A definition and clinical grading of Modic changes

Research output: Contribution to journal › Review › Research › peer-review

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A definition and clinical grading of Modic changes. / Udby, Peter M.; Samartzis, Dino; Carreon, Leah Y.; Andersen, Mikkel Østerheden; Karppinen, Jaro; Modic, Michael.

In: Journal of Orthopaedic Research, Vol. 40, No. 2, 2022, p. 301-307.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Udby, PM, Samartzis, D, Carreon, LY, Andersen, MØ, Karppinen, J & Modic, M 2022, 'A definition and clinical grading of Modic changes', Journal of Orthopaedic Research, vol. 40, no. 2, pp. 301-307. https://doi.org/10.1002/jor.25240

APA

Udby, P. M., Samartzis, D., Carreon, L. Y., Andersen, M. Ø., Karppinen, J., & Modic, M. (2022). A definition and clinical grading of Modic changes. Journal of Orthopaedic Research, 40(2), 301-307. https://doi.org/10.1002/jor.25240

Vancouver

Udby PM, Samartzis D, Carreon LY, Andersen MØ, Karppinen J, Modic M. A definition and clinical grading of Modic changes. Journal of Orthopaedic Research. 2022;40(2):301-307. https://doi.org/10.1002/jor.25240

Author

Udby, Peter M. ; Samartzis, Dino ; Carreon, Leah Y. ; Andersen, Mikkel Østerheden ; Karppinen, Jaro ; Modic, Michael. / A definition and clinical grading of Modic changes. In: Journal of Orthopaedic Research. 2022 ; Vol. 40, No. 2. pp. 301-307.

Bibtex

@article{9fe4b59d6fa4443d844687488db5efff,

title = "A definition and clinical grading of Modic changes",

abstract = "To provide an up-to-date description of knowledge and pitfalls related to the classification, definition and grading of Modic changes (MC) visualized on magnetic resonance imaging (MRI). State-of-the-art review of current knowledge regarding the definition and grading of MC on MRI. MC on MRI have been reported to be associated with low back pain and disability. However, previous studies have shown heterogeneous results in regards to the impact of MC and its clinical relevance in patients with back pain. MC is a term used with considerable variation in the literature. No strict definition has been provided previously, this has contributed to varying diagnostic inclusion criteria, heterogeneous study populations, and discrepancy in results. A definition of MC and a proposal for grading is provided in this state-of-the-art review. MC are important, clinically relevant findings. However, issues with the nomenclature, definition and grading of these changes need to be addressed. Our current review highlights relevant issues related to MC, and provides a definition and grading score for the term MC that includes the Modic type and the extent of vertebral body involvement. Future studies should seek to validate the MC grading score in clinically relevant populations.",

author = "Udby, {Peter M.} and Dino Samartzis and Carreon, {Leah Y.} and Andersen, {Mikkel {\O}sterheden} and Jaro Karppinen and Michael Modic",

note = "Publisher Copyright: {\textcopyright} 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC",

year = "2022",

doi = "10.1002/jor.25240",

language = "English",

volume = "40",

pages = "301--307",

journal = "Journal of Orthopaedic Research",

issn = "0736-0266",

publisher = "JohnWiley & Sons, Inc.",

number = "2",

}

RIS

TY - JOUR

T1 - A definition and clinical grading of Modic changes

AU - Udby, Peter M.

AU - Samartzis, Dino

AU - Carreon, Leah Y.

AU - Andersen, Mikkel Østerheden

AU - Karppinen, Jaro

AU - Modic, Michael

PY - 2022

Y1 - 2022

N2 - To provide an up-to-date description of knowledge and pitfalls related to the classification, definition and grading of Modic changes (MC) visualized on magnetic resonance imaging (MRI). State-of-the-art review of current knowledge regarding the definition and grading of MC on MRI. MC on MRI have been reported to be associated with low back pain and disability. However, previous studies have shown heterogeneous results in regards to the impact of MC and its clinical relevance in patients with back pain. MC is a term used with considerable variation in the literature. No strict definition has been provided previously, this has contributed to varying diagnostic inclusion criteria, heterogeneous study populations, and discrepancy in results. A definition of MC and a proposal for grading is provided in this state-of-the-art review. MC are important, clinically relevant findings. However, issues with the nomenclature, definition and grading of these changes need to be addressed. Our current review highlights relevant issues related to MC, and provides a definition and grading score for the term MC that includes the Modic type and the extent of vertebral body involvement. Future studies should seek to validate the MC grading score in clinically relevant populations.

AB - To provide an up-to-date description of knowledge and pitfalls related to the classification, definition and grading of Modic changes (MC) visualized on magnetic resonance imaging (MRI). State-of-the-art review of current knowledge regarding the definition and grading of MC on MRI. MC on MRI have been reported to be associated with low back pain and disability. However, previous studies have shown heterogeneous results in regards to the impact of MC and its clinical relevance in patients with back pain. MC is a term used with considerable variation in the literature. No strict definition has been provided previously, this has contributed to varying diagnostic inclusion criteria, heterogeneous study populations, and discrepancy in results. A definition of MC and a proposal for grading is provided in this state-of-the-art review. MC are important, clinically relevant findings. However, issues with the nomenclature, definition and grading of these changes need to be addressed. Our current review highlights relevant issues related to MC, and provides a definition and grading score for the term MC that includes the Modic type and the extent of vertebral body involvement. Future studies should seek to validate the MC grading score in clinically relevant populations.

U2 - 10.1002/jor.25240

DO - 10.1002/jor.25240

M3 - Review

C2 - 34910328

AN - SCOPUS:85121687145

VL - 40

SP - 301

EP - 307

JO - Journal of Orthopaedic Research

JF - Journal of Orthopaedic Research

SN - 0736-0266

IS - 2

ER -

ID: 321651150