Kirsten Grønbæk

Kirsten Grønbæk

Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. 2018
  2. Published

    Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial

    Jerkeman, M., Eskelund, C. W., Hutchings, M., Räty, R., Wader, K. F., Laurell, A., Toldbod, H., Pedersen, L. B., Niemann, Carsten, Dahl, C., Kuitunen, H., Geisler, C. H., Grønbæk, Kirsten & Kolstad, A., 2018, In: The Lancet Haematology. 5, 3, p. e109-e116 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Lenalidomide plus bendamustine-rituximab does not overcome the adverse impact of TP53 mutations in mantle cell lymphoma

    Eskelund, C. W., Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Pedersen, L. B., Geisler, C. H., Jerkeman, M. & Grønbæk, Kirsten, 2018, In: Haematologica. 103, 11, p. e541-e543 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  4. Published

    Long Non-Coding RNAs Guide the Fine-Tuning of Gene Regulation in B-Cell Development and Malignancy

    Dahl, M., Kristensen, L. S. & Grønbæk, Kirsten, 2018, In: International Journal of Molecular Sciences. 19, 9, 26 p., 2475.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Long-term clinical outcomes of patients with hematologically unexplained cytopenia after routine assessment: A single center study

    Johansen, M. M., Andersen, M. A., Grønbæk, Kirsten & Hansen, Jakob Werner, 2018, In: European Journal of Haematology. 101, 5, p. 595–603 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Mother–child transmission of epigenetic information by tunable polymorphic imprinting

    Carpenter, B. L., Zhou, W., Madaj, Z., DeWitt, A. K., Ross, J. P., Grønbæk, Kirsten, Liang, G., Clark, S. J., Molloy, P. L. & Jones, P. A., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. E11970-E11977 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Specific Lipid and Metabolic Profiles of R-CHOP-Resistant Diffuse Large B-Cell Lymphoma Elucidated by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and in Vivo Imaging

    Barré, F. P. Y., Claes, B. S. R., Dewez, F., Peutz-Kootstra, C., Munch-Petersen, H. F., Grønbæk, Kirsten, Lund, Anders H., Heeren, R. M. A., Côme, Christophe Roger Michel & Cillero-Pastor, B., 2018, In: Analytical Chemistry. 90, 24, p. 14198-14206 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Twin DNA Methylation Profiling Reveals Flare-Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus

    Ulff-Møller, C. J., Asmar, F., Liu, Y., Svendsen, A. J., Busato, F., Grønbæk, Kirsten, Tost, J. & Jacobsen, Søren, 2018, In: Arthritis & rheumatology (Hoboken, N.J.). 70, 6, p. 878-890 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published

    Mature lymphoid malignancies: origin, stem cells, and chronicity

    Husby, Simon & Grønbæk, Kirsten, Nov 2017, In: Blood advances. 1, 25, p. 2444-2455 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    DNA Methyltransferase Inhibitors in Myeloid Cancer: Clonal Eradication or Clonal Differentiation?

    mxz703, mxz703 & Grønbæk, Kirsten, Sep 2017, In: Cancer journal (Sudbury, Mass.). 23, 5, p. 277-285 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period

    Hansen, Jakob Werner, Sandholdt, H., Siersma, Volkert Dirk, mxz703, mxz703, Holmberg, S., Bjerrum, O. W., Hasselbalch, Hans Carl, Olivarius, Niels de Fine, Grønbæk, Kirsten & Andersen, Christen Bertel L, Jul 2017, In: American Journal of Hematology. 92, 7, p. E130-E132 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  13. Published

    Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

    Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1–Infected Individuals and Are Associated With Markers of Systemic Inflammation

    Ballegaard, V., Ralfkiaer, U., Pedersen, K. K., Hove, M., Koplev, S., Brændstrup, P., Ryder, L. P., Madsen, H. O., Gerstoft, Jan, Grønbæk, Kirsten & Nielsen, S. D., 1 Apr 2017, In: Journal of Acquired Immune Deficiency Syndromes. 74, 4, p. e104-e113

