Ivan Vogelius

Ivan Vogelius

Clinical Professor


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  1. 2024
  2. Published

    MR-guided stereotactic radiotherapy of infra-diaphragmatic oligometastases: Evaluation of toxicity and dosimetric parameters

    van Overeem Felter, M., Møller, P. K., Josipovic, Mirjana, Bekke, S. N., Bernchou, U., Serup-Hansen, E., Madsen, K., Parikh, P. J., Kim, J., Geertsen, P., Behrens, C. P., Vogelius, Ivan R. , Pøhl, M., Schytte, T. & Persson, Gitte F., 2024, In: Radiotherapy and Oncology. 192, 110090.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Machine learning applied in patient-reported outcome research—exploring symptoms in adjuvant treatment of breast cancer

    Pappot, Helle, Björnsson, B. P., Krause, Oswin, Bæksted, C., Bidstrup, Pernille Envold Hansen, Dalton, Susanne Oksbjerg, Johansen, Christoffer, Knoop, A., Vogelius, Ivan R. & Holländer-Mieritz, C., 2024, In: Breast Cancer. 31, p. 148–153 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2023
  5. Published

    Explicit Temporal Embedding in Deep Generative Latent Models for Longitudinal Medical Image Synthesis

    Schön, Julian Elisha, Selvan, Raghav, Nygård, L., Vogelius, Ivan R. & Petersen, Jens, 13 Jan 2023, arxiv.org.

    Research output: Working paper › Preprint › Research

  6. Published

    A comparison of loco-regional relapse pattern in HPV positive vs negative oropharyngeal cancers following radiotherapy: relation to pretreatment FDG-PET and radiotherapy target volumes

    Håkansson, K., Lindegaard, A. M., Bernsdorf, M., Gothelf, A., Kristensen, C. A., Specht, Lena, Friborg, Jeppe Tang & Vogelius, Ivan R. , 2023, In: Acta Oncologica. 62, 9, p. 1028-1035 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A systematic review on clinical adaptive radiotherapy for head and neck cancer

    Lindegaard, A. M., Håkansson, K., Bernsdorf, M., Gothelf, A. B., Kristensen, C. A., Specht, Lena, Vogelius, Ivan R. & Friborg, Jeppe Tang, 2023, In: Acta oncologica (Stockholm, Sweden). 62, 11, p. 1360-1368 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    CBCT-based online adaptive radiotherapy for head and neck cancer - dosimetric evaluation of first clinical experience

    Håkansson, K., Giannoulis, E., Lindegaard, A., Friborg, J. & Vogelius, Ivan R. , 2023, In: Acta oncologica (Stockholm, Sweden). 62, 11, p. 1369-1374 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Evaluating the dosimetric effect of intra-fractional variations in deep inspiration breath-hold radiotherapy - a proof-of-concept study

    Håkansson, K., Josipovic, Mirjana, Ottosson, W., Behrens, C. P., Vogelius, Ivan R. & Persson, Gitte F., 2023, In: Acta oncologica (Stockholm, Sweden). 62, 10, p. 1246-1250 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Interfractional dose accumulation for MR-guided liver SBRT: Variation among algorithms is highly patient- and fraction-dependent

    Wahlstedt, I., Smith, Abraham George, Andersen, C. E., Behrens, C. P., Nørring Bekke, S., Boye, K., van Overeem Felter, M., Josipovic, Mirjana, Petersen, Jens, Risumlund, S. L., Tascón-Vidarte, J. D., van Timmeren, J. E. & Vogelius, Ivan R. , 2023, In: Radiotherapy and Oncology. 182, 9 p., 109448.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Interim analysis of patient-reported outcome compliance and dosimetry in a phase 3 randomized clinical trial of oesophagus-sparing spinal radiotherapy

    Nielsen, A. M., Storm, K. S., Laursen, M. R. T., Gram, V. R., Rechner, L. A., Ottosson, W., Suppli, M. H., Sibolt, P., Behrens, C. F., Vogelius, Ivan R. & Persson, Gitte F., 2023, In: Acta oncologica (Stockholm, Sweden). 62, 11, p. 1496-1501 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Prediction of Radiation-induced Lymphopenia following Exposure of the Thoracic Region and Associated Risk of Infections and Mortality

