Ole Hyldegaard

Ole Hyldegaard

Clinical Professor

Member of:

  • Anaesthesiology


Publication year:
All
1 - 50 out of 77Page size: 50
  1. 2023
  2. Published

    Characterization of patients with odontogenic necrotizing soft tissue infections in the head and neck area: A retrospective analysis

    Hansen, S. U., Jespersen, Frederik Viktor Bang, Markvart, Merete, Hyldegaard, Ole, Plaschke, Christina Caroline, Bjarnsholt, Thomas, Nielsen, Claus Henrik & Jensen, Simon Storgård, 2023, In: Acta Odontologica Scandinavica. 82, 1, p. 40-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Effects of an early intervention with Hyperbaric Oxygen Treatment on arm lymphedema and quality of life after breast cancer-an explorative clinical trial

    Ammitzboll, G., Hyldegaard, Ole, Forchhammer, M., Rottensten, H., Lanng, C., Kroman, Niels Thorndahl, Zerahn, B., Jensen, Lars Thorbjørn, Johansen, Christoffer & Dalton, Susanne Oksbjerg, 2023, In: Supportive Care in Cancer. 31, 5, 12 p., 313.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Hyperbaric oxygen treatment in the management of necrotising soft-tissue infections: results from a Danish nationwide registry study

    Hedetoft, M., Madsen, M. B. & Hyldegaard, Ole, 2023, In: BMJ Open. 13, 2, e066117.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability

    Movert, E., Bolarin, J. S., Valfridsson, C., Velarde, J., Skrede, S., Nekludov, M., Hyldegaard, Ole, Arnell, P., Svensson, M., Norrby-Teglund, A., Cho, K. H., Elhaik, E., Wessels, M. R., Råberg, L. & Carlsson, F., 2023, In: Nature Communications. 14, 10 p., 4008.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Key pathways and genes that are altered during treatment with hyperbaric oxygen in patients with sepsis due to necrotizing soft tissue infection (HBOmic study)

    Vinkel, J., Rib, Leonor, Buil, A., Hedetoft, M. & Hyldegaard, Ole, 2023, In: European Journal of Medical Research. 28, 1, 14 p., 507.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Neutrophil-derived reactive agents induce a transient SpeB negative phenotype in Streptococcus pyogenes

    INFECT Study Group, I. S. G., 2023, In: Journal of Biomedical Science. 30, 1, 16 p., 52.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Systemic immune activation profiles in streptococcal necrotizing soft tissue infections: A prospective multicenter study

    INFECT Study Group, I. S. G., 2023, In: Clinical Immunology. 249, 11 p., 109276.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The Mechanisms of Action of Hyperbaric Oxygen in Restoring Host Homeostasis during Sepsis

    Vinkel, J., Arenkiel, B. & Hyldegaard, Ole, 2023, In: Biomolecules. 13, 8, 19 p., 1228.

    Research output: Contribution to journal › Review › Research › peer-review

  10. 2022
  11. Published

    Hyperbaric oxygen treatment of mandibular osteoradionecrosis: Combined data from the two randomized clinical trials DAHANCA-21 and NWHHT2009-1

    Forner, L. E., Dieleman, F. J., Shaw, R. J., Kanatas, A., Butterworth, C. J., Kjeller, G., Alsner, J., Overgaard, J., Hillerup, S., Hyldegaard, Ole, Arnell, P., von Buchwald, Christian, Kaanders, J. H. A. M., Smeele, L. E., Specht, Lena, Johansen, J., Witjes, M. J. H., Merkx, M. A. W. & Jansen, E. C., Jan 2022, In: Radiotherapy and Oncology. 166, p. 137-144 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections

    Jahagirdar, S., Morris, L., Benis, N., Oppegaard, O., Svenson, M., Hyldegaard, Ole, Skrede, S., Norrby-Teglund, A., INFECT Study Group, I. S. G., Martins dos Santos, V. A. P. & Saccenti, E., 2022, In: BMC Medicine. 20, 173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Decision support system and outcome prediction in a cohort of patients with necrotizing soft-tissue infections

    Katz, S., Suijker, J., Hardt, C., Madsen, M. B., Vries, A. M. D., Pijpe, A., Skrede, S., Hyldegaard, Ole, Solligård, E., Norrby-Teglund, A., Saccenti, E. & Martins dos Santos, V. A. P., 2022, In: International Journal of Medical Informatics. 167, 9 p., 104878.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Hyperbaric Oxygen Treatment May Advance the Outcome of Antibiotic Treatment of Biofilm Infections

