Ole Hyldegaard
Clinical Professor
- 2023
- Published
Characterization of patients with odontogenic necrotizing soft tissue infections in the head and neck area: A retrospective analysis
Hansen, S. U., Jespersen, Frederik Viktor Bang, Markvart, Merete, Hyldegaard, Ole, Plaschke, Christina Caroline, Bjarnsholt, Thomas, Nielsen, Claus Henrik & Jensen, Simon Storgård, 2023, In: Acta Odontologica Scandinavica. 82, 1, p. 40-47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of an early intervention with Hyperbaric Oxygen Treatment on arm lymphedema and quality of life after breast cancer-an explorative clinical trial
Ammitzboll, G., Hyldegaard, Ole, Forchhammer, M., Rottensten, H., Lanng, C., Kroman, Niels Thorndahl, Zerahn, B., Jensen, Lars Thorbjørn, Johansen, Christoffer & Dalton, Susanne Oksbjerg, 2023, In: Supportive Care in Cancer. 31, 5, 12 p., 313.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen treatment in the management of necrotising soft-tissue infections: results from a Danish nationwide registry study
Hedetoft, M., Madsen, M. B. & Hyldegaard, Ole, 2023, In: BMJ Open. 13, 2, e066117.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability
Movert, E., Bolarin, J. S., Valfridsson, C., Velarde, J., Skrede, S., Nekludov, M., Hyldegaard, Ole, Arnell, P., Svensson, M., Norrby-Teglund, A., Cho, K. H., Elhaik, E., Wessels, M. R., Råberg, L. & Carlsson, F., 2023, In: Nature Communications. 14, 10 p., 4008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Key pathways and genes that are altered during treatment with hyperbaric oxygen in patients with sepsis due to necrotizing soft tissue infection (HBOmic study)
Vinkel, J., Rib, Leonor, Buil, A., Hedetoft, M. & Hyldegaard, Ole, 2023, In: European Journal of Medical Research. 28, 1, 14 p., 507.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutrophil-derived reactive agents induce a transient SpeB negative phenotype in Streptococcus pyogenes
INFECT Study Group, I. S. G., 2023, In: Journal of Biomedical Science. 30, 1, 16 p., 52.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systemic immune activation profiles in streptococcal necrotizing soft tissue infections: A prospective multicenter study
INFECT Study Group, I. S. G., 2023, In: Clinical Immunology. 249, 11 p., 109276.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Mechanisms of Action of Hyperbaric Oxygen in Restoring Host Homeostasis during Sepsis
Vinkel, J., Arenkiel, B. & Hyldegaard, Ole, 2023, In: Biomolecules. 13, 8, 19 p., 1228.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
Hyperbaric oxygen treatment of mandibular osteoradionecrosis: Combined data from the two randomized clinical trials DAHANCA-21 and NWHHT2009-1
Forner, L. E., Dieleman, F. J., Shaw, R. J., Kanatas, A., Butterworth, C. J., Kjeller, G., Alsner, J., Overgaard, J., Hillerup, S., Hyldegaard, Ole, Arnell, P., von Buchwald, Christian, Kaanders, J. H. A. M., Smeele, L. E., Specht, Lena, Johansen, J., Witjes, M. J. H., Merkx, M. A. W. & Jansen, E. C., Jan 2022, In: Radiotherapy and Oncology. 166, p. 137-144 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections
Jahagirdar, S., Morris, L., Benis, N., Oppegaard, O., Svenson, M., Hyldegaard, Ole, Skrede, S., Norrby-Teglund, A., INFECT Study Group, I. S. G., Martins dos Santos, V. A. P. & Saccenti, E., 2022, In: BMC Medicine. 20, 173.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Decision support system and outcome prediction in a cohort of patients with necrotizing soft-tissue infections
Katz, S., Suijker, J., Hardt, C., Madsen, M. B., Vries, A. M. D., Pijpe, A., Skrede, S., Hyldegaard, Ole, Solligård, E., Norrby-Teglund, A., Saccenti, E. & Martins dos Santos, V. A. P., 2022, In: International Journal of Medical Informatics. 167, 9 p., 104878.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections
Jensen, Peter Østrup, Møller, S. A., Stjernekilde, S., Olsen, P., Moser, Claus Ernst, Schwartz, F. A., Lerche, C. J., Høiby, Niels, Hyldegaard, Ole, Faurholt-jepsen, D. & Kolpen, Mette, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 201-223 (Antibiofilm Strategies, Vol. 11).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Increase in the Complement Activation Product C4d and the Terminal Complement Complex sC5b-9 Is Associated with Disease Severity and a Fatal Outcome in Necrotizing Soft-Tissue Infection
