Oluf Borbye Pedersen
Visiting professor, Clinical Professor
Pedersen Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal
2200 København N.
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal medicine: infection medicine
Internal Medicine: Endocrinology
- 2009
- Published
Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes
Clausen, Tine Dalsgaard, Mathiesen, E. R., Hansen, T., Pedersen, Oluf Borbye, Jensen, D. M., Lauenborg, J., Schmidt, Lone, Damm, Peter, Clausen, T. D., Mathiesen, Elisabeth, Hansen, T., Pedersen, O., Jensen, D., Lauenborg, J., Schmidt, L. & Damm, Peter, 1 Jul 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 7, p. 2464-70 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
Pilgaard, K., Jensen, C., Schou, J., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., Vaag, A., Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L. & 10 others, , 1 Jul 2009, In: Diabetologia. 52, 7, p. 1298-307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common type 2 diabetes risk gene variants associate with gestational diabetes
Lauenborg, J., Grarup, N., Damm, Peter, Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Hansen, T., Lauenborg, J., Grarup, N., Damm, Peter, Borch-Johnsen, K., Jørgensen, T., Pedersen, O. & Hansen, T., 1 Jan 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 1, p. 145-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads
Rose, C. S., Grarup, Niels, Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, T., Banasik, Karina, Faerch, K., Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: Diabetologia. 52, 10, p. 2122-2129 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
Bouatia-Naji, N., Bonnefond, A., Cavalcanti-Proença, C., Sparsø, T., Holmkvist, J., Marchand, M., Delplanque, J., Lobbens, S., Rocheleau, G., Durand, E., De Graeve, F., Chèvre, J-C., Borch-Johnsen, K., Hartikainen, A-L., Ruokonen, A., Tichet, J., Marre, M., Weill, J., Heude, B., Tauber, M. & 21 others, , 2009, In: Nature Genetics. 41, 1, p. 89-94 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults
Rathcke, C. N., Holmkvist, J., Husmoen, L. L. N., Hansen, T., Pedersen, Oluf Borbye, drb459, drb459 & Linneberg, Allan René, 2009, In: PLoS ONE. 4, 7, p. e6106Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bleeding peptic ulcer. Prevalence of Helicobacter pylori and use of nonsteroidal anti-inflammatory drugs/acetylsalicylic acid
Vestergard, A., Bredahl, K., Muckadell, O. B. D., Pedersen, Oluf Borbye & Hansen, J. M., 2009, In: Ugeskrift for læger. 171, 4, p. 235-239 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction
Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, S., Hansen, T., Pedersen, O., Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T. & 6 others, , 2009, In: Diabetologia. 52, 7, p. 1308-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial
Lund, S. S., Tarnow, L., Frandsen, M., Nielsen, B. B., Hansen, B. V., Pedersen, Oluf Borbye, Parving, H. & Vaag, A. A., 2009, In: BMJ. British Medical Journal (International Ed.). 339, p. b4324Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a type 2 diabetes risk model from a panel of serum biomarkers from the Inter99 cohort
Kolberg, J. A., Jørgensen, T., Gerwien, R. W., Hamren, S., McKenna, M. P., Moler, E., Rowe, M. W., Urdea, M. S., Xu, X. M., Hansen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetes Care. 32, 7, p. 1207-12 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes in infants may be treated with sulfonylurea as a replacement for insulin
Lauridsen, M. H., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T. & Hertz, B., 2009, In: Ugeskrift for læger. 171, 23, p. 1923-1924 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary patterns predict changes in two-hour post-oral glucose tolerance test plasma glucose concentrations in middle-aged adults
Lau, C., Toft, U., Tetens, Inge , Carstensen, Bendix, Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Journal of Nutrition. 139, 3, p. 588-593 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men
Zimmermann, E., Kring, S. I. I., Berentzen, T. L., Holst, C., Pers, T. H., Hansen, Torben, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Jess, T., 2009, In: PLoS ONE. 4, 2, p. e4428Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional SOCS1 polymorphisms are associated with variation in obesity in whites
Gylvin, T., Ek, J., Nolsøe, R., Albrechtsen, A., Andersen, G., Bergholdt, R., Brorsson, C., Bang-Berthelsen, C. H., Hansen, T., Karlsen, A. E., Billestrup, N., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 2009, In: Diabetes, Obesity and Metabolism. 11, 3, p. 196-203 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans
Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M-R., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K. & 36 others, , 2009, In: Diabetes. 58, 6, p. 1450-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: The DAMAGE study
Reiling, E., van Vliet-Ostaptchouk, J. V., van 't Riet, E., van Haeften, T. W., Arp, P. A., Hansen, Torben, Kremer, D., Groenewoud, M. J., van Hove, E. C., Romijn, J. A., Smit, J. W. A., Nijpels, G., Heine, R. J., Uitterlinden, A. G., Pedersen, Oluf Borbye, Slagboom, P. E., Maassen, J. A., Hofker, M. H., 't Hart, L. M. & Dekker, J. M., 2009, In: European Journal of Human Genetics. 17, 8, p. 1056-1062 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
Perry, J. R. B., Weedon, M. N., Langenberg, C., Jackson, A. U., Lyssenko, V., Sparsø, T., Thorleifsson, G., Grallert, H., Ferrucci, L., Maggio, M., Paolisso, G., Walker, M., Palmer, C. N. A., Payne, F., Young, E., Herder, C., Narisu, N., Morken, M. A., Bonnycastle, L. L., Owen, K. R. & 38 others, , 2009, In: Human Molecular Genetics. 19, 3, p. 535-44 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits
Bonnefond, A., Vaxillaire, M., Labrune, Y., Lecoeur, C., Chèvre, J-C., Bouatia-Naji, N., Cauchi, S., Balkau, B., Marre, M., Tichet, J., Riveline, J-P., Hadjadj, S., Gallois, Y., Czernichow, S., Hercberg, S., Kaakinen, M., Wiesner, S., Charpentier, G., Lévy-Marchal, C., Elliott, P. & 7 others, , 2009, In: Diabetes. 58, 11, p. 2687-97 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
Rung, J., Cauchi, S., Albrechtsen, A., Shen, L., Rocheleau, G., Cavalcanti-Proença, C., Bacot, F., Balkau, B., Belisle, A., Borch-Johnsen, K., Charpentier, G., Dina, C., Durand, E., Elliott, P., Hadjadj, S., Järvelin, M-R., Laitinen, J., Lauritzen, T., Marre, M., Mazur, A. & 20 others, , 2009, In: Nature Genetics. 41, 10, p. 1110-1115 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
Thorleifsson, G., Walters, G. B., Gudbjartsson, D. F., Steinthorsdottir, V., Sulem, P., Helgadottir, A., Styrkarsdottir, U., Gretarsdottir, S., Thorlacius, S., Jonsdottir, I., Jonsdottir, T., Olafsdottir, E. J., Olafsdottir, G. H., Jonsson, T., Jonsson, F., Borch-Johnsen, K., Hansen, T., Andersen, G., Jørgensen, T., Lauritzen, T. & 15 others, , 2009, In: Nature Genetics. 41, 1, p. 18-24 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IDENTIFICATION OF NOVEL VARIANTS IN THE HEPATOCYTE NUCLEAR FACTOR 1 ALPHA GENE IN SOUTH INDIAN PATIENTS WITH MATURITY ONSET DIABETES OF YOUNG
Radha, V., Ek, J., Anuradha, S., Hansen, T., Pedersen, Oluf Borbye & Mohan, V., 2009, In: Journal of Clinical Endocrinology and Metabolism. 6, p. 1959-65Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel variants in the hepatocyte nuclear factor-1alpha gene in South Indian patients with maturity onset diabetes of young
Radha, V., Ek, J., Anuradha, S., Hansen, T., Pedersen, Oluf Borbye & Mohan, V., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 6, p. 1959-1965 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics
Koutnikova, H., Laakso, M., Lu, L., Combe, R., Paananen, J., Kuulasmaa, T., Kuusisto, J., Häring, H., Hansen, T., Pedersen, Oluf Borbye, Smith, U., Hanefeld, M., Williams, R. W. & Auwerx, J., 2009, In: PLoS Genetics. 5, 8, p. e1000591Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased recovery rates of phosphocreatine and inorganic phosphate after isometric contraction in oxidative muscle fibres and elevated hepatic insulin resistance in homozygous carriers of the A-allele of FTO rs9939609
Grunnet, Louise Groth, Brøns, C., Jacobsen, S., Nilsson, E., Astrup, A., Hansen, T., Pedersen, Oluf Borbye, Poulsen, P., Quistorff, B. & Vaag, A., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 596-602 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention
Meur, G., Simon, A., Harun, N., Virally, M., Dechaume, A., Bonnefond, A., Fetita, S., Tarasov, A. I., Guillausseau, P., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T., Polak, M., Gautier, J., Froguel, P., Rutter, G. A. & Vaxillaire, M., 2009, In: Diabetes. 59, 3, p. 653-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intensified multifactorial treatment of patients with Type 2 diabetes: what can be achieved and does it pay off?
Pedersen, Oluf Borbye, 2009, In: Journal of Diabetes. 1, 2, p. 83-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G >C with circulating glucose levels, interleukin-6 levels, and body mass index.