    Jensen, Peter Østrup, Møller, S. A., Stjernekilde, S., Olsen, P., Moser, Claus Ernst, Schwartz, F. A., Lerche, C. J., Høiby, Niels, Hyldegaard, Ole, Faurholt-jepsen, D. & Kolpen, Mette, 2022, Antibiofilm Strategies: Current and Future Applications to Prevent, Control and Eradicate Biofilms. Springer, p. 201-223 (Antibiofilm Strategies, Vol. 11).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    Increase in the Complement Activation Product C4d and the Terminal Complement Complex sC5b-9 Is Associated with Disease Severity and a Fatal Outcome in Necrotizing Soft-Tissue Infection

    Hedetoft, M., Madsen, M. B., Hansen, C. B., Hyldegaard, Ole & Garred, Peter, 2022, In: Journal of Innate Immunity. 14, 4, p. 355-365 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Investigating the Effects of Hyperbaric Oxygen Treatment in Necrotizing Soft Tissue Infection With Transcriptomics and Machine Learning (the HBOmic Study): Protocol for a Prospective Cohort Study With Data Validation

    Vinkel, J., Rib, Leonor, Buil, A., Hedetoft, M. & Hyldegaard, Ole, 2022, In: JMIR Research Protocols. 11, 11, e39252.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Potential Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis

    Lerche, C. J., Schwartz, F., Pries-Heje, M. M., Fosbøl, E. L., Iversen, Kasper, Jensen, Peter Østrup, Høiby, Niels, Hyldegaard, Ole, Bundgård, Henning & Moser, Claus Ernst, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 805964.

    Research output: Contribution to journal › Review › Research › peer-review

  18. 2021
  19. Published

    Risk Factors and Predictors of Mortality in Streptococcal Necrotizing Soft-tissue Infections: A Multicenter Prospective Study

    INFECT Study Group, I. S. G., 27 Jan 2021, In: Clinical Infectious Diseases. 72, 2, p. 293-300 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Non-invasive monitoring of carboxyhemoglobin during hyperbaric oxygen therapy

    Bidstrup, D., Ravn, F., Smidt-Nielsen, I. G., Wahl, A. M., Jansen, E. C. & Hyldegaard, Ole, 1 Jan 2021, In: Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. 48, 1, p. 33-42 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Associations between YKL-40 and markers of disease severity and death in patients with necrotizing soft-tissue infection

    Hedetoft, M., Hansen, M. B., Madsen, M. B., Johansen, Julia Sidenius & Hyldegaard, Ole, 2021, In: BMC Infectious Diseases. 21, 1046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Discriminatory plasma biomarkers predict specific clinical phenotypes of necrotizing soft-tissue infections

    Palma Medina, L. M., Rath, E., Jahagirdar, S., Bruun, T., Madsen, M. B., Strålin, K., Unge, C., Hansen, M. B., Arnell, P., Nekludov, M., Hyldegaard, Ole, Lourda, M., Martins dos Santos, V. A. P., Saccenti, E., Skrede, S., Svensson, M. & Norrby-Teglund, A., 2021, In: Journal of Clinical Investigation. 131, 14, e149523.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Effect of immunoglobulin G on cytokine response in necrotising soft-tissue infection: A post hoc analysis

    Hedetoft, M., Madsen, M. B., Perner, Anders, Garred, Peter & Hyldegaard, Ole, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 9, p. 1293-1299 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection

    Hedetoft, M., Jensen, Peter Østrup, Moser, Claus Ernst, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Investigative Medicine. 69, 7, p. 1330-1338

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection

    Hedetoft, M., Moser, Claus Ernst, Jensen, Peter Østrup, Vinkel, J. & Hyldegaard, Ole, 2021, In: Journal of Applied Physiology. 130, 3, p. 729-736 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2020
  27. Published

    Effects of adding adjunctive hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers: a protocol for a systematic review with meta-analysis and trial sequential analysis

    Vinkel, J., Holm, N. F. R., Jakobsen, J. C. & Hyldegaard, Ole, 29 Jun 2020, In: BMJ Open. 10, 6, 14 p., e031708.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Periocular necrotizing soft tissue infection in Greater Copenhagen

    Würtz, N. S., Mikkelsen, L. H., Jørgensen, J. S., Hansen, M. S., Madsen, M. B., Hyldegaard, Ole & Heegaard, Steffen, Mar 2020, In: Acta Ophthalmologica. 98, 2, p. 207-212

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Complement Activation Is Associated With Mortality in Patients With Necrotizing Soft-Tissue Infections—A Prospective Observational Study

    Kristensen, M. K., Hansen, M. B., Madsen, M. B., Hansen, Cecilie Bo, Pilely, K., Hyldegaard, Ole & Garred, Peter, 2020, In: Frontiers in Immunology. 11, 17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections

    Bergsten, H., Madsen, M. B., Bergey, F., Hyldegaard, Ole, Skrede, S., Arnell, P., Oppegaard, O., Itzek, A., Perner, Anders, Svensson, M., Norrby-Teglund, A. & INFECT Study Group, I. S. G., 2020, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 71, 7, p. 1772-1775 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Effect of progressive resistance training on persistent pain after axillary dissection in breast cancer: a randomized controlled trial

    Ammitzbøll, G., Andersen, K. G., Bidstrup, Pernille Envold Hansen, Johansen, Christoffer, Lanng, C., Kroman, Niels Thorndahl, Zerahn, B., Hyldegaard, Ole, Andersen, E. W. & Dalton, Susanne Oksbjerg, 2020, In: Breast Cancer Research and Treatment. 179, p. 173–183

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Incidence, comorbidity and mortality in patients with necrotising soft-tissue infections, 2005-2018: A Danish nationwide register-based cohort study

    Hedetoft, M., Madsen, M. B., Madsen, L. B. & Hyldegaard, Ole, 2020, In: BMJ Open. 10, 10, 8 p., e041302.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Integrated Univariate, Multivariate, and Correlation-Based Network Analyses Reveal Metabolite-Specific Effects on Bacterial Growth and Biofilm Formation in Necrotizing Soft Tissue Infections

    Afzal, M., Saccenti, E., Madsen, M. B., Hansen, M. B., Hyldegaard, Ole, Skrede, S., Martins Dos Santos, V. A. P., Norrby-Teglund, A. & Svensson, M., 2020, In: Journal of Proteome Research. 19, 2, p. 688-698

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Measurement of peripheral arterial tonometry in patients with diabetic foot ulcers during courses of hyperbaric oxygen treatment

    Hedetoft, M., Olsen, N. V., Smidt-Nielsen, I. G., Wahl, A. M., Bergström, A., Juul, Anders & Hyldegaard, Ole, 2020, In: Diving and Hyperbaric Medicine. 50, 1, p. 17-23

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Necrotizing Soft-Tissue Infections: Clinical Features and Diagnostic Aspects

    Madsen, M. B., Arnell, P. & Hyldegaard, Ole, 2020, Advances in Experimental Medicine and Biology. Schweiz: Springer VS, Vol. 1294. p. 39-52 (Advances in Experimental Medicine and Biology, Vol. 1294).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  36. Published

    Oxygen under tryk som behandling

    Hyldegaard, Ole & Hedetoft, M., 2020, In: Ugeskrift for Laeger. 182, 44, 6 p., V06200463.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. 2019
  38. Published

    Radiation-induced cystitis treated with hyperbaric oxygen therapy (RICH-ART): a randomised, controlled, phase 2–3 trial

    Oscarsson, N., Müller, B., Rosén, A., Lodding, P., Mölne, J., Giglio, D., Hjelle, K. M., Vaagbø, G., Hyldegaard, Ole, Vangedal, M., Salling, L., Kjellberg, A., Lind, F., Ettala, O., Arola, O. & Seeman-Lodding, H., Nov 2019, In: The Lancet Oncology. 20, 11, p. 1602-1614

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Molecular profiling of tissue biopsies reveals unique signatures associated with streptococcal necrotizing soft tissue infections

    Thänert, R., Itzek, A., Hoßmann, J., Hamisch, D., Madsen, M. B., Hyldegaard, Ole, Skrede, S., Bruun, T., Norrby-Teglund, A., INFECT Study Group, I. S. G., Medina, E. & Pieper, D. H., Aug 2019, In: Nature Communications. 10, 15 p., 3846.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Effect of progressive resistance training on health-related quality of life in the first year after breast cancer surgery - results from a randomized controlled trial

    Ammitzbøll, G., Kristina Kjær, T., Johansen, Christoffer, Lanng, C., Wreford Andersen, E., Kroman, Niels Thorndahl, Zerahn, B., Hyldegaard, Ole, Envold Bidstrup, P. & Dalton, Susanne Oksbjerg, May 2019, In: Acta Oncologica. 58, 5, p. 665-672 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: A replicated, randomized controlled clinical trial

    Wahl, A. M., Bidstrup, D., Smidt-Nielsen, I. G., Werner, M. U., Hyldegaard, Ole & Rotbøll-Nielsen, P., 2019, In: Journal of Pain Research. 12, p. 2337-2348

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Group A Streptococcal DNase Sda1 Impairs Plasmacytoid Dendritic Cells' Type 1 Interferon Response

    Keller, N., Woytschak, J., Heeb, L. E. M., Marques Maggio, E., Mairpady Shambat, S., Snäll, J., Hyldegaard, Ole, Boyman, O., Norrby-Teglund, A. & Zinkernagel, A. S., 2019, In: The Journal of Investigative Dermatology. 139, 6, p. 1284-1293

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Lægelig godkendelse af personer med diabetes til rekreativ dykning

    Helledie, G., Vinkel, J., Christiansen, E. & Hyldegaard, Ole, 2019, In: Ugeskrift for Laeger. 181, 3, 5 p., V12170903.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    New editor of Diving and Hyperbaric Medicine

    Hyldegaard, Ole, 2019, In: Diving and Hyperbaric Medicine. 49, 1, 1 p., 68.

