Mikkel Østergaard

Mikkel Østergaard

Clinical Professor

Member of:

  • Internal Medicine: Rheumatology


  1. 2022
  2. Published

    Tapering of TNF inhibitors in axial spondyloarthritis in routine care-2-year clinical and MRI outcomes and predictors of successful tapering

    Wetterslev, M., Georgiadis, S., Sorensen, I. J., Pedersen, S. J., Christiansen, S. N., Hetland, Merete Lund, Brahe, C. H., Bakkegaard, M., Duer, A., Boesen, Mikael Ploug, Gosvig, K. K., Moller, J. M., Krogh, N. S., Jensen, B., gjc556, gjc556, Christensen, J., Hansen, A., Norregaard, J., Rogind, H. & Østergaard, Mikkel, 30 May 2022, In: Rheumatology. 61, 6, p. 2398-2412 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Morphological characteristics of sacroiliac joint MRI lesions in axial spondyloarthritis and control subjects

    Seven, S., Østergaard, Mikkel, Morsel-Carlsen, L., Sorensen, I. J., Bonde, B., Thamsborg, G., Lykkegaard, J. J. & Pedersen, S. J., 2 Mar 2022, In: Rheumatology. 61, 3, p. 1005-1017 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A novel fluorescence optical imaging scoring system for hand synovitis in rheumatoid arthritis-validity and agreement with ultrasound

    Ammitzbøll-Danielsen, M., Glinatsi, D., Terslev, Lene & Østergaard, Mikkel, 2022, In: Rheumatology. 61, 2, p. 636-647 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Blood chemokine levels are markers of disease activity but not predictors of remission in early rheumatoid arthritis

    Aldridge, J., Lundell, A., Andersson, K., Mark, L., Hetland, Merete Lund, Østergaard, Mikkel, Uhlig, T., Heiberg, M. S., Haavardsholm, E. A., Nurmohamed, M., Lampa, J., Nordström, D., Hørslev-Petersen, K., Gudbjornsson, B., Gröndal, G., van Vollenhoven, R. & Rudin, A., 2022, In: Clinical and Experimental Rheumatology. 40, 7, p. 1393-1402 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    CXCL13 predicts long-term radiographic status in early rheumatoid arthritis

    Greisen, S. R., Mikkelsen, C., Hetland, Merete Lund, Østergaard, Mikkel, Hørslev-Petersen, K., Junker, P., Stengaard-Petersen, K. & Deleuran, B., 2022, In: Rheumatology. 61, 6, p. 2590-2595 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Do tender joints in active psoriatic arthritis reflect inflammation assessed by ultrasound and magnetic resonance imaging?

    Felbo, S. K., Wiell, C., Østergaard, Mikkel, Poggenborg, R. P., Bøyesen, P., Hammer, H. B., Boonen, A., Pedersen, S. J., Sørensen, I. J., gjc556, gjc556, Slot, O., Møller, J. M., Szkudlarek, Marcin & Terslev, Lene, 2022, In: Rheumatology (Oxford, England). 61, 2, p. 723-733 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of initiating biologics compared to intensifying conventional DMARDs on clinical and MRI outcomes in established rheumatoid arthritis patients in clinical remission: Secondary analyses of the IMAGINE-RA trial

    Møller-Bisgaard, S., Hørslev-Petersen, K., Ejbjerg, B., Hetland, M. L., Christensen, R., Ørnbjerg, L. M., Glinatsi, D., Møller, J. M., Boesen, M., Stengaard-Pedersen, K., Madsen, O. R., Jensen, B., Villadsen, J. A., Hauge, E. M., Bennett, P., Hendricks, O., Asmussen, K., Kowalski, M., Lindegaard, H., Bliddal, H. & 7 others, Krogh, N. S., Ellingsen, T., Nielsen, A. H., Larsen, L., Jurik, A. G., Thomsen, Henrik S. & Østergaard, Mikkel, 2022, In: Scandinavian Journal of Rheumatology. 51, 4, p. 268-278

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effects of ixekizumab treatment on structural changes in the sacroiliac joint: MRI assessments at 16 weeks in patients with non-radiographic axial spondyloarthritis