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Molecular Monitoring after Autologous Stem Cell Transplantation and Preemptive Rituximab Treatment of Molecular Relapse; Results from the Nordic Mantle Cell Lymphoma Studies (MCL2 and MCL3) with Median Follow-Up of 8.5 Years

    Kolstad, A., Pedersen, L. B., Eskelund, C. W., Husby, S., Grønbæk, K., Jerkeman, M., Laurell, A., Räty, R., Elonen, E., Andersen, N. S., Brown, P. D. N., Kimby, E., Bentzen, H., Sundström, C., Ehinger, M., Karjalainen-Lindsberg, M. L., Delabie, J., Ralfkiær, E., Fagerli, U. M., Nilsson-Ehle, H. & 5 others, Lauritzsen, G. F., Kuittinen, O., Niemann, Carsten, Geisler, C. H. & the Nordic Lymphoma Group, T. N. L. G., Mar 2017, In: Biology of Blood and Marrow Transplantation. 23, 3, p. 428-435 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

    Eskelund, C. W., Dahl, C., Hansen, Jakob Werner, Westman, M., Kolstad, A., Pedersen, L. B., Montano-Almendras, C. P., Husby, Simon, Freiburghaus, C., Ek, S., Vestergaard, Anja Holm, Niemann, Carsten, Raty, R., Brown, Peter de Nully, Geisler, C. H., Andersen, M. K., Guldberg, P., Jerkeman, M. & Grønbæk, Kirsten, 2017, In: Blood. 130, 17, p. 1903-1910 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

    Myrtue Nielsen, H., Andersen, Christen Bertel L, Westman, M., Sommer Kristensen, L., Asmar, F., Arvid Kruse, T., Thomassen, M., Stauffer Larsen, T., Skov, V., Lotte Hansen, L., Weis Bjerrum, O., Hasselbalch, Hans Carl, Punj, V. & Grønbæk, Kirsten, 2017, In: Scientific Reports. 7, 11 p., 6774.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Nucleosome Positioning and NDR Structure at RNA Polymerase III Promoters

    Helbo, A. S., Lay, F. D., Jones, P. A., Liang, G. & Grønbæk, Kirsten, 2017, In: Scientific Reports. 7, 11 p., 41947.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Årsagen til uforklaret cytopeni kan ofte findes med fokuseret DNA-sekventering

    Hansen, J. W., Husby, S. & Grønbæk, Kirsten, 2017, In: Ugeskrift for Laeger. 179, 25, 4 p., V03170179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2016
  21. Published

    Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

    Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungström, V., Schneider, M., Yoshida, K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C. M., Couronné, L. & 35 others, Lenze, D., Baldus, C. D., Bastard, C., Okosun, J., Fitzgibbon, J., Dörken, B., Drexler, H. G., Roos-Weil, D., Schmitt, C. A., Munch-Petersen, H. D., Zenz, T., Hansmann, M., Strefford, J. C., Enblad, G., Bernard, O. A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Grønbæk, Kirsten, Lopez-Guillermo, A., Ogawa, S., Küppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R., Ott, G., Vassilakopoulos, T. P., Hummel, M., Rosenquist, R. & Damm, F., 8 Dec 2016, In: Blood. 128, 23, p. 2666-2670 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes

    Hansen, Jakob Werner, Westman, M. K., Sjö, Lene Dissing, Saft, L., Sommer Kristensen, L., mxz703, mxz703, Treppendahl, M., Andersen, M. K. & Grønbæk, Kirsten, Dec 2016, In: American Journal of Hematology. 91, 12, p. 1234-1238 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau

    Eskelund, C. W., Kolstad, A., Jerkeman, M., Räty, R., Laurell, A., Eloranta, S., Smedby, K. E., Husby, S., Pedersen, L. B., Andersen, N. S., Eriksson, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J. & 7 others, Karjalainen-Lindsberg, M., Workman, C. T., Garde, C., Elonen, E., Brown, Peter de Nully, Grønbæk, Kirsten & Geisler, C. H., Nov 2016, In: British Journal of Haematology. 175, 3, p. 410-418 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine

    Liu, M., Ohtani, H., Zhou, W., mxz703, mxz703, Charlet, J., Zhang, Y. W., Shen, H., Baylin, S. B., Liang, G., Grønbæk, Kirsten & Jones, P. A., 13 Sep 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 37, 7 p., 10238-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Immune Mechanisms in Myelodysplastic Syndrome

    Glenthøj, A., mxz703, mxz703, Hansen, Jakob Werner, Hadrup, S. R., O'Connell, C. & Grønbæk, Kirsten, 15 Jun 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 13 p., 944.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy

    Munch-Petersen, H. D., Asmar, F., Dimopoulos, K., Areškevičiūtė, A., Brown, Peter de Nully, Girkov, M. S., Pedersen, A., Sjö, Lene Dissing, Heegaard, Steffen, Broholm, H., Kristensen, L. S., Ralfkiaer, E. & Grønbæk, Kirsten, 22 Apr 2016, In: Acta Neuropathologica Communications. 4, 13 p., 40.

    Research output: Contribution to journalJournal articleResearch

  27. Published

    Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma

    Kristensen, L. S., Michaelsen, Signe Regner, Dyrbye, H., Aslan, D., Grunnet, K., Christensen, I. J., Poulsen, H. S., Grønbæk, Kirsten & Broholm, H., Mar 2016, In: Journal of Neuropathology and Experimental Neurology. 75, 3, p. 246-55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

    Sommer Kristensen, L., Hansen, Jakob Werner, Kristensen, S. S., Tholstrup, D., Harsløf, L. B. S., Pedersen, Ole Birger Vesterager, Brown, Peter de Nully & Grønbæk, Kirsten, 2016, In: Clinical Epigenetics. 8, 11 p., 95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Lenalidomide-bendamustine-rituximab in untreated mantle cell lymphoma > 65 years with untreated mantle cell lymphoma

    Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Grønbæk, Kirsten, Sundberg, J., Pedersen, L. B., Ralfkiær, E., Karjalainen-Lindsberg, M., Sundström, C., Ehinger, M., Geisler, C. & Jerkeman, M., 2016, In: Blood. 128, 14, p. 1814-1820

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations

    Aslan, D., Garde, C., Nygaard, M. K., Helbo, A. S., Dimopoulos, K., Hansen, Jakob Werner, Severinsen, M. T., Treppendahl, M. B., Sjö, Lene Dissing, Grønbæk, Kirsten & Sommer Kristensen, L., 2016, In: OncoTarget. 7, 9, p. 9951-63 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2015
  32. Published

    MICRORNA 203 CONTROLS T-CELL LYMPHOMAGENESIS BY TARGETING IL-2 RECEPTOR SIGNALING

    Ralfkiaer, U., Jansson, Martin David, Kopp, K., Willerslev-Olsen, A., Asmar, F., Krejsgaard, T., Brown, P., Gniadecki, R., Woetmann, Anders , Lund, Anders H., Ødum, Niels & Grønbæk, Kirsten, 22 Jun 2015, In: Haematologica. 100, supplement 1, p. 104-105 2 p., P317.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  33. Published

    miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator

    Husby, S., Ralfkiaer, U., Garde, C., Zandi, R., Ek, S., Kolstad, A., Jerkeman, M., Laurell, A., Räty, R., Pedersen, L. B., Pedersen, A., Ehinger, M., Sundström, C., Karjalainen-Lindsberg, M-L., Delabie, J., Clasen-Linde, E., Brown, P. D. N., Cowland, J. B., Workman, C. T., Geisler, C. H. & 1 others, Grønbæk, Kirsten, 23 Apr 2015, In: Blood. 125, 17, p. 2669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Differential Expression of miR-155 and miR-21 in Tumor and Stroma Cells in Diffuse Large B-Cell Lymphoma

