Kim Theilgaard-Mønch
Clinical Associate Professor, Group leader
Department of Clinical Medicine
Blegdamsvej 9, 2100 København Ø
Theilgaard Group
Ole Maaløes Vej 5
2200 København N.
Member of:
- 2024
- Published
Dose-reduction trials in oncology — aiming for less toxicity and better quality of life at lower costs
Theilgaard-Mønch, Kim & Ehlers, L. H., 2024, In: Nature Reviews Clinical Oncology. 21, p. 81-82Research output: Contribution to journal › Comment/debate › Research
- Submitted
Therapeutic inhibition of DNA-Damage Response and PI3K/AKT signaling in Acute Myleoid Leukemia: A novel therapeutic strategy to boost chemotherapy response and overcome resistance
Theilgaard-Mønch, Kim, 2024, (Submitted) In: J Cell Immunol.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia
Kuusanmäki, H., Dufva, O., Vähä-Koskela, M., Leppä, A-M., Huuhtanen, J., Vänttinen, I. M., Nygren, P. J., Klievink, J., Bouhlal, J. O. V., Pölönen, P., Zhang, Q., Adnan Awad, S., Mancebo-Pérez, C., Saad, J., Miettinen, J. J., Javarappa, K. K., Aakko, S., Ruokoranta, T., Eldfors, S., Heinäniemi, M. & 9 others, , 2023, In: Blood. 141, 13, p. 1610-1625Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes
Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trends in survival and cure after allogeneic haematopoietic cell transplantation for acute myeloid leukaemia from 2000 to 2020: A Danish population-based cohort study
Gjærde, L. K., Jakobsen, L. H., Juhl-Christensen, C., Olesen, G., Petruskevicius, I., Severinsen, M. T., Marcher, C. W., Theilgaard-Mønch, Kim, Andersen, N. S., Friis, L. S., Kornblit, B., Petersen, S. L., Schjødt, I. & Sengeløv, Henrik, 2023, In: British Journal of Haematology. 200, 4, p. e40-e43Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2022
- Published
Effects of chemotherapy dose reductions in overweight patients with acute myeloid leukaemia: A Danish nationwide cohort study
Kristensen, D. T., Nielsen, L. B., Jakobsen, L. H. K., Kristensen, T. C., Jepsen, L. Ø., Schöllkopf, C., Theilgaard-Mønch, Kim, El-Galaly, T. C., Roug, A. S. & Severinsen, M. T., 2022, In: British Journal of Haematology. 199, p. 539-548 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of oxidized nucleotide sanitation by TH1579 and conventional chemotherapy cooperatively enhance oxidative DNA-damage and survival in AML
Centio, A., Estruch Alrich, Montserrat, Reckzeh, K., Sanjiv, K., Vittori, Camilla, Engelhard, Sophia Manon Charlotte, Warpman Berglund, U., Helleday, T. & Theilgaard-Mønch, Kim, 2022, In: Molecular Cancer Therapeutics. p. 703-714Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
Pfeiffer, A., Franciosa, Giulia, Locard-Paulet, Marie, Piga, I., Reckzeh, K., Vemulapalli, V., Blacklow, S. C., Theilgaard-Mønch, Kim, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2022, In: Cancer Research. 82, 11, p. 2141-2155 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Psychotropic Drug Use in Acute Myeloid Leukaemia (AML) and Myelodysplastic Syndrome (MDS): A Danish Nationwide Matched Cohort Study of 2404 AML and 1307 MDS Patients
Jensen, O., Øvlisen, A. K., Jakobsen, L. H., Roug, A. S., Nielsen, R. E., Marcher, C. W., Ebbesen, L. H., Theilgaard-Mønch, Kim, Møller, P., Schöllkopf, C., Torp-Pedersen, Christian, El-Galaly, T. C. & Severinsen, M. T., 2022, In: Clinical Epidemiology. 14, p. 225-237 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TET2 deficiency cooperates with CBFB-MYH11 to induce acute myeloid leukaemia and represents an early leukaemogenic event
Reckzeh, K., Estruch Alrich, Montserrat, Ali, M., Helbo, A. S., Mosbech, A., Won, K. J., Rücker, F., Döhner, K. & Theilgaard-Mønch, Kim, 2022, In: British Journal of Haematology. 197, 2, p. 201-206Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard
Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia
Sanjiv, K., Calderón-Montaño, J. M., Pham, T. M., Erkers, T., Tsuber, V., Almlöf, I., Höglund, A., Heshmati, Y., Seashore-Ludlow, B., Nagesh Danda, A., Gad, H., Wiita, E., Göktürk, C., Rasti, A., Friedrich, S., Centio, A., Estruch, M., Våtsveen, T. K., Struyf, N., Visnes, T. & 12 others, , 2021, In: Cancer Research. 81, 22, p. 5733-5744 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Combination Treatments for AML