    Maksymowych, W. P., Baraliakos, X., Lambert, R. G., Landewé, R., Sandoval, D., Carlier, H., Lisse, J., Li, X., Hojnik, M. & Østergaard, Mikkel, 2022, In: The Lancet Rheumatology. 4, 9, p. e626-e634

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Efficacy and Acceptability of Intermittent Aerobic Exercise on Polysomnography-Measured Sleep in People With Rheumatoid Arthritis With Self-Reported Sleep Disturbance: A Randomized Controlled Trial

    Loeppenthin, K., Esbensen, Bente Appel, Midtgaard, Julie, Østergaard, Mikkel, Christensen, J. F., Tolver, Anders, Thomsen, T., Bech, J. S. & Jennum, Poul, 2022, In: ACR Open Rheumatology. 4, 5, p. 395-405 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Efficacy and safety of guselkumab in biologic-naïve patients with active axial psoriatic arthritis: study protocol for STAR, a phase 4, randomized, double-blinded, placebo-controlled trial

    Gladman, D. D., Mease, P. J., Bird, P., Soriano, E. R., Chakravarty, S. D., Shawi, M., Xu, S., Quinn, S. T., Gong, C., Leibowitz, E., Poddubnyy, D., Tam, L. S., Helliwell, P. S., Kavanaugh, A., Deodhar, A., Østergaard, Mikkel & Baraliakos, X., 2022, In: Trials. 23, 743.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Enthesitis in patients with psoriatic arthritis and axial spondyloarthritis – data from the Danish nationwide DANBIO registry

    Mathew, A. J., Glintborg, Bente, Krogh, N. S., Hetland, Merete Lund & Østergaard, Mikkel, 2022, In: Seminars in Arthritis and Rheumatism. 52, 151948.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    European bio-naïve spondyloarthritis patients initiating TNF inhibitor: time trends in baseline characteristics, treatment retention and response

    Christiansen, S. N., Ørnbjerg, L. M., Rasmussen, S. H., Loft, A. G., Askling, J., Iannone, F., Zavada, J., Michelsen, B., Nissen, M., Onen, F., Santos, M. J., Pombo-Suarez, M., Relas, H., Macfarlane, G. J., Tomsic, M., Codreanu, C., Gudbjornsson, B., Van der Horst-Bruinsma, I., Di Giuseppe, D., Glintborg, B. & 16 others, Gremese, E., Pavelka, K., Kristianslund, E. K., Ciurea, A., Akkoc, N., Barcelos, A., Sánchez-Piedra, C., Peltomaa, R., Jones, G. T., Rotar, Z., Ionescu, R., Grondal, G., Van de Sande, M. G. H., Laas, K., Østergaard, Mikkel & Hetland, Merete Lund, 2022, In: Rheumatology. 61, 9, p. 3799-3807 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Extracellular matrix protein turnover markers are associated with axial spondyloarthritis-a comparison with postpartum women and other non-axial spondyloarthritis controls with or without back pain

    Port I Linares, H., Nielsen, S. H., Madsen, S. F., Bay-Jensen, A., Karsdal, M., Seven, S., Sørensen, I. J., Morsel-Carlsen, L., Østergaard, Mikkel & Pedersen, S. J., 2022, In: Arthritis Research & Therapy. 24, 152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Filgotinib decreases both vertebral body and posterolateral spine inflammation in ankylosing spondylitis: Results from the TORTUGA trial

    Maksymowych, W. P., Østergaard, Mikkel, Landew, R., Barchuk, W., Liu, K., Gilles, L., Hendrikx, T., Besuyen, R. & Baraliakos, X., 2022, In: Rheumatology. 61, 6, p. 2388-2397 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Flare during tapering of biological DMARDs in patients with rheumatoid arthritis in routine care: characteristics and predictors

    Terslev, L., Ostergaard, M., Georgiadis, S., Brahe, C. H., Ellegaard, K., Dohn, U. M., Fana, V., Møller, T., Juul, L., Huynh, T. K., Krabbe, S., Ornbjerg, L. M., Glinatsi, D., Røgind, H., Hansen, A., Nørregaard, J., Jacobsen, S., Jensen, D. V., Manilo, N., Asmussen, K. & 6 others, Boesen, Mikael Ploug, Rastiemadabadi, Z., Morsel-Carlsen, L., Møller, J. M., Krogh, N. S. & Hetland, Merete Lund, 2022, In: RMD Open. 8, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Impact of filgotinib on sacroiliac joint magnetic resonance imaging structural lesions at 12 weeks in patients with active ankylosing spondylitis (TORTUGA trial)