    Terrones-Campos, C., Ledergerber, B., Forbes, N., Smith, Abraham George, Petersen, Jens, Helleberg, Marie, Lundgren, Jens, Specht, Lena & Vogelius, Ivan R. , 2023, In: Clinical Oncology. 35, 7, p. e434-e444 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The potential for local ablative therapy of oligometastases in head and neck squamous cell carcinoma: a real-world data analysis

    Kjems, J., Laursen, M. R. T., Kristensen, C. A., Gothelf, A. B., Bernsdorf, M., Specht, Lena, Berthelsen, A. K., Vogelius, Ivan R. , Persson, Gitte F. & Friborg, Jeppe Tang, 2023, In: Acta Oncologica. 62, 9, p. 1091-1095

    Research output: Contribution to journal › Letter › Research › peer-review

  14. Published

    Tumor volume definitions in head and neck squamous cell carcinoma – Comparing PET/MRI and histopathology

    Terzidis, E., Friborg, Jeppe Tang, Vogelius, Ivan R. , Lelkaitis, G., von Buchwald, Christian, Olin, A. B., Johannesen, H. H., Fischer, Barbara Malene Bjerregaard, Wessel, Irene & Rasmussen, Jacob Høygaard, 2023, In: Radiotherapy and Oncology. 180, 109484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Using and Understanding Survival Statistics - or How We Learned to Stop Worrying and Love the Kaplan-Meier Estimate

    Bentzen, S. M. & Vogelius, Ivan R. , 2023, In: International Journal of Radiation Oncology Biology Physics. 115, 4, p. 839-846 8 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  16. 2022
  17. Published

    Accuracy and consistency of intensity-based deformable image registration in 4DCT for tumor motion estimation in liver radiotherapy planning

    Tascon-Vidarte, J. D., Stick, L. B., Josipovic, Mirjana, Risum, S., Jomier, J., Erleben, Kenny, Vogelius, Ivan R. & Darkner, Sune, Jul 2022, In: PLoS ONE. 17, 7 July, p. 1-15 e0271064.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Early non-cancer mortality risk prediction after curative-intent radiotherapy or chemoradiotherapy for head and neck squamous cell carcinoma

    Jensen, K. H., Vogelius, Ivan R. , Bernsdorf, M., Gothelf, A., Kristensen, C. A., Maare, C., Andersen, E., Specht, Lena & Friborg, Jeppe Tang, Jun 2022, In: Radiotherapy and Oncology. 171, p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Proton vs photon radiation therapy for glioblastoma: Maximizing information from trial

    Vogelius, Ivan R. & Bentzen, S. M., 4 May 2022, In: Neuro-Oncology. 24, 5, p. 849-850 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  20. Published

    Radiation-Induced Toxicity Risks in Photon Versus Proton Therapy for Synchronous Bilateral Breast Cancer

    Stick, L. B., Jensen, M. F., Bentzen, S. M., Kamby, C., Lundgaard, A. Y., Maraldo, M. V., Offersen, B. V., Yu, J. & Vogelius, Ivan R. , 13 Mar 2022, In: International Journal of Particle Therapy. 8, 4, p. 1-13 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Gating has a negligible impact on dose delivered in MRI-guided online adaptive radiotherapy of prostate cancer

    Wahlstedt, I., Andratschke, N., Behrens, C. P., Ehrbar, S., Gabryś, H. S., Schüler, H. G., Guckenberger, M., Smith, Abraham George, Tanadini-Lang, S., Tascón-Vidarte, J. D., Vogelius, Ivan R. & van Timmeren, J. E., 2022, In: Radiotherapy and Oncology. 170, p. 205-212

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Gating has small impact on dose to OARs and PTV coverage in MR-guided daily ART of prostate cancer

    Wahlstedt, I., Andratschke, N., Behrens, C. P., Ehrbar, S., Gabrys, H. S., Schueler, H. G., Guckenberger, M., Smith, Abraham George, Tanadini-Lang, S., Tascon-Vidarte, J. D., Vogelius, Ivan R. & van Timmeren, J. E., 2022, In: Radiotherapy and Oncology. 170, p. S15-S16

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. Published

    Risk of Bacterial, Viral, and Fungal Infections in Patients With Solid Malignant Tumors Treated With Curative Intent Radiation Therapy

