Jens Benn Sørensen
Clinical Associate Professor
- 2024
- Published
UV1 telomerase vaccine with ipilimumab and nivolumab as second line treatment for pleural mesothelioma – A phase II randomised trial
Haakensen, V. D., Öjlert, Å. K., Thunold, S., Farooqi, S., Nowak, A. K., Chin, W. L., Grundberg, O., Szejniuk, W. M., Cedres, S., Sørensen, Jens Benn, Dalen, T. S., Lund-Iversen, M., Bjaanæs, M. & Helland, Å., 2024, In: European Journal of Cancer. 202, 6 p., 113973.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Artificial Intelligence for Automated DWI/FLAIR Mismatch Assessment on Magnetic Resonance Imaging in Stroke: A Systematic Review
Offersen, C. M., Sørensen, Jens Benn, Sheng, K., Carlsen, Jonathan Frederik, Langkilde, Annika Reynberg, Pai, A., Truelsen, Thomas Clement & Nielsen, Michael Bachmann, 2023, In: Diagnostics. 13, 12, 15 p., 2111.Research output: Contribution to journal › Review › Research › peer-review
- Published
Efficacy of Brigatinib After Progression on Alectinib or Ceritinib: Does One Drug Work in a Pretreated Heterogeneous ALK-Positive NSCLC Population?
Urbanska, E. M., Sørensen, Jens Benn & Santoni Rugiu, Eric, 2023, In: Journal of Thoracic Oncology. 18, 3, p. e28-e29Research output: Contribution to journal › Letter › Research › peer-review
- Published
New pathogenic germline variants identified in mesothelioma
Belcaid, L., Bertelsen, B., Wadt, Karin Anna Wallentin, Tuxen, I., Spanggaard, I., Højgaard, M., Sørensen, Jens Benn, Ravn, J., Lassen, Ulrik Niels, Nielsen, Finn Cilius, Rohrberg, K. & Westmose Yde, C., 2023, In: Lung Cancer. 179, 8 p., 107172.Research output: Contribution to journal › Review › Research › peer-review
- Published
Real-World Data on Combined EGFR-TKI and Crizotinib Treatment for Acquired and De Novo MET Amplification in Patients with Metastatic EGFR-Mutated NSCLC
Urbanska, E. M., Grauslund, M., Koffeldt, P. R., Truelsen, S. L. B., Löfgren, J. O., Costa, J. C., Melchior, L. C., Sørensen, Jens Benn & Santoni Rugiu, Eric, 2023, In: International Journal of Molecular Sciences. 24, 17, 25 p., 13077.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Clinical features affecting efficacy of immune checkpoint inhibitors in pretreated patients with advanced NSCLC: a Danish nationwide real-world study
Mouritzen, M. T., Junker, K. F., Carus, A., Ladekarl, M., Meldgaard, P., Nielsen, A. W. M., Livbjerg, A., Larsen, J. W., Skuladottir, H., Kristiansen, C., Wedervang, K., Schytte, T., Hansen, K. H., Østby, A-C., Frank, M. S., Lauritsen, J., Sørensen, J. B., Langer, S. W., Persson, G. F., Andersen, J. L. & 7 others, , 2022, In: Acta Oncologica. 61, 4, p. 409-416Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Durable Response to Combined Osimertinib and Pralsetinib Treatment for Osimertinib Resistance Due to Novel Intergenic ANK3-RET Fusion in EGFR-Mutated Non–Small-Cell Lung Cancer
Urbanska, E. M., Sørensen, Jens Benn, Melchior, L. C., Costa, J. C. & Santoni Rugiu, Eric, 2022, In: JCO Precision Oncology. 6, 6, 6 p., e2200040.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Initial treatment and survival in Danish patients diagnosed with non-small-cell lung cancer (2005-2015): SCAN-LEAF study
Sørensen, Jens Benn, Horvat, P., Rosenlund, M., Kejs, A. M., Patel, D., Juarez-Garcia, A., Lacoin, L., Daumont, M. J., Penrod, J. R., O'donnell, J. C., Brustugun, O. T. & Ekman, S., 2022, In: Future Oncology. 18, 2, p. 205-214 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Correlation of MET-receptor overexpression with MET gene amplification and patient outcome in malignant mesothelioma