    Maksymowych, W. P., Østergaard, Mikkel, Landewé, R., Barchuk, W., Liu, K., Tasset, C., Gilles, L., Hendrikx, T., Besuyen, R. & Baraliakos, X., 2022, In: Rheumatology. 61, 5, p. 2063-2071 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Impact of non-pharmacological interventions targeting sleep disturbances or disorders in patients with inflammatory arthritis: A systematic review and meta-analysis of randomized trials

    Latocha, K. M., Løppenthin, K. B., Al-Bazy, S., Albrechtsen, T. L., Jensen, H. E., Østergaard, Mikkel, Jennum, Poul, Esbensen, Bente Appel & Christensen, R., 2022, In: Arthritis Care & Research. 74, 12, p. 2108-2118

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Implementation of the OMERACT Psoriatic Arthritis Magnetic Resonance Imaging Scoring System in a randomized phase IIb study of abatacept in psoriatic arthritis

    Østergaard, Mikkel, Bird, P., Pachai, C., Du, S., Wu, C., Landis, J., Fuerst, T., Ahmad, H. A., Connolly, S. E. & Conaghan, P. G., 2022, In: Rheumatology. 61, 11, p. 4305-4313 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Improving the design of RCTs in non-radiographic axial spondyloarthritis

    Maksymowych, W. P., Lambert, R. G. W., Caplan, L., van den Bosch, F. E. & Østergaard, Mikkel, 2022, In: Nature Reviews Rheumatology. 18, 8, p. 481-489

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study

    Attauabi, M., Madsen, G. R., Bendtsen, F., Wewer, A. V., Wilkens, R., Ilvemark, J., Vladimirova, N., Jensen, A. B., Jensen, F. K., Hansen, S. B., Siebner, H. R., Nielsen, Y. J. W., Møller, J. M., Thomsen, H. S., Thomsen, S. F., Ingels, H. A. S., Theede, K., Boysen, T., Bjerrum, J. T., Jakobsen, C. & 13 others, Dorn-Rasmussen, M., Jansson, S., Yao, Y., Burian, E. A., Møller, F. T., Fana, V., Wiell, C., Terslev, Lene, Østergaard, Mikkel, Bertl, K., Stavropoulos, A., Seidelin, Jakob Benedict & Burisch, J., 2022, In: BMJ Open. 12, 6, e055779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Ixekizumab in radiographic axial spondyloarthritis with and without elevated C-reactive protein or positive magnetic resonance imaging

    Maksymowych, W. P., Bolce, R., Gallo, G., Seem, E., Geneus, V. J., Sandoval, D. M., Østergaard, Mikkel, Tada, K., Baraliakos, X., Deodhar, A. & Gensler, L. S., 2022, In: Rheumatology. 61, 11, p. 4324-4334 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Levels of extracellular matrix metabolites are associated with changes in Ankylosing Spondylitis Disease Activity Score and MRI inflammation scores in patients with axial spondyloarthritis during TNF inhibitor therapy

    Holm Nielsen, S., Sun, S., Bay-Jensen, A. C., Karsdal, M., Sørensen, I. J., Weber, U., Loft, A. G., Kollerup, Gina Birgitte, Thamsborg, G., gjc556, gjc556, Møller, J., Østergaard, Mikkel & Pedersen, S. J., 2022, In: Arthritis Research and Therapy. 24, 279.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Long-term Behavioral Changes During the COVID-19 Pandemic and Impact of Vaccination in Patients With Inflammatory Rheumatic Diseases

    Glintborg, Bente, Jensen, D. V., Terslev, Lene, Hendricks, O., Østergaard, Mikkel, Rasmussen, S. H., Jensen, M. P., Adelsten, T., Colic, A., Danebod, K., Kildemand, M., Loft, A. G., Munk, H. L., Pedersen, J. K., Østgård, R. D., Sørensen, C. M., Krogh, N. S., Agerbo, J. N., Ziegler, C. & Hetland, Merete Lund, 2022, In: Journal of Rheumatology. 49, 10, p. 1163-1172 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    MRI lesions of the spine in patients with axial spondyloarthritis: an update of lesion definitions and validation by the ASAS MRI working group