Huth, C., Illig, T., Herder, C., Gieger, C., Grallert, H., Vollmert, C., Rathmann, W., Hamid, Y., Pedersen, O., Hansen, T., Thorand, B., Meisinger, C., Doring, A., Klopp, N., Gohlke, H., Lieb, W., Hengstenberg, C., Lyssenko, V., Groop, L., Ireland, H. & 16 others, , 2009, In: Annals of Medicine. 41, p. 128-38Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index
Huth, C., Illig, T., Herder, C., Gieger, C., Grallert, H., Vollmert, C., Rathmann, W., Hamid, Y. H., Pedersen, O., Hansen, T., Thorand, B., Meisinger, C., Doring, A., Klopp, N., Gohlke, H., Lieb, W., Hengstenberg, C., Lyssenko, V., Groop, L., Ireland, H. & 16 others, , 2009, In: Annals of Medicine. 41, 2, p. 128-138 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes
Torsvik, J., Johansson, S., Johansen, A., Ek, J., Minton, J., Raeder, H., Ellard, S., Hattersley, A., Pedersen, Oluf Borbye, Hansen, T., Molven, A. & Njølstad, P. R., 2009, In: Human Genetics. 127, 1, p. 55-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult Danes
Gjesing, A. P., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Hansen, T. & Olsen, N. V., 2009, In: PLoS ONE. 4, 9, p. e7206Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Past and current body size affect validity of reported energy intake among middle-aged Danish men
Nielsen, B. M., Nielsen, M. M., Toubro, S., Pedersen, Oluf Borbye, Astrup, A., Sørensen, Thorkild I.A., Jess, T. & Heitmann, B. L., 2009, In: Journal of Nutrition. 139, 12, p. 2337-2343 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes
Kring, S. I. I., Werge, Thomas, Holst, C., Toubro, S., Astrup, A., Hansen, Torben, Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2009, In: PLoS ONE. 4, 8, p. e6696 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictive performance for population models using stochastic differential equations applied on data from an oral glucose tolerance test
Møller, J. B., Overgaard, R. V., Madsen, H., Hansen, T., Pedersen, Oluf Borbye & Ingwersen, S. H., 2009, In: Journal of Pharmacokinetics and Pharmacodynamics. 37, 1, p. 85-98 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictors of future fasting and 2-h post-OGTT plasma glucose levels in middle-aged men and women-the Inter99 study
Faerch, K., Vaag, Allan, Witte, D. R., Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetic Medicine. 26, 4, p. 377-83 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Progression to impaired glucose regulation and diabetes in the population-based Inter99 study
Engberg, S., Vistisen, D., Lau, C., Glümer, C., Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetes Care. 32, p. 606-11Research output: Contribution to journal › Journal article › Research › peer-review
Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue
Grunnet, Louise Groth, Nilsson, E., Ling, C., Hansen, T., Pedersen, Oluf Borbye, Groop, L., Vaag, A. & Poulsen, P., 2009, In: Diabetes. p. 2402-2408 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spaedbørnsdiabetes kan ofte behandles med sulfonylurinstof i stedet for insulin
Lauridsen, M. H., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T. & Hertz, B., 2009, In: Ugeskrift for læger. 171, 23, p. 1923-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes
Andreasen, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Almind, K., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: BMC Medical Genetics. 10, 1, p. 17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
Holmkvist, J., Banasik, K., Andersen, G., Unoki, H., Jensen, T. S., Pisinger, C., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Brunak, Søren, Maeda, S., Hansen, T. & Pedersen, Oluf Borbye, 2009, In: PLoS ONE. 4, 6, p. e5872Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of a multimarker model for assessing risk of type 2 diabetes from a five-year prospective study of 6784 Danish people (Inter99)
Urdea, M., Kolberg, J., Wilber, J., Gerwien, R., Moler, E., Rowe, M., Jorgensen, P., Hansen, T., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2009, In: Journal of Diabetes Science and Technology. 3, 4, p. 748-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study
Boesgaard, T. W., Gjesing, A. P., Grarup, N., Rutanen, J., Jansson, P., Hribal, M. L., Sesti, G., Fritsche, A., Stefan, N., Staiger, H., Häring, H., Smith, U., Laakso, M., Pedersen, Oluf Borbye, Hansen, T. & EUGENE2 Consortium, E. C., 2009, In: PLoS ONE. 4, 9, p. e7236Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes
Zobel, D. P., Andreasen, C. H., Grarup, N., Eiberg, Hans Rudolf Lytchoff, Sørensen, Thorkild I.A., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2009, In: Diabetes. p. 757-764 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits
Rathcke, C. N., Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Hansen, T., Pedersen, Oluf Borbye & drb459, drb459, 2009, In: PLoS ONE. 4, 5, p. e5469Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in the gene encoding Kruppel-like factor 7 influences body fat: studies of 14,818 Danes
Zobel, D., Andreasen, C., Burgdorf, K., Andersson, E., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Maeda, S., Nakamura, Y., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: European Journal of Endocrinology. 160, 4, p. 603-9Research output: Contribution to journal › Journal article › Research › peer-review
ID: 919113
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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