    Terrones-Campos, C., Ledergerber, B., Specht, Lena, Vogelius, Ivan R. , Helleberg, M. & Lundgren, Jens, 2022, In: Advances in Radiation Oncology. 7, 6, 16 p., 100950.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Robust extraction of biological information from diffusion-weighted magnetic resonance imaging during radiotherapy using semi-automatic delineation

    Bisgaard, A. L. H., Brink, C., Fransen, M. L., Schytte, T., Behrens, C. P., Vogelius, Ivan R. , Nissen, H. D. & Mahmood, F., 2022, In: Physics and Imaging in Radiation Oncology. 21, p. 146-152 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Time-resolved plastic scintillator dosimetry in MR linear accelerators without image distortion

    Klavsen, M. F., Ankjærgaard, C., Behrens, C. P., Vogelius, Ivan R. , Boye, K., Hansen, Rasmus Hvass & Andersen, C. E., 2022, In: Radiation Measurements. 154, 106759.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2021
  27. Published

    A framework for voxel-based assessment of biological effect after proton radiotherapy in pediatric brain cancer patients using multi-modal imaging

    Skaarup, M., Lundemann, M. J., Darkner, Sune, Jorgensen, M., Marner, Lisbeth, Mirkovic, D., Grosshans, D., Peeler, C., Mohan, R., Vogelius, Ivan R. & Appelt, A., 10 Jun 2021, In: Medical Physics. 48, 7, 12 p., 4110-4121.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Intratumor heterogeneity is biomarker specific and challenges the association with heterogeneity in multimodal functional imaging in head and neck squamous cell carcinoma

    Rasmussen, J. H., Olin, A. B., Lelkaitis, G., Hansen, Adam Espe, Andersen, Flemming Littrup, Johannesen, H. H., Kjær, Andreas, Fischer, Barbara Malene Bjerregaard, Specht, Lena, Bentzen, S. M., von Buchwald, Christian, Wessel, Irene & Vogelius, Ivan R. , Jun 2021, In: European Journal of Radiology. 139, 8 p., 109668.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    A randomized phase 2 trial of first-line docetaxel, carboplatin, capecitabine (CTX) and epirubicin, oxaliplatin, capecitabine (EOX) in advanced esophagogastric adenocarcinoma

    Petersen, P. C., Petersen, L. N., Vogelius, Ivan R. , Bjerregaard, J. K. & Baeksgaard, L., 2021, In: Acta Oncologica. 60, 7, p. 948-953 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Bloodstream infections in head and neck cancer patients after curative-intent radiotherapy: a population-based study from the Danish Head and Neck Cancer Group database

    Jensen, K. H., Vogelius, Ivan R. , Moser, Claus Ernst, Andersen, E., Eriksen, J. G., Johansen, J., Farhadi, M., Andersen, M., Overgaard, J. & Friborg, Jeppe Tang, 2021, In: British Journal of Cancer. 125, p. 458-464 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Cine-MRI Simulation to Evaluate Tumor Tracking

    Tascón-Vidarte, J. D., Wahlstedt, I., Jomier, J., Erleben, Kenny, Vogelius, Ivan R. & Darkner, Sune, 2021, Simulation and Synthesis in Medical Imaging - 6th International Workshop, SASHIMI 2021, Held in Conjunction with MICCAI 2021, Proceedings. Svoboda, D., Burgos, N., Wolterink, J. M. & Zhao, C. (eds.). Springer, p. 131-141 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol. 12965 LNCS).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  32. Published

    Distant metastases in squamous cell carcinoma of the pharynx and larynx: a population-based DAHANCA study

    Kjems, J., Zukauskaite, R., Johansen, J., Eriksen, J. G., Lassen, P., Andersen, E., Andersen, M., Farhadi, M., Overgaard, J., Vogelius, Ivan R. & Friborg, Jeppe Tang, 2021, In: Acta Oncologica. 60, 11, p. 1472-1480 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Early Mortality after Radical Radiotherapy in Head and Neck Cancer: A Nationwide Analysis from the Danish Head and Neck Cancer Group (DAHANCA) Database

    Jensen, K. H., Vogelius, Ivan R. , Kristensen, C. A., Andersen, E., Overgaard, J., Eriksen, J. G., Primdahl, H., Johansen, J., Farhadi, M., Andersen, M. & Friborg, Jeppe Tang, 2021, In: Clinical Oncology. 33, 1, p. 57-63 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Novel technologies in radiotherapy in the Nordic countries - report from the NACP2020/21 conference