Hedetoft, M., Madsen, M. B., Hansen, C. B., Hyldegaard, Ole & Garred, Peter, 2022, In: Journal of Innate Immunity. 14, 4, p. 355-365 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the Effects of Hyperbaric Oxygen Treatment in Necrotizing Soft Tissue Infection With Transcriptomics and Machine Learning (the HBOmic Study): Protocol for a Prospective Cohort Study With Data Validation
Vinkel, J., Rib, Leonor, Buil, A., Hedetoft, M. & Hyldegaard, Ole, 2022, In: JMIR Research Protocols. 11, 11, e39252.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis
Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.Research output: Contribution to journal › Review › Research › peer-review
- 2021
- Published
Risk Factors and Predictors of Mortality in Streptococcal Necrotizing Soft-tissue Infections: A Multicenter Prospective Study
INFECT Study Group, I. S. G., 27 Jan 2021, In: Clinical Infectious Diseases. 72, 2, p. 293-300 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-invasive monitoring of carboxyhemoglobin during hyperbaric oxygen therapy
Bidstrup, D., Ravn, F., Smidt-Nielsen, I. G., Wahl, A. M., Jansen, E. C. & Hyldegaard, Ole, 1 Jan 2021, In: Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. 48, 1, p. 33-42 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between YKL-40 and markers of disease severity and death in patients with necrotizing soft-tissue infection
Hedetoft, M., Hansen, M. B., Madsen, M. B., Johansen, Julia Sidenius & Hyldegaard, Ole, 2021, In: BMC Infectious Diseases. 21, 1046.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discriminatory plasma biomarkers predict specific clinical phenotypes of necrotizing soft-tissue infections
Palma Medina, L. M., Rath, E., Jahagirdar, S., Bruun, T., Madsen, M. B., Strålin, K., Unge, C., Hansen, M. B., Arnell, P., Nekludov, M., Hyldegaard, Ole, Lourda, M., Martins dos Santos, V. A. P., Saccenti, E., Skrede, S., Svensson, M. & Norrby-Teglund, A., 2021, In: Journal of Clinical Investigation. 131, 14, e149523.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of immunoglobulin G on cytokine response in necrotising soft-tissue infection: A post hoc analysis
Hedetoft, M., Madsen, M. B., Perner, Anders, Garred, Peter & Hyldegaard, Ole, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 9, p. 1293-1299 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection
Hedetoft, M., Jensen, Peter Østrup, Moser, Claus Ernst, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Investigative Medicine. 69, 7, p. 1330-1338Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection
Hedetoft, M., Moser, Claus Ernst, Jensen, Peter Østrup, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Applied Physiology. 130, 3, p. 729-736 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Effects of adding adjunctive hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers: a protocol for a systematic review with meta-analysis and trial sequential analysis
Vinkel, J., Holm, N. F. R., Jakobsen, J. C. & Hyldegaard, Ole, 29 Jun 2020, In: BMJ Open. 10, 6, 14 p., e031708.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Periocular necrotizing soft tissue infection in Greater Copenhagen
Würtz, N. S., Mikkelsen, L. H., Jørgensen, J. S., Hansen, M. S., Madsen, M. B., Hyldegaard, Ole & Heegaard, Steffen, Mar 2020, In: Acta Ophthalmologica. 98, 2, p. 207-212Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complement Activation Is Associated With Mortality in Patients With Necrotizing Soft-Tissue Infections—A Prospective Observational Study
Kristensen, M. K., Hansen, M. B., Madsen, M. B., Hansen, Cecilie Bo, Pilely, K., Hyldegaard, Ole & Garred, Peter, 2020, In: Frontiers in Immunology. 11, 17.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 47983795
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Treatment with 24 h-delayed normo- and hyperbaric oxygenation in severe sepsis induced by cecal ligation and puncture in rats
Research output: Contribution to journal › Journal article › Research › peer-review
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122
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Molecular profiling of tissue biopsies reveals unique signatures associated with streptococcal necrotizing soft tissue infections
Research output: Contribution to journal › Journal article › Research › peer-review
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119
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Protein SIC secreted from Streptococcus pyogenes forms complexes with extracellular histones that boost cytokine production
Research output: Contribution to journal › Journal article › Research › peer-review
Published