I this case report a 37-year-old nulliparous woman was admitted for acute onset of abdominal pain. CT scan showed a homogeneous tumour related to the internal genitalia and extravasation of contrast material, but the site of bleeding was not identifiable. Ultrasonography revealed leiomyoma and haemoperitoneum, and emergency laparoscopy was performed. There was an ongoing venous bleeding from two subserosal myomas. Myomectomy was done, and 588 g tissue was removed with a benign histology. Spontaneous rupture of a vessel overlying a uterine myoma has been documented in the literature, though it is extremely rare.