Kristian Karstoft

Kristian Karstoft

Clinical Associate Professor

Member of:

  • Clinical Pharmacology


Publication year:
  1. 2024
  2. Published

    The Body weight Reducing Effects of Tirzepatide in People with and without Type 2 Diabetes: A Review on Efficacy and Adverse Effects

    Jensen, T. L., Brønden, Andreas, Karstoft, Kristian, Sonne, David Peick & Christensen, Mikkel Bring, 2024, In: Patient Preference and Adherence. 18, p. 373-382 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. 2023
  4. Published

    Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial

    Legaard, G. E., Lyngbæk, M. P. P., Almdal, T. P., Karstoft, K., Bennetsen, S. L., Feineis, C. S., Nielsen, N. S., Durrer, C. G., Liebetrau, B., Nystrup, U., Østergaard, M., Thomsen, K., Trinh, B., Solomon, T. P. J., Van Hall, G., Brønd, J. C., Holst, J. J., Hartmann, B., Christensen, R., Pedersen, B. K. & 1 others, Ried-Larsen, M., 2023, In: Nature Metabolism. 5, p. 880–895

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Effects of different doses of exercise in adjunct to diet-induced weight loss on the AGE-RAGE axis in patients with short standing type 2 diabetes: Secondary analysis of the DOSE-EX multi-arm, parallel-group, randomised trial

    Legaard, G. E., Lyngbaek, M. P. P., Almdal, Thomas Peter, Durrer, C. G., Nystrup, U., Larsen, E. L., Poulsen, Henrik Enghusen, Karstoft, Kristian, Pedersen, Bente Klarlund & Ried-Larsen, M., 2023, In: Free Radical Biology and Medicine. 208, p. 52-61 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Predicting the HbA1c level following glucose-lowering interventions in individuals with HbA1c-defined prediabetes: a post-hoc analysis from the randomized controlled PRE-D trial

    Bruhn, L., Vistisen, D., Amadid, H., Clemmensen, K. K. B., Karstoft, Kristian, Ried-Larsen, M., Persson, F., Jørgensen, M. E., Møller, C. L., Stallknecht, Bente Merete, Færch, K. & Blond, Martin Bæk, 2023, In: Endocrine. 81, p. 67–76

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Protocol for DEprescribing and Care to reduce Antipsychotics in Dementia (DECADE)-A hybrid effectiveness-implementation pilot study

    Benthien, K. S., Lech, L. V. J., Birke, H., Jørgensen, S. M., Andersen, T., Hansen, S. V., Andersen, Jon Thor Trærup, Karstoft, Kristian, Schiøtz, M. & Vermehren, Charlotte, 2023, In: PLoS ONE. 18, 11 , 12 p., e0294024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes

    Maurer, J., Zhao, X., Irmler, M., Gudiksen, Anders, Pilmark, N. S., Li, Q., Goj, T., Beckers, J., Hrabě De Angelis, M., Birkenfeld, A. L., Peter, A., Lehmann, R., Pilegaard, Henriette, Karstoft, Kristian, Xu, G. & Weigert, C., 2023, In: American Journal of Physiology: Cell Physiology. 325, 4, p. C1131-C1143 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The effect of metformin treatment on volumes of free-living physical activity and sedentary behaviour: A post-hoc analysis of the PRE-D trial

    Karstoft, Kristian, Ried-larsen, M., Bruhn, L., Pilmark, N. S., Hansen, K. B., Persson, F., Jørgensen, M. E., Blond, Martin Bæk & Færch, K., 2023, In: Journal of Sports Sciences. 41, 18, p. 1687-1691 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Tirzepatide. Dual GLP-1/GIP receptor agonist, Treatment of type 2 diabetes and obesity

    Jensen, T. L., Brønden, Andreas, Karstoft, Kristian, Sonne, David Peick & Christensen, Mikkel Bring, 2023, In: Drugs of the Future. 48, 3, p. 179-196 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Withdrawn accelerated approvals for cancer indications in the USA: what is the marketing authorisation status in the EU?

    Cramer, A., Sørup, F. K. H., Christensen, H. R., Petersen, Tonny Studsgaard & Karstoft, Kristian, 2023, In: The Lancet. Oncology. 24, 9, p. e385-e394 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. 2022
  13. Published

    Amino Acid Metabolism and Protein Turnover in Lean and Obese Humans During Exercise-Effect of IL-6 Receptor Blockade

    Trinh, B., Peletier, M., Simonsen, C., Plomgaard, Peter Stendahl, Karstoft, Kristian, Pedersen, Bente Klarlund, van Hall, Gerrit & Ellingsgaard, H., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 7, p. 1854-1864

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effects of an exercise-based lifestyle intervention on systemic markers of oxidative stress and advanced glycation endproducts in persons with type 2 diabetes: Secondary analysis of a randomised clinical trial

