaard, Mortensen, Jann, Langer, Seppo W., Loft, A., Berthelsen, A. K., Daugaard, G., Lassen, Ulrik Niels & Hansen, H. H., Oct 2006, In: Lung Cancer. 54, 1, p. 41-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
A prospective study of PET/CT in initial staging of small-cell lung cancer: comparison with CT, bone scintigraphy and bone marrow analysis
Fischer, Barbara Malene Bjerregaard, Mortensen, J., Langer, Seppo W., Loft, A., Berthelsen, A. K., Petersen, B. I., Daugaard, G., Lassen, Ulrik Niels & Hansen, H. H., Feb 2007, In: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 18, 2, p. 338-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Phase II study of a 3-day schedule with topotecan and cisplatin in patients with previously untreated small cell lung cancer and extensive disease
Sorensen, M., Lassen, Ulrik Niels, Jensen, P. B., Østerlind, K. E., Jeppesen, N., Jensen, B. B., Mellemgaard, A., Rytter, C. & Langer, Seppo W., 2008, In: Journal of Thoracic Oncology. 3, 8, p. 902-906 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topotecan and cisplatin in combination with concurrent twice-daily chemoradiation in limited disease small cell lung cancer-a Danish Oncological Lung Cancer Group (DOLG) phase II trial
Sorensen, M., Lassen, Ulrik Niels, Palshof, T., Jensen, B. B., Johansen, J., Jensen, P. B. & Langer, S. W., 2008, In: Lung Cancer. 60, 2, p. 252-258 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topotecan and cisplatin in combination with concurrent twice-daily chemoradiation in limited disease small cell lung cancer-a Danish Oncological Lung Cancer Group (DOLG) phase II trial
Sorensen, M., Lassen, Ulrik Niels, Palshof, T., Jensen, B. B., Johansen, J., Jensen, P. B. & Langer, Seppo W., May 2008, In: Lung Cancer. 60, 2, p. 252-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase II study of a 3-day schedule with topotecan and cisplatin in patients with previously untreated small cell lung cancer and extensive disease
Sorensen, M., Lassen, Ulrik Niels, Jensen, P. B., Østerlind, K., Jeppesen, N., Jensen, B. B., Mellemgaard, A., Rytter, C. & Langer, Seppo W., Aug 2008, In: Journal of Thoracic Oncology. 3, 8, p. 902-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Phase I dose escalation, pharmacokinetic and pharmacodynamic study of naptumomab estafenatox alone in patients with advanced cancer and with docetaxel in patients with advanced non-small-cell lung cancer
Borghaei, H., Alpaugh, K., Hedlund, G., Forsberg, G., Langer, C., Rogatko, A., Hawkins, R., Dueland, S., Lassen, Ulrik Niels & Cohen, R. B., 2009, In: Journal of Clinical Oncology. 27, 25, p. 4116-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preoperative staging of lung cancer with combined PET-CT
Fischer, B., Lassen, U., Mortensen, J., Larsen, S., Loft, A., Bertelsen, A., Ravn, J., Clementsen, P., Høgholm, A., Larsen, K., Rasmussen, T., Keiding, S., Dirksen, A., Gerke, O., Skov, B., Steffensen, I., Hansen, H., Vilmann, P., Jacobsen, G., Backer, V. & 5 others, , 2009, In: New England Journal of Medicine. 361, 1, p. 32-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe skin lesions in patients with glioblastoma multiforme treated with a combination of cetuximab, bevacizumab, and irinotecan
Sorensen, M., Bernhardtsen, T. G., Hasselbalch, B., Poulsen, H. S. & Lassen, Ulrik Niels, 2009, In: European Journal of Clinical & Medical Oncology. 1, 2, p. 1-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Comparison of Endoscopic Ultrasound Guided Biopsy and Positron Emission Tomography with Integrated Computed Tomography in Lung Cancer Staging
