Shortened duration of untreated first episode of psychosis: changes in patient characteristics at treatment

Research output: Contribution to journalJournal articleResearchpeer-review

  • Tor Ketil Larsen
  • T H McGlashan
  • Jan Olav Johannessen
  • Svein Friis
  • C Guldberg
  • U Haahr
  • M Horneland
  • I Melle
  • L C Moe
  • S Opjordsmoen
  • Simonsen, Erik
  • P Vaglum

OBJECTIVE: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment.

METHOD: Two study groups were ascertained in the same Norwegian health care sector: one from 1993-1994 with usual detection methods and one from 1997-1998 with early detection strategies that included education about psychosis.

RESULTS: Patients with early detection had a shorter median duration of untreated psychosis by 21.5 weeks than patients with usual detection. The number with psychosis was greater in the early detection group; the number with schizophrenia was less. Early detection patients had more substance abuse and were younger, better adjusted premorbidly, and less ill.

CONCLUSIONS: Early detection can shorten duration of untreated psychosis and help more patients when they are less severely ill. Given the devastation of psychosis, this is a significant treatment advance.

Original languageEnglish
JournalThe American Journal of Psychiatry
Volume158
Issue number11
Pages (from-to)1917-9
Number of pages3
ISSN0002-953X
DOIs
Publication statusPublished - Nov 2001

    Research areas

  • Adult, Antipsychotic Agents, Female, Humans, Male, Schizophrenia, Schizophrenic Psychology, Severity of Illness Index, Social Adjustment, Time Factors, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.

ID: 186481182