    Research output: Contribution to journal › Editorial › Research

  45. Published

    Only minor stem cell mobilization in head and neck irradiated patients treated with hyperbaric oxygen

    Forner, L., Berkowicz, A., Dickmeiss, E., Hyldegaard, Ole, Jansen, E. C. & Fischer-Nielsen, A., 2019, In: Diving and Hyperbaric Medicine. 49, 3, p. 175-185

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Patient’s characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study

    Madsen, M. B., Skrede, S., Perner, Anders, Arnell, P., Nekludov, M., Bruun, T., Karlsson, Y., Hansen, M. B., Polzik, P., Hedetoft, M., Rosén, A., Saccenti, E., Bergey, F., Martins dos Santos, V. A. P., INFECT Study Group, I. S. G., Norrby-Teglund, A. & Hyldegaard, Ole, 2019, In: Intensive Care Medicine. 45, p. 1241-1251 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Progressive resistance training to prevent arm lymphedema in the first year after breast cancer surgery: Results of a randomized controlled trial

    Ammitzbøll, G., Johansen, Christoffer, Lanng, C., Andersen, E. W., Kroman, Niels Thorndahl, Zerahn, B., Hyldegaard, Ole, Wittenkamp, M. C. & Dalton, Susanne Oksbjerg, 2019, In: Cancer. 125, 10, p. 1683-1692 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    SuPAR correlates with mortality and clinical severity in patients with necrotizing soft-tissue infections: results from a prospective, observational cohort study

    Polzik, P., Grøndal, O., Tavenier, J., Madsen, M. B., Andersen, Ove, Hedetoft, M. & Hyldegaard, Ole, 2019, In: Scientific Reports. 9, 8 p., 5098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The clinical use of hyperbaric oxygen in the treatment of Danish patients with diabetic foot ulcers

    Vinkel, J., Lohse, N. & Hyldegaard, Ole, 2019, In: Danish Medical Journal. 66, 2, 6 p., A5528.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2018
  51. Published

    Associations of Plasma Nitrite, L-Arginine and Asymmetric Dimethylarginine With Morbidity and Mortality in Patients With Necrotizing Soft Tissue Infections

    Hansen, M. B., Rasmussen, L. S., Garred, Peter, Pilely, K., Wahl, A. M., Perner, Anders, Madsen, M. B., Hedegaard, E. R., Simonsen, U. & Hyldegaard, Ole, 2018, In: Shock. 49, 6, p. 667-674

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Diabetes and necrotizing soft tissue infections - A prospective observational cohort study: Statistical analysis plan

    Rosén, A., Arnell, P., Madsen, M. B., Nedrebø, B. G., Norrby-Teglund, A., Hyldegaard, Ole, Dos Santos, V. M., Bergey, F., Saccenti, E., INFECT Study Group, I. S. G. & Skrede, S., 2018, In: Acta Anaesthesiologica Scandinavica. 62, 8, p. 1171-1177

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Forensic Case Reports Presenting Immersion Pulmonary Edema as a Differential Diagnosis in Fatal Diving Accidents

    Vinkel, J., Bak, P., Juel Thiis Knudsen, P. & Hyldegaard, Ole, 2018, In: Journal of Forensic Sciences. 63, 1, p. 299-304 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Immunoregulation of Neutrophil Extracellular Trap Formation by Endothelial-Derived p33 (gC1q Receptor)

    Neumann, A., Papareddy, P., Westman, J., Hyldegaard, Ole, Snäll, J., Norrby-Teglund, A. & Herwald, H., 2018, In: Journal of Innate Immunity. 10, 1, p. 30-43

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Necrotizing soft tissue infections - a multicentre, prospective observational study (INFECT): protocol and statistical analysis plan

    Madsen, M. B., Skrede, S., Bruun, T., Arnell, P., Rosén, A., Nekludov, M., Karlsson, Y., Bergey, F., Saccenti, E., Martins dos Santos, V. A. P., Perner, Anders, Norrby-Teglund, A. & Hyldegaard, Ole, 2018, In: Acta Anaesthesiologica Scandinavica. 62, 2, p. 272-279

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Neuronal nitric oxide inhibition attenuates the protective effect of HBO2 during cyanide poisoning

    Hedetoft, M., Polzik, P., Olsen, N. V. & Hyldegaard, Ole, 2018, In: Undersea & Hyperbaric Medicine. 45, 3, p. 335-350

    Research output: Contribution to journal › Journal article › Research › peer-review

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