Kirsten Grønbæk

Kirsten Grønbæk

Clinical Professor

Member of:

  • Internal Medicine: Haematology


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  1. Published

    "Randomized phase II study of azacitidine ± lenalidomide in higher-risk myelodysplastic syndromes and acute myeloid leukemia with a karyotype including Del(5q)"

    Rasmussen, B., Gohring, G., Bernard, E., Nilsson, L., Tobiasson, M., Jadersten, M., Garelius, H., Dybedal, I., Gronbaek, K., Ejerblad, E., Lorenz, F., Flogegard, M., Marcher, C. W., oster Fernstrom, A., Cavelier, L., Papaemmanuil, E., Ebeling, F., Kittang, A. O., Norgaard, J. M., Saft, L. & 2 others, Mollgard, L. & Hellstrom-Lindberg, E., May 2022, In: Leukemia. 36, 5, p. 1436-1439 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  2. Published

    10-year nationwide trends in incidence, treatment patterns, and mortality of patients with myelodysplastic syndromes in Denmark

    Lauritsen, T. B., Nørgaard, J. M., Dalton, Susanne Oksbjerg, Grønbæk, Kirsten, El-Galaly, T. C. & Østgård, L. S. G., 2023, In: Leukemia Research. 128, 10 p., 107056.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau

    Eskelund, C. W., Kolstad, A., Jerkeman, M., Räty, R., Laurell, A., Eloranta, S., Smedby, K. E., Husby, S., Pedersen, L. B., Andersen, N. S., Eriksson, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J. & 7 others, Karjalainen-Lindsberg, M., Workman, C. T., Garde, C., Elonen, E., Brown, Peter de Nully, Grønbæk, Kirsten & Geisler, C. H., Nov 2016, In: British Journal of Haematology. 175, 3, p. 410-418 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    5-Azacytidine treatment sensitizes tumor cells to T-cell mediated cytotoxicity and modulates NK cells in patients with myeloid malignancies

    Gang, A. O., Frøsig, T. M., Brimnes, M. K., Lyngaa, R., Treppendahl, M. B., Grønbæk, Kirsten, Dufva, I. H., Straten, P. T. & Hadrup, S. R., 2014, In: Blood Cancer Journal. 4, 3, p. 1-9 9 p., e197.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy

    Munch-Petersen, H. D., Asmar, F., Dimopoulos, K., Areškevičiūtė, A., Brown, Peter de Nully, Girkov, M. S., Pedersen, A., Sjö, Lene Dissing, Heegaard, Steffen, Broholm, H., Kristensen, L. S., Ralfkiaer, E. & Grønbæk, Kirsten, 22 Apr 2016, In: Acta Neuropathologica Communications. 4, 13 p., 40.

    Research output: Contribution to journal › Journal article › Research

  6. Published

    TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

    Eskelund, C. W., Dahl, C., Hansen, Jakob Werner, Westman, M., Kolstad, A., Pedersen, L. B., Montano-Almendras, C. P., Husby, Simon, Freiburghaus, C., Ek, S., Vestergaard, Anja Holm, Niemann, Carsten, Raty, R., Brown, Peter de Nully, Geisler, C. H., Andersen, M. K., Guldberg, P., Jerkeman, M. & Grønbæk, Kirsten, 2017, In: Blood. 130, 17, p. 1903-1910 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

    Gingold, H., Tehler, D., Christoffersen, N. R., Nielsen, M. M., Asmar, F., Kooistra, S. M., Christophersen, N. S., Christensen, L. L., Borre, M., Sørensen, K. D., Andersen, L. D., Andersen, C. L., Hulleman, E., Wurdinger, T., Ralfkiær, E., Helin, K., Grønbæk, K., Orntoft, T., Waszak, S. M., Dahan, O. & 3 others, Pedersen, J. S., Lund, Anders H. & Pilpel, Y., 11 Sep 2014, In: Cell. 158, 6, p. 1281-92 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A Lack of Diversity, Equity, and Inclusion in Clinical Research Has Direct Impact on Patient Care

    El-Galaly, T. C., Gaidzik, V. I., Gaman, M. A., Antic, D., Okosun, J., Copland, M., Sexl, V., Fielding, A. K., Doeswijk, R., Parker, H., Dreyling, M., Döhner, K., Almeida, A. M., Macintyre, E., Gribben, J. G. & Grønbæk, Kirsten, 2023, In: HemaSphere. 7, 3, 4 p., e842.