Larsen, S. S., Vilmann, Peter, Krasnik, K., Dirksen, A., Clementsen, P., Skov, B. G., Jacobsen, G. K., Lassen, Ulrik Niels, Eigtved, A., Berthelsen, A. K., Mortensen, J. & Højgaard, Liselotte, Jan 2009, In: Current Health Sciences Journal. 35, 1, p. 5-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Markers of angiogenesis and epidermal growth factor receptor signalling in patients with pancreatic and gastroesophageal junction cancer
Rohrberg, K. S., Skov, B. G., Lassen, Ulrik Niels, Christensen, I. J., Høyer-Hansen, G., Buysschaert, I. & Pappot, Helle, 1 Jan 2010, In: Cancer Biomarkers. 7, 3, p. 141-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial
Hasselbalch, B., Lassen, Ulrik Niels, Hansen, S., Holmberg, M., Sørensen, M., Kosteljanetz, M., Broholm, H., Stockhausen, M. & Poulsen, H. S., May 2010, In: Neuro-Oncology. 12, 5, p. 508-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial
Hasselbalch, B., Lassen, Ulrik Niels, Hansen, S., Holmberg, M., Sørensen, M., Kosteljanetz, M., Broholm, H., Stockhausen, M. & Poulsen, H. S., 1 May 2010, In: Neuro-Oncology. 12, 5, p. 508-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours
Lassen, Ulrik Niels, Molife, L. R., Sorensen, J. M., Engelholm, S., Vidal, L., Sinha, R., Penson, R. T., Buhl-Jensen, P., Crowley, E., Tjornelund, J., Knoblauch, P., de Bono, J. S. & Buhl-Jensen, P., 29 Jun 2010, In: B J C. 103, 1, p. 12-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prospective evaluation of angiogenic, hypoxic and EGFR-related biomarkers in recurrent glioblastoma multiforme treated with cetuximab, bevacizumab and irinotecan
Hasselbalch, B., Eriksen, J. G., Broholm, H., Christensen, I. J., Grunnet, K., Horsman, M. R., Poulsen, H. S., Stockhausen, M. & Lassen, Ulrik Niels, Aug 2010, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 118, 8, p. 585-94 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prospective evaluation of angiogenic, hypoxic and EGFR-related biomarkers in recurrent glioblastoma multiforme treated with cetuximab, bevacizumab and irinotecan
Hasselbalch, B., Eriksen, J. G., Broholm, H., Christensen, I. J., Grunnet, K., Horsman, M. R., Poulsen, H. S., Stockhausen, M. & Lassen, Ulrik Niels, 1 Aug 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 8, p. 585-94 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cetuximab insufficiently inhibits glioma cell growth due to persistent EGFR downstream signaling
Hasselbalch, B., Lassen, Ulrik Niels, Poulsen, H. S. & Stockhausen, M., 1 Oct 2010, In: Cancer Investigation. 28, 8, p. 775-87 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
PET-CT in preoperative staging of lung cancer
Fischer, Barbara Malene Bjerregaard, Lassen, Ulrik Niels & Højgaard, Liselotte, 10 Mar 2011, In: New England Journal of Medicine. 364, 10, p. 980-1 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Phase I-II dose escalation study of fixed-dose rate gemcitabine, oxaliplatin and capecitabine every two weeks in advanced cholangiocarcinomas
Lassen, Ulrik Niels, Jensen, L. H., Sorensen, M., Rohrberg, K. S., Ujmajuridze, Z. & Jakobsen, A., 1 Apr 2011, In: Acta Oncologica. 50, 3, p. 448-54 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Irinotecan and bevacizumab in recurrent glioblastoma multiforme
Jakobsen, J. N., Hasselbalch, B., Stockhausen, M., Lassen, Ulrik Niels & Poulsen, H. S., 1 Apr 2011, In: Expert Opinion on Pharmacotherapy. 12, 5, p. 825-33 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multimodality approach to mediastinal staging in non-small cell lung cancer. Faults and benefits of PET-CT: a randomised trial
Fischer, B. M., Mortensen, Jann, Hansen, H., Vilmann, Peter, Larsen, S., Loft, A., Bertelsen, A., Ravn, J., Clementsen, P., Høegholm, A., Larsen, K. R., Dirksen, A., Skov, B. G., Krasnik, M., Højgaard, Liselotte, Lassen, Ulrik Niels, Larsen, S. S., Jakobsen, A. L. & Berthelsen, A. K., 1 Apr 2011, In: Thorax. 66, 4, p. 294-300 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preoperative staging of lung cancer with PET/CT: cost-effectiveness evaluation alongside a randomized controlled trial