    Korreman, S. S., Vogelius, Ivan R. , Abdi, A. J., Hansen, S. B. & Behrens, C. P., 2021, In: Acta Oncologica. 60, 11, p. 1383-1385 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  35. Published

    Outcome-based multiobjective optimization of lymphoma radiation therapy plans

    Modiri, A., Vogelius, Ivan R. , Ann Rechner, L., Nygård, L., Bentzen, S. M. & Specht, Lena, 2021, In: British Journal of Radiology. 94, 1127, 20210303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Robustness and Generalizability of Deep Learning Synthetic Computed Tomography for Positron Emission Tomography/Magnetic Resonance Imaging–Based Radiation Therapy Planning of Patients With Head and Neck Cancer

    Olin, A. B., Thomas, C., Hansen, Adam Espe, Rasmussen, J. H., Krokos, G., Urbano, T. G., Michaelidou, A., Jakoby, B., Ladefoged, C. N., Berthelsen, A. K., Håkansson, K., Vogelius, Ivan R. , Specht, Lena, Barrington, S. F., Andersen, Flemming Littrup & Fischer, Barbara Malene Bjerregaard, 2021, In: Advances in Radiation Oncology. 6, 6, 100762.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Using biometric sensor data to monitor cancer patients during radiotherapy: Protocol for the OncoWatch feasibility study

    Holländer-Mieritz, C., Vogelius, Ivan R. , Kristensen, C. A., Green, A., Rindum, J. L. & Pappot, Helle, 2021, In: JMIR Research Protocols. 10, 5, 5 p., e26096.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2020
  39. Published

    In Reply to Berk and Alfonso

    Vogelius, Ivan R. & Bentzen, S. M., 1 Nov 2020, In: International Journal of Radiation Oncology, Biology, Physics. 108, 3, p. 834-835 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  40. Published

    Involved node radiation therapy in the combined modality treatment for early-stage Hodgkin lymphoma: Analysis of relapse location and long-term outcome

    Nielsen, K., Maraldo, M. V., Berthelsen, A. K., Loft, A., Brown, Peter de Nully, Vogelius, Ivan R. , Petersen, P. M. & Specht, Lena, 1 Sep 2020, In: Radiotherapy and Oncology. 150, p. 236-244 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Intrafractional fiducial marker position variations in stereotactic liver radiotherapy during voluntary deep inspiration breath-hold.

    Stick, L. B., Vogelius, Ivan R. , Risum, S. N. & Josipovic, Mirjana, 28 Aug 2020, In: British Journal of Radiology. 93, 7 p., 20200859.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Does multiparametric imaging with 18F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?

    Rasmussen, J. H., Olin, A., Lelkaitis, G., Hansen, Adam Espe, Andersen, Flemming Littrup, Johannesen, H. H., Kjær, Andreas, Vogelius, Ivan R. , Specht, Lena, Bentzen, S. M., Wessel, I., von Buchwald, Christian & Fischer, Barbara Malene Bjerregaard, Jul 2020, In: British Journal of Cancer. 123, 1, p. 46-53 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Systematic use of patient reported outcome during radiotherapy for head and neck cancer: study protocol for the national DAHANCA 38 trial

    Holländer-mieritz, C., Johansen, J., Taarnhøj, G. A., Johansen, Christoffer, Vogelius, Ivan R. , Kristensen, C. A. & Pappot, Helle, 3 May 2020, In: Acta Oncologica. 59, 5, p. 603-607 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  44. Published

    Biological optimization for mediastinal lymphoma radiotherapy - a preliminary study

    Rechner, L. A., Modiri, A., Stick, L. B., Maraldo, M. V., Aznar, M. C., Rice, S. R., Sawant, A., Bentzen, S. M., Vogelius, Ivan R. & Specht, Lena, 27 Mar 2020, In: Acta Oncologica. 59, 8, p. 879-887 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Analysis of early respiratory-related mortality after radiation therapy of non-small-cell lung cancer: feasibility of automatic data extraction for dose–response studies

    Stervik, L., Pettersson, N., Scherman, J., Behrens, C. F., Ceberg, C., Engelholm, S., Gunnarsson, K., Hallqvist, A., Nyman, J., Persson, Gitte F., Pøhl, M., Wahlstedt, I., Vogelius, Ivan R. & Bäck, A., Mar 2020, In: Acta Oncologica. 59, 6, p. 628-635