Santoni Rugiu, Eric, Lü, M. J. S., Jakobsen, J. N., Melchior, L. C., Ravn, J. & Sørensen, Jens Benn, 2021, In: International Journal of Molecular Sciences. 22, 23, 20 p., 12868.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intracranial Response of ALK+ Non-Small-cell Lung Cancer to Second-line Dose-escalated Brigatinib After Alectinib Discontinuation Due to Drug-induced Hepatitis and Relapse After Whole Brain Radiotherapy Followed by Stereotactic Radiosurgery
Urbanska, E. M., Santoni Rugiu, Eric, Melchior, L. C., Carlsen, Jonathan Frederik & Sørensen, Jens Benn, 2021, In: Clinical Lung Cancer. 22, 4, p. e528-e532 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intracranial effect of osimertinib in relapsed EGFR-mutated T790M-positive and -negative non-small cell lung cancer patients: results from a phase II study
Eide, I. J. Z., Grut, H., Helland, Å., Ekman, S., Sørensen, Jens Benn, Hansen, K. H., Grønberg, B. H., Cicenas, S., Koivunen, J. P., Mellemgaard, A. & Brustugun, O. T., 2021, In: Acta Oncologica. 60, 12, p. 1565-1571 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nationwide survival benefit after implementation of first-line immunotherapy for patients with advanced nsclc—real world efficacy
Mouritzen, M. T., Carus, A., Ladekarl, M., Meldgaard, P., Nielsen, A. W. M., Livbjerg, A., Larsen, J. W., Skuladottir, H., Kristiansen, C., Wedervang, K., Schytte, T., Hansen, K. H., Østby, A. C., Frank, M. S., Lauritsen, J., Sørensen, J. B., Langer, S. W., Persson, G. F., Andersen, J. L., Frary, J. M. C. & 5 others, , 2021, In: Cancers. 13, 19, 4846.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Treatment Algorithm for Advanced ALK-Rearranged NSCLC
Urbanska, E. M., Sørensen, Jens Benn & Santoni Rugiu, Eric, Sep 2020, In: Journal of Thoracic Oncology. 15, 9, p. e156-e157Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Changing ALK-TKI-Resistance Mechanisms in Rebiopsies of ALK-Rearranged NSCLC: ALK- and BRAF-Mutations Followed by Epithelial-Mesenchymal Transition
Urbanska, E. M., Sørensen, Jens Benn, Melchior, L. C., Costa, J. C. & Santoni Rugiu, Eric, 2020, In: International Journal of Molecular Sciences (Online). 21, 8, 12 p., 2847.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Intrinsic resistance to EGFR-Tyrosine Kinase Inhibitors in EGFR-Mutant Non-Small Cell Lung Cancer: Differences and Similarities with Acquired Resistance.
Santoni Rugiu, Eric, Melchior, L. C., Urbanska, E. M., Jakobsen, J. N., Stricker, K. D., Grauslund, M. & Sørensen, Jens Benn, 1 Jul 2019, In: Cancers. 11, 7, 923.Research output: Contribution to journal › Review › Research › peer-review
- Published
18F-FDG PET/CT Findings in Disseminated Genital Herpes in an Immunocompetent Patient With Anaplastic Lymphoma Kinase Rearranged Advanced Nonsmall Cell Lung Cancer
Dejanovic, D., Amtoft, A. G., Sørensen, Jens Benn & Pøhl, M., 2019, In: Clinical Nuclear Medicine. 44, 5, p. e351-e352Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nintedanib in combination with pemetrexed and cisplatin for chemotherapy-naive patients with advanced malignant pleural mesothelioma (LUME-Meso): a double-blind, randomised, placebo-controlled phase 3 trial
Scagliotti, G. V., Gaafar, R., Nowak, A. K., Nakano, T., van Meerbeeck, J., Popat, S., Vogelzang, N. J., Grosso, F., Aboelhassan, R., Jakopovic, M., Ceresoli, G. L., Taylor, P., Orlandi, F., Fennell, D. A., Novello, S., Scherpereel, A., Kuribayashi, K., Cedres, S., Sørensen, J. B., Pavlakis, N. & 6 others, , 2019, In: The Lancet Respiratory Medicine. 7, 7, p. 569-580 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Very Early Response Evaluation by PET/MR in Patients with Lung Cancer: Timing and Feasibility
Langer, N. H., Langer, Seppo W., Johannesen, H. H., Hansen, A. E., Costa, J., Klausen, T. L., Forman, Julie Lyng, Olin, A., Rasmussen, S. H., Sørensen, Jens Benn, Löfgren, J., Kjær, A. & Fischer, B. M., 2019, In: Diagnostics. 9, 1, 13 p., 35.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Molecular prediction of adjuvant cisplatin efficacy in Non-Small Cell Lung Cancer (NSCLC)—validation in two independent cohorts