Søgaard, R., Fischer, Barbara Malene Bjerregaard, Mortensen, Jann, Højgaard, Liselotte & Lassen, Ulrik Niels, May 2011, In: European Journal of Nuclear Medicine and Molecular Imaging. 38, 5, p. 802-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Phase II trial of erlotinib and bevacizumab in patients with advanced upper gastrointestinal cancers
Rohrberg, K. S., Olesen, R. K., Pfeiffer, P., Ladekarl, M., Pappot, Helle, Christensen, I. J., Høyer-Hansen, G., Sørensen, M., Skov, B. G., Buysschaert, I., Carmeliet, P. & Lassen, Ulrik Niels, Feb 2012, In: Acta oncologica (Stockholm, Sweden). 51, 2, p. 234-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phase I, dose-escalation study of TB-403, a monoclonal antibody directed against PlGF, in patients with advanced solid tumours
Lassen, Ulrik Niels, Nielsen, Dorte Lisbet, Sørensen, M., Winstedt, L., Niskanen, T., Stenberg, Y., Pakola, S., Stassen, J. & Glazer, S., 14 Feb 2012, In: B J C. 106, 4, p. 678-84 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase II activity of belinostat (PXD-101), carboplatin, and paclitaxel in women with previously treated ovarian cancer
Dizon, D. S., Damstrup, L., Finkler, N. J., Lassen, Ulrik Niels, Celano, P., Glasspool, R., Crowley, E., Lichenstein, H. S., Knoblach, P. & Penson, R. T., Jul 2012, In: International Journal of Gynecological Cancer. 22, 6, p. 979-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phase I study of concurrent chemoradiotherapy and cetuximab for locally advanced esophageal cancer
Holländer, C., Baeksgaard, L., Sorensen, M., Albertsson, P., Damstrup, L. & Lassen, Ulrik Niels, Sep 2012, In: Anticancer Research. 32, 9, p. 4019-23 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Pharmacokinetics and tolerability of cediranib, a potent VEGF signalling inhibitor, in cancer patients with hepatic impairment
van Herpen, C. M. L., Lassen, Ulrik Niels, Desar, I. M. E., Brown, K. H., Marotti, M. & de Jonge, M. J. A., 2013, In: Anti-Cancer Drugs. 24, 2, p. 204-11 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase I evaluation of the effects of ketoconazole and rifampicin on cediranib pharmacokinetics in patients with solid tumours
Lassen, Ulrik Niels, Miller, W. H., Hotte, S., Evans, T. R. J., Kollmansberger, C., Adamson, D., Nielsen, Dorte Lisbet, Spicer, J., Chen, E., Meyer, T., Brown, K., Rafi, R. & Sawyer, M. B., 2013, In: Cancer Chemotherapy and Pharmacology. 71, 2, p. 543-549 7 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Phase II study of bevacizumab and temsirolimus combination therapy for recurrent glioblastoma multiforme
Lassen, Ulrik Niels, Sorensen, M., Gaziel, T. B., Hasselbalch, B. & Poulsen, H. S., 2013, In: Anticancer Research. 33, 4, p. 1657-1660 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase II trial of temsirolimus alone and in combination with irinotecan for KRAS mutant metastatic colorectal cancer: Outcome and results of KRAS mutational analysis in plasma
Spindler, K. G., Sørensen, M., Pallisgaard, N., Andersen, R., Havelund, B. M., Ploen, J., Lassen, Ulrik Niels & Jakobsen, L. A., 2013, In: Acta Oncologica. 52, 5, p. 963-970 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Optimality of Different Strategies for Supplemental Staging of Non–Small-Cell Lung Cancer: A Health Economic Decision Analysis
Søgaard, R., Fischer, Barbara Malene Bjerregaard, Mortensen, Jann, Rasmussen, T. R. & Lassen, Ulrik Niels, 2013, In: Value in Health. 16, 1, p. 57-65 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase II study of bevacizumab and temsirolimus combination therapy for recurrent glioblastoma multiforme
