Incidence and associated risk factors of venous thromboembolism after open and laparoscopic partial nephrectomy in patients administered short-period thromboprophylaxis: a Danish nationwide population-based cohort study
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Incidence and associated risk factors of venous thromboembolism after open and laparoscopic partial nephrectomy in patients administered short-period thromboprophylaxis : a Danish nationwide population-based cohort study. / Azawi, Nessn H.; Tolouee, Sara; Dabestani, Saeed.
In: Scandinavian Journal of Urology, Vol. 57, No. 1-6, 2023, p. 81-85.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Incidence and associated risk factors of venous thromboembolism after open and laparoscopic partial nephrectomy in patients administered short-period thromboprophylaxis
T2 - a Danish nationwide population-based cohort study
AU - Azawi, Nessn H.
AU - Tolouee, Sara
AU - Dabestani, Saeed
N1 - Publisher Copyright: © 2023 Acta Chirurgica Scandinavica Society.
PY - 2023
Y1 - 2023
N2 - Objective: To report the risk of venous thromboembolism (VTE) after partial nephrectomy in Denmark. Materials and methods: A nationwide population-based registry was used to conduct a retrospective cohort study. All partial nephrectomies from January 2010 to August 2018 were assessed for postoperative VTE events. Univariable and multivariable analyses were used to evaluate the odds of postoperative VTE within 4 weeks and 4 months after partial nephrectomy in patients who received standard-of-care thromboprophylaxis. Results: Among 2355 patients, postoperative VTE risk was 0.6% and 0.9%, at 4 weeks and 4 months, respectively. In multivariate analysis, prior VTE (OR = 24.9, p < 0.001) and length of hospital stay (OR = 0.89, p < 0.001) were predictors of postoperative VTE within 4 months after partial nephrectomy. Limitations included the retrospective and registry-based study design and the absence of BMI data. Conclusion: Incidence of postoperative VTE is rare, but patients with prior VTE and those with a greater length of hospital stay are at greater long-term risk and should be evaluated when considering thromboprophylaxis.
AB - Objective: To report the risk of venous thromboembolism (VTE) after partial nephrectomy in Denmark. Materials and methods: A nationwide population-based registry was used to conduct a retrospective cohort study. All partial nephrectomies from January 2010 to August 2018 were assessed for postoperative VTE events. Univariable and multivariable analyses were used to evaluate the odds of postoperative VTE within 4 weeks and 4 months after partial nephrectomy in patients who received standard-of-care thromboprophylaxis. Results: Among 2355 patients, postoperative VTE risk was 0.6% and 0.9%, at 4 weeks and 4 months, respectively. In multivariate analysis, prior VTE (OR = 24.9, p < 0.001) and length of hospital stay (OR = 0.89, p < 0.001) were predictors of postoperative VTE within 4 months after partial nephrectomy. Limitations included the retrospective and registry-based study design and the absence of BMI data. Conclusion: Incidence of postoperative VTE is rare, but patients with prior VTE and those with a greater length of hospital stay are at greater long-term risk and should be evaluated when considering thromboprophylaxis.
KW - Partial nephrectomy
KW - predictive model
KW - thromboembolism risk factors
KW - thromboprophylaxis
KW - venous thromboembolism
U2 - 10.1080/21681805.2023.2171112
DO - 10.1080/21681805.2023.2171112
M3 - Journal article
C2 - 36703546
AN - SCOPUS:85147445608
VL - 57
SP - 81
EP - 85
JO - Scandinavian Journal of Urology
JF - Scandinavian Journal of Urology
SN - 2168-1805
IS - 1-6
ER -
ID: 370661447