Circulating Biomarkers Involved in the Development of and Progression to Chronic Pancreatitis — A Literature Review
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Circulating Biomarkers Involved in the Development of and Progression to Chronic Pancreatitis — A Literature Review. / Poulsen, Valborg Vang; Hadi, Amer; Werge, Mikkel Parsberg; Karstensen, John Gásdal; Novovic, Srdan.
In: Biomolecules, Vol. 14, No. 2, 239, 2024.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Circulating Biomarkers Involved in the Development of and Progression to Chronic Pancreatitis — A Literature Review
AU - Poulsen, Valborg Vang
AU - Hadi, Amer
AU - Werge, Mikkel Parsberg
AU - Karstensen, John Gásdal
AU - Novovic, Srdan
N1 - Publisher Copyright: © 2024 by the authors.
PY - 2024
Y1 - 2024
N2 - Chronic pancreatitis (CP) is the end-stage of continuous inflammation and fibrosis in the pancreas evolving from acute- to recurrent acute-, early, and, finally, end-stage CP. Currently, prevention is the only way to reduce disease burden. In this setting, early detection is of great importance. Due to the anatomy and risks associated with direct sampling from pancreatic tissue, most of our information on the human pancreas arises from circulating biomarkers thought to be involved in pancreatic pathophysiology or injury. The present review provides the status of circulating biomarkers involved in the development of and progression to CP.
AB - Chronic pancreatitis (CP) is the end-stage of continuous inflammation and fibrosis in the pancreas evolving from acute- to recurrent acute-, early, and, finally, end-stage CP. Currently, prevention is the only way to reduce disease burden. In this setting, early detection is of great importance. Due to the anatomy and risks associated with direct sampling from pancreatic tissue, most of our information on the human pancreas arises from circulating biomarkers thought to be involved in pancreatic pathophysiology or injury. The present review provides the status of circulating biomarkers involved in the development of and progression to CP.
KW - acute pancreatitis
KW - chronic pancreatitis
KW - fibrosis
KW - inflammation
KW - oxidative stress
U2 - 10.3390/biom14020239
DO - 10.3390/biom14020239
M3 - Review
C2 - 38397476
AN - SCOPUS:85185899307
VL - 14
JO - Biomolecules
JF - Biomolecules
SN - 2218-273X
IS - 2
M1 - 239
ER -
ID: 384477028