High-affinity human leucocyte antigen class I binding variola-derived peptides induce CD4+ T cell responses more than 30 years post-vaccinia virus vaccination
Research output: Contribution to journal › Journal article › Research › peer-review
Interferon-gamma secreting T lymphocytes against pox virus-derived synthetic 9-mer peptides were tested by enzyme-linked immunospot in peripheral blood of individuals vaccinated with vaccinia virus more than 30 years ago. The peptides were characterized biochemically as high-affinity human leucocyte antigen (HLA) class I binders (K(D)
| Original language | English |
|---|---|
| Journal | Clinical and Experimental Immunology |
| Volume | 155 |
| Issue number | 3 |
| Pages (from-to) | 441-6 |
| Number of pages | 6 |
| ISSN | 0009-9104 |
| DOIs | |
| Publication status | Published - 2009 |
Bibliographical note
Keywords: Adult; Antibodies, Monoclonal; Antigen Presentation; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Enzyme-Linked Immunosorbent Assay; Female; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Immunologic Memory; Lymphocyte Activation; Lymphocyte Count; Male; Middle Aged; Protein Binding; Time Factors; Vaccination; Vaccinia virus; Variola virus
ID: 16052017