    Research output: Contribution to journal › Editorial › Research

  9. Published

    A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia

    Toft-Petersen, M., Kjeldsen, E., Nederby, L., Grønbæk, Kirsten, Hokland, P. & Roug, A. S., 2014, In: Leukemia Research Reports. 3, 2, p. 94-97 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A novel splice mutation in the TP53 gene associated with Leydig cell tumor and primitive neuroectodermal tumor

    Stecher, C. W., Hasle, H. & Grønbæk, Kirsten, 2008, In: Pediatric Blood & Cancer. 50, 3, p. 701-703 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A predictive model for bone marrow disease in cytopenia based on noninvasive procedures

    Træden, D., Tulstrup, M., Cowland, J. B., Sjö, Lene Dissing, Bøgsted, M., Grønbæk, Kirsten, Andersen, M. K. & Hansen, J. W., 2022, In: Blood advances. 6, 11, p. 3541-3550

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A second update on mapping the human genetic architecture of COVID-19

    Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, Hjalgrim, Henrik, Admin team lead, A. T. L., Admin team member, A. T. M., Analysis team lead, A. T. L., Analysis team member, A. T. M., Data collection lead, D. C. L., Data collection member, D. C. M., Manuscript analysis team lead, M. A. T. L., Manuscript analysis team members: Mendelian randomization, M. A. T. M. M. R., Manuscript analysis team members: methods development, M. A. T. M. M. D., Manuscript analysis team members: phenome-wide association study, M. A. T. M. P. A. S., Manuscript analysis team members: principal component projection, gene prioritization, M. A. T. M. P. C. P. G. P., Project management lead, P. M. L., Scientific communication lead, S. C. L., Scientific communication member, S. C. M., Writing group lead, W. G. L., Writing group member, W. G. M., 23andMe, 2., Adolescent brain and cognitive development study, A. B. A. C. D. S., Analysis group, A. G., Armenia_Covid-19hg, A., Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome, A. O. T. I. O. C. F. I. A. G. F. O. T. S. O. T. C. O. C. I. W. S. A. P. S., Avon Longitudinal Study of Parents and Children (ALSPAC), A. L. S. O. P. A. C. (., BelCovid, B., Biobanque Quebec COVID19, B. Q. C., BioVU, B., Bonn Study of COVID-19 Genetics, B. S. O. C. G., CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank, C. H. C. H. H. G. S. D., Colorado Center for Personalized Medicine—CCPM, C. C. F. P. M., COMRI/Virology Study, C. S., Covid19 Ioannina Biobank, C. I. B., COVID19-Host(a)ge, C., Covid19hg-CL, C., Danish COVID-19 Genomic Consortium, D. C. G. C., Egypt hgCOVID hub, E. H. H., EraCORE, E., FinnGen, F., French hgCOVID, F. H., GCAT. Genomes For Life, G. G. F. L., Genes & Health, G. &. H., Genetic influences on severity of COVID-19 illness in Korea, G. I. O. S. O. C. I. I. K., GenOMICC, G., Genotek COVID-19 study, G. C. S., Helix Exome+ COVID-19 Phenotypes, H. E. C. P., Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population, H. G. F. F. C. S. A. O. I. W. I. P., Host Genetics in COVID Cohorts of Mixed ancestry from Mexico, H. G. I. C. C. O. M. A. F. M., Japan Coronavirus Taskforce, J. C. T., Japan NCGM-COVID19, J. N., Jordan COVID-19 Host Genomics Initiative (JCHGI), J. C. H. G. I. (., Leadership, L., Lung eQTL Consortium, L. E. C., Mass General Brigham—Host Vulnerability to COVID-19, M. G. B. V. T. C., MexGen-COVID, M., Pa-COVID-19, P., Project management group, P. M. G., Project management support, P. M. S., Qatar Genome Program, Q. G. P., SARS-CoV-2 and Host Genome sequencing, S. A. H. G. S., Scientific communication group, S. C. G., Search for Genomic Markers Predicting the Severity of the response to COVID-19, S. F. G. M. P. T. S. O. T. R. T. C., Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE), S. C. T. U. R. O. H. G. O. C. (., The Danish Blood Donor Study, T. D. B. D. S., The Genetic Predisposition to severe COVID-19, T. G. P. T. S. C., Tirschenreuth Study (TiKoco), T. S. (., UCLA Precision Health COVID-19 Host Genomics Biobank, U. P. H. C. H. G. B., UK Biobank, U. B., Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study), V. I. I. R. G. A. S. O. S. I. (. S., Website development, W. D., Writing Group, W. G. & The COVID-19 Host Genetics Initiative, T. C. H. G. I., 2023, In: Nature. 621, 7977, p. E7-E26 23 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  13. Published

    A user's guide to multicolor flow cytometry panels for comprehensive immune profiling

    Holmberg-Thyden, S., Grønbæk, Kirsten, Gang, Anne Ortved, Fassi, Daniel El & Hadrup, S. R., 2021, In: Analytical Biochemistry. 627, 114210.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