    Baraliakos, X., Østergaard, Mikkel, Lambert, R. G. W., Eshed, I., Machado, P. M., Pedersen, S. J., Weber, U., de Hooge, M., Sieper, J., Poddubnyy, D., Rudwaleit, M., Van Der Heijde, D., Landewé, R. B. M. & Maksymowych, W. P., 2022, In: Annals of the Rheumatic Diseases. 81, 9, p. 1243-1251

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Musculoskeletal pain in psoriasis-relation to inflammation and additional value of ultrasound in psoriatic arthritis classification

    Felbo, S. K., Terslev, Lene, Juul Sørensen, I., Hendricks, O., Kuettel, D., Lederballe Pedersen, R., Chrysidis, S., Duer, A., Zachariae, Claus, Skov, Lone & Østergaard, Mikkel, 2022, In: Rheumatology. 61, 7, p. 2835-2847 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Nationwide, large-scale implementation of an online system for remote entry of patient-reported outcomes in rheumatology: characteristics of users and non-users and time to first entry

    Glintborg, Bente, Jensen, D. V., Terslev, Lene, Hendricks, O., Østergaard, Mikkel, Rasmussen, S. H., Jensen, M. P., Adelsten, T., Colic, A., Danebod, K., Kildemand, M., Loft, A. G., Munk, H. L., Pedersen, J. K., Østgård, R. D., Sørensen, C. M., Krogh, N. S., Agerbo, J., Ziegler, C. & Hetland, Merete Lund, 2022, In: RMD Open. 8, 2, e002549.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Prediction of flare following remission and treatment withdrawal in early rheumatoid arthritis: post hoc analysis of a phase IIIb trial with abatacept

    Ahmad, H. A., Baker, J. F., Conaghan, P. G., Emery, P., Huizinga, T. W. J., Elbez, Y., Banerjee, S. & Østergaard, Mikkel, 2022, In: Arthritis Research and Therapy. 24, 1, 47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Predictors of ASDAS-CRP inactive disease in axial spondyloarthritis during treatment with TNF-inhibitors: Data from the EuroSpA collaboration

    Ørnbjerg, L. M., Linde, L., Georgiadis, S., Rasmussen, S. H., Lindström, U., Askling, J., Michelsen, B., Giuseppe, D. D., Wallman, J. K., Pavelka, K., Závada, J., Nissen, M. J., Jones, G. T., Relas, H., Pirilä, L., Tomšič, M., Rotar, Z., Geirsson, A. J., Gudbjornsson, B., Kristianslund, E. K. & 14 others, van sder Horst-Bruinsma, I., Loft, A. G., Laas, K., Iannone, F., Corrado, A., Ciurea, A., Santos, M. J., Santos, H., Codreanu, C., Akkoc, N., Gunduz, O. S., Glintborg, Bente, Østergaard, Mikkel & Hetland, Merete Lund, 2022, In: Seminars in Arthritis and Rheumatism. 56, 152081.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Real-World Six- and Twelve-Month Drug Retention, Remission, and Response Rates of Secukinumab in 2,017 Patients With Psoriatic Arthritis in Thirteen European Countries

    Michelsen, B., Georgiadis, S., Di Giuseppe, D., Loft, A. G., Nissen, M. J., Iannone, F., Pombo-Suarez, M., Mann, H., Rotar, Z., Eklund, K. K., Kvien, T. K., Santos, M. J., Gudbjornsson, B., Codreanu, C., Yilmaz, S., Wallman, J. K., Brahe, C. H., Möller, B., Favalli, E. G., Sánchez-Piedra, C. & 13 others, Nekvindova, L., Tomsic, M., Trokovic, N., Kristianslund, E. K., Santos, H., Löve, T. J., Ionescu, R., Pehlivan, Y., Jones, G. T., van der Horst-Bruinsma, I., Ørnbjerg, L. M., Østergaard, Mikkel & Hetland, Merete Lund, 2022, In: Arthritis Care and Research. 74, 7, p. 1205-1218 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Retrospective longitudinal assessment of ultrasound gout lesions using the OMERACT semi-quantitative scoring system