    Munch-Petersen, H. D., Ralfkiaer, U., Sjö, Lene Dissing, Hother, C., Asmar, F., Nielsen, B. S., Brown, P., Ralfkiaer, E. & Grønbæk, Kirsten, Mar 2015, In: Applied Immunohistochemistry & Molecular Morphology. 23, 3, p. 188-195 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Loss of PRDM11 promotes MYC-driven lymphomagenesis

    Fog-Tonnesen, C. K., Asmar, F., Côme, Christophe Roger Michel, Jensen, K. T., Johansen, Jens Vilstrup, Bou Kheir, T., Jacobsen, L., Friis, C., Louw, A., Rosgaard, L., Øbro, N. F., Marquart, Hanne Vibeke Hansen, Anthonsen, K., Braat, A. K., van Lohuizen, M., Ralfkiaer, E., Grønbæk, Kirsten & Lund, Anders H., 19 Feb 2015, In: Blood. 125, 8, p. 1272-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Allele-Specific DNA Methylation Detection by Pyrosequencing®

    Sommer Kristensen, L., Johansen, Jens Vilstrup & Grønbæk, Kirsten, 2015, Pyrosequencing: Methods and Protocols. Lehmann, U. & Tost, J. (eds.). Vol. 1315. p. 271-89 19 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  37. Published

    Development and blind clinical validation of a microRNA based predictor of response to treatment with R-CHO(E)P in DLBCL

    Knudsen, S., Hother, C., Grønbæk, Kirsten, Jensen, T., Hansen, A., Mazin, W., Dahlgaard, J., Møller, M. B., Ralfkiær, E. & Brown, P. D. N., 2015, In: P L o S One. 10, 2, 15 p., e0115538.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients

    Helbo, A. S., Treppendahl, M. B., Aslan, D., Dimopoulos, K., Nandrup-Bus, C., Holm, M. S., Andersen, M. K., Liang, G., Sommer Kristensen, L. & Grønbæk, Kirsten, 2015, In: Genes. 6, 4, p. 977-90 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation

    mxz703, mxz703, Treppendahl, M. B., Skovbo, A., Holm, M. S., Friis, L. S., Hokland, M. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 11, p. 9612-26 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

    Andersen, Christen Bertel L, Nielsen, H. M., Sommer Kristensen, L., Helbo, A. S., Vikeså, J., Jønson, L., Nielsen, Finn Cilius, Hasselbalch, Hans Carl, Bjerrum, O. W., Punj, V. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 38, p. 40588-97 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2014
  42. Published

    MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

    Ralfkiaer, U., Lindahl, L. M., Litman, Thomas, Gjerdrum, Lise Mette Rahbek, Ahler, C. B., Gniadecki, R., Marstrand, T., Fredholm, S., Iversen, L., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Glue, C., Røpke, M. A., Woetmann, A., Skov, Lone, Grønbæk, Kirsten & Ødum, Niels, Dec 2014, In: Anticancer Research. 34, 12, p. 7207-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

    Gingold, H., Tehler, D., Christoffersen, N. R., Nielsen, M. M., Asmar, F., Kooistra, S. M., Christophersen, N. S., Christensen, L. L., Borre, M., Sørensen, K. D., Andersen, L. D., Andersen, C. L., Hulleman, E., Wurdinger, T., Ralfkiær, E., Helin, K., Grønbæk, K., Orntoft, T., Waszak, S. M., Dahan, O. & 3 others, Pedersen, J. S., Lund, Anders H. & Pilpel, Y., 11 Sep 2014, In: Cell. 158, 6, p. 1281-92 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Circulating YKL-40 in patients with essential thrombocythemia and polycythemia vera treated with the novel histone deacetylase inhibitor vorinostat