    Sommer Kristensen, L., Hansen, Jakob Werner, Kristensen, S. S., Tholstrup, D., Harsløf, L. B. S., Pedersen, Ole Birger Vesterager, Brown, Peter de Nully & Grønbæk, Kirsten, 2016, In: Clinical Epigenetics. 8, 11 p., 95.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Aberrant microRNA expression in multiple myeloma

    Dimopoulos, K., Gimsing, P. & Grønbæk, Kirsten, 2013, In: European Journal of Haematology. 91, 2, p. 95-105 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Activation of a subset of evolutionarily young transposable elements and innate immunity are linked to clinical responses to 5-azacytidine

    Ohtani, H., mxz703, mxz703, Helbo, A. S., Gillberg, Linn, Liu, M., Zhou, W., Ungerstedt, J., Hellström-Lindberg, E., Sun, W., Liang, G., Jones, P. A. & Grønbæk, Kirsten, 2020, In: Cancer Research. 80, 12, p. 2441-2450 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients

    Bliddal, S., Banasik, Karina, Pedersen, Ole Birger Vesterager, Nissen, J., Cantwell, Lisa, Schwinn, M., Tulstrup, Morten Rytter, Westergaard, D., Ullum, H., Brunak, Søren, Tommerup, Niels, Feenstra, B., Geller, F., Ostrowski, Sisse Rye, Grønbæk, Kirsten, Nielsen, Claus Henrik, Nielsen, Susanne Dam & Feldt-Rasmussen, Ulla, 2021, In: Scientific Reports. 11, 13153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Allele-Specific DNA Methylation Detection by Pyrosequencing®

    Sommer Kristensen, L., Johansen, Jens Vilstrup & Grønbæk, Kirsten, 2015, Pyrosequencing: Methods and Protocols. Lehmann, U. & Tost, J. (eds.). Vol. 1315. p. 271-89 19 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  19. Published

    Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

    Treppendahl, M. B., Qiu, X., Søgaard, A., Yang, X., Nandrup-Bus, C., Hother, C., Andersen, M. K., Kjeldsen, L., Möllgård, L., Möllgaard, L., Hellström-Lindberg, E., Jendholm, L. J., Porse, Bo Torben, Jones, P. A., Liang, G. & Grønbæk, Kirsten, 5 Jan 2012, In: Blood. 119, 1, p. 206-16 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelomonocytic Leukemia: Clinical and Molecular Genetic Prognostic Factors in a Nordic Population

    Wedge, E., Hansen, J. W., Dybedal, I., Creignou, M., Ejerblad, E., Lorenz, F., Werlenius, O., Ungerstedt, J., Holm, M. S., Nilsson, L., Kittang, A. O., Antunovic, P., Rohon, P., Andersen, M. K., Papaemmanuil, E., Bernard, E., Jädersten, M., Hellström-Lindberg, E., Grønbæk, K., Ljungman, P. & 1 others, Friis, L. S., 2021, In: Transplantation and Cellular Therapy. 27, 12, p. 991.e1-991.e9

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Analysis of epigenetic modifications of DNA in human cells

    Kristensen, L. S., Treppendahl, M. B. & Grønbæk, Kirsten, 2013, In: Current Protocols in Human Genetics. Suppl. 77, 22 p., Unit20.2.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period

    Hansen, Jakob Werner, Sandholdt, H., Siersma, Volkert Dirk, mxz703, mxz703, Holmberg, S., Bjerrum, O. W., Hasselbalch, Hans Carl, Olivarius, Niels de Fine, Grønbæk, Kirsten & Andersen, Christen Bertel L, Jul 2017, In: American Journal of Hematology. 92, 7, p. E130-E132 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  23. Published

    Angiotensinogen promoter methylation predicts bevacizumab treatment response of patients with recurrent glioblastoma

    Urup, T., Gillberg, Linn, Kaastrup, K., Lü, M. J. S., Michaelsen, Signe Regner, Andrée Larsen, V., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2020, In: Molecular Oncology. 14, 5, p. 964-973

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Angiotensinogen promoter methylation to predict bevacizumab response in recurrent glioblastoma patients

    Urup, T., Gillberg, Linn, Kaastrup, K., Lu, M. S., Michaelsen, Signe Regner, Larsen, V. A., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2019, In: Neuro-Oncology. 21, Supplement 6, p. vi149

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  25. Published

    Arvelig prædisposition til myeloid neoplasi hos voksne

    Nitschke, N. J., Andersen, M. K. & Grønbæk, Kirsten, 2021, In: Ugeskrift for Laeger. 183, 42, V04210346.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 37722667