Lassen, Ulrik Niels, Sorensen, M., Gaziel, T. B., Hasselbalch, B. & Poulsen, H. S., Apr 2013, In: Anticancer Research. 33, 4, p. 1657-60 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Copenhagen prospective personalized oncology (CoPPO): Sequencing and array-based pipeline for selection of patients to phase 1 studies
Tuxen, I. E. V., Santoni Rugiu, Eric, Joenson, L., Vikesaa, J., Mau-Soerensen, M., Nielsen, Finn Cilius & Lassen, Ulrik Niels, 2014, In: Journal of Clinical Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomet og kræftsygdommene
Nielsen, Finn Cilius & Lassen, Ulrik Niels, 2014, In: Ugeskrift for Laeger. 176, 5 p., V07140419.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Use of Longitudinal 18F-FET MicroPET Imaging to Evaluate Response to Irinotecan in Orthotopic Human Glioblastoma Multiforme Xenografts
Nedergaard, M. K., Kristoffersen, K., Michaelsen, Signe Regner, Madsen, J., Poulsen, H. S., Stockhausen, M., Lassen, Ulrik Niels & Kjær, Andreas, 2014, In: PloS one. 9, 6, p. 1-10 10 p., e100009.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of bevacizumab treatment on survival and quality of life in newly diagnosed glioblastoma patients
Poulsen, H. S., Urup, T., Michaelsen, Signe Regner, Staberg, M., Villingshøj, M. & Lassen, Ulrik Niels, 2014, In: Cancer Management and Research. 6, p. 373-387 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Neoadjuvant bevacizumab and irinotecan versus bevacizumab and temozolomide followed by concomitant chemoradiotherapy in newly diagnosed glioblastoma multiforme: A randomized phase II study
Hofland, K. F., Hansen, S., Sorensen, M., Engelholm, S., Schultz, H. P., Muhic, A., Grunnet, K., Ask, A., Costa, J. C., Kristiansen, C., Thomsen, C., Poulsen, H. S. & Lassen, Ulrik Niels, Jul 2014, In: Acta Oncologica. 53, 7, p. 939-944 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Personalized oncology: genomic screening in phase 1
Tuxen, I. V., Jønson, L., Santoni Rugiu, Eric, Hasselby, J. P., Nielsen, Finn Cilius & Lassen, Ulrik Niels, Aug 2014, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 122, 8, p. 723-733 11 p.Research output: Contribution to journal › Review › Research › peer-review
- 2015
- Published
18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma
Nedergaard, M. K., Michaelsen, Signe Regner, Urup, T., Broholm, H., El Ali, Henrik H., Poulsen, H. S., Stockhausen, M., Kjær, Andreas & Lassen, Ulrik Niels, 2015, In: P L o S One. 10, 2, p. 1-16 16 p., e0115315.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phase I monotherapy study of RG7212, a first-in-class monoclonal antibody targeting TWEAK signaling in patients with advanced cancers
Lassen, Ulrik Niels, Meulendijks, D., Siu, L. L., Karanikas, V., Mau-Sorensen, M., Schellens, J. H. M., Jonker, D. J., Hansen, A. R., Simcox, M. E., Schostack, K. J., Bottino, D., Zhong, H., Roessler, M., Vega-Harring, S. M., Jarutat, T., Geho, D., Wang, K., DeMario, M. & Goss, G. D., 15 Jan 2015, In: Clinical Cancer Research. 21, 2, p. 258-66 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
A phase I trial of intravenous catumaxomab: a bispecific monoclonal antibody targeting EpCAM and the T cell coreceptor CD3
Mau-Sørensen, M., Dittrich, C., Dienstmann, R., Lassen, Ulrik Niels, Büchler, W., Martinius, H. & Tabernero, J., May 2015, In: Cancer Chemotherapy and Pharmacology. 75, 5, p. 1065-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Decline in CA19-9 during chemotherapy predicts survival in four independent cohorts of patients with inoperable bile duct cancer