    Christiansen, S. N., Østergaard, Mikkel, Slot, O., Fana, V. & Terslev, Lene, 2022, In: Rheumatology. 61, 12, p. 4711-4721 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Secukinumab and Sustained Reduction in Fatigue in Patients With Ankylosing Spondylitis: Long-Term Results of Two Phase III Randomized Controlled Trials

    Kvien, T. K., Conaghan, P. G., Gossec, L., Strand, V., Østergaard, Mikkel, Poddubnyy, D., Williams, N., Porter, B., Shete, A., Gilloteau, I. & Deodhar, A., 2022, In: Arthritis Care and Research. 74, 5, p. 759-767 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Sex differences in remission rates over 24 weeks among three different biological treatments compared to conventional therapy in patients with early rheumatoid arthritis (NORD-STAR): a post-hoc analysis of a randomised controlled trial

    Lend, K., van Vollenhoven, R. F., Lampa, J., Hetland, Merete Lund, Haavardsholm, E. A., Nordström, D., Nurmohamed, M., Gudbjornsson, B., Rudin, A., Østergaard, Mikkel, Uhlig, T., Grondal, G., Hørslev-Petersen, K., Heiberg, M. S., Sokka-Isler, T., Koopman, F. A., Twisk, J. W. R. & van der Horst-Bruinsma, I., 2022, In: The Lancet Rheumatology. 4, 10, p. e688-e698

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Spinal Radiographic Progression and Predictors of Progression in Patients With Radiographic Axial Spondyloarthritis Receiving Ixekizumab Over 2 Years

    van der Heijde, D., Østergaard, Mikkel, Reveille, J. D., Baraliakos, X., Kronbergs, A., Sandoval, D. M., Li, X., Carlier, H., Adams, D. H. & Maksymowych, W. P., 2022, In: Journal of Rheumatology. 49, 3 , p. 265-273 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    T-cell immunoglobulin and mucin domain 3 is upregulated in rheumatoid arthritis, but insufficient in controlling inflammation

    Skejoe, C., Hansen, A. S., Stengaard-Pedersen, K., Junker, P., Hoerslev-Pedersen, K., Hetland, Merete Lund, Østergaard, Mikkel, Greisen, S., Hvid, M., Deleuran, M. & Deleuran, B., 2022, In: American journal of clinical and experimental immunology. 11, 3, p. 34-44 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The Programmed Death-1 Pathway Counter-Regulates Inflammation-Induced Osteoclast Activity in Clinical and Experimental Settings

    Greisen, S. R., Kragstrup, T. W., Thomsen, J. S., Hørslev-Pedersen, K., Hetland, Merete Lund, Stengaard-Pedersen, K., Østergaard, Mikkel, Ørnbjerg, L., Junker, P., Sharpe, A. H., Freeman, G. J., Hvid, M., Moestrup, S. K., Hauge, E. M. & Deleuran, B., 2022, In: Frontiers in Immunology. 13, 773946.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Training and assessment of musculoskeletal ultrasound and injection skills-a systematic review

    Carstensen, S. M. D., Velander, M. J., Konge, Lars, Østergaard, Mikkel, Pfeiffer Jensen, M., Just, S. A. & Terslev, Lene, 2022, In: Rheumatology. 61, 10, p. 3889-3901 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Ultrasound of the Heel Improves Diagnosis—Tender Entheses in the Heel Region Rarely Corresponds to Inflammatory Enthesitis in Patients with Peripheral Spondyloarthritis

    Felbo, S. K., Østergaard, Mikkel, Sørensen, I. J. & Terslev, Lene, 2022, In: Journal of Clinical Medicine. 11, 9, 2325.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    What Constitutes a Positive MRI for Clinical Trial Recruitment of Psoriatic Arthritis Patients With Axial Involvement?

    Maksymowych, W. P. & Østergaard, Mikkel, 2022, In: The Journal of rheumatology. 49, 6 Suppl. 1, p. 72-74 3 p.

    Research output: Contribution to journalReviewResearchpeer-review

ID: 6953