Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children

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Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children. / Tiendrebeogo, Regis W; Adu, Bright; Singh, Susheel K; Dziegiel, Morten H; Nébié, Issa; Sirima, Sodiomon B; Christiansen, Michael; Dodoo, Daniel; Theisen, Michael.

In: Open forum in Infectious Diseases, Vol. 2, No. 2, ofv044, 2015.

Research output: Contribution to journalLetterResearchpeer-review

Harvard

Tiendrebeogo, RW, Adu, B, Singh, SK, Dziegiel, MH, Nébié, I, Sirima, SB, Christiansen, M, Dodoo, D & Theisen, M 2015, 'Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children', Open forum in Infectious Diseases, vol. 2, no. 2, ofv044. https://doi.org/10.1093/ofid/ofv044

APA

Tiendrebeogo, R. W., Adu, B., Singh, S. K., Dziegiel, M. H., Nébié, I., Sirima, S. B., Christiansen, M., Dodoo, D., & Theisen, M. (2015). Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children. Open forum in Infectious Diseases, 2(2), [ofv044]. https://doi.org/10.1093/ofid/ofv044

Vancouver

Tiendrebeogo RW, Adu B, Singh SK, Dziegiel MH, Nébié I, Sirima SB et al. Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children. Open forum in Infectious Diseases. 2015;2(2). ofv044. https://doi.org/10.1093/ofid/ofv044

Author

Tiendrebeogo, Regis W ; Adu, Bright ; Singh, Susheel K ; Dziegiel, Morten H ; Nébié, Issa ; Sirima, Sodiomon B ; Christiansen, Michael ; Dodoo, Daniel ; Theisen, Michael. / Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children. In: Open forum in Infectious Diseases. 2015 ; Vol. 2, No. 2.

Bibtex

@article{44eb47ba0626420bb0c321316a59bc36,
title = "Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children",
abstract = "The antibody-dependent respiratory burst and opsonic phagocytosis assays have been associated with protection against malaria; however, other mechanisms may also be involved. The antibody-dependent cellular inhibition (ADCI) assay is yet to be correlated with protection in longitudinal cohort studies (LCS). We investigated the relationship between ADCI activity of immunoglobulin G before malaria season and risk of malaria in a LCS involving Ghanaian children. High ADCI activity was significantly associated with reduced risk against malaria. Findings here suggest a potential usefulness of the ADCI assay as a correlate of protection to guide malaria vaccine studies.",
author = "Tiendrebeogo, {Regis W} and Bright Adu and Singh, {Susheel K} and Dziegiel, {Morten H} and Issa N{\'e}bi{\'e} and Sirima, {Sodiomon B} and Michael Christiansen and Daniel Dodoo and Michael Theisen",
year = "2015",
doi = "10.1093/ofid/ofv044",
language = "English",
volume = "2",
journal = "Open Forum Infectious Diseases",
issn = "2328-8957",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Antibody-dependent cellular inhibition is associated with reduced risk against febrile malaria in a longitudinal cohort study involving Ghanaian children

AU - Tiendrebeogo, Regis W

AU - Adu, Bright

AU - Singh, Susheel K

AU - Dziegiel, Morten H

AU - Nébié, Issa

AU - Sirima, Sodiomon B

AU - Christiansen, Michael

AU - Dodoo, Daniel

AU - Theisen, Michael

PY - 2015

Y1 - 2015

N2 - The antibody-dependent respiratory burst and opsonic phagocytosis assays have been associated with protection against malaria; however, other mechanisms may also be involved. The antibody-dependent cellular inhibition (ADCI) assay is yet to be correlated with protection in longitudinal cohort studies (LCS). We investigated the relationship between ADCI activity of immunoglobulin G before malaria season and risk of malaria in a LCS involving Ghanaian children. High ADCI activity was significantly associated with reduced risk against malaria. Findings here suggest a potential usefulness of the ADCI assay as a correlate of protection to guide malaria vaccine studies.

AB - The antibody-dependent respiratory burst and opsonic phagocytosis assays have been associated with protection against malaria; however, other mechanisms may also be involved. The antibody-dependent cellular inhibition (ADCI) assay is yet to be correlated with protection in longitudinal cohort studies (LCS). We investigated the relationship between ADCI activity of immunoglobulin G before malaria season and risk of malaria in a LCS involving Ghanaian children. High ADCI activity was significantly associated with reduced risk against malaria. Findings here suggest a potential usefulness of the ADCI assay as a correlate of protection to guide malaria vaccine studies.

U2 - 10.1093/ofid/ofv044

DO - 10.1093/ofid/ofv044

M3 - Letter

C2 - 26380342

VL - 2

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

SN - 2328-8957

IS - 2

M1 - ofv044

ER -

ID: 144288044