    Legaard, G. E., Feineis, C. S., Johansen, M. Y., Hansen, K. B., Vaag, Allan, Larsen, E. L., Poulsen, Henrik Enghusen, Almdal, Thomas Peter, Karstoft, Kristian, Pedersen, Bente Klarlund & Ried-Larsen, M., 2022, In: Free Radical Biology and Medicine. 188, p. 328-336 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Exercise and RNA Oxidation

    Larsen, E. L., Karstoft, Kristian & Poulsen, Henrik Enghusen, 2022, Oxidative Eustress in Exercise Physiology. CRC Press, 8 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Impact of intensive lifestyle intervention on gut microbiota composition in type 2 diabetes: a post-hoc analysis of a randomized clinical trial

    Wei, S., Brejnrod, A. D., Trivedi, Urvish, Mortensen, M. S., Johansen, M. Y., Karstoft, Kristian, Vaag, A. A., Ried-Larsen, M. & Sørensen, Søren Johannes, 2022, In: Gut Microbes. 14, 1, 15 p., 2005407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Plasma FGF21 concentrations are regulated by glucose independently of insulin and GLP-1 in lean, healthy humans

    Solomon, T. P. J., Carter, S., Haus, J. M., Karstoft, Kristian, Holstein-Rønsbo, Stephanie, Nielsen, M. S. & Gillum, M. P., 2022, In: PeerJ. 10, 16 p., e12755.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Skeletal muscle adaptations to exercise are not influenced by metformin treatment in humans: secondary analyses of 2 randomised, clinical trials

    Pilmark, N. S., Oberholzer, L., Halling, Jens Frey, Kristensen, Jonas Møller, Bønding, C. P., Elkjær, I., Lyngbæk, M., Elster, G., Siebenmann, C., Holm, N. F., Birk, Jesper Bratz, Larsen, E. L., Meinild-Lundby, A., Wojtaszewski, Jørgen F P, Pilegaard, Henriette, Poulsen, H., Pedersen, Bente Klarlund, Hansen, K. B. & Karstoft, Kristian, 2022, In: Applied Physiology, Nutrition and Metabolism. 47, 3, p. 309-320 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Effects of a Lifestyle Intervention Supported by the InterWalk Smartphone App on Increasing Physical Activity Among Persons With Type 2 Diabetes: Parallel-Group, Randomized Trial

    Thorsen, I. K., Yang, Y., Valentiner, L. S., Glümer, C., Karstoft, Kristian, Brønd, J. C., Nielsen, R. Ø., Brøns, C., Christensen, R., Nielsen, J. S., Vaag, Allan, Pedersen, Bente Klarlund, Langberg, Henning & Ried-Larsen, M., 2022, In: JMIR mHealth and uHealth. 10, 9, 18 p., e30602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

    Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2021
  22. Published

    Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men

    Soberg, S., Löfgren, J., Philipsen, F. E., Jensen, M., Hansen, Adam Espe, Ahrens, E., Nystrup, K. B., Nielsen, R. D., Solling, C., Wedell-Neergaard, A., Berntsen, M., Loft, A., Kjær, Andreas, Gerhart-Hines, Zach, Johannesen, H. H., Pedersen, Bente Klarlund, Karstoft, Kristian & Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Editorial: Understanding the Heterogeneity in Exercise-Induced Changes in Glucose Metabolism to Help Optimize Treatment Outcomes

    Solomon, T. P. J., Thyfault, J. P., Haus, J. M. & Karstoft, Kristian, 2021, In: Frontiers in Endocrinology. 12, 3 p., 699354.

    Research output: Contribution to journalEditorialResearchpeer-review

  24. Published

    Il-6 receptor blockade increases circulating adiponectin levels in people with obesity: An explanatory analysis

    Wueest, S., Seelig, E., Timper, K., Lyngbaek, M. P., Karstoft, Kristian, Donath, M. Y., Ellingsgaard, H. & Konrad, D., 2021, In: Metabolites. 11, 2, 7 p., 79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The effects of dapagliflozin, metformin or exercise on glycaemic variability in overweight or obese individuals with prediabetes (the PRE-D Trial): a multi-arm, randomised, controlled trial

    Færch, K., Blond, M. B., Bruhn, L., Amadid, H., Vistisen, D., Clemmensen, K. K. B., Vainø, C. T. R., Pedersen, C., Tvermosegaard, M., Dejgaard, T. F., Karstoft, Kristian, Ried-Larsen, M., Persson, F. & Jørgensen, M. E., 2021, In: Diabetologia. 64, 1, p. 42-55 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2017
  27. Published

    The effect of alternate-day caloric restriction on the metabolic consequences of 8 days of bed rest in healthy lean men: A randomized trial

    Harder-Lauridsen, N. M., Nielsen, S. T., Porsdam Mann, Sebastian, Lyngbæk, M. P., Benatti, F. B., Langkilde, Annika Reynberg, Law, Ian, Wedell-Neergaard, A. S., Thomsen, C., Møller, Kirsten, Karstoft, Kristian, Pedersen, Bente Klarlund & Krogh-Madsen, Rikke, 1 Feb 2017, In: Journal of Applied Physiology. 122, 2, p. 230-241 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 283313202