ß(3) adrenergic stimulation of the cardiac Na+-K+ pump by reversal of an inhibitory oxidative modification
Research output: Contribution to journal › Journal article › Research › peer-review
inhibition of L-type Ca(2+) current contributes to negative inotropy of ß(3) adrenergic receptor (ß(3) AR) activation, but effects on other determinants of excitation-contraction coupling are not known. Of these, the Na(+)-K(+) pump is of particular interest because of adverse effects attributed to high cardiac myocyte Na(+) levels and upregulation of the ß(3) AR in heart failure.
Original language | English |
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Journal | Circulation |
Volume | 122 |
Issue number | 25 |
Pages (from-to) | 2699-708 |
Number of pages | 10 |
DOIs | |
Publication status | Published - 2010 |
ID: 34164275