Estruch Alrich, Montserrat, Vittori, Camilla, Muñoz-Montesinos, T., Reckzeh, K. & Theilgaard-Mønch, Kim, 2021, In: Journal of Cellular Immunology. 3, 4, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy
Estruch Alrich, Montserrat, Reckzeh, K., Vittori, Camilla, Centio, A., Ali, M., Engelhard, Sophia Manon Charlotte, Zhao, L., Won, K. J., Liu, P., Porse, Bo Torben & Theilgaard-Mønch, Kim, 2021, In: Leukemia. 35, p. 2030-2042Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting of PI3K/AKT signaling and DNA damage response in acute myeloid leukemia: a novel therapeutic strategy to boost chemotherapy response and overcome resistance
Estruch Alrich, Montserrat, Vittori, Camilla, Montesinos, T. M., Reckzeh, K. & Theilgaard-Mønch, Kim, 2021, In: Cancer Drug Resistance. 4, p. 984-995Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study
Hjort Jakobsen, L., Stidsholt Roug, A., Kiesbye Øvlisen, A., Werenberg Marcher, C., Beier Ommen, H., Theilgaard-Mønch, Kim, Møller, P., Schöllkopf, C., Kristensen, D., Maria Henriette Naur, T., Bøgsted, M., Christoffer El-Galaly, T. & Tang Severinsen, M., 2021, In: British Journal of Haematology. 193, 3, p. 482-487 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The eha research roadmap: normal hematopoiesis
Jaffredo, T., Balduini, A., Bigas, A., Bernardi, R., Bonnet, D., Canque, B., Charbord, P., Cumano, A., Delwel, R., Durand, C., Fibbe, W., Forrester, L., De Franceschi, L., Ghevaert, C., Gjertsen, B., Gottgens, B., Graf, T., Heidenreich, O., Hermine, O., Higgs, D. & 21 others, , 2021, In: HemaSphere. 5, 12, e669.Research output: Contribution to journal › Review › Research › peer-review
- Published
The prognostic impact of anthropometrics in acute myeloid leukemia treated with intensive chemotherapy - A Danish nationwide cohort study
Kristensen, D., Nielsen, L. B., Roug, A. S., Kristensen, T. C., Heath, A., Jacobsen, L. H., Nørgaard, J. M., Jepsen, L. Ø., Schöllkopf, C., Theilgaard-Mønch, Kim & Severinsen, M. T., 2021, In: Leukemia Research. 106, 106567.Research output: Contribution to journal › Comment/debate › Research
- Published
Treatment intensity and survival trends among real-world elderly AML patients diagnosed in the period 2001-2016: a Danish nationwide cohort study
Naur, T. M. H., Jakobsen, L. H., Roug, A. S., El-Galaly, T. C., Marcher, C. W., Nørgaard, J. M., Theilgaard-Mønch, Kim, Møller, Peter, Schöllkopf, C. & Severinsen, M. T., 2021, In: Leukemia and Lymphoma. 62, 8, p. 2014-2017 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- 2020
The prognostic effect of smoking status on intensively treated acute myeloid leukaemia - A Danish nationwide cohort study
Kristensen, D., Nielsen, L. B., Roug, A. S., Kristensen, T. C., El-Galaly, T. C., Nørgaard, J. M., Marcher, C. W., Schöllkopf, C., Theilgaard-Mønch, Kim & Severinsen, M. T., Jul 2020, In: British Journal of Haematology. 190, 2, p. 236-243Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Identification of two distinct pathways of human myelopoiesis
Drissen, R., Thongjuea, S., Theilgaard-Mønch, Kim & Nerlov, C., 2019, In: Science immunology. 4, 35, eaau7148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML
Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin
Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Gut microbiota sustains hematopoiesis
Theilgaard-Mønch, Kim, 9 Feb 2017, In: Blood. 129, 6, p. 662-663 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2016
- Published
Low-molecular-weight carbohydrate Pentaisomaltose may replace dimethyl sulfoxide as a safer cryoprotectant for cryopreservation of peripheral blood stem cells
Svalgaard, J. D., Haastrup, E. K., Reckzeh, K., Holst, B., Glovinski, P. V., Gørløv, J. S., Hansen, Morten Bagge, Theilgaard-Mønch, Kim, Clausen, C. & Fischer-Nielsen, A., May 2016, In: Transfusion. 56, 5, p. 1088-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Cellular origin of prognostic chromosomal aberrations in AML patients