    Andersen, C. L., Bjørn, M. E., McMullin, M. F., Harrison, C., Samuelsson, J., Ejerblad, E., Zweegman, S., Fernandes, S., Bareford, D., Knapper, S., Löfvenberg, E., Linder, O., Andreasson, B., Ahlstrand, E., Jensen, M. K., Bjerrum, O. W., Vestergaard, H., Larsen, H., Klausen, T. W., Mourits-Andersen, T. & 5 others, Skov, V., Thomassen, M., Kruse, T., Grønbæk, Kirsten & Hasselbalch, H. C., Jul 2014, In: Leukemia Research. 38, 7, p. 816-821 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    SOX11 and TP53 add prognostic information to MIPI in a homogenously treated cohort of mantle cell lymphoma – a Nordic Lymphoma Group study

    Nordström, L., Sernbo, S., Eden, P., Grønbæk, Kirsten, Kolstad, A., Räty, R., Karjalainen, M., Geisler, C., Ralfkiaer, E., Sundström, C., Laurell, A., Delabie, J., Ehinger, M., Jerkeman, M. & Ek, S., Jul 2014, In: British Journal of Haematology. 166, 1, p. 98-108 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another “double hit” lymphoma with very poor outcome?

    Asmar, F., Hother, C., Kulosman, G., Treppendahl, M. B., Nielsen, H. M., Ralfkiaer, U., Pedersen, A., Møller, M. B., Ralfkiaer, E., de Nully Brown, P. & Grønbæk, Kirsten, 15 Apr 2014, In: OncoTarget. 5, 7, p. 1912-25 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Predicting response to epigenetic therapy

    Treppendahl, M. B., Sommer Kristensen, L. & Grønbæk, Kirsten, Jan 2014, In: The Journal of Clinical Investigation. 124, 1, p. 47-55 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    5-Azacytidine treatment sensitizes tumor cells to T-cell mediated cytotoxicity and modulates NK cells in patients with myeloid malignancies

    Gang, A. O., Frøsig, T. M., Brimnes, M. K., Lyngaa, R., Treppendahl, M. B., Grønbæk, Kirsten, Dufva, I. H., Straten, P. T. & Hadrup, S. R., 2014, In: Blood Cancer Journal. 4, 3, p. 1-9 9 p., e197.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia

    Toft-Petersen, M., Kjeldsen, E., Nederby, L., Grønbæk, Kirsten, Hokland, P. & Roug, A. S., 2014, In: Leukemia Research Reports. 3, 2, p. 94-97 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma

    Kristensen, L. S., Asmar, F., Dimopoulos, K., Nygaard, M. K., Aslan, D., Hansen, Jakob Werner, Ralfkiaer, E. & Grønbæk, Kirsten, 2014, In: OncoTarget. 5, 20, p. 9798-810 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial

    Holm, M., Dybedahl, I., Holm, M., Karimi, M., Brandefors, L., Garelius, H., Grövdal, M., Dufva, I. H., Grønbæk, Kirsten, Jansson, M., Marcher, C., Nilsson, L., Kittang, A. O., Porwit, A., Saft, L., Möllgård, L. & Hellström-Lindberg, E., 2014, In: Pediatric Blood & Cancer. 4, 3, p. 1-7 7 p., e189.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Nordic MCL3 study: 90Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma

    Kolstad, A., Laurell, A., Jerkeman, M., Grønbæk, K., Elonen, E., Räty, R., Pedersen, L. B., Loft, A., Bogsrud, T. V., Kimby, E., Hansen, P. B., Fagerli, U-M., Nilsson-Ehle, H., Lauritzsen, G. F., Lehmann, A. K., Sundstrom, C., Karjalainen-Lindsberg, M-L., Ralfkiaer, E., Ehinger, M., Delabie, J. & 7 others, Bentzen, H., Schildt, J., Kostova-Aherdan, K., Frederiksen, H., Brown, P. D. N., Geisler, C. H. & Nordic Lymphoma Group, N. L. G., 2014, In: Blood. 123, 19, p. 2953 - 2959 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Paraneoplastisk pancytopeni hos en patient med uerkendt lungecancer

