An overview of the synergy and crosstalk between pentraxins and collectins/ficolins: their functional relevance in complement activation

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An overview of the synergy and crosstalk between pentraxins and collectins/ficolins : their functional relevance in complement activation. / Ma, Ying Jie; Lee, Bok Luel; Garred, Peter.

In: Experimental & Molecular Medicine, Vol. 49, e320, 21.04.2017.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Ma, YJ, Lee, BL & Garred, P 2017, 'An overview of the synergy and crosstalk between pentraxins and collectins/ficolins: their functional relevance in complement activation', Experimental & Molecular Medicine, vol. 49, e320. https://doi.org/10.1038/emm.2017.51

APA

Ma, Y. J., Lee, B. L., & Garred, P. (2017). An overview of the synergy and crosstalk between pentraxins and collectins/ficolins: their functional relevance in complement activation. Experimental & Molecular Medicine, 49, [e320]. https://doi.org/10.1038/emm.2017.51

Vancouver

Ma YJ, Lee BL, Garred P. An overview of the synergy and crosstalk between pentraxins and collectins/ficolins: their functional relevance in complement activation. Experimental & Molecular Medicine. 2017 Apr 21;49. e320. https://doi.org/10.1038/emm.2017.51

Author

Ma, Ying Jie ; Lee, Bok Luel ; Garred, Peter. / An overview of the synergy and crosstalk between pentraxins and collectins/ficolins : their functional relevance in complement activation. In: Experimental & Molecular Medicine. 2017 ; Vol. 49.

Bibtex

@article{8f0909b4cdbb4be3bc98076219825458,
title = "An overview of the synergy and crosstalk between pentraxins and collectins/ficolins: their functional relevance in complement activation",
abstract = "The complement system is an innate immune defense machinery comprising components that deploy rapid immune responses and provide efficient protection against foreign invaders and unwanted host elements. The complement system is activated upon recognition of pathogenic microorganisms or altered self-cells by exclusive pattern recognition molecules (PRMs), such as collectins, ficolins and pentraxins. Recent accumulating evidence shows that the different classes of effector PRMs build up a co-operative network and exert synergistic effects on complement activation. In this review, we describe our updated view of the crosstalk between previously unlinked PRMs in complement activation and the potential pathogenic effects during infection and inflammation.",
keywords = "Journal Article, Review",
author = "Ma, {Ying Jie} and Lee, {Bok Luel} and Peter Garred",
year = "2017",
month = apr,
day = "21",
doi = "10.1038/emm.2017.51",
language = "English",
volume = "49",
journal = "Experimental & Molecular Medicine",
issn = "1226-3613",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - An overview of the synergy and crosstalk between pentraxins and collectins/ficolins

T2 - their functional relevance in complement activation

AU - Ma, Ying Jie

AU - Lee, Bok Luel

AU - Garred, Peter

PY - 2017/4/21

Y1 - 2017/4/21

N2 - The complement system is an innate immune defense machinery comprising components that deploy rapid immune responses and provide efficient protection against foreign invaders and unwanted host elements. The complement system is activated upon recognition of pathogenic microorganisms or altered self-cells by exclusive pattern recognition molecules (PRMs), such as collectins, ficolins and pentraxins. Recent accumulating evidence shows that the different classes of effector PRMs build up a co-operative network and exert synergistic effects on complement activation. In this review, we describe our updated view of the crosstalk between previously unlinked PRMs in complement activation and the potential pathogenic effects during infection and inflammation.

AB - The complement system is an innate immune defense machinery comprising components that deploy rapid immune responses and provide efficient protection against foreign invaders and unwanted host elements. The complement system is activated upon recognition of pathogenic microorganisms or altered self-cells by exclusive pattern recognition molecules (PRMs), such as collectins, ficolins and pentraxins. Recent accumulating evidence shows that the different classes of effector PRMs build up a co-operative network and exert synergistic effects on complement activation. In this review, we describe our updated view of the crosstalk between previously unlinked PRMs in complement activation and the potential pathogenic effects during infection and inflammation.

KW - Journal Article

KW - Review

U2 - 10.1038/emm.2017.51

DO - 10.1038/emm.2017.51

M3 - Review

C2 - 28428631

VL - 49

JO - Experimental & Molecular Medicine

JF - Experimental & Molecular Medicine

SN - 1226-3613

M1 - e320

ER -

ID: 186450352