Mora-Jensen, H., Jendholm, L. J., Rapin, N. P. J., Andersen, M. K., Roug, A. S., Bagger, F. O., Bullinger, L., Winther, Ole, Borregaard, N., Porse, Bo Torben & Theilgaard-Mønch, Kim, 11 Feb 2015, In: Leukemia. 29, p. 1785-1789 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation
Knudsen, K. J., Rehn, M. C., Hasemann, M. S., Rapin, N. P. J., Bagger, F. O., Ohlsson, E. K., Willer, A., Frank, Anne-Katrine, Søndergaard, E., Jendholm, L. J., Thorén, L. A. M., Lee, J., Rak, J., Theilgaard-Mønch, Kim & Porse, Bo Torben, 2015, In: Genes & Development. 29, p. 1915-1929 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
New potential agents for cryopreservation of hematopoietic and adipose stromal cells
Svalgaard, J., Haastrup, E., Brink, A., Clausen, C., Holst, Birgitte, Theilgaard-Mønch, Kim, Reckzeh, K. & Fischer-Nielsen, A., Apr 2014, In: Cytotherapy. 16, Supplement 4, p. S58Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients
Rapin, N. P. J., Bagger, F. O., Jendholm, L. J., Mora-Jensen, H., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 6 Feb 2014, In: Blood (online). 123, 6, p. 894-904 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential expression of granulopoiesis related genes in neutrophil subsets distinguished by membrane expression of CD177
Hu, N., Mora-Jensen, H., Theilgaard-Mønch, Kim, Doornbos-van der Meer, B., Huitema, M. G., Stegeman, C. A., Heeringa, P., Kallenberg, C. G. M. & Westra, J., 2014, In: PLOS ONE. 9, 6, p. e99671 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Thorén, L. A. M., Jendholm, L. J., Winther, Ole & Porse, Bo Torben, 2013, In: Nucleic Acids Research. 41, Database issue, p. D1034-D1039 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving The Analysis Of Gene Expression Profiles By Comparing AML Blasts With Their Nearest Normal Counterparts
Rapin, N., Bagger, F. O., Jendholm, J., Mora-Jensen, H. I., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 2013, In: Blood. 122, 21Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
MicroRNA profiling in human neutrophils during bone marrow granulopoiesis and in vivo exudation
Larsen, M. T., Hother, C., Häger, M., Pedersen, C. C., Theilgaard-Mønch, Kim, Borregaard, N. & Cowland, J. B., 2013, In: P L o S One. 8, 3, 13 p., e58454.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis
Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Jendholm, L. J., Winther, O. & Porse, Bo Torben, 2012, In: Blood. 119, 26, p. 6394-6395 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Phosphorylation of Serine 248 of C/EBPa Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency
Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Theilgaard-Mønch, Kim, Pedersen, T. Å., Nerlov, C. & Porse, Bo Torben, 2012, In: P L o S One. 7, 6, p. e38841Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Immunophenotypical characterization of human neutrophil differentiation
Jensen, H. M., Jendholm, J., Fossum, A., Porse, Bo Torben, Borregaad, N. & Theilgaard-Mønch, Kim, 7 Jun 2011, In: Journal of Leukocyte Biology. p. 629-634 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hematopoietic Stem Cell Biology, Series Stem Cell Biology and Regenerative Medicine, Humana Press, New York, USA, 1st Edn 2010. ISBN 978-160327-346-6: Book Review
Theilgaard-Mønch, Kim, Jan 2011, In: European Journal of Haematology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression profiling in MDS and AML: potential and future avenues
Theilgaard-Mönch, K., Boultwood, J., Ferrari, S., Giannopoulos, K., Hernandez-Rivas, J. M., Kohlmann, A., Morgan, M., Porse, B., Tagliafico, E., Zwaan, C. M., Wainscoat, J., Van den Heuvel-Eibrink, M. M., Mills, K., Bullinger, L., Theilgaard-Mönch, K., Boultwood, J., Ferrari, S., Giannopoulos, K., Hernandez-Rivas, J. M., Kohlmann, A. & 8 others, , 2011, In: Leukemia. 25, 6, p. 909-20 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia
Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Hematopoietic Stem Cell Protocols
Theilgaard-Mønch, Kim, 2008, In: European Journal of Haematology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO).