Buhl, I. K., Santoni Rugiu, Eric, Ravn, J., Hansen, A., Christensen, I. J., Jensen, T., Pratt, B., Askaa, J., Jensen, P. B., Knudsen, S. & Sørensen, Jens Benn, 22 Mar 2018, In: PLOS ONE. 13, 3, 18 p., e0194609.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changing Resistance Mechanisms in Rebiopsies of ALK-Positive NSCLC During Multiple Lines of Therapy: ALK/BRAF-Mutations Followed By EMT
Urbanska, E., Melchior, L., De Stricker, K., Sørensen, Jens Benn & Rugiu, E. S., 2018, In: Journal of Thoracic Oncology. 13, 10, p. S946 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Concomitant driver mutations in advanced EGFR-mutated non-small-cell lung cancer and their impact on erlotinib treatment
Jakobsen, J. N., Santoni Rugiu, Eric, Grauslund, M., Melchior, L. & Sørensen, Jens Benn, 2018, In: OncoTarget. 9, 40, p. 26195-26208Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer
Gandhi, L., Rodríguez-Abreu, D., Gadgeel, S., Esteban, E., Felip, E., De Angelis, F., Domine, M., Clingan, P., Hochmair, M. J., Powell, S. F., Cheng, S. Y-S., Bischoff, H. G., Peled, N., Grossi, F., Jennens, R. R., Reck, M., Hui, R., Garon, E. B., Boyer, M., Rubio-Viqueira, B. & 19 others, , 2018, In: The New England Journal of Medicine. 378, 22, p. 2078-2092Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Concomitant Driver Mutations in Advanced Stage Non-Small-Cell Lung Cancer of Adenocarcinoma Subtype with Activating EGFR-Mutation
Sørensen, Jens Benn, Grauslund, M., Melchior, L., Jakobsen, J. N. & Santoni Rugiu, Eric, 2017, In: Journal of Thoracic Oncology. 12, S1, p. S518-S519Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Heterogeneous Resistance Mechanisms in Rebiopsies from EGFR-Mutated NSCLC: Transformation to SCLC; FGFR3 and T790M Mutations
Urbanska, E., Grauslund, M., Melchior, L., Sørensen, Jens Benn & Santoni Rugiu, Eric, 2017, In: Journal of Thoracic Oncology. 12, 11 - S2, p. S2203Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Heterogeneous resistance mechanisms in an EGFR exon 19-mutated non-small cell lung cancer patient treated with erlotinib: Persistent FGFR3-mutation, localized transformation to EGFR-mutated SCLC, and acquired T790M EGFR-mutation
Santoni Rugiu, Eric, Grauslund, M., Melchior, L. C., Costa, J. C., Sørensen, Jens Benn & Urbanska, E. M., 2017, In: Lung Cancer. 113, p. 14-17 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implementation of lung cancer CT screening in the Nordic countries
Pedersen, J. H., Sørensen, Jens Benn, Saghir, Z., Fløtten, Ø., Brustugun, O. T., Ashraf, H., Strand, T., Friesland, S., Koyi, H., Ek, L., Nyrén, S., Bergman, P., Jekunen, A., Nieminen, E. & Gudbjartsson, T., 2017, In: Acta Oncologica. 56, 10, p. 1249-1257Research output: Contribution to journal › Review › Research › peer-review
- Published
Nintedanib Plus Pemetrexed/Cisplatin in Patients With Malignant Pleural Mesothelioma: Phase II Results From the Randomized, Placebo-Controlled LUME-Meso Trial
Grosso, F., Steele, N., Novello, S., Nowak, A. K., Popat, S., Greillier, L., John, T., Leighl, N. B., Reck, M., Taylor, P., Planchard, D., Sørensen, Jens Benn, Socinski, M. A., von Wangenheim, U., Loembé, A. B., Barrueco, J., Morsli, N. & Scagliotti, G., 2017, In: Journal of Clinical Oncology. 35, 31, p. 3591-3600Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prevalence of ALK rearrangement in pulmonary adenocarcinomas in an unselected Caucasian population from a defined catchment area: impact of smoking
Skov, B. G., Clementsen, P., Larsen, Klaus Richter, Sørensen, Jens Benn & Mellemgaard, A., 2017, In: Histopathology. 70, 6, p. 889-895Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Prospective blinded evaluation predicting efficacy of adjuvant cisplatinum and vinorelbine by a multigene assay after radical surgery in non-small cell lung cancer
