Acute posterior multifocal placoid pigment epitheliopathy resembling multiple sclerosis
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Acute posterior multifocal placoid pigment epitheliopathy resembling multiple sclerosis. / El Mahdaoui, Sahla; Isenberg, Asher Lou; Hansen, Klaus; Langkilde, Annika Reynberg; Hamann, Steffen; Romme Christensen, Jeppe.
In: Practical Neurology, Vol. 22, No. 6, 2022, p. 515-517.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Acute posterior multifocal placoid pigment epitheliopathy resembling multiple sclerosis
AU - El Mahdaoui, Sahla
AU - Isenberg, Asher Lou
AU - Hansen, Klaus
AU - Langkilde, Annika Reynberg
AU - Hamann, Steffen
AU - Romme Christensen, Jeppe
N1 - Publisher Copyright: © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2022
Y1 - 2022
N2 - A 23-year-old man presented with right eye blurred vision; he was diagnosed with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), and his symptoms resolved with prednisolone. Two months later, he developed a right arm weakness that resolved after 3 weeks. MR scan of brain identified changes suggesting multiple sclerosis, with four hyperintense FLAIR lesions; there was contrast enhancement of two lesions and no diffusion restriction. Cerebrospinal fluid showed mononuclear pleocytosis. We eventually diagnosed these as APMPPE-associated CNS lesions. APMPPE is a rare inflammatory chorioretinopathy that rarely can resemble multiple sclerosis clinically and radiologically.
AB - A 23-year-old man presented with right eye blurred vision; he was diagnosed with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), and his symptoms resolved with prednisolone. Two months later, he developed a right arm weakness that resolved after 3 weeks. MR scan of brain identified changes suggesting multiple sclerosis, with four hyperintense FLAIR lesions; there was contrast enhancement of two lesions and no diffusion restriction. Cerebrospinal fluid showed mononuclear pleocytosis. We eventually diagnosed these as APMPPE-associated CNS lesions. APMPPE is a rare inflammatory chorioretinopathy that rarely can resemble multiple sclerosis clinically and radiologically.
KW - MRI
KW - multiple sclerosis
KW - ophthalmology
KW - stroke
KW - vasculitis
U2 - 10.1136/pn-2022-003463
DO - 10.1136/pn-2022-003463
M3 - Journal article
C2 - 35863880
AN - SCOPUS:85135185388
VL - 22
SP - 515
EP - 517
JO - Practical Neurology
JF - Practical Neurology
SN - 1474-7758
IS - 6
ER -
ID: 327139549