    Hansen, J. W., Sjö, L. & Grønbæk, Kirsten, 2014, In: Ugeskrift for Laeger. 176, 19, p. 2-3 2 p., V11130675.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The role of epigenetics in the biology of multiple myeloma

    Dimopoulos, K., Gimsing, P. & Grønbæk, Kirsten, 2014, In: Blood Cancer Journal. 4, 5, p. 1-10 10 p., e207.

    Research output: Contribution to journalReviewResearchpeer-review

  55. Published

    Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas

    Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2013
  57. Published

    Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma

    Asmar, F., Punj, V., Christensen, J. A., Pedersen, M. T., Pedersen, A., Nielsen, A. B., Hother, C., Ralfkiaer, U., Brown, Peter de Nully, Ralfkiaer, E., Helin, K. & Grønbæk, Kirsten, Dec 2013, In: Haematologica. 98, 12, p. 1912-20 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    MicroRNA profiling in ocular adnexal lymphoma: a role for MYC and NFKB1 mediated dysregulation of microRNA expression in aggressive disease

    Hother, C., Rasmussen, P. K., Joshi, T., Reker, D., Ralfkiær, U., Workman, C. T., Heegaard, Steffen, Ralfkiær, E. & Grønbæk, Kirsten, Aug 2013, In: Investigative Ophthalmology & Visual Science. 54, 8, p. 5169-75 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Aberrant microRNA expression in multiple myeloma

    Dimopoulos, K., Gimsing, P. & Grønbæk, Kirsten, 2013, In: European Journal of Haematology. 91, 2, p. 95-105 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  60. Published

    Analysis of epigenetic modifications of DNA in human cells

    Kristensen, L. S., Treppendahl, M. B. & Grønbæk, Kirsten, 2013, In: Current Protocols in Human Genetics. Suppl. 77, 22 p., Unit20.2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Clonal expansion of renal cell carcinoma-infiltrating T lymphocytes

    Sittig, S., Køllgaard, T., Grønbæk, Kirsten, Idorn, M., Hennenlotter, J., Stenzl, A., Gouttefangeas, C. & Thor Straten, P., 2013, In: OncoImmunology. 2, 9, p. 1-9 9 p., e26014.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Investigation of MGMT and DAPK1 methylation patterns in diffuse large B-cell lymphoma using allelic MSP-pyrosequencing

    Kristensen, L. S., Treppendahl, M. B., Asmar, F., Girkov, M. S., Nielsen, H. M., Kjeldsen, T. E., Ralfkiaer, E., Hansen, L. L. & Grønbæk, Kirsten, 2013, In: Scientific Reports. 3, 11 p., 2789.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Kinetics of del(7 q) driven leukemogenesis in a patient with JAK2 V617F and TET2 mutated chronic myeloproliferative neoplasm

    Herborg, L. L., Nederby, L., Kjeldsen, E., Grønbæk, Kirsten, Hokland, P., Hansen, C. M. H., Celik Hansen, M. & Roug, A. S., 2013, In: Leukemia Research Reports. 2, 2, p. 51-53 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    MicroRNAs in mantle cell lymphoma

    Husby, Simon, Geisler, C. & Grønbæk, Kirsten, 2013, In: Leukemia and Lymphoma. 54, 9, p. 1867-1675 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  65. Published

    Tubulointerstitial Nephritis in a Patient With Probable Autoimmune Lymphoproliferative Syndrome

    Glerup, M., Herlin, T., Rittig, S., Grønbæk, Kirsten, Hokland, M. & Hasle, H., 2013, In: Journal of Pediatric Hematology/Oncology. 35, 5, p. e187-e189 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. 2012
  67. Published

    Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms

    Andersen, Christen Bertel L, Grønbæk, Kirsten & Hasselbalch, Hans Carl, 1 Apr 2012, In: Leukemia Research. 36, 4, p. 485-487 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

    Treppendahl, M. B., Qiu, X., Søgaard, A., Yang, X., Nandrup-Bus, C., Hother, C., Andersen, M. K., Kjeldsen, L., Möllgård, L., Möllgaard, L., Hellström-Lindberg, E., Jendholm, L. J., Porse, Bo Torben, Jones, P. A., Liang, G. & Grønbæk, Kirsten, 5 Jan 2012, In: Blood. 119, 1, p. 206-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. 2011
  70. Published

    Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL)

    Ralfkiaer, U., Hagedorn, P., Bangsgaard, N., Løvendorf, M. B., Ahler, C. B., Svensson, L., Kopp, K. L., Vennegaard, M. T., Lauenborg, B., Zibert, J. R., Krejsgaard, T., Bonefeld, C. M., Søkilde, R., Gjerdrum, L. M., Labuda, T., Mathiesen, A-M., Grønbaek, K., Wasik, M. A., Sokolowska-Wojdylo, M., Queille-Roussel, C. & 9 others, Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Litman, Thomas, Woetmann, Anders , Glue, C., Røpke, M. A., Skov, Lone & Ødum, Niels, 2011, In: Blood. 118, 22, p. 5891-5900 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    miR-449 inhibits cell proliferation and is down-regulated in gastric cancer

    Bou Kheir, T., Futoma-Kazmierczak, E., Jacobsen, A., Krogh, Anders, Bardram, L., Hother, C., Grønbæk, Kirsten, Federspiel, B., Lund, Anders H. & Friis-Hansen, Lennart Jan, 2011, In: Molecular Cancer. 10, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. 2010
  73. Published

    Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome

    Qiu, X., Hother, C., Ralfkiær, U. M., Søgaard, A., Lu, Q., Workman, C., Liang, G., Jones, P. A. & Grønbæk, Kirsten, 1 Jan 2010, In: P L o S One. 5, 9, p. e12994

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells

    Eriksen, K. W., Woetmann, Anders , Skov, Lone, Krejsgaard, T., Bovin, L. F., Hansen, M. L., Grønbæk, Kirsten, Billestrup, Nils, Nissen, Mogens Holst, Geisler, Carsten, Wasik, M. A. & Ødum, Niels, 2010, In: Journal of Investigative Dermatology. 130, 6, p. 1590-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Resistant Stat3 Activation and Proliferation in Cutaneous T-Cell Lymphoma

    Krejsgaard, T., Helvad, R., Ralfkiær, E., Astvad, K., Grønbæk, Kirsten, Eriksen, K. W., Geisler, C., Kopp, K., Zhang, Q., Ødum, N. & Woetmann, A., 2010, In: The Open Leukemia Journal. 3, 7, p. 9-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. 2009
  77. Published

    Cancer risk in long-term users of valproate: a population-based case-control study

    Hallas, J., Friis, S., Bjerrum, Lars, Støvring, H., Narverud, S. F., Heyerdahl, T., Grønbæk, Kirsten & Andersen, M., 2009, In: Cancer Epidemiology, Biomarkers & Prevention. 18, 6, p. 1714-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Splenectomy in two children with autoimmune lymphoproliferative syndrome and massive splenomegaly

    Glerup, M., Thelle, T., Grønbæk, Kirsten & Hasle, H., 2009, In: Pediatric Blood & Cancer. 53, 6, p. 1124-6 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. 2008
  80. Published

    A novel splice mutation in the TP53 gene associated with Leydig cell tumor and primitive neuroectodermal tumor

    Stecher, C. W., Hasle, H. & Grønbæk, Kirsten, 2008, In: Pediatric Blood & Cancer. 50, 3, p. 701-703 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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