Kim Theilgaard-Mønch
Clinical Associate Professor, Group leader
Department of Clinical Medicine
Blegdamsvej 9, 2100 København Ø
Theilgaard Group
Ole Maaløes Vej 5
2200 København N.
Member of:
- 2015
- Published
Cellular origin of prognostic chromosomal aberrations in AML patients
Mora-Jensen, H., Jendholm, L. J., Rapin, N. P. J., Andersen, M. K., Roug, A. S., Bagger, F. O., Bullinger, L., Winther, Ole, Borregaard, N., Porse, Bo Torben & Theilgaard-Mønch, Kim, 11 Feb 2015, In: Leukemia. 29, p. 1785-1789 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation
Knudsen, K. J., Rehn, M. C., Hasemann, M. S., Rapin, N. P. J., Bagger, F. O., Ohlsson, E. K., Willer, A., Frank, Anne-Katrine, Søndergaard, E., Jendholm, L. J., Thorén, L. A. M., Lee, J., Rak, J., Theilgaard-Mønch, Kim & Porse, Bo Torben, 2015, In: Genes & Development. 29, p. 1915-1929 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
New potential agents for cryopreservation of hematopoietic and adipose stromal cells
Svalgaard, J., Haastrup, E., Brink, A., Clausen, C., Holst, Birgitte, Theilgaard-Mønch, Kim, Reckzeh, K. & Fischer-Nielsen, A., Apr 2014, In: Cytotherapy. 16, Supplement 4, p. S58Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients
Rapin, N. P. J., Bagger, F. O., Jendholm, L. J., Mora-Jensen, H., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 6 Feb 2014, In: Blood (online). 123, 6, p. 894-904 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential expression of granulopoiesis related genes in neutrophil subsets distinguished by membrane expression of CD177
Hu, N., Mora-Jensen, H., Theilgaard-Mønch, Kim, Doornbos-van der Meer, B., Huitema, M. G., Stegeman, C. A., Heeringa, P., Kallenberg, C. G. M. & Westra, J., 2014, In: PLOS ONE. 9, 6, p. e99671 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Thorén, L. A. M., Jendholm, L. J., Winther, Ole & Porse, Bo Torben, 2013, In: Nucleic Acids Research. 41, Database issue, p. D1034-D1039 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving The Analysis Of Gene Expression Profiles By Comparing AML Blasts With Their Nearest Normal Counterparts
Rapin, N., Bagger, F. O., Jendholm, J., Mora-Jensen, H. I., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 2013, In: Blood. 122, 21Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
MicroRNA profiling in human neutrophils during bone marrow granulopoiesis and in vivo exudation
Larsen, M. T., Hother, C., Häger, M., Pedersen, C. C., Theilgaard-Mønch, Kim, Borregaard, N. & Cowland, J. B., 2013, In: P L o S One. 8, 3, 13 p., e58454.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis
Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Jendholm, L. J., Winther, O. & Porse, Bo Torben, 2012, In: Blood. 119, 26, p. 6394-6395 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Phosphorylation of Serine 248 of C/EBPa Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency
Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Theilgaard-Mønch, Kim, Pedersen, T. Å., Nerlov, C. & Porse, Bo Torben, 2012, In: P L o S One. 7, 6, p. e38841Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Immunophenotypical characterization of human neutrophil differentiation
Jensen, H. M., Jendholm, J., Fossum, A., Porse, Bo Torben, Borregaad, N. & Theilgaard-Mønch, Kim, 7 Jun 2011, In: Journal of Leukocyte Biology. p. 629-634 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hematopoietic Stem Cell Biology, Series Stem Cell Biology and Regenerative Medicine, Humana Press, New York, USA, 1st Edn 2010. ISBN 978-160327-346-6: Book Review
Theilgaard-Mønch, Kim, Jan 2011, In: European Journal of Haematology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression profiling in MDS and AML: potential and future avenues
Theilgaard-Mönch, K., Boultwood, J., Ferrari, S., Giannopoulos, K., Hernandez-Rivas, J. M., Kohlmann, A., Morgan, M., Porse, B., Tagliafico, E., Zwaan, C. M., Wainscoat, J., Van den Heuvel-Eibrink, M. M., Mills, K., Bullinger, L., Theilgaard-Mönch, K., Boultwood, J., Ferrari, S., Giannopoulos, K., Hernandez-Rivas, J. M., Kohlmann, A. & 8 others, , 2011, In: Leukemia. 25, 6, p. 909-20 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia
Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Hematopoietic Stem Cell Protocols
Theilgaard-Mønch, Kim, 2008, In: European Journal of Haematology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO).
