Free-living energy expenditure reduced after deep brain stimulation surgery for Parkinson's disease
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Free-living energy expenditure reduced after deep brain stimulation surgery for Parkinson's disease. / Jørgensen, Hans Ulrik; Werdelin, Lene; Lokkegaard, Annemette; Westerterp, Klaas R; Simonsen, Lene.
In: Clinical Physiology and Functional Imaging, Vol. 32, No. 3, 2012, p. 214-20.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Free-living energy expenditure reduced after deep brain stimulation surgery for Parkinson's disease
AU - Jørgensen, Hans Ulrik
AU - Werdelin, Lene
AU - Lokkegaard, Annemette
AU - Westerterp, Klaas R
AU - Simonsen, Lene
N1 - © 2011 The Authors. Clinical Physiology and Functional Imaging © 2011 Scandinavian Society of Clinical Physiology and Nuclear Medicine.
PY - 2012
Y1 - 2012
N2 - The clinical picture in Parkinson's disease (PD) is characterized by bradykinesia, rigidity, resting tremor and postural instability. In advanced stages of the disease, many patients will experience reduced efficacy of medication with fluctuations in symptoms and dyskinesias. Surgical treatment with deep brain stimulation in the subthalamic nucleus (STN-DBS) is now considered the gold standard in fluctuating PD. Many patients experience a gain of weight following the surgery. The aim of this study was to identify possible mechanisms, which may contribute to body weight gain in patients with PD following bilateral STN-DBS surgery.
AB - The clinical picture in Parkinson's disease (PD) is characterized by bradykinesia, rigidity, resting tremor and postural instability. In advanced stages of the disease, many patients will experience reduced efficacy of medication with fluctuations in symptoms and dyskinesias. Surgical treatment with deep brain stimulation in the subthalamic nucleus (STN-DBS) is now considered the gold standard in fluctuating PD. Many patients experience a gain of weight following the surgery. The aim of this study was to identify possible mechanisms, which may contribute to body weight gain in patients with PD following bilateral STN-DBS surgery.
U2 - 10.1111/j.1475-097X.2011.01079.x
DO - 10.1111/j.1475-097X.2011.01079.x
M3 - Journal article
VL - 32
SP - 214
EP - 220
JO - Clinical Physiology and Functional Imaging
JF - Clinical Physiology and Functional Imaging
SN - 1475-0961
IS - 3
ER -
ID: 48518754