Buhl, I. K., Santoni Rugiu, Eric, Ravn, J., Hansen, A., Christensen, I. J., Jensen, T., Jensen, P. B., Askaa, J., Knudsen, S. & Sørensen, Jens Benn, 2016, In: Journal of Clinical Oncology. e20007.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2015
- Published
High RRM1 Expression Is Associated with Adverse Outcome in Patients with Cisplatin/Vinorelbine-treated Malignant Pleural Mesothelioma
Zimling, Z. G., Santoni Rugiu, Eric, Bech, C. & Sørensen, Jens Benn, Dec 2015, In: Anticancer Research. 35, 12, p. 6731-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methylation-associated Silencing of microRNA-126 and its Host Gene EGFL7 in Malignant Pleural Mesothelioma
Andersen, M., Trapani, D., Ravn, J., Sørensen, Jens Benn, Andersen, C. B., Grauslund, M. & Santoni Rugiu, Eric, Nov 2015, In: Anticancer Research. 35, 11, p. 6223-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term Oncologic and Financial Implications of Lung Cancer Screening
Pedersen, J. J. H. & Sørensen, Jens Benn, May 2015, In: Thoracic Surgery Clinics. 25, 2, p. 223-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prevalence of EGFR mutations in non-small cell lung cancer in an unselected Caucasian population
Skov, B. G., Høgdall, E., Clementsen, P., Krasnik, M., Larsen, Klaus Richter, Sørensen, Jens Benn, Skov, T. & Mellemgaard, A., Feb 2015, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 123, 2, p. 108-115 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methylation-associated Silencing of microRNA-126 and its Host Gene EGFL7 in Malignant Pleural Mesothelioma
Andersen, Morten, Trapani, D., Ravn, J., Sørensen, Jens Benn, Andersen, C. B., Grauslund, M. & Santoni Rugiu, Eric, 2015, In: Anticancer Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of TUBB3 for patient stratification and prognosis in lung cancer
Jakobsen, J. N., Santoni Rugiu, Eric & Sørensen, Jens Benn, 2015, In: Lung Cancer Management.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of next Generation Sequencing to Distinguish Origin of Poorly Differentiated Carcinomas in the Lung from Carcinomas in Other Organs
Sørensen, Jens Benn, Grauslund, M., Melchior, L., Urbanska, E. & Santoni Rugiu, Eric, 2015, In: Journal of Thoracic Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Versatile multigene expression biomarker for predicting clinical platinum sensitivity in non-small cell lung cancer (NSCLC) and ovarian cancer (OC)
Buhl, I. K., Christensen, I. J., Hansen, A., Jensen, T., Buhl, U. H., Brunner, N., Madsen, M. W., Sørensen, Jens Benn, Ravn, J., Santoni Rugiu, Eric, Askaa, J., Jensen, P. B. & Knudsen, S., 2015, In: Journal of Clinical Oncology. 33, 15, Supplement, e18502.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Diagnostic potential of miR-126, miR-143, miR-145, and miR-652 in malignant pleural mesothelioma
Andersen, M., Grauslund, M., Ravn, J., Sørensen, Jens Benn, Andersen, C. B. & Santoni Rugiu, Eric, Jul 2014, In: The Journal of molecular diagnostics : JMD. 16, 4, p. 418-430 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like Growth Factor Receptor 1 mRNA Expression as a Prognostic Marker in Advanced Non-small Cell Lung Cancer
Vilmar, A., Santoni Rugiu, Eric, Cillas, J. G., Huarriz, M. & Sørensen, Jens Benn, Jun 2014, In: Anticancer Research. 34, 6, p. 2991-2996 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thymidylate synthase protein expression levels remain stable during paclitaxel and carboplatin treatment in non-small cell lung cancer
Jakobsen, J. N., Santoni Rugiu, Eric & Sørensen, Jens Benn, Apr 2014, In: Journal of Cancer Research and Clinical Oncology. 140, 4, p. 645-652 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in RRM1 protein expression between diagnostic biopsies and resection specimens, and changes during carboplatin and paclitaxel treatment, in non-small-cell lung cancer
Jakobsen, J. N., Santoni Rugiu, Eric & Sørensen, Jens Benn, Feb 2014, In: Histopathology. 64, 3, p. 412-420 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in epidermal growth factor receptor expression during chemotherapy in non-small cell lung cancer
Jakobsen, J. N., Santoni Rugiu, Eric & Sørensen, Jens Benn, Jan 2014, In: Cancer Chemotherapy and Pharmacology. 73, 1, p. 131-137 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Longitudinal assessment of TUBB3 expression in non-small cell lung cancer patients
Jakobsen, J. N., Santoni Rugiu, Eric & Sørensen, Jens Benn, Jan 2014, In: Cancer Chemotherapy and Pharmacology. 73, 1, p. 43-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Clinical impact of ki-67 labeling index in non-small cell lung cancer
Jakobsen, J. N. & Sørensen, Jens Benn, 2013, In: Lung Cancer. 79, 1, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concomitant occurrence of EGFR (epidermal growth factor receptor) and KRAS (V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog) mutations in an ALK (anaplastic lymphoma kinase)-positive lung adenocarcinoma patient with acquired resistance to crizotinib: a case report
Rossing, H. H., Grauslund, M., Urbanska, E. M., Melchior, L. C., Rask, C., Costa, J. C., Skov, B. G., Sørensen, Jens Benn & Santoni Rugiu, Eric, 2013, In: BMC Research Notes. 6, December, p. 1-8 8 p., 489.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic potential of microRNAs (miRs) in malignant pleural mesothelioma (MPM)
Andersen, Morten, Grauslund, M., Ravn, J., Sørensen, Jens Benn, Andersen, C. B. & Santoni Rugiu, Eric, 2013, In: Cancer Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
INTRATUMOR VARIATION OF BIOMARKER EXPRESSION BY IMMUNOHISTOCHEMISTRY IN RESECTABLE NON-SMALL CELL LUNG CANCER
Jakobsen, J. N., Santoni Rugiu, Eric & Sørensen, Jens Benn, 2013, In: Journal of Thoracic Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IS RRM1 A PREDICTIVE MARKER FOR VINORELBINE EFFICACY - THE RESULTS FROM A COHORT OF MALIGNANT PLEURAL MESOTHELIOMAS TREATED WITH CISPLATIN AND VINORELBINE
Zimling, Z. G., Santoni Rugiu, Eric, Bech, C. & Sørensen, Jens Benn, 2013, In: Journal of Thoracic Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intratumour variation of biomarker expression by immunohistochemistry in resectable non-small cell lung cancer
Jakobsen, J. N., Santoni Rugiu, Eric, Ravn, J. & Sørensen, Jens Benn, 2013, In: European journal of cancer (Oxford, England : 1990). 49, 11, p. 2494-2503 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PRETREATMENT THYMIDYLATE SYNTHASE PROTEIN EXPRESSION LEVELS REMAINS STABLE DURING PACLITAXEL AND CARBOPLATIN TREATMENT IN NON-SMALL CELL LUNG CANCER
Jakobsen, J. N., Santoni Rugiu, Eric & Sørensen, Jens Benn, 2013, In: Journal of Thoracic Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34406177
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Molecular prediction of adjuvant cisplatin efficacy in Non-Small Cell Lung Cancer (NSCLC)—validation in two independent cohorts
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
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Concomitant driver mutations in advanced EGFR-mutated non-small-cell lung cancer and their impact on erlotinib treatment
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
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Very Early Response Evaluation by PET/MR in Patients with Lung Cancer: Timing and Feasibility
Research output: Contribution to journal › Journal article › Research › peer-review
Published