Kirkeby, Agnete, Torup, L., Bochsen, L., Kjalke, M., Abel, K., Theilgaard-Mønch, Kim, Johansson, P. I., Bjørn, S. E., Gerwien, J. & Leist, M., 2008, In: Thrombosis and Haemostasis. 99, 4, p. 720-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Kirstetter, P., Schuster, Mikkel Bruhn, Bereshchenko, O., Moore, S., Dvinge, H., Kurz, E., Theilgaard-Mønch, Kim, Månsson, R., Pedersen, T. A., Pabst, T., Schrock, E., Porse, Bo Torben, Jacobsen, S. E. W., Bertone, P., Tenen, D. G. & Nerlov, C., 2008, In: Cancer Cell. 13, 4, p. 299-310 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.
Hasemann, M. S., Damgaard, I., Schuster, Mikkel Bruhn, Theilgaard-Mønch, Kim, Sørensen, A. B., Mrsic, A., Krugers, T., Ylstra, B., Pedersen, F. S., Nerlov, C. & Porse, Bo Torben, 2008, In: Blood. 111, 8, p. 4309-21 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
Weischenfeldt, Joachim Lütken, Damgaard, I., Bryder, D., Theilgaard-Mønch, Kim, Thoren, L. A., Nielsen, F. C., Jacobsen, S. E. W., Nerlov, C. & Porse, Bo Torben, 2008, In: Genes & Development. 22, 10, p. 1381-96 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.
Jacobsen, L. C., Sørensen, O. E., Cowland, J. B., Borregaard, N. & Theilgaard-Mønch, Kim, 2008, In: Journal of Leukocyte Biology. 83, 5, p. 1155-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
Jacobsen, L. C., Theilgaard-Mønch, Kim, Christensen, E. I. & Borregaard, N., 2007, In: Blood. 109, 7, p. 3084-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Neutrophil granules: a library of innate immunity proteins.
Borregaard, N., Sørensen, O. E. & Theilgaard-Mønch, Kim, 2007, In: Trends in Immunology. 28, 8, p. 340-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Bracken, A. P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Mønch, Kim, Minucci, S., Porse, Bo Torben, Marine, J., Hansen, K. H. & Helin, K., 2007, In: Genes & Development. 21, 5, p. 525-30 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes.
Nilsson, L., Edén, P., Olsson, E., Månsson, R., Astrand-Grundström, I., Strömbeck, B., Theilgaard-Mønch, Kim, Anderson, K., Hast, R., Hellström-Lindberg, E., Samuelsson, J., Bergh, G., Nerlov, C., Johansson, B., Sigvardsson, M., Borg, A. & Jacobsen, S. E. W., 2007, In: Blood. 110, 8, p. 3005-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.
Theilgaard-Mønch, Kim, Jacobsen, L. C., Nielsen, M. J., Rasmussen, T., Udby, L., Gharib, M., Arkwright, P. D., Gombart, A. F., Calafat, J., Moestrup, S. K., Porse, Bo Torben & Borregaard, N., 2006, In: Blood. 108, 1, p. 353-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3997971
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HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Research output: Contribution to journal › Journal article › Research › peer-review
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Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML
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Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
Research output: Contribution to journal › Journal article › Research › peer-review
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