Peripheral T-cell activation, Th17 cells, regulatory T-cells, and aortic aneurysm in people with HIV
Research output: Contribution to journal › Letter › Research › peer-review
Here, we investigate if peripheral T-cell activation and proportion of Th17 and T-regulatory cells (Tregs) are associated with aortic aneurysm or aortic diameter in people with HIV. Aorta was examined by computed tomography scans and T-cells by flow cytometry in 428 participants, and aortic aneurysm was found in 32 participants. None of the T-cell subsets were associated with aortic aneurysm, but activated T-cells and Tregs had opposite association to aorta diameter indicating an inverse impact.
Original language | English |
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Journal | AIDS |
Volume | 37 |
Issue number | 11 |
Pages (from-to) | 1765-1767 |
Number of pages | 3 |
ISSN | 0269-9370 |
DOIs | |
Publication status | Published - 2023 |
Bibliographical note
Funding Information:
The study was funded by an unrestricted research grant from Novo Nordisk Foundation and by a grant from Rigshospitalets Research Council. The funders had no role in design or in conducting the study.
Publisher Copyright:
© 2023 Lippincott Williams and Wilkins. All rights reserved.
ID: 369359984