Grunnet, M., Christensen, I. J., Lassen, Ulrik Niels, Jensen, L. H., Lydolph, M., Knox, J. J., McNamara, M. G., Jitlal, M., Wasan, H., Bridgewater, J., Valle, J. W. & Mau-Sørensen, M., Jul 2015, In: European journal of cancer (Oxford, England : 1990). 51, 11, p. 1381-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase 1 dose-escalation study of the antiplacental growth factor monoclonal antibody RO5323441 combined with bevacizumab in patients with recurrent glioblastoma
Lassen, Ulrik Niels, Chinot, O. L., McBain, C., Mau-Sørensen, M., Larsen, V. A., Barrie, M., Roth, P., Krieter, O., Wang, K., Habben, K., Tessier, J., Lahr, A. & Weller, M., Jul 2015, In: Neuro-Oncology. 17, 7, p. 1007-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma
Lokhorst, H. M., Plesner, T., Laubach, J. P., Nahi, H., Gimsing, P., Hansson, M., Minnema, M. C., Lassen, U., Krejcik, J., Palumbo, A., van de Donk, N. W. C. J., Ahmadi, T., Khan, I., Uhlar, C. M., Wang, J., Sasser, A. K., Losic, N., Lisby, S., Basse, L., Brun, N. & 1 others, , 24 Sep 2015, In: New England Journal of Medicine. 373, 13, p. 1207-19 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of bevacizumab on vestibular schwannoma tumour size and hearing in patients with neurofibromatosis type 2
Alanin, M. C., Klausen, C., Cayé-Thomasen, Per, Thomsen, C., Fugleholm, K., Poulsgaard, L., Lassen, Ulrik Niels, Mau-Sorensen, M. & Hofland, K. F., Dec 2015, In: European Archives of Oto-Rhino-Laryngology. 272, 12, p. 3627-3633 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Actionable targets in recurrent bile duct and pancreatic cancer in a prospective cohort of patients evaluated by whole exome sequencing and SNP array analysis
Tuxen, I. E. V., Mau-Sørensen, M., Yde, C. W., Jønson, L., Oestrup, O., Hasselby, Jane Preuss, Santoni Rugiu, Eric, Lassen, Ulrik Niels & Nielsen, Finn Cilius, 2016, In: Journal of Clinical Oncology. 34, 15, Suppl., 1 p., e23256.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Copenhagen prospective personalized oncology (CoPPO): Genomic profiling to select patients for phase 1 trials
Tuxen, I. V., Yde, C. W., Mau-Sorensen, M., Santoni Rugiu, Eric, Lassen, Ulrik Niels & Nielsen, Finn Cilius, 2016, In: Annals of Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and validation of a prognostic model for recurrent glioblastoma patients treated with bevacizumab and irinotecan
Urup, T., Dahlrot, R. H., Grunnet, K., Christensen, I. J., Michaelsen, Signe Regner, Toft, A., Larsen, V. A., Broholm, H., Kosteljanetz, M., Hansen, S., Poulsen, H. S. & Lassen, Ulrik Niels, 2016, In: Acta Oncologica. 55, 4, p. 418-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of mutant BRAF V600E in free circulating DNA (fcDNA) of non-melanoma cancer patients (pts) in response to treatment with BRAF and MEK/EGFR inhibitors
Mau-Sørensen, M., Ahlborn, L. B., Jønson, L., Oestrup, O., Hasselby, Jane Preuss, Santoni Rugiu, Eric, Nielsen, Finn Cilius, Lassen, Ulrik Niels & Yde, C. W., 2016, In: Journal of Clinical Oncology. 34, 15 (Suppl. S), 11531.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Effect of bevacizumab on intracranial meningiomas in patients with neurofibromatosis type 2: a retrospective case series
Alanin, M. C., Klausen, C., Cayé-Thomasen, Per, Thomsen, C., Fugleholm, Kåre, Poulsgaard, L., Lassen, Ulrik Niels, Mau-Sørensen, M. & Hofland, K. F., 2016, In: International Journal of Neuroscience. 126, 11, p. 1002-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma
Persson, M., Nedergaard, M. K., Brandt-Larsen, M., Skovgaard, D., Jørgensen, Jesper Tranekjær, Michaelsen, Signe Regner, Madsen, J., Lassen, Ulrik Niels, Poulsen, H. S. & Kjær, Andreas, Feb 2016, In: Journal of Nuclear Medicine. 57, 2, p. 272-278 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors
Meulendijks, D., Lassen, Ulrik Niels, Siu, L. L., Huitema, A. D. R., Karanikas, V., Mau-Sørensen, M., Jonker, D. J., Hansen, A. R., Simcox, M. E., Schostack, K. J., Bottino, D., Zhong, H., Roessler, M., Vega-Harring, S. M., Jarutat, T., Geho, D., Wang, K., DeMario, M., Goss, G. D. & Schellens, J. H. M., 15 Feb 2016, In: Clinical Cancer Research. 22, 4, p. 858-67 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors
Meulendijks, D., Jacob, W., Martinez-Garcia, M., Taus, A., Lolkema, M. P., Voest, E. E., Langenberg, M. H. G., Fleitas Kanonnikoff, T., Cervantes, A., De Jonge, M. J., Sleijfer, S., Mau-Sørensen, M., Thomas, M., Ceppi, M., Meneses-Lorente, G., James, I., Adessi, C., Michielin, F., Abiraj, K., Bossenmaier, B. & 3 others, , 15 Feb 2016, In: Clinical Cancer Research. 22, 4, p. 877-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of (18)F-FET and (18)F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma
Nedergaard, M. K., Michaelsen, Signe Regner, Perryman, L., Erler, Janine, Poulsen, H. S., Stockhausen, M., Lassen, Ulrik Niels & Kjær, Andreas, Mar 2016, In: Nuclear Medicine and Biology. 43, 3, p. 198-205 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-Man Dose-Escalation Study of the Selective BRAF Inhibitor RG7256 in Patients with BRAF V600-Mutated Advanced Solid Tumors
Dienstmann, R., Lassen, Ulrik Niels, Cebon, J., Desai, J., Brown, M. P., Evers, S., Su, F., Zhang, W., Boisserie, F., Lestini, B., Schostack, K., Meresse, V. & Tabernero, J., Apr 2016, In: Targeted Oncology. 11, 2, p. 149-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients
Urup, T., Michaelsen, Signe Regner, Olsen, L. R., Toft, A., Christensen, I. J., Grunnet, K., Winther, Ole, Broholm, H., Kosteljanetz, M., Issazadeh-Navikas, Shohreh, Poulsen, H. S. & Lassen, Ulrik Niels, Oct 2016, In: Molecular Oncology. 10, 8, p. 1160-1168Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma
Plesner, T., Arkenau, H-T., Gimsing, P., Krejcik, J., Lemech, C., Minnema, M. C., Lassen, U. N., Laubach, J. P., Palumbo, A., Lisby, S., Basse, L., Wang, J., Sasser, A. K., Guckert, M. E., de Boer, C., Khokhar, N. Z., Yeh, H., Clemens, P. L., Ahmadi, T., Lokhorst, H. M. & 1 others, , Oct 2016, In: Blood. 128, 14, p. 1821-1828Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors
Abdul Razak, A. R., Mau-Sørensen, M., Gabrail, N. Y., Gerecitano, J. F., Shields, A. F., Unger, T. J., Saint-Martin, J. R., Carlson, R., Landesman, Y., McCauley, D., Rashal, T., Lassen, Ulrik Niels, Kim, R., Stayner, L., Mirza, M. R., Kauffman, M., Shacham, S. & Mahipal, A., Dec 2016, In: Journal of Clinical Oncology. 34, 34, p. 4142-4150 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hallmarks of glioblastoma: a systematic review
Nørøxe, D. S., Poulsen, H. S. & Lassen, Ulrik Niels, Dec 2016, In: E S M O Open. 1, 6, 9 p., e000144.Research output: Contribution to journal › Review › Research › peer-review
- 2017
- Published
Concordance of mutation detection in circulating tumor DNA in early clinical trials using different blood collection protocols
Ahlborn, L. B., Madsen, M., Jonson, L., Nielsen, Finn Cilius, Lassen, Ulrik Niels, Yde, C. W. & Mau-Sorensen, M., 2017, In: Clinical Laboratory. 63, 10, p. 1755-1759Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer
Jacobsen, K., Bertran-Alamillo, J., Molina, M. A., Teixidó, C., Karachaliou, N., Pedersen, M. H., Castellví, J., Garzón, M., Codony-Servat, C., Codony-Servat, J., Giménez-Capitán, A., Drozdowskyj, A., Viteri, S., Larsen, M. R., Lassen, Ulrik Niels, Felip, E., Bivona, T. G., Ditzel, H. J. & Rosell, R., 2017, In: Nature Communications. 8, 14 p., 410.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity
Meulendijks, D., Jacob, W., Voest, E. E., Mau-Sorensen, M., Martinez-Garcia, M., Taus, A., Fleitas, T., Cervantes, A., Lolkema, M. P., Langenberg, M. H. G., De Jonge, M. J., Sleijfer, S., Han, J-Y., Calles, A., Felip, E., Kim, S-W., Schellens, J. H. M., Wilson, S., Thomas, M., Ceppi, M. & 11 others, , 2017, In: Clinical Cancer Research. 23, 18, p. 5406-5415Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients
Urup, T., Staunstrup, L. M., Michaelsen, Signe Regner, Vitting-Seerup, K., Bennedbæk, M., Toft, A., Olsen, L. R., Jønson, L., Issazadeh-Navikas, Shohreh, Broholm, H., Hamerlik, P., Poulsen, H. S. & Lassen, Ulrik Niels, 18 Apr 2017, In: BMC Cancer. 17, 10 p., 278.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical trial allocation in multinational pharmaceutical companies: a qualitative study on influential factors
Dombernowsky, T., Hædersdal, Merete, Lassen, Ulrik Niels & Thomsen, Simon Francis, Jun 2017, In: Pharmacology Research & Perspectives. 5, 3, 9 p., e00317.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of copy number alterations in cell-free tumor DNA from plasma
Østrup, O., Ahlborn, L. B., Lassen, Ulrik Niels, Mau-Sørensen, M. & Nielsen, Finn Cilius, Jun 2017, In: BBA Clinical. 7, p. 120-126 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development in the number of clinical trial applications in Western Europe from 2007 to 2015: retrospective study of data from national competent authorities
Dombernowsky, T., Hædersdal, Merete, Lassen, Ulrik Niels & Thomsen, Simon Francis, Jul 2017, In: B M J Open. 7, 7, 10 p., e015579.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
A drug-drug interaction study to assess the effect of the CYP1A2 inhibitor fluvoxamine on the pharmacokinetics of dovitinib (TKI258) in patients with advanced solid tumors
de Weger, V. A., Goel, S., von Moos, R., Schellens, J. H. M., Mach, N., Tan, E., Anand, S., Scott, J. W. & Lassen, Ulrik Niels, 2018, In: Cancer Chemotherapy and Pharmacology. 81, 1, p. 73-80 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A systematic review of targeted agents for non-small cell lung cancer
Vestergaard, H. H., Christensen, M. R. & Lassen, Ulrik Niels, 2018, In: Acta Oncologica. 57, 2, p. 176-186 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan
Toft, A., Urup, T., Christensen, I. J., Michaelsen, Signe Regner, Lukram, B., Grunnet, K., Kosteljanetz, M., Larsen, V. A., Lassen, Ulrik Niels, Broholm, H. & Poulsen, H. S., 2018, In: Cancer Investigation. 36, 2, p. 165-174 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors
Ahlborn, L. B., Tuxen, I. V., Mouliere, F., Kinalis, S., Schmidt, A. Y., Rohrberg, K. S., Santoni Rugiu, Eric, Nielsen, Finn Cilius, Lassen, Ulrik Niels, Yde, C. W., Oestrup, O. & Mau-Sorensen, M., 2018, In: OncoTarget. 9, 66, p. 32570-32579Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children
Drilon, A., Laetsch, T. W., Kummar, S., DuBois, S. G., Lassen, U. N., Demetri, G. D., Nathenson, M., Doebele, R. C., Farago, A. F., Pappo, A. S., Turpin, B., Dowlati, A., Brose, M. S., Mascarenhas, L., Federman, N., Berlin, J., El-Deiry, W. S., Baik, C., Deeken, J., Boni, V. & 18 others, , 2018, In: The New England Journal of Medicine. 378, 8, p. 731-739Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer
Massard, C., Azaro, A., Soria, J., Lassen, Ulrik Niels, Le Tourneau, C., Sarker, D., Smith, C., Ohnmacht, U., Oakley, G., Patel, B. K. R., Yuen, E. S. M., Benhadji, K. A. & Rodon, J., 2018, In: Annals of oncology : official journal of the European Society for Medical Oncology. 29, 9, p. 1911-1917 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular profiling of short-term and long-term surviving patients identifies CD34 mRNA level as prognostic for glioblastoma survival
Michaelsen, Signe Regner, Urup, T., Olsen, L. R., Broholm, H., Lassen, Ulrik Niels & Poulsen, H. S., 2018, In: Journal of Neuro-Oncology. 137, 3, p. 533-542 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational landscape assessed in tumor tissue and cell-free DNA during neratinib treatment of patients with HER2 mutated solid tumors