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Heterogeneity in tumours: Validating the use of radiomic features on 18F-FDG PET/CT scans of lung cancer patients as a prognostic tool

    Krarup, M. M. K., Nygård, L., Vogelius, Ivan R. , Andersen, F. L., Cook, G., Goh, V. & Fischer, B. M., Mar 2020, In: Radiotherapy and Oncology. 144, p. 72-78

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Circulating cell free DNA during definitive chemo-radiotherapy in non-small cell lung cancer patients - initial observations

    Nygård, L., Ahlborn, L. B., Persson, Gitte F., Chandrananda, D., Langer, J. W., Fischer, Barbara Malene Bjerregaard, Langer, Seppo W., Gabrielaite, M., Kjær, Andreas, Rosenfeld, N., Mouliere, F., Østrup, O., Vogelius, Ivan R. & Bentzen, S. M., 2020, In: PLoS ONE. 15, 4, 12 p., e0231884.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Deep learning for identification of critical regions associated with toxicities after liver stereotactic body radiation therapy

    Ibragimov, Bulat, Toesca, D. A. S., Chang, D. T., Yuan, Y., Koong, A. C., Xing, L. & Vogelius, Ivan R. , 2020, In: Medical Physics. 47, 8, p. 3721-3731

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Diminishing Returns From Ultrahypofractionated Radiation Therapy for Prostate Cancer

    Vogelius, Ivan R. & Bentzen, S. M., 2020, In: International Journal of Radiation Oncology Biology Physics. 107, 2, p. 299-304 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Feasibility of Multiparametric Positron Emission Tomography/Magnetic Resonance Imaging as a One-Stop Shop for Radiation Therapy Planning for Patients with Head and Neck Cancer

    Olin, A. B., Hansen, Adam Espe, Rasmussen, J. H., Ladefoged, C. N., Berthelsen, A. K., Håkansson, K., Vogelius, Ivan R. , Specht, Lena, Gothelf, A. B., Kjær, Andreas, Fischer, Barbara Malene Bjerregaard & Andersen, Flemming Littrup, 2020, In: International Journal of Radiation Oncology Biology Physics. 108, 5, p. 1329-1338 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Harnessing data science to advance radiation oncology

    Vogelius, Ivan R. , Petersen, Jens & Bentzen, S. M., 2020, In: Molecular Oncology. 14, 7, p. 1514–1528

    Research output: Contribution to journal › Review › Research › peer-review

  52. Published

    High nodal FDG uptake increases risk of distant metastasis in patients with oropharyngeal squamous cell carcinoma

    Jensen, J. S., Christensen, J. T., Håkansson, K., Zamani, M., Vogelius, Ivan R. , Löfgren, J., Fischer, B. M., Friborg, Jeppe Tang, von Buchwald, Christian & Rasmussen, J. H., 2020, In: European Journal of Nuclear Medicine and Molecular Imaging. 47, p. 1039–1045

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    ILROG emergency guidelines for radiation therapy of hematological malignancies during the COVID-19 pandemic

    Yahalom, J., Dabaja, B. S., Ricardi, U., Ng, A., Mikhaeel, N. G., Vogelius, Ivan R. , Illidge, T., Qi, S., Wirth, A. & Specht, Lena, 2020, In: Blood. 135, 21, p. 1829-1832 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Multiple Testing, Cut-Point Optimization, and Signs of Publication Bias in Prognostic FDG-PET Imaging Studies of Head and Neck and Lung Cancer: A Review and Meta-Analysis

    Clausen, Malene Martini, Vogelius, Ivan R. , Kjær, Andreas & Bentzen, S. M., 2020, In: Diagnostics. 10, 12, 17 p., 1030.

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Outcome in patients with isolated regional recurrence after primary radiotherapy for head and neck cancer

    Lindegaard, A. M., von Buchwald, Christian, Rasmussen, J. H., Specht, Lena, Vogelius, Ivan R. , Zamani, M., Woller, N. C., Lelkaitis, G. & Friborg, Jeppe Tang, 2020, In: Head and Neck. 42, 11, p. 3161-3170

    Research output: Contribution to journal › Journal article › Research › peer-review

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