Kirkeby, Agnete, Torup, L., Bochsen, L., Kjalke, M., Abel, K., Theilgaard-Mønch, Kim, Johansson, P. I., Bjørn, S. E., Gerwien, J. & Leist, M., 2008, In: Thrombosis and Haemostasis. 99, 4, p. 720-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Kirstetter, P., Schuster, Mikkel Bruhn, Bereshchenko, O., Moore, S., Dvinge, H., Kurz, E., Theilgaard-Mønch, Kim, Månsson, R., Pedersen, T. A., Pabst, T., Schrock, E., Porse, Bo Torben, Jacobsen, S. E. W., Bertone, P., Tenen, D. G. & Nerlov, C., 2008, In: Cancer Cell. 13, 4, p. 299-310 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.
Hasemann, M. S., Damgaard, I., Schuster, Mikkel Bruhn, Theilgaard-Mønch, Kim, Sørensen, A. B., Mrsic, A., Krugers, T., Ylstra, B., Pedersen, F. S., Nerlov, C. & Porse, Bo Torben, 2008, In: Blood. 111, 8, p. 4309-21 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.
Weischenfeldt, Joachim Lütken, Damgaard, I., Bryder, D., Theilgaard-Mønch, Kim, Thoren, L. A., Nielsen, F. C., Jacobsen, S. E. W., Nerlov, C. & Porse, Bo Torben, 2008, In: Genes & Development. 22, 10, p. 1381-96 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.
Jacobsen, L. C., Sørensen, O. E., Cowland, J. B., Borregaard, N. & Theilgaard-Mønch, Kim, 2008, In: Journal of Leukocyte Biology. 83, 5, p. 1155-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
Jacobsen, L. C., Theilgaard-Mønch, Kim, Christensen, E. I. & Borregaard, N., 2007, In: Blood. 109, 7, p. 3084-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Neutrophil granules: a library of innate immunity proteins.
Borregaard, N., Sørensen, O. E. & Theilgaard-Mønch, Kim, 2007, In: Trends in Immunology. 28, 8, p. 340-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Bracken, A. P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Mønch, Kim, Minucci, S., Porse, Bo Torben, Marine, J., Hansen, K. H. & Helin, K., 2007, In: Genes & Development. 21, 5, p. 525-30 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes.
Nilsson, L., Edén, P., Olsson, E., Månsson, R., Astrand-Grundström, I., Strömbeck, B., Theilgaard-Mønch, Kim, Anderson, K., Hast, R., Hellström-Lindberg, E., Samuelsson, J., Bergh, G., Nerlov, C., Johansson, B., Sigvardsson, M., Borg, A. & Jacobsen, S. E. W., 2007, In: Blood. 110, 8, p. 3005-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.
Theilgaard-Mønch, Kim, Jacobsen, L. C., Nielsen, M. J., Rasmussen, T., Udby, L., Gharib, M., Arkwright, P. D., Gombart, A. F., Calafat, J., Moestrup, S. K., Porse, Bo Torben & Borregaard, N., 2006, In: Blood. 108, 1, p. 353-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Intractable diarrhoea of infancy caused by neutrophil specific granule deficiency and cured by stem cell transplantation.
Wynn, R. F., Sood, M., Theilgaard-Mønch, Kim, Jones, C. J., Gombart, A. F., Gharib, M., Koeffler, H. P., Borregaard, N. & Arkwright, P. D., 2006, In: Gut. 55, 2, p. 292-3 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils.
Theilgaard-Mønch, Kim, Jacobsen, L. C., Rasmussen, T., Niemann, C. U., Udby, L., Borup, R., Gharib, M., Arkwright, P. D., Gombart, A. F., Calafat, J., Porse, Bo Torben & Borregaard, N., 2005, In: Journal of Leukocyte Biology. 78, 2, p. 462-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of ID-1 as a potential target gene of MMSET in multiple myeloma.
Hudlebusch, H., Theilgaard-Mønch, Kim, Lodahl, M., Johnsen, H. & Rasmussen, T., 2005, In: British Journal of Haematology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage.
Porse, Bo Torben, Bryder, D., Theilgaard-Mønch, Kim, Hasemann, M. S., Anderson, K., Damgaard, I., Jacobsen, S. E. W. & Nerlov, C., 2005, In: Journal of Experimental Medicine. 202, 1, p. 85-96 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems biology of neutrophil differentiation and immune response.
Theilgaard-Mønch, Kim, Porse, Bo Torben & Borregaard, N., 2005, In: Current Opinion in Immunology. 18, 1, p. 54-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
Neutrophils and keratinocytes in innate immunity--cooperative actions to provide antimicrobial defense at the right time and place.