Spanggaard, I., Oestrup, O., Bertelsen, B., Rohrberg, K. S., de Schmidt, A. Y., Tuxen, I. V., Ahlborn, L. B., Hasselby, Jane Preuss, Santoni Rugiu, Eric, Marvig, R. L., Lassen, Ulrik Niels, Nielsen, Finn Cilius, Yde, C. W. & Mau-Sørensen, M., 2018, In: European Journal of Cancer. 103, Suppl. 1, p. E142-E143 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Outcome of Bevacizumab Therapy in Patients with Recurrent Glioblastoma Treated with Angiotensin System Inhibitors
Johansen, M. D., Urup, T., Holst, C. B., Christensen, I. J., Grunnet, K., Lassen, Ulrik Niels, Friis, S. & Poulsen, H. S., 2018, In: Cancer Investigation. 36, 9-10, p. 512-519 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phase Ib study evaluating safety and clinical activity of the anti-HER3 antibody lumretuzumab combined with the anti-HER2 antibody pertuzumab and paclitaxel in HER3-positive, HER2-low metastatic breast cancer
Schneeweiss, A., Park-Simon, T. W., Albanell, J., Lassen, U., Cortés, J., Dieras, V., May, M., Schindler, C., Marmé, F., Cejalvo, J. M., Martinez-Garcia, M., Gonzalez, I., Lopez-Martin, J., Welt, A., Levy, C., Joly, F., Michielin, F., Jacob, W., Adessi, C., Moisan, A. & 7 others, , 2018, In: Investigational New Drugs. 36, 5, p. 848-859 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRK Inhibition: A New Tumor-Agnostic Treatment Strategy
Kummar, S. & Lassen, Ulrik Niels, 2018, In: Targeted Oncology. 13, 5, p. 545-556Research output: Contribution to journal › Review › Research › peer-review
- Published
VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance
Michaelsen, Signe Regner, Staberg, M., Pedersen, H., Jensen, K. E., Majewski, W., Broholm, H., Nedergaard, M. K., Meulengracht, C., Urup, T., Villingshøj, M., Lukacova, S., Skjøth-Rasmussen, J., Brennum, J., Kjær, Andreas, Lassen, Ulrik Niels, Stockhausen, M., Poulsen, H. S. & Hamerlik, P., 2018, In: Neuro-Oncology. 20, 11, p. 1462-1474Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient information in phase 1 trials: A systematic review
Gad, K. T., Lassen, Ulrik Niels, Mau-Søerensen, M., Høybye, M. T. & Johansen, Christoffer, Mar 2018, In: Psycho-Oncology. 27, 3, p. 768-780Research output: Contribution to journal › Review › Research › peer-review
- 2019
- Published
A phase I study of the PARP inhibitor niraparib in combination with bevacizumab in platinum-sensitive epithelial ovarian cancer: NSGO AVANOVA1/ENGOT-OV24
Mirza, M. R., Bergmann, T. K., Mau-Sørensen, M., Christensen, R. D., Åvall-Lundqvist, E., Birrer, M. J., Jørgensen, M., Roed, H., Malander, S., Nielsen, F., Lassen, Ulrik Niels, Brøsen, K., Bjørge, L. & Mäenpää, J., 2019, In: Cancer Chemotherapy and Pharmacology. 84, 4, p. 791-798 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phase Ib/II study of HER3-targeting lumretuzumab in combination with carboplatin and paclitaxel as first-line treatment in patients with advanced or metastatic squamous non-small cell lung cancer
Cejalvo, J. M., Jacob, W., Fleitas Kanonnikoff, T., Felip, E., Navarro Mendivil, A., Martinez Garcia, M., Taus Garcia, A., Leighl, N., Lassen, Ulrik Niels, Mau-Soerensen, M., Adessi, C., Michielin, F., James, I., Ceppi, M., Hasmann, M., Weisser, M. & Cervantes, A., 2019, In: ESMO Open. 4, 4, 7 p., e000532.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4952653
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Clinical trial allocation in multinational pharmaceutical companies: a qualitative study on influential factors
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Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients
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Hallmarks of glioblastoma: a systematic review
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