Borregaard, N., Theilgaard-Mønch, Kim, Cowland, J. B., Ståhle, M. & Sørensen, O. E., 2004, In: Journal of Leukocyte Biology. 77, 4, p. 439-43 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
The transcriptional activation program of human neutrophils in skin lesions supports their important role in wound healing.
Theilgaard-Mønch, Kim, Knudsen, S., Follin, P. & Borregaard, N., 2004, In: Journal of Immunology. 172, 12, p. 7684-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The transcriptional program of terminal granulocytic differentiation.
Theilgaard-Mønch, Kim, Jacobsen, L. C., Borup, R., Rasmussen, T., Bjerregaard, M. D., Nielsen, F. C., Cowland, J. B. & Borregaard, N., 2004, In: Blood. 105, 4, p. 1785-96 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
Occurrence of dysregulated oncogenes in primary plasma cells representing consecutive stages of myeloma pathogenesis: indications for different disease entities.
Rasmussen, T., Theilgaard-Mønch, Kim, Hudlebusch, H. R., Lodahl, M., Johnsen, H. E. & Dahl, I. M. S., 2003, In: British Journal of Haematology. 123, 2, p. 253-62 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Pluripotent and myeloid-committed CD34+ subsets in hematopoietic stem cell allografts.
Theilgaard-Mønch, Kim, Raaschou-Jensen, K., Schjødt, K., Heilmann, C., Vindeløv, L., Jacobsen, N. & Dickmeiss, E., 2003, In: Bone Marrow Transplantation. 32, 12, p. 1125-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors.
Sørensen, O. E., Cowland, J. B., Theilgaard-Mønch, Kim, Liu, L., Ganz, T. & Borregaard, N., 2003, In: Journal of Immunology. 170, 11, p. 5583-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool.
Sitnicka, E., Bryder, D., Theilgaard-Mønch, Kim, Buza-Vidas, N., Adolfsson, J. & Jacobsen, S. E. W., 2002, In: Immunity. 17, 4, p. 463-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
Flow cytometric assessment of lymphocyte subsets, lymphoid progenitors, and hematopoietic stem cells in allogeneic stem cell grafts.
Theilgaard-Mønch, Kim, Raaschou-Jensen, K., Palm, H., Schjødt, K., Heilmann, C., Vindeløv, L., Jacobsen, N. & Dickmeiss, E., 2001, In: Bone Marrow Transplantation. 28, 11, p. 1073-82 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Profiling of gene expression in individual hematopoietic cells by global mRNA amplification and slot blot analysis.
Theilgaard-Mønch, Kim, Cowland, J. & Borregaard, N., 2001, In: Journal of Immunological Methods. 252, 1-2, p. 175-89 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Regulation of human neutrophil granule protein expression.
Borregaard, N., Theilgaard-Mønch, Kim, Sørensen, O. E. & Cowland, J. B., 2001, In: Current Opinion in Hematology. 8, 1, p. 23-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation.
Bryder, D., Ramsfjell, V., Dybedal, I., Theilgaard-Mønch, Kim, Högerkorp, C. M., Adolfsson, J., Borge, O. J. & Jacobsen, S. E., 2001, In: Journal of Experimental Medicine. 194, 7, p. 941-52 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity.
Adolfsson, J., Borge, O. J., Bryder, D., Theilgaard-Mønch, Kim, Astrand-Grundström, I., Sitnicka, E., Sasaki, Y. & Jacobsen, S. E., 2001, In: Immunity. 15, 4, p. 659-69 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
A comparative study of CD34+ cells, CD34+ subsets, colony forming cells and cobblestone area forming cells in cord blood and bone marrow allografts.
Theilgaard-Mønch, Kim, Raaschou-Jensen, K., Heilmann, C., Andersen, H., Bock, J., Russel, C. A., Vindeløv, L., Jacobsen, N. & Dickmeiss, E., 1999, In: European Journal of Haematology. 62, 3, p. 174-83 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Single leukapheresis products collected from healthy donors after the administration of granulocyte colony-stimulating factor contain ten-fold higher numbers of long-term reconstituting hematopoietic progenitor cells than conventional bone marrow allografts.
Theilgaard-Mønch, Kim, Raaschou-Jensen, K., Andersen, H., Russell, C. A., Vindeløv, L., Jacobsen, N. & Dickmeiss, E., 1999, In: Bone Marrow Transplantation. 23, 3, p. 243-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3997971
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